Omalanthus macradenius is a traditional Mindanao herb.

The leaves are

used by Agusan’s Manobo to treat cuts and wounds, as well as impetigo,
diarrhea,and stomach disordersThe leaf ethanolic and methanolic extract of
Omalanthus macradenius was evaluated for its cytotoxic potential against human
red blood cells, antibacterial activity against S. aureus and P. aeruginosa, and
phytochemical component. Standard protocol for phytochemical analysis and
cytotoxic assay were followed. Hemolysis assay showed that Omalanthus
macradenius methanolic and ethanolic leaf extract under 1 000, 10 000, 20 000
ppm concentration has no toxic effect on red blood cells. The phytochemical
screening of Omalanthus macradenius ethanolic leaf extract revealed the
presence of alkaloids, flavonoids, phenols and tannins, glycosides, and
phytosterols. Whereas methanolic leaf extract revealed the presence of alkaloids,
flavonoids, phenols and tannins, carbohydrates, and phytosterols. The disc
diffusion assay and the antibacterial OD readings showed that the ethanolic and
methanolic leaf extract has no antibacterial activity against Staphylococcus
aureus and Pseudomonas aeruginosa. This study, concluded that Omalanthus
macradenius is non-toxic and do not have antibacterial activity against
Staphylococcus aureus and Pseudomonas aeruginosa.

Keywords: Omalanthus macradenius, Hemolysis assay, Disc Diffusion assay,

Antibacterial OD readings, and Phytochemical screening.
 Medicinal plants have long been used in traditional and ethnomedicine all
around the world (Hao, 2019).