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Drug Calculations Reviewer For Nurses
Drug Calculations Reviewer For Nurses
This is your study guide to help you refresh or review what you know about drug
dosage calculations including tips on how to answer them.
1 grain (gr) 60 or 65 mg
Standard Method
o The commonly used formula for calculating drug dosages.
o Where in:
D = Desired dose or dose ordered by the primary care
provider.
H = dose on hand or dose on the label of bottle, vial,
ampule.
V = vehicle or the form in which the drug comes (i.e.,
tablet or liquid).
STANDARD FORMULA
Example:
Order: Acetaminophen 500 mg
On hand: Acetaminophen 250 mg in 5 mL
Computation:
Example:
Answer: 10 mL
H : V = D : x
Example:
Order: Erythromycin 750 mg
On hand: Erythromycin 250 mg capsules
Computation:
250 (H) : 1 (V) = 750 (D) : x
250x = 750
x=3 capsules
Answer: 3 capsules
Example:
Order: Digoxin 0.25 mg
On hand: Digoxin 0.125 mg tablets
Computation:
Answer: 2 tablets
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2. Question
A patient has a bottle of warfarin (Coumadin) 5 mg tablets at home. After his most
recent international normalized ratio (INR), the doctor calls and tells him to take 7.5
mg/day. How many tablet(s) should the patient take? Fill in the blanks.
4. Question
The physician orders alprazolam (Xanax) 0.5 mg PO. You have on hand Xanax 0.25
mg tablets. How many tablet(s) will you give? Fill in the blanks.
5. Question
You need to administer 250 mg of erythromycin (Erythrocin) PO. You have on hand
0.5 g tablets. How many tablet(s) will you give? Fill in the blanks.
6. Question
You have available lorazepam (Ativan) 0.5 mg tablets, and you need to administer 1
mg PO. How many tablet(s) will you administer? Fill in the blanks.
8. Question
The physician writes a “now” order for codeine 45 mg IM for a patient with a
vertebral compression fracture. You have on hand codeine 60 mg/2 mL. How many
milliliters should you give? Fill in the blanks.
9. Question
You have on hand hydromorphone (Dilaudid) 4 mg/mL. You need to administer
0.015 mg/kg to a patient who weighs 150 pounds. How many milliliters should you
administer? Fill in the blanks. Record your answer using two decimal places.
11. Question
A patient has a primary IV of dextrose in water 1,000 mL to be infused over 24
hours. What would be the drip rate (ggts/min) using tubing with a drop factor of
60? Fill in the blanks.
12. Question
Your patient needs 2,000 mL of saline IV over 4 hours for severely deficient fluid
volume. How many milliliters per hour will you set on a controller? Fill in the
blanks.
13. Question
Your patient needs 2,000 mL of D5W IV over 24 hours, to be delivered with a tubing
set with a drop factor of 15. How many drops per minute will you set for an infusion
rate? Fill in the blanks.
Correct answer: 21 gtts/minute
Computation:
14. Question
You need to administer furosemide (Lasix) 2 mg/minute via continuous IV infusion
on a controller. Pharmacy has sent a bag of Lasix 400 mg diluted in D5W 250 mL.
How many milliliters per hour will you set on the controller? Fill in the blanks.
15. Question
The physician orders an IV with heparin at 700 units/hour. You have a bag with 100
units/mL of solution. How many milliliters per hour will you set on the IV infusion
controller? Fill in the blanks.
1. Question
A health care provider orders acetaminophen (Tylenol) supp 1 g pr q 6 hr prn temp
> 101. Available: Tylenol supp. 325 mg (scored). How many supp. will you
administer? Fill in the blank. Record your answer to the nearest whole
number.
Correct answer: 3 supp.
Computation:
2. Question
A nurse practitioner prescribes clindamycin (Cleocin) Oral Susp 600 mg po qid; Directions
for mixing: Add 100 mL of water and shake vigorously. Each 2.5 mL will contain 100 mg of
Cleocin. How many tsp of Cleocin will you administer? Fill in the blanks. Record your
answer to the nearest whole number.
3. Question
A health care provider ordered sulfasalazine (Azulfidine) Oral Susp 500 mg q 6 hr;
Directions for mixing: Add 125 mL of water and shake well. Each tbsp will yield 1.5 g
of sulfasalazine. How many mL will you give? Fill in the blanks.
4. Question
A health care provider prescribes potassium chloride (Klotrix) 0.35 mEq/ lb po
dissolved in 6 oz of oj at 8 am; Available: Klotrix 8 mEq/mL. How many mL of Klotrix
will you add to the oj for a 20.5 Kg patient? Fill in the blanks.
5. Question
A health care provider orders megestrol (Megace) Oral Suspension 160 mg po bid;
Directions for mixing: Add 100 mL of water and shake vigorously. Each 0.5 mL will
contain 10.7 mg of Megace. How many tbsp of Megace will you administer? Fill in
the blanks. Record your answer using one decimal place.
6. Question
A health care provider prescribes hydroxyzine (Vistaril) Oral Susp 10 mg q 4 hr prn anxiety;
Directions for mixing: Add 125 mL of water and shake well. Each tsp will yield 15 mg of
Vistaril. How many mL will you give? Fill in the blanks. Record your answer using one
decimal place.
7. Question
A health care provider prescribes ondansetron (Zofran) 8 mg p.o. t.i.d.; Available:
Zofran in a 100 ml bottle labeled 4 mg/tsp.; How many ml will the nurse administer
for each dose? Fill in the blanks.
Correct answer: 10 ml
Computation:
Formula:
Solution:
8. Question
A health care provider orders cefaclor (Ceclor) 45 mg/kg/day p.o. in 3 divided doses
for a patient who weighs 66 pounds. A 75 ml stock medication is labeled Ceclor 125
mg/ml. How many ml would the nurse administer per dose? Fill in the blanks.
Record your answer using one decimal place.
Formula:
Solution: 45 mg/kg/day x 30 kg = 1.350 mg/day ÷ 3 doses = 450 mg per dose
9. Question
You are providing home care for a patient who needs 15 mL of magnesium
hydroxide/aluminum hydroxide (Maalox) PO. She has only standard measuring
spoons in the house. How many tablespoon(s) do you instruct her to take her
dose? Fill in the blanks. Record your answer to the nearest whole number.
10. Question
You have on hand ergocalciferol (Calciferol) liquid 8000 units/2 mL. Your order
reads ergocalciferol 225,000 units PO daily. How many ml should you prepare the
correct dose? Fill in the blanks. Record your answer to the nearest whole
number.
Correct answer: 56 ml
Computation:
11. Question
Amoxil (amoxicillin) suspension 180 mg PO bid is ordered for a patient who cannot
swallow pills. It is supplied as 125 mg/5 mL. How many milliliters should you
administer? Fill in the blanks. Record your answer using one decimal place.
12. Question
You have an order for phenobarbital (Luminal) 50 mg PO at bedtime. It is supplied
as phenobarbital elixir 20 mg/5 mL. How much in mL will you administer? Fill in the
blanks. Record your answer using one decimal place.
13. Question
You are caring for your ill grandmother at home. She has an order for magnesium
hydroxide/aluminum hydroxide (Maalox) 10 mL PO prn stomach upset. How do you
instruct her to measure her dose in tsp using household measuring spoons? Fill in
the blanks.
You need to administer 400 mg of erythromycin (Erythrocin) PO. You have on hand a
suspension of 125 mg/5 mL. How many ml will you prepare? Fill in the blanks.
15. Question
Your patient has a headache but has difficulty swallowing pills. The physician orders
acetaminophen (Tylenol) 1000 mg PO every 4 to 6 hours prn. You have
acetaminophen elixir 160 mg in 5 mL. How much will you administer? Fill in the
blanks. Record your answer using two decimal place.
16. Question
A patient is instructed to take acetaminophen (Tylenol) liquid (elixir) 650 mg qid.
The elixir is 160 mg/5 mL. How many milliliters per dose should the patient
take? Fill in the blanks.
18. Question
A homebound patient must take 400,000 units of nystatin PO every 4 hours, to
swish in the mouth, and then swallow. It is available as 100,000 units/5 mL. The
patient has only household measuring spoons. How should the patient be
instructed to take the dose? Fill in the blanks.
19. Question
A health care provider prescribes ceftazidime (Fortaz) mg/kg/day p.o. 50 mg/kg p.o.
t.i.d. to a child who weighs 25.5 kg. Fortaz is available in an oral suspension labeled
100 mg/ml. How many ml would the nurse administer per dose? Fill in the blanks.
Record your answer using one decimal place.
Formula:
Solution:
20. Question
A nurse was instructed by a physician to give clarithromycin (Biaxin) for a child
whose BSA is 0.55 m2. The usual adult dose is 500 mg. Biaxin is available in an oral
suspension. The 100ml bottle is labeled 50 mg/ml. How many ml would the nurse
give per dose? Fill in the blanks. Record your answer using one decimal place.
Formula:
BSA Formula:
Solution:
1. Question
A health care provider prescribes kanamycin (Kantrex) 7.5 mg/kg IM q 12 hr;
Available: kanamycin 0.35 Gm/mL. How many mL will you administer for each dose
to a 157 lb patient? Fill in the blanks. Record your answer using one decimal
place.
2. Question
A health care provider orders Heparin 7,855 units subq bid; Available: Heparin
10,000 units per ml. How many mL will you administer? Fill in the blanks. Record
your answer using two decimal places.
3. Question
A health care provider prescribes meperidine (Demerol) 50 mg IVP q 6 hr prn pain;
Available: Demerol 75 mg/ 1.3mL. How many mL will you administer? Fill in the
blanks. Record your answer using one decimal place.
4. Question
A health care provider orders Streptomycin 1.75 mg/ lb IM q 12 hr; Available:
Streptomycin 0.35 g / 2.3 mL. How many mL will you administer a day to a 59 Kg
patient? Fill in the blanks.
5. Question
A health care provider prescribes bumetanide (Bumex) 0.8 mg IV bolus bid;
Reconstitution instructions: Constitute to 1000 micrograms/3.1 mL with 4.8mL of
5% Dextrose Water for Injection. How many mL will you administer? Fill in the
blanks. Record your answer using one decimal place.
Incorrect
Correct answer: 2.5 mL.
Computation:
1 mg = 1,000 mcg
6. Question
A health care provider orders ceftazidime (Tazidime) 0.3 g IM tid; Reconstitution
instructions: For IM solution add 1.5 mL of diluent. Shake to dissolve. Provides an
approximate volume of 1.8 mL (280 mg/mL). How many mL will you give? Fill in the
blanks. Record your answer using one decimal place.
7. Question
A health care provider orders Tobramycin 1.25mg/Kg IM q 12 hr; Available:
Tobramycin 0.2 g/mL. How many mL will you administer to a 183 lb patient for each
dose? Fill in the blanks.
8. Question
A health care provider prescribes Heparin 4,390 units Sub Q bid; Available: Heparin
5,000 USP units per ml in 10 ml. How many mL will you administer? Fill in the
blanks.
9. Question
A health care provider orders Penicillin G 223,500 units IM q 4 hr; Available:
Penicillin G 500,000 units /2.5 mL. How many mL will you administer? Fill in the
blanks. Record your answer using one decimal place.
Answer: (1.1) mL.
Incorrect
10. Question
A health care provider orders amikacin (Amikin) 5 mg/ lb IM q 12 hr; Available:
Amikacin 0.9 gm/ 2 mL. How many mL will you administer to a 72.7 Kg patient? Fill
in the blanks. Record your answer using one decimal place.
Answer: {1.8) mL.
Correct
11. Question
A health care provider orders fentanyl (Sublimaze) 0.05 mg IV bolus; Reconstitution
instructions: Constitute to Fentanyl 100 micrograms/2.3 mL with 2.4 mL of 5%
Dextrose Water for Injection. How many mL will you administer? Fill in the blanks.
Record your answer using one decimal place.
Answer: (1.2) mL.
Incorrect
12. Question
A health care provider prescribes cefazolin (Ancef) 0.4253 gm IM bid; Reconstitution
instructions: For IM solution add 1.25 mL of diluent. Shake to dissolve. Provides an
approximate volume of 1.6 mL (240 mg/mL). How many mL will you give? Fill in the
blanks. Record your answer using one decimal place.
Answer: (1.8) mL.
Incorrect
Answer: (0.6) mL.
Incorrect
Formula:
Solution:
14. Question
A health care provider orders Morphine gr 1/10; Available: Morphine 10 mg/ml.
How many ml will the nurse give? Fill in the blanks. Record your answer using
one decimal place.
Answer: (0.6) mL.
Incorrect
Formula:
Solution:
15. Question
A health care provider orders promethazine (Phenergan) for a child whose BSA is
1.2 m2. The usual adult dose is 25 mg. How many milligrams would the nurse
administer for the dose? Fill in the blanks. Record your answer using one
decimal place.
Answer: (17.6) mg
Incorrect
Solution:
16. Question
A patient with complaints of chest pain is ordered to receive diltiazem (Cardizem) 5
mg IVP. The vial contains 10 mg/2 ml. How many ml will you give? Fill in the
blanks.
Answer: (1) mL.
Incorrect
17. Question
Lanoxin (digoxin) 125 mcg is ordered IVP every a.m. The vial contains 0.5 mg in 2
ml. How many ml will you give? Fill in the blanks. Record your answer using one
decimal place.
Answer: (0.5) mL.
Incorrect
18. Question
A pre-op patient is ordered Atropine gr. 1/150 IM. The vial contains Atropine 0.4 mg
in 1 ml. How much in ml will you give? Fill in the blanks.
Answer: (1) mL.
Incorrect
19. Question
A patient with bacterial infection is ordered ceftazidime (Fortaz) 250 mg IM. The vial
contains 500 mg powder with directions to add 1.5 ml of sterile water for a total
volume of 1.8 ml. How many ml will you administer? Fill in the blanks. Record
your answer using one decimal place.
Answer: (0.9) mL.
Incorrect
20. Question
You need to administer prochlorperazine (Compazine) 10 mg IM to a nauseated
patient. You have on hand Compazine 5 mg/mL. How many ml would you
administer per dose? Fill in the blanks. Record your answer to the nearest
whole number.
Answer: (2) mL.
Incorrect
1. Question
Your patient has had the following intake: 2 ½ cups of coffee (240 mL/cup), 11.5 oz
of grape juice, ¾ qt of milk, 320 mL of diet coke, 1 ¼ L of D5W IV and 2 oz of grits.
What will you record as the total intake in mL for this patient? Fill in the blanks.
Answer: (3,265) mL.
Incorrect
Answer: (3,195) mL.
Incorrect
3. Question
Your patient had the following intake: 2 1/2 bowls of broth (180 mL/bowl), 1 can of
tomato juice (4.5 oz/can ), 4 oz of cottage cheese, 1 ¾ L of NS IV and ½ pt of ice
cream. What will you record as the total intake in mL for this patient? Fill in the
blanks.
Answer: (2,585) mL.
Incorrect
4. Question
Your patient has had the following intake: ½ cup of hot tea (240 mL/cup), 3/4
container of grapefruit juice (4 oz/container), 3/4 qt of milk, 1 pt of water, 125 mL of
D5W IV x 8 hr and 2 oz of fruit cocktail. What will you record as the total intake in
mL for this patient? Fill in the blanks.
Answer: {2,460) mL.
Correct
5. Question
You evaluate a patient’s intake and output for 8 hours. Intake for 8 hours:
6. Question
You are providing home care for a patient who needs to mix her oral psyllium
hydrophilic mucilloid (Metamucil) in 180 mL of water or juice. She has only standard
measuring cups in the house. How many cup(s) do you instruct her to take her
dose? Fill in the blanks.
Answer: (¾) cup(s)
Incorrect
7. Question
A patient with HIV infection is receiving 200 mg of didanosine (Videx) PO bid. The
pharmacy only has powder packets with 167 mg each, to be mixed with 4 oz of
water. How many packets should the patient mix? How much should the patient
take? How can it be measured? Fill in the blanks. Record your answer using one
decimal place.
Answer: (4.8) oz
Incorrect
or
8. Question
A hospitalized patient with heart failure is on a 1000 mL fluid restriction each 24
hours. During the 7 a.m. to 7 p.m. shift, he has three meals, consuming 1/2 cup of
coffee with each. He also has 50 mL of water each time he takes his medications at
7 a.m., noon, and 5 p.m. Mid Afternoon, he drinks 240 mL of soda. How many
milliliters may he consume during the 7 p.m. to 7 a.m. shift? Fill in the blanks.
Answer: (250) mL.
Incorrect
9. Question
You are providing home care for a patient who needs to mix her oral potassium
supplement with 120 mL of water or juice. She has only standard measuring cups in
the house. How do you instruct her to take her dose? Fill in the blanks.
Answer: (½) cup(s)
Incorrect
Correct answer: B. No
Rationale:
First, convert items to mL.
240 mL + 90 mL + 180 mL + 240 mL + 240 mL + 120 mL + 120 mL = 1,230 mL
No, he has exceeded his fluid restriction limit by 230 mL