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Last edited: 7/15/2022

8. ANTIMYCOBACTERIALS
Antimycobacterials Medical Editor: Donya Moslemzadeh

I) REVIEW QUESTIONS WITH ANSWERS

QUESTIONS ANSWERS

1) Which combination is suitable to treat MAC infection in an HIV+ c) Clarithromycin + Ethambutol + Rifabutin
patient?
a) Ethambutol + Azithromycin + Rifampin
b) Clarithromycin + Dapsone
c) Clarithromycin + Ethambutol + Rifabutin
d) Azithromycin + INH

2) Which one is not an adverse effect of Rifampin? a) Methemoglobinemia

a) Methemoglobinemia
b) Orange Urine
c) False Positive Opiates urine test
d) Decrease the efficacy of NNRTIs used to treat HIV

3) Which statement is true about the INH mechanism of action? d) Inhibits the synthesis of mycolic acid, an
essential component of the mycobacterial cell
a) Inhibits the production of Arabinogalactan, an essential component of
wall
the mycobacterial cell wall
b) Inhibits the RNA production
c) Inhibits the protein Synthesis by binding to Ribosome
d) Inhibits the synthesis of mycolic acid, an essential component of the
mycobacterial cell wall

4) Which multidrug regimen is used to treat Leprosy? b) Dapsone + Rifampin + Clofazimine

a) Rifampin + INH
b) Dapsone + Rifampin + Clofazimine
c) Rifampin + Ethambutol + Clarithromycin
d) Rifampin + Dapsone + INH

5) In a patient with Active TB and Gout which drug is not recommended c) Pyrazinamide
as part of TB treatment?
a) Rifampin
b) INH
c) Pyrazinamide
d) Ethambutol