TOPIC PRACTICUM -7

INTRODUCTION TO
REPRODUCTIVE HORMONE
DRUGS

TIM DOSEN
DIVISI REPRODUKSI & KEBIDANAN
DEPT. KLINIK REPRODUKSI DAN PATOLOGI
INSTITUT PERTANIAN BOGOR
SEMESTER GANJIL; MAHASISWA SKHB-IPB
LEARNING OUTCOME

After carrying out this practicum students:

Able capable students
• Identifying hormonal preparations for
reproduction on the market
• chemical grouping of reproductive hormones
• Describe the application of reproductive
hormone preparations
 INTRODUCTION
• HORMONE IS chemical substances that are synthesized and secreted
by endocrine glands / limited tissues in small amounts and
channeled through blood vessels / diffusion to tissue / target organs
and function to regulate specific / specific physiological functions

• By knowing the function and mechanism of action of hormones,

hormonal preparations can be used for
• therapy by VETERINARIAN
• livestock management needs (sexual synchronization) & embryo transfer
 WORK PROCEDURES
• Lecturer gives review of Primary Reproductive Hormone & introduction to practicum
• Students work in groups, noting the hormone preparations present for each group

• Create a temporary report – groups

• Reviewed the group temporary report by Practicum Assistant (Asprak)
• Asprak requests validation of the report from the practicum lecturer ( signature in the upper right
corner)

• Write individual final reports using group data that has been validated by practicum lecturers
• Entering a report accompanied by a photo of your group's temporary data that has been affixed
with the signature of the practicum lecturer (temporary report validation)
 MATERIALS AND TOOLS
• Computer /
Cellphone
• Information on
hormonal drugs from
groups of proteins,
steroids and fatty
acids from internet
searches
• Interim report (see
format)
Add 1 column for the hormone data source that you get from the internet
The work step records
the following
information:

1. Trade name
1.
2. Active substance

Gonadodrelin = GnRH Agonist

3. Factory
packaging

Bottle > 25 ml 4. Packaging (vials, ampoules,

bottles),
5. Packing volume,
vial / Flacon
< 25 ml 6. Serve form (solution,
Ampoule powder

7. Uses
8. Route of delivery
9. Storage
10. Expiry period
CIDR = CONTROLLED INTERNAL DRUG RELEASE
CIDR = CONTROLLED INTERNAL DRUG RELEASE
CIDR = CONTROLLED INTERNAL DRUG RELEASE
 REPORT TOPIC 7 HORMONE
• Individual Reports using striped folio paper
• The format of the report is incomplete.
• Write down the source of your report library
• Report in the form of a table with lanes based on the hormones chemical group :

1. Trade name, 6. Packaging (vials, ampoules,

2. Active substance, bottles),
3. Factory, 7. Serving form (solution, powder),
4. Uses, 8. Packing volume,
5. Route of delivery, 9. Storage,
10. Expitarion date
11. References
 Prostaglandins PGF2 and PGF2 analogue
Commercially available products:
• Dinoprost (Lutalyse, Upjohn Ltd, Crawley)
• Cloprostenol (Estrumate, Mallinck-rodt Veterinary, Harefield)
• Luprostiol (Prosolvin, Intervet UK Ltd, Cambridge)
• Tiaprost (Iliren, Hoechst Animal Health, Milton Keynes)
• Dinoprost (Noroprost, Norbrook) 5 mg/ml, cattle 25 mg i.m.
Cattle: sinkronisasi estrus, treatment non-visible oestrus, induksi
partus, induksi abortus, mumifikasi, pyometra, endometritis, luteal
cyst, CL persisten