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Andersson Et Al. - 2003 - Ceramic Implant Abutments For Short-Span FPDs A Prospective 5-Year Multicenter Study
Andersson Et Al. - 2003 - Ceramic Implant Abutments For Short-Span FPDs A Prospective 5-Year Multicenter Study
resistance shown when zirconia is compared to alu- years). Carious lesions were the most common reason
mina and other dental ceramics.17,18 Zirconia that is for tooth loss (31%), followed by periodontitis (27%).
biocompatible19,20 and capable of development21 is
regarded as an encouraging core material for implant Implants, Abutments, and FPDs
abutments, crowns, and FPDs. So far, however, no
clinical long-term follow-up studies are available. Initially, 105 Brånemark implants were placed. After
The aim of the present multicenter study was to pre- FPD connection, 53 ceramic abutments supported 19
sent and compare results after 5 years of loading of FPDs, and 50 titanium abutments supported 17 FPDs.
short-span FPDs supported by either CerAdapt ce- In all, 13 FPDs were placed in the maxilla (8 test, 5
ramic abutments or titanium abutments (Nobel control) and 23 in the mandible (11 test, 12 control).
Biocare), with regard to hard and soft tissue reactions. Three FPDs were placed in the anterior region (2
test, 1 control), 26 in the posterior region (10 test, 16
Materials and Methods control), and 7 (7 test) in both the anterior and pos-
terior regions. The FPDs in the test group were ce-
Study Design mented to the abutments, while the FPDs in the
control group were screw retained. The ceramic abut-
This was an open, prospective, randomized con- ments were prepared according to the manufacturer’s
trolled study for patients receiving short-span FPDs guidelines (Fig 1). The first abutment was placed in
supported by alumina or titanium abutments on August 1994, and the last in June 1996.
Brånemark system implants (Nobel Biocare). Sintered Clinical evaluation included a careful assessment
aluminum oxide abutments (CerAdapt; test group) of the peri-implant mucosa, gingiva, and pocket
were compared to established titanium abutments depth around implants and adjacent teeth. Further-
(control group). The study was carried out in accor- more, the position of crown edge in the peri-implant
dance with the Declaration of Helsinki.22 According sulcus and esthetics were evaluated. The examina-
to a randomization list,23 the patients received either tions were performed as previously described.5
test or control abutments. Patients who needed two
short-span FPDs received one FPD supported by ce- Statistics
ramic and one supported by titanium abutments.
Implants were followed for survival according to ac- Descriptive statistics and conventional life table
cepted criteria.24 The FPDs were recorded as suc- analysis with regard to cumulative success rates (CSR)
cessful when function and esthetics were accepted by have been used in the present study.23 The Mann-
patients and clinicians. All patients have been fol- Whitney U test was used for comparison of marginal
lowed for 5 years after loading, and this report pre- bone loss between the two abutment types. Test for
sents the final 5-year results. trend in contingency table (Mantel-Haenszel chi-
square)25 was used to analyze differences between
Patients the abutment types and between the adjacent teeth
regarding mucosal/gingival bleeding index and
The patients were consecutively included in the plaque. The statistical tests for the analysis of the
study, provided that they fulfilled the following in- marginal bone level were based on patient as the unit
clusion/exclusion criteria: (not on implants), ie, a mean of all loaded implants
was calculated per patient. For comparison between
• The patient was in such a physical and mental groups regarding dichotomous variables, the percent
condition that a 5-year follow-up period could be of surfaces with bleeding and plaque on abutment
expected. types and adjacent teeth, respectively, was calculated
• The implant site was healed properly. for each patient. Significance tests were two tailed
• The FPDs were to be supported by two to four im- and conducted at the 5% significance level.
plants.
• Cross-arch FPDs were not involved. Results
• The implants had not been previously loaded.
• Radiation therapy had not been carried out in Thirty of the 32 patients with 29 of initially 36 inserted
the treatment area. FPDs, 17 supported by ceramic abutments and 12 sup-
ported by titanium abutments, were examined after 5
A total of 32 patients at three clinics, 14 males and years. Of the 105 implants placed, 3 failed, giving an
18 females, were treated with 36 FPDs. The mean age overall implant survival rate of 97.1%. Two implants
at implant placement was 53 years (range 15 to 71 were nonosseointegrated before loading, and one failed
during the second year of loading. The latter implant supported FPDs were examined due to an administra-
loss was recorded in an FPD supported by four implants. tive mistake. One patient had two mandibular FPDs re-
The FPD was modified after implant removal and was made, as a change of occlusion was needed before
still in function after 5 years. One of the 53 ceramic and making a new prosthetic restoration in the maxilla.
none of the 50 titanium abutments failed, giving a CSR Minor abutment fractures, located at the most coro-
of 98.1% and 100%, respectively (Table 1). One of 36 nal part of the abutment, were recorded for two pa-
FPDs failed, giving an overall CSR of 97.2%. The CSR tients during the initial prosthetic work. The prosthetic
was 100% for 12 titanium abutment–supported and treatment was continued for both patients in spite of
94.7% for 17 ceramic abutment–supported FPDs after the incidents. One patient who was a heavy bruxer
5 years. The failure was due to a fractured abutment in had a porcelain fracture recorded on a mandibular
an FPD on two implants, where the opposing teeth had molar after 5 years. Two antagonist teeth were re-
been restored with porcelain since the last visit. The pro- ported as lost at the 1-year examination. One tooth
visionally cemented FPD was loose, and both the abut- in the opposing jaw had been replaced by an implant-
ment and FPD were recorded as failures after 1 year. supported crown after 2 years and another one after
Six FPDs in five patients were withdrawn. One patient 3 years. One opposing FPD abutment was changed
did not show up for recall visits in spite of repeated re- to a cantilevered one after 2 years, and a tooth-sup-
minders, and in three patients who had both ceramic- ported FPD in the opposing jaw was replaced by
and titanium-supported FPDs, only the ceramic- two implants after 3 years.
Table 1 Life Table Analysis of Ceramic Abutments and Fixed Partial Dentures (FPD) Supported by Ceramic Abutments
Abutments FPDs
Time period Successful Failed Withdrawn CSR (%) Successful Failed Withdrawn CSR (%)
30 30
Teeth (%)
Plaque, titanium abutments
Plaque, ceramic abutments
20 20
Bleeding, titanium abutments
Bleeding, ceramic abutments
10 10
0 0
0 1 2 3 4 5 0 1 2 3 4 5
Time (y) Time (y)
Fig 2 Soft tissue bleeding and plaque around abutments. Fig 3 Soft tissue bleeding and plaque around teeth adjacent
to ceramic and titanium abutments.
Plaque was more frequently seen than soft tissue 40 of 52 ceramic and 39 of 50 titanium abutments.
bleeding at the 1- to 5-year follow-up appointments. There was a mean marginal bone loss of 0.3 mm (stan-
No significant differences were recorded between ce- dard deviation [SD] 0.5) for the ceramic abutments and
ramic and titanium abutments for mucosal bleeding of 0.4 mm (SD 0.9) for the titanium abutments. The
and plaque (P ⬎ .05) (Fig 2). There were also no sig- marginal bone loss from baseline (FPD insertion) to the
nificant differences for gingival bleeding and plaque 5-year follow-up did not show any statistically signif-
when teeth adjacent to FPDs on ceramic and titanium icant difference between the two groups (P ⬎ .30).
abutments were compared after 5 years (Fig 3). The clinicians rated the esthetic result as excellent
Three pockets of 5 mm were recorded around two or good in 92% and acceptable in 8% of the cases
ceramic abutments at the 5-year examination. at FPD insertion. The results were comparable for ce-
Changes of the mucosal level were recorded at 12% ramic and titanium abutments with regard to the fre-
of the abutments. The level of the peri-implant mu- quency of FPDs that were rated excellent or good. At
cosa also showed some differences over time in re- the 5-year follow-up appointment, the correspond-
lation to the level of the abutment/crown (Table 2). ing figures were 100% and 0%. All patients were fully
More changes were recorded from FPD insertion to satisfied with the achieved esthetic results at both FPD
2 years (seven) than from 2 to 5 years (four). Seventy- insertion and the 5-year appointment.
three percent of all changes were recorded at ceramic
abutments. No pathologic mobility was recorded for Discussion
implants or adjacent teeth.
An independent radiologist used radiographs taken This study was a randomized controlled trial; there is
at FPD insertion and 1, 3, and 5 years later to analyze universal agreement that this study design constitutes
Table 2 Changes in Crown Margin Position from Fixed Partial Denture (FPD) Insertion to 5-Year Follow-up
Crown margin at FPD insertion Change from insertion to 2-y follow-up Change from 2- to 5-y follow-up
Position Ceramic Titanium Position Ceramic Titanium Ceramic Titanium
the best scientific evidence for treatment effective- though plaque was somewhat more often seen than
ness.26 There have only been a few follow-up studies bleeding. This indicates satisfactory oral hygiene, as
on the clinical outcome of ceramic abutments pub- there is a relationship among oral hygiene, bacterial
lished so far.5,13 This is surprising, as there is a great plaque accumulation, peri-implant mucositis, and
professional and commercial interest in implants and gingivitis.32 Abutments of both commercially pure ti-
ceramic materials in dentistry. An explanation for the tanium and high-density alumina have in experi-
lack of documentation might be that clinical follow- mental studies33,34 demonstrated a high quality of at-
up studies are very time demanding for both the re- tachment to the peri-implant mucosa.
search team and patients. The mucosal level, in relation to the level of the
Thirty of initially 32 patients remained after 5 years, abutment/crown, exhibited changes at 12% of the
since two patients did not complete the study. The abutments. Sixty-four percent of the changes oc-
number of patients completing the present study in- curred during the first 2 years, and 36% occurred dur-
dicates a high level of reliability for the obtained re- ing the last 3 years. Seventy-three percent of all
sults. The loss of patients is lower than the with- changes were recorded at ceramic abutments. There
drawal rate of 18% reported for a comparable 5-year was a balance between more or less exposures of the
multicenter implant study.27 crown margins during the first 2 years, in contrast to
No titanium and one ceramic abutment failed. the 2- to 5-year period, when all changes meant less
This failure, a fracture during the first year of loading, exposed margins. These results might indicate sys-
resulted in the loss of an FPD supported by two abut- tematic changes of the level of the peri-implant
ments. The brittleness of the ceramic abutment was mucosa over a longer period. The results support
considered to be the main reason for the fracture5 that previous observations on soft tissue changes at im-
finally resulted in the loss of the FPD. In a longer time plants,35,36 although it should be remembered that the
perspective (⬎ 5 to 10 years), however, the design,28 number of observations was limited in the present
brittleness,28 and tendency for ceramic materials to study.
undergo static fatigue29 have to be taken into ac- The radiographic examinations revealed a mar-
count regarding the prognosis. There was an overall ginal bone loss of 0.3 mm and 0.4 mm for titanium
CSR of 97.2% for the FPDs, based on a CSR of 100% and ceramic abutments, respectively. A steady bone
and 94.7% for FPDs on titanium and ceramic abut- level was maintained during the 5-year follow-up
ments, respectively. The success rates after 5 years period. These observations are in agreement with
were encouraging and support the good long-term those of previous studies.30,37,38
prognosis for implant-supported short-span FPDs.30,31 Both clinicians and patients rated the esthetics as ex-
Only minor changes were recorded for teeth oppo- cellent/fully satisfying for all treatments after 5 years.
site the followed FPDs. None of these changes were as- These ratings are surprisingly high compared to a re-
sessed to have had any influence on the outcome of the cent study on ceramic crowns.11 Those patients were
FPDs. No differences were recorded for plaque and soft followed for up to 10.5 years, and esthetics was rated
tissue bleeding when titanium and ceramic abutments as excellent according to 92% of patients and 59% of
were compared, and no pathology or complications clinicians. It is hard to find any explanation for the
were reported for the peri-implant mucosa or gingiva. 100% ratings in the present study, as clinicians usu-
A low level of plaque at FPDs and adjacent teeth ally are more critical than patients and also to some
was recorded during the follow-up period, even extent focus on other details than patients.39,40
32. Pontoriero R, Tonelli MP, Carnevale G, Mombelli A, Nyman SR, 37. Gunne J, Åstrand P, Lindh T, Borg K, Olsson M. Tooth-implant
Lang NP. Experimentally induced peri-implant mucositis. A clin- and implant supported fixed partial dentures: A 10-year report.
ical study in humans. Clin Oral Implants Res 1994;5:354–359. Int J Prosthodont 1999;12:216–221.
33. Abrahamsson I, Berglundh T, Glantz P-O, Lindhe J. The mucosal 38. Naert I, Koutsikakis G, Duyck J, Quirynen M, Jacobs R, van
attachment at different abutments. An experimental study in Steenberghe D. Biologic outcome of implant-supported restora-
dogs. J Clin Periodontol 1998;25:721–727. tions in the treatment of partial edentulism. Part II: A longitudinal
34. Berglundh T, Lindhe J, Ericsson I, Marinello CP, Liljenberg B, radiographic evaluation. Clin Oral Implants Res 2002;13:390–395.
Thomsen P. The soft tissue barrier at implants and teeth. Clin Oral 39. Carlsson GE, Ödman P, Ekstrand K, et al. An international com-
Implants Res 1991;2:81–90. parative multicenter study of assessment of dental appearance
35. Jemt T. Regeneration of gingival papillae after single implant using a computer-aided image manipulation. Int J Prosthodont
treatment. Int J Periodontics Restorative Dent 1997;17:327–333. 1998;18:246–254.
36. Jemt T. Restoring the gingival contour by means of provisional resin 40. Chang M, Ödman PA, Wennström J, Andersson B. Esthetic out-
crowns after single implant treatment. Int J Periodontics Restorative come of implant-supported single-tooth replacements assessed by
Dent 1999;19:21–29. the patient and prosthodontists. Int J Prosthodont 1999;12:335–341.
Literature Abstracts
This prospective study compared the clinical performance of a carbon fiber–reinforced carbon
(CFRC) endodontic post with that of a prefabricated precious alloy serrated parallel-sided post
(Parapost). Twenty-seven single-rooted maxillary anterior teeth in 18 patients were restored with
either post system. Type III gold-alloy cores were cast on the posts. Resin cement was used for
the CFRC posts, and zinc phosphate was selected for Parapost. The mean observation period
for all patients was 87 months (range 80 to 100 months). In the CFRC group (n = 16), four ce-
mentation failures were found at 24, 29, 56, and 87 months, respectively, and two patients were
lost to recall at 16 and 31 months, respectively. In the control group (n = 11), only one fractured
post was encountered at 84 months, and two patients were lost at 19 and 24 months, respec-
tively. Lost patients were not included for statistical analysis. Kaplan-Meier survival curves
demonstrated that survival of CFRC posts was lower than that of controls from 24 months. Bond
failure appeared to occur between the resin luting cement and internal dentin in all failed CFRC
restorations, but it is impossible to determine the cause. The use of contemporary dentin adhe-
sives in conjunction with resin luting cement may improve the retention of CFRC.
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Division of Restorative Dentistry, University of Bristol Dental School, Bristol, United Kingdom. e-mail:
j.s.rees@bristol.ac.uk—Frederick C. S. Chu, Hong Kong
This study compared clinical parameters of immediately loaded and nonloaded implants at sec-
ond-stage surgery. Outcome measurements were conducted on clinical stability and changes of
marginal bone level within 6 months. Fourteen immediately loaded implants were compared with
28 nonloaded implants. Selection criteria for the subjects were patient driven in that patients de-
clared the need for retentive prostheses. Six Frialit-2 stepped screws were placed between the
mental foramina, with two exposed to the intraoral cavity for immediate loading with a Dolder
bar–retained overdenture. Implants were evaluated for implant survival, Periotest value, and
change of clinical marginal bone level between first- and second-stage surgery. The Mann-
Whitney U test was used to evaluate statistical significance. Median Periotest values were –3 for
the loaded and –6 for the nonloaded implants, which was highly significant but still within the nor-
mal range of osseointegrated implants. Six months postoperative, there was a 1-mm reduction in
peri-implant bone height for loaded implants and a 0.5-mm reduction for nonloaded implants. This
difference was also highly significant. No implant failures were noted within this time period.
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Reprints: Dr Martin Lorenzoni, Department of Prosthetic Dentistry, School of Dental Medicine, Karl-Franzens-
University Graz, Auenbruggerplatz 12, A-8036 Graz, Austria. e-mail: Martin.Lorenzoni@uni-graz.at—
Josephine Esquivel-Upshaw, San Antonio, Texas