NycoCard Reader for

Av a i l a b i l i t y
®
Quantitative Determination of
1100296 NycoCard U-Albumi n. 24 tests
1109559 NycoCard ® U-Albumi n Control, 2 x 1.0 mL
®
1042184 NycoCard HbA1c, 24 tests
HbA1c
1113022 NycoCard ® HbA1c Control, 2 x 0.4 mL
1047778 NycoCard ® READER II kit U-ALBUMIN

CRP
D-DIMER

Ny coCard ® READER II HbA1c

On e instrument, four tests Mi croalbumi n
D-Dime r
C-reactive protein

References
1) New Engl J Med 329:977-986, 1993 (340)
2) Lancet 352:837-853, 1998 (2210)
3) Lancet 854-865, 1998 (2220)
4) BMJ 317:703-713, 1998 (2230)
5) BMJ 317:713-720, 1998 (2240)
6) JIFCC 9(2):62-68, 1996 (760)
7) Clinical Chemistry 28(10):2088-2094,1982 (1400)
8) Clinical Chemistry 39(8):1717-1723, 1993 (300)
9) Clinical Chemistry 29(3):543-545, 1983 (1410)
10) Exp Clin Endocr & Diab 107(4):244-251, 1999 (5390)
11) Ann Med 29:439-445, 1997 (2050)
12) Diabetes Care 21 (7) : 1076-1079, 1998 (5060)
13) New Engl J Med 341 (15):1127-1133, 1999 (5560)
14) J Hypertension 14 (Suppl 2):S89-S94, 1996 (1630)

3 minutes' test time

AX IS-SHI ELD PoC AS

AXIS-SHIELD Par t of the Ax is-Shield Gr oup

P.O. Box 6863 Ro deløkka

N- 0504 Os lo, No rway
Telephone +47 22 04 20 00
Fax +47 22 04 20 01
www .axis-shield-poc.com

Exclusively Mktd. By:

RAPID DIAGNOSTIC PVT. LTD. (INDIA) The ways to improve AXIS-SHIELD

(ISO 9001:2000 CERTIFIED C O M PA N Y )

B - 159, Gujranwala Town-I, Delhi-9 Ph.: 7247508, Fax: 7413437 Email : drjindal@vsnl.com health care
Test procedure
1. Drop 5 µL capillary with
patient blood sample into the
R1/Dilution Liquid tube-Mix
throughly for 10 seconds
2. Apply 50 µL diluted sample to the
test well. Allow to soak (approx
30 seconds).
3. Apply 1 drop R2/Conjugate
to the test well. Allow to soak
(approx 30 seconds).
4. Apply 1 drop R3/Washing Solution
to the test well. Allow to soak
(approx 20 seconds).
5. Read the result within 5 minutes
Use the CRP Whole Blood menu
for reading blood samples and the
CRP Serum/Plasma menu for
reading serum or plasma samples
and the C/Control
NycoCard® CRP Single Test Test procedure NycoCard® D-Dimer
Determines C-Reactive Protein in serum, plasma Determines fibrin degradation product D-Dimer
and whole blood in plasma
What is C-Reactive Protein?
· An acute phase protein produced in the liver
· Increases rapidly after stimuli onset
· Pathological concentrations reached after 6-12 hours
1. Apply 50 µL of washing
· Maximum level reached within 24-48 hours solution (R2) to the test hole.
· Pathological values up to 1-2 weeks after stimuli onset Allow the washing solution
to soak into the card.
· May increase 100-1000 times during the acute phase
· Correlates well to the degree of the disease
· Decreases rapidly after removal of stimuli
CRP measurements has proven to be useful in
the following clinical situations:
· “Screening” for an infection
· Monitoring extent and activity of disease
2. Apply 50 µL of undiluted platelet-
· Differential diagnosis free citrated plasma or Control (C)
· Monitoring bacterial complications to diseases to the pre-wetted test hole. Allow the
sample to soak into the card in less
· Post-operative infectious complications than 50 seconds.
· Monitoring effect of therapy
· As a risk indicator for cardiovascular diseases
How to evaluate the CRP result
· 0 -10 mg/L - Normal concentration
· 10 - 25 mg/L - Increased but diagnostically of less importance During
antibiotic treatment CRP should be reduced below this 3. Apply 50 µL of conjugate (R1)
level. Does not exclude bacterial infection if the to the test hole and allow the
conjugate to soak into the card
disease has lasted short. Take a new sample some in less than 50 seconds.
hours later
· 25 - 50 mg/L - There is “something”. Bacterial or viral?
· 50 - 100 mg/L - Occurs infrequently with viral infections
- Common in bacterial infections
· > 100 mg/L - Seldom seen with viral infections
Fairly common in bacterial infections
Advantages of Nycocard CRP Single Test: 4. Apply 50 µL of washing
With a quantitative and rapid point-of-care CRP test, the physicians have a solution (R2) to the test hole
and allow the solution to soak
valuable tool to avoid unnecessary prescription of antibiotics to patients with into the card.
viral, or probably self-limiting superficial bacterial infection.
Characteristics
Measuring range : Whole blood samples : 8-250mg/L
Serum or plasma sample : 5-150mg/L
Sample Material : 5 µL of whole blood/serum/plasma
Test Principle : Solid phase, sandwich-format, 5. Read the result within two
immunometric assay using a gold antibody minutes using
conjugate. Nycocard READER II
Expected values : Normal values < 6mg/L