Respiratory

System
Pathology

http://emedicine.Medscape.com/article/994274-overview

Nasal Polyp
Polypoid gelatinous mass with smooth outer surface,
filling the left nasal cavity.
 COLOR ATLAS of HISTOPATHOLOGY BY R.C.CURRAN

Nasal Papilloma: Exophytic (Fungating) Papilloma

Exophytic papillary growth pattern of benign looking epithelial cells.

(Mucosa)

https://path.upmc.edu/cases/case32.html

Nasal Papilloma: Inverted Papilloma

Inverted growth pattern of benign looking epithelial cells
forming masses of cells in the submucosa.
 COLOR ATLAS of HISTOPATHOLOGY BY R.C.CURRAN

Nasal Papilloma: Inverted Papilloma

Inverted growth pattern of benign looking epithelial cells
forming masses of cells in the submucosa.

Robbins Basic Pathology 9th edition

Acute Respiratory Distress Syndrome (ARDS): Lung

Intra -alveolar fibrin exudation and Hyaline membrane formation
(eosinophilic material lining the alveoli) (arrows).
 GROSS PATHOLOGY/ A COLOUR ATLAS
BY R.C.CURRAN and E.L.JONES

Bronchiectasis
Permanent dilation of bronchi and bronchioles forming prominent
cavities (arrows).It is caused by destruction of the muscle and
elastic supporting tissue.

COLOR ATLAS of HISTOPATHOLOGY BY

R.C.CURRAN

Bronchiectasis
Bronchiectatic cavities lined by respiratory epithelium and
filled with inflammatory exudate.
 GROSS PATHOLOGY/ A COLOUR ATLAS BY R.C.CURRAN and E.L.JONES

Centrilobular Emphysema
Slice of fixed inflated lung, the dilated air spaces are seen around the
center of the lobule(centrilobular) with normal looking lung tissue in-
between .

GROSS PATHOLOGY/ A COLOUR ATLAS BY R.C.CURRAN and E.L.JONES

Panacinar Emphysema
Slice of fixed inflated lung, the dilated air spaces are seen to involve
the alveolar ducts, alveoli and respiratory bronchioles, thus
involving the entire acinus (Panacinar). No normal lung tissue.
Lobar Pneumonia:
Consolidation that is
sharply confined to the
middle lobe of the lung
(arrows).
The affected lobe is
covered by greyish
fibrin, it is dry, firm,
grey and granular.

GROSS PATHOLOGY/ A COLOUR ATLAS

BY R.C.CURRAN and E.L.JONES

Lobar Pneumonia:
Grey Hepatization
4th – 8th day
Grossly
The affected lobe is
covered by greyish fibrin
Cut surface of the lobe
is dry, firm, grey and Grey hepatization
granular.

Robbins Basic Pathology 9th edition

 COLOR ATLAS of HISTOPATHOLOGY BY
R.C.CURRAN

Lobar Pneumonia: Red Hepatization

Congestion of the alveolar capillaries (thin arrow).
Alveolar spaces contain fine network of fibrin with large
number of neutrophils and RBC (thick arrow).

COLOR ATLAS of HISTOPATHOLOGY BY

R.C.CURRAN

Lobar Pneumonia: Grey Hepatization

No more congestion of the alveolar capillaries.
Alveolar spaces are filled by dense network of fibrin with
neutrophils and few RBC.
Bronchopneumonia:
Multiple foci of patchy
consolidation about 1 cm
in diameter which
appear to be centered
around bronchioles
(arrows).

https://webpath.med.utah.edu/LUNGHTML/LUNG006.html

Pathhsw5m54.ucsf.edu

Bronchopneumonia:
Multiple foci of patchy
consolidation about 1
cm in diameter which
appear to be centered
around bronchioles.
 GROSS PATHOLOGY/ A COLOUR ATLAS BY R.C.CURRAN and E.L.JONES

Simple Coal Worker Pneumoconiosis ( Focal Dust Emphysema): Lung

Patchy dilation of air spaces (centrilobular emphysema) with black
dust (coal) pigmentation.

GROSS PATHOLOGY/ A COLOUR ATLAS BY R.C.CURRAN and E.L.JONES

Silicosis: Lung
Multiple fibrous silicotic nodules in the upper zones of the
lung (arrows).
 GROSS PATHOLOGY/ A COLOUR ATLAS
BY R.C.CURRAN and E.L.JONES

Caplan's Syndrome: Lung

Multiple nodules up to 5 cm. in diameter scattered through out the
lungs of workers who are exposed to inhaled dusts.

GROSS PATHOLOGY/ A COLOUR ATLAS

BY R.C.CURRAN and E.L.JONES

Asbestosis: Lung- pleura

Diffuse fibrous thickening of the pleura around the lung (arrows).
 COLOR ATLAS of HISTOPATHOLOGY BY
R.C.CURRAN

Asbestosis- Asbestos Bodies: Lung

Complete fibers are surrounded by macrophages (yellow arrow) and
become coated with iron and protein derived from phagocyte ferritin
forming a drumstick shaped body called Asbestos body (black arrows).

Honeycomb Lung :
Diffuse interstitial
pulmonary fibrosis
with cystic spaces
develop in a fibrotic
lung.
This is the end stage of
most chronic
restrictive lung
diseases, irrespective
of the etiology.

Core Pathology by Alan Stevens, James Lowe and Ian Scott

 GROSS PATHOLOGY/ A COLOUR ATLAS
BY R.C.CURRAN and E.L.JONES

Malignant Mesothelioma
The tumor affects both visceral & parietal pleura forming diffuse
thickening of the pleura that ensheathes and invades the lung.

Robbins Basic Pathology 9th

edition

Squamous Cell Carcinoma: Lung

Large tumor arising in the right main bronchus (arrow).
GROSS PATHOLOGY/ A COLOUR ATLAS
BY R.C.CURRAN and E.L.JONES