PakI International Nursing College 8.

Cri du chat is a result of a(n):

Paper: pathphysiology 2 (4rth semester) a.inversion
b.translocation
1.The innate tendency of offspring to resemble to their c.deletion
parents is called: d.duplication
a.variation 9.when a bottom segment of one chromosome attaches
b.heredity to homologue a(n)……….occurs
c.inheritance a.duplication
d.resemblence b.deletion
2.Basic unit of inheritance are: c.inversion
a.chromosomes d.both a and b
b.Nucleus 10.The sex chromosomes of human female are:
c.Nucleolous a.xx
d.Genes b.xy
3.Patau syndrome is associated with trisomy of c.yy
chromosome: 11.polyploidy generally results from:
a.13 a.mutation
b.15 b.hybirdization
c.18 c.non dysjunction
d.21 12.Monosomy is presented as:
4.Edward syndrome is associated with trisomy of a.2n+1
chromosome: b.2n+2
a.13 c.2n+3
b.21 d.2n-1
c.15 13.Trisomy is presented as:
d.18 a.2n-1
b.2n+1
c.2n+3
5.Down syndrome is associated with trisomy of d.2n-1
chromosome: 14.Somatic cells in humans have……….chromosomes?
a.13 a.23
b.21 b.46
c.15 c.92
d.18 15.Bilateral cleft lip and palate,malformed ears and
6.Rocker-bottom heel is associated with: congenital heart disease are the clinical features of:
a.patau syndrome a.Patau syndrome
b.Edward syndrome b.Downsyndrome
c.Down syndrome c.Turner syndrome
d.none of the above 16.Clenched hands with overlaping fingers in which
7.In humans there are …….pairs of autosomes? occipitor back part of skull is prominent are the clinical
a.22 features of:
b23 a.Patau syndrome
c.44 b.Edward syndrome
d.88 c.Turner syndrome
d.Downsyndrome c.none of the above
17.Protuding tongue,epicanthic folds,simian crese,gap 24.Tetany and paresthesia are the diseases caused by:
between 1st and 2nd toe are clinical features of: a.Hypoparathyroidism
a.Patau syndrome b.Hyperparathyroidism
b.Edward syndrome c.Both a and b
c.Turner syndrome 25.Hypothalamic hormones that are regulating hormones
d.Downsyndrome are:
18.Tall stature,poor muscle tone,Gynaecosmatia,reduced a.GH-releasing hormone
secondary sexual characteristics are clinical features of: b.Somatostatin
a.KLIEN FELTERS SYNDROME c.Somatomedin-IGF-1
B.Down syndrome d.All of the above
c.Turner syndrome 26.Which gland is located just superior to kidneys:
19.Who determines the sex of the child? a.Pitutary
a.The male b.adrenal
b.The female c.pancreas
20.Polyploidy generally results from: d.ovaries
a.mutation 27.The posterior pituatory stores and release
b.hybirdization a.Growth hormone and prolactin
c.non dysjunction b.prolactin and oxytocin
21.A post thyroidectomy patient develops signand c.oxytocin and antidiuretic hormone(ADH)
symptoms of tetany the management is: d.ADH and growth hormone
a.IV Calcium gluconate 28.A condition in which the attained height is well below
b.Bicarbonate the fifth percentile or linear growth is below normal for
c.Calcitonin age and sex is?
d.Vtamin D a.Dwarfism
22.What are the active thyroid hormone secreted by b.Gignatism
folicular epithelial cells: c.Acromegaly
a.tri-iodothyroxineT3 and tetra-iodothyroninT4(thyroxine) d.All of the above
b.tri-iodothyroxine T3 29.The Zona reticularis region of adrenal gland produces
c.Tetra iodothyronin T4(Thyroxine) which hormone?
23.Calcitonin function is: a.sex hormones Androgens
a.lower blood calcium by inhibiting the bone resorption b.Cortisol
and inhibiting the calcium recovery from renal tubule c.Cortisone
ultrafiltrate 30. The Zona glomerulosa region of adrenal gland
b.increase the blood calcium by increasing bone produces which of the following hormones:
resorptiom and increasing the calcium recovery from renal a.Mineralocorticoids,Aldosterone
tubule ultafiltrate b.Glucocorticoids : cortisol, cortisone
c.increase the blood calcium by increasing bone resorption c.Sex hormone
and inhibiting the calcium recovery from renal tubule 31.In stress condition which hormone is released in
ultrafiltrate circulatory system?
23.The enzyme involve in conversion of a.Androgens
cholecalciferol(vit D3)to calcidiol in liver is b.cortisol
a.alpha hydroxylase c.Mineralocorticoides
b.25-hydroxylase 32.What is the active form of vitamin D?
a.calcidiol a.79-160mg/dl
b,Calcitriol b.50-100mg/dl
c.Ergocalciferol C.20-90mg/dl
33 A child of 14 yearz came name ahmad to hospital had 41.In Hyperglycemia hyperosmolar state what pysilogical
followeing symptoms .Turnical obesity,moon effects occur in body
face ,buffalow hump,stretch marks,thin vulnerable skin a. Blood becomes thin causes diereses
impaired wound healing (which diseeease he is suffering b .Blood becomes viscous causes diuress
from?) c. blood preasure rises and risk of hemorrhage increases
a.Cushings syndrome 42.The major artries that supply blood to brain and spinal
b.Myxedema cord are:
c.Acromegaly a.Vertebro basilar artry
34.Another patient came to ayub teaching hospital name b.common carotid artry
nasir had elevated serum acth levels with inadequate c. posterior communicating artry
corticosteroides synthesis and secretion(He is suffering d.a and b
from which disease?) d.b and c
a.Addisons disease 43.How much cardic output of heart is going to CNS?
b.Cushings syndrome a.15%
c.Turner syndrome b.20%
D.Down sybndrome c.45%
35.Absorption of calcium in the body is increase by : 44.Circle of WILLS is present in:
a. Vitamin D a. subarachnoid space
b.Vitamin K b .Dura matter
c.Vitamin E c.CNS
d.none of the above d. Pia matter
36.Scientific names of both types of Diabetes are: 45.What are the fibers that produce pain perception and
A .Brittle diabetes and insulin dependent diabetes its name?
b. Type 1 and Type 2 a.Alpha gama fibers,mechanoreceptors
C .Juvenile diabetes and Adult onset diabetes b.C fibers,nociceptors
37.which type of diabetes occurs by lesion in Beta cells of d.Alpha gama and C fibers ,nociceptors
pancreas ,autoimmune mechanism and viral infection 46.Posterior cerebral artry supply blood to:
a.Type 1 DM a. cerebrum
b.Type 2 DM b. cerebellum
C.Both types c. cerebrum and Mid brain
38.Which of the given complication of DM is life 47.Abrevation of PICA is:
threatening? a.Posterior internal carotid artry
a.Diabetic coma b.Posterior inferior cerebellar artry
b.Diabetic retinopathy c.posterior inferior cerebral artry
c.Diabetic foot 48.Abrevation ofAICA is:
39.Gestational diabetes in females occurs due to a.Anterior inferior cerebellar artry
a.Secretion of Fetoplacental hormones b.Anterior internal carotid artry
b. Testosterone c.Anterior inferior common carotid artry
c. oxytocin 49.What are the stimuli that can excite pain receptors
40 What is the value of .Normal random blood sugar (nociceptors)?
level ? a.Thermal,Electrical
b.Thermal,Chemical b.Tight junctions of endothelial cells
c.Mechanical,Thermal,Chemical c.Thin layer of endothelial cells
59.Rapidly developed clinical sigh of focal disturbance of
50.What are the name of FAST pain fibers? cerebral function of presumed vascular origin and of
a.Alpha gama fibers more than 24 hrz is the definition of:
b.C fibers a.Hypertension
c.Alpha and beta fibers b.Diabetes mellitus
51.What is the duration of pain generated by slow pain c.Stroke
fibers? d.Intracranial preasure
a.After 1 sec 60.Transient ischemic attack recovery occurs in
b.o.1 sec a.64 hrz
c.0.2 sec b.24 hrz
52.The brain pain control pathways are: d.12 hrz
a.The pain modulation pathways
b.The endogenous opiate system 61.Inability of a person to speak occurs in a person by
c.pain removal pathway damage to which side of brain?
d.both a and b a.Right side
53.The endogenous opiate system work to combat pain b.Left side
in body by secretion of………… c.Occipital lobe
a.Endorphin 62.Hemmoragic stroke occurs due to:
b.Calcitonin A,Obstruction in artries by formation of emboli
c.Hystamin and bradykinin b.Leakage of blood vessels
54.Which node controls the electrical impulses generated c.Increase in Blood preasure
in heart? d.B and C
a.S A node e.a,c.b
b.A V node 63.The artries which carry deoxygenated blood to heart
c.none of the above are:
55.What is the name of main feeder that supply blood to a.superior vena cava
anterior spinal artry? b.Inferior vena cava
a.Great Medullary artry of ADAM c.pulmonary artries
b.Posterior spina l artry d.a and b
c.Subclavin artry e.b and c
56.What is the amont of CSF that is formed per day? 64.bicuspid valves are located in which chamber of heart:
a.200ml a.Right atrium
b.400ml b.Left atrium
c.600ml c Right ventricle
d.500ml d.Left ventricle
57.CSF is found in which of the meanings of brain? 65……………Law states that The heart has intrinsic
a.Pia matter ability to adopt itself to changing loads of inflowing
b.Dura matter blood or With in pysiological limits the heart pumps all
c.subarachnoid space the blood that comes to it without causing excess
d,.none of the above damage of blood in veins:
58.The central components of Blood brain barrier are: a.Frank starling law
a. Loose junctions of endothelial cells b.Mareys law
c.none of the above
66.Which disease of eye occurs due to preasure build up
by aqueous humour in eye that finally damages optic
nerve?
a.Cataracts
b.Glucoma 1 B
c.colour blindness 2 D
67. what are the types of glucoma disease? 3 A
a.open-angle glucoma 4 D
b.Narrow angle glucoma 5 B
c.wide- angle glucoma 6 A
d.a and b 7 A
e.b and c 8 C
68.Ischemic heart disease is a condition in which there is 9 C
lack of blood and…….supply to a portion of myocardium: 10 A
a.oxygen 11 C
b.pottasium ions 12 D
c.calcium ions 13 B
14 B
15 A
16 B
69……………. Is the disease in which plaque made of 17 D
fat ,cholestrol or calcium builds up in blood vessels? 18 A
a.Cirrhosis 19 A
b.Athreoslerosis 20 C
c.Haemolytic anemia 21 A
70.wHich of the given is antipatket drug used in 22 A
MyOCARDIAL INFACTION? 23 B
a.Aspirin and clopidogril 24 A
b.Panadol
25 D
26 B
d.Gravinate
27 C
28 A
29 A
30 A
31 B
32 A
33 A
34 A
35 A
36 C
37 A
38 A
39 A
40 A
41 B
42 D
43 A
44 A
45 D
46 C
47 B
48 A
49 C
50 A
51 A
52 D
53 A
54 B
55 A
56 D
57 C
58 B
59 C
60 B
61 B
62 D
63 D
64 C
65 A
66 B
67 D
68 A
69 B
70 A