Course title: HAEMATOLOGY AND BLOOD TRANSFUSION

Course code: LHT 220:

Hours taught: 4 units or 160 hours
1. Purpose of the course:
This course is designed to enable the student to study the normal haematology, the
common haematologic disorders and blood transfusion services; and also to take part in
conducting haematologic and blood transfusion related tests and the interpretation of the
findings.
2. Expected learning outcome:
By the end of this course, the student should be able to do the following:
1. Describe the process of haemopoiesis and the functions of the
formed elements and plasma.
2. Describe and explain the various types of common haematologic
disorders
3. Describe the various blood group systems and their application in
Blood Transfusion.
4. Participate in running of blood Transfusion services
5. Carryout the various haematological and blood transfusion tests and
interpret the findings.
3. Course content
a. Development of formed elements:
o Erythropoiesis,
o leucopoiesis,
o thrombopoiesis
b. Structure and functions of the formed elements;
o plasma components and their uses;
o haemoglobin;
o RBC destruction and
o bilirubin metabolism
c. Anaemia/Leukaemia/Coagulation disorders:
 o Definition,
o aetiology,
o investigation and
o classification.
d. ABO/CDE (Rhesus) and other blood group systems;
o antibody screening and identification;
o compatibility testing;
o haemolytic disease of the new born;
o Investigation of blood transfusion reactions.
e. Blood transfusion service:
o Organisation,
o blood donor recruitment,
o selection and bleeding;
o blood screening for transmissible diseases;
o storage of the blood;
o Transportation and distribution.
o Preparation and characteristics of the various blood products.
o Management of blood bank.
f. Hematology parametric analysis
o Red blood cell count;
o White blood cell count – total and differential;
o platelet count;
o haemoglobin estimation,
o PCV,
o staining of bone marrow and blood films,
o separation and concentration of blood cells,
o reticulocyte count,
o morphology of formed elements;
o haemoglbin electrophoresis,
o coagulation techniques,
 o platelet function tests.
g. Blood transfusion parameters
a. Blood grouping,
b. compatibility tests,
c. combs test,
d. preparation of various blood products for transfusion;
e. antibody screening and identification,
f. LE cells,
g. Investigations for blood transfusion reaction.
4. Mode of delivery:
Student centered approach, modified problem based learning in which the lecturer and
the student takes part in getting the solutions to problems under review, Class-room
teaching/briefing, student seminars, course work, Internet searches and international
data-base usage, self-directed learning, Laboratory practical for hands on skill acquisition
5. Instructional materials/equipment:
Computers with fast internet, LCD projectors, Transparencies, overhead projectors, Lap-
tops, white-board markers, Power-point Microsoft office 2007, Text books, Journals,
periodical.
6. Assessment methods
 Continuous assessment (40%);
 End of Semester (50%) which shall comprise of the following MCQs, short
answer types and essay questions.
 Practical Report (10%)
 Total (100%); the pass mark is 50% of the total mark.
7. Reading list
1. Essential Haematology by A. V. Hoffbrand, JE Petit & PAH Moss.
2. Clinical Hematology Atlas, W.B. Saunders Co., 2004 Rodak, B. F.
3. Monica Cheesbrough, Part 2. Second Ed.