Treatment options

Greater initial VF loss is the most important predictor of blindness from glaucoma.
In a newly-diagnosed patient, the RoP is unknown and Target IOP is based on risk
factors for progression (see II.2.2.1). After sufficient follow-up and with sufficient VF
tests to reliably determine the progression status, usually 2-3 years, the importance of
the risk factors for decision-making decreases and importance of the measured rate
of progression increases; the RoP should be used to adjust the target IOP, taking into
account IOP levels over the observation period, life expectancy, and current levels of
visual function damage (See FC X).

FC X – Setting the target IOP

FC X – Setting the target IOP

Higher
target
IOP

Early Short High No Slow

Glaucoma Life Untreated IOP* Additional risk Rate of

damage expectancy factors Progression

Advanced Long Low Yes Fast

Lower The above factors need to be considered as a whole in

target
IOP deciding the individual target pressure required
* Consider central corneal thickness, status of the other eye, family history, patient preference and adverse
consequences of intervention.

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