A creeping annual or perennial herb known as Mimosa pudica Linn.

is frequently
grown for its curious compound leaves, which when touched fold inward and droop
and then instantly reopen. In the Legume family (Fabaceae) and its subfamily
Mimosoideae, the genus Mimosa contains roughly 400 species of herbs and shrubs.
The plant was first found in tropical America. Since then, it has spread to tropical and
subtropical parts of Asia.

in a study by Parasuraman et al. to examine the anti-diabetic and anti-hyperlipidemic

effects of a methanolic extract of Mimosa pudica (MEMP) on streptozotocin-induced
diabetes mellitus in Sprague-Dawley rats. Different volumes and dosages of a MEMP
were investigated for their potential antihyperlipidemic and antidiabetic benefits.
MEMP's antidiabetic capability was contrasted with that of glibenclamide (20 mg/kg
BW). Rats' body weights and blood glucose levels were monitored during the
experiment at regular intervals. The rats were slaughtered at the conclusion of the
experiment, and their organs were used for histopathological analysis after a blood
sample was taken for biochemical analysis. The diabetic control rats were studied for
the duration of the study. Throughout the course of the study, the diabetic control
group of rats displayed a significant increase in their levels of glucose, total
cholesterol (TC), triglycerides (TG), low-density lipoprotein (LDL), and very-low-
density lipoprotein (VLDL), compared to the control rats. In contrast, the animals
treated with glibenclamide and MEMP displayed a significant decrease in their levels
of glucose, TG, LDL, and VLDL. In conclusion, the rat model of streptozotocin-induced
diabetes mellitus was significantly improved by the methanolic extract of Mimosa
pudica. The return of blood glucose levels to normal levels is proof that the
antidiabetic capability of the methanolic extract of Mimosa pudica is comparable to
that of glibenclamide.

The blooming plant Cassia fistula, also known as "golden shower," belongs to the
Fabaceae family. The native range of the plant extends from southern Pakistan
through India and Sri Lanka to Bangladesh, Myanmar, and Thailand. It is also found in
nearby areas of Southeast Asia. In addition to being employed in herbal medicine, it
is also a well-liked decorative plant.

The hydroalcoholic extract of Cassia fistula showed notable hypolipidemic activity in

the Kaushal et al. 2020 trial. The weight of the mesenteric fat pads increased
significantly after receiving a high-fat diet. The improved thermogenesis and
decreased lipogenesis that were seen in groups of rats treated with Cassia fistula
hydroalcoholic extract may be responsible for the decrease in elevated fat pad
weight. The hydroalcoholic extract of Cassia fistula, which has been shown to have
antihyperlipidemic properties in albino rats, may represent a promising nutraceutical
therapy for the treatment of hyperlipidemia and the difficulties that can arise from
it.
1.  Group 1 (Controlled Group) animal feed and water.

2.  Group 2 (Negative control group)

3.) Group 3 (Standard Group: Atorvastatin 100 mg/kg)

4.  Group 4 (Experimental 1 Group: Ethanolic leaf Extract 100 mg/kg)

5.  Group 5 (Experimental 2 Group: Ethanolic leaf Extract 200 mg/kg)

6.  Group 6 (Experimental 3 Group: Ethanolic leaf extract 300 mg/kg)

30 female Sprague-Dawley rats will be used in this investigation, divided into six groups of five rats
each. Group 1 (Controlled Group: Animal Feed and Water). Group 2 (Negative control group). Group 3
(Standard Group: Atorvastatin 100 mg/kg). Group 4 (Experimental 1 Group: Ethanolic Leaf Extract 100
mg/kg). Group 5 (Experimental 2 Group: Ethanolic leaf Extract 200 mg/kg). Group 6 (Experimental 3
Group: ethanolic leaf extract 300 mg/kg). Triton X-100 (100 mg/kg) will be injected intraperitoneally
into Groups 2, 3, 5, and 6 in order to cause hyperlipidemia in Sprague-Dawley rats.Animals in groups 2
through 6 received their first dose of the medication treatment immediately following the delivery of
triton. After 24 and 44 hours, the second and third doses were given, respectively. Animals are
employed for the study of several biochemical parameters 4 hours after the third treatment. Under
anesthesia, blood was drawn from the rat's retroorbital plexus and centrifuged for 30 minutes at 2000
rpm to obtain the serum, which was then examined for biochemical markers.