Education

1997 : SMAK Depkes Makassar

Dr. Miswar Fattah, MSi
Makassar, 6th June 1978
Current position
2002 : Chemistry - UNHAS
2006 : Master of Science in Clinical Chemistry,
Biomedicine- UNHAS
2012 : Doctor of Medicine – Clinical chemistry,
UNHAS

1. Member of KTKI, 2022 - 2023

2. Specialty & Research Laboratory Manager,
3. PATELKI : Vice President of PATELKI 2017-2021 & Member of Collegium PATELKI 2015 – 2021
4. IACC Scientific division Reference Interval & Decision limit, Indonesian Association for Clinical Chemistry 2013- Now
5. President of AACLS 2018 - Now
CURRENT AND PROSPECTIVE APPLICATIONS OF
ARTIFICIAL INTELLIGENCE IN HEALTHCARE

Jakarta, 11th May 2023

Dr. Miswar Fattah, MSi

Konsil Teknik Biomedika
miswarfattah@gmail.com
 FUTURE
HEALTHCARE

SMART
PATIENT

We NEED Smart
healthcare professional
to face future
healthcare
CHANGING HEALTCHCARE ENVIROMENT

Kpmg 2018
PATIENT CENTER FOR FUTURE HEALTHCARE
 ANALOGY OF MULTI-LAYER GOOGLE MAPS AND PATIENT INFORMATION GOES TO
PRECISION MEDICINE

https://newsroom.fmcna.com/whitepapers/personalized-nephrology
Geographic Information System
of a Human Being

(Topol E, 2014)
 ARTIFICIAL INTELLIGENCE
• AI: The broadest term, applying to any Artificial
technique that enables computers to Intelligence
mimic human, i.e. “natural”
intelligence.
Machine Learning
• ML: A subset of AI that includes
abstruse statistical techniques that
enable machines to improve at tasks
with experience.
• DL: The subset of ML composed of
Deep Learning
algorithms that permit software to
train itself to perform tasks, by
exposing multilayered neural networks
to vast amount of data.
DEEP LEARNING
Learns from data
and uses a deep
hierarchy of layers
to make
predictions
WHY NOW?
• Computer power
• Dramatic gains in computer
processing power
• Advances in mathematical
algorithms
• Years of research led to
modern neural networks
framework
• Large labeled datasets
• Access to large amounts of
data used for algorithmic
training
POTENTIAL APPLICATIONS OF QUANTUM COMPUTING FOR
HEALTHCARE
Sundar Pichai and Daniel Sank with a Google quantum computer
 AI APPLICATIONS ACROSS INDUSTRIES AND BUSINESS FUNCTIONS

1. K. Burt, ChatGPT / Artificial Intelligence: What it means for investors. LVW Advisors (2023), (available at https://lvwadvisors.com/thought-leadership/chatgpt-artificial-intelligence-what-it-means-for-investors/).
RECOGNIZED AS TOP 100 AI STARTUP BY CB INSIGHTS
• Jason Allen’s A.I.-generated work, “Théâtre D’opéra Spatial,” took
first place in the digital category at the Colorado State Fair
• Mr. Allen created his artwork with Midjourney, an artificial
intelligence program that turns lines of text into hyper-realistic
graphics.
• A.I.-generated art has been around for years. But tools released
this year — with names like DALL-E 2, Midjourney and Stable
Diffusion — have made it possible for rank amateurs to create
complex, abstract or photorealistic works simply by typing a few
words into a text box.
Monalisa work from home
“Sorry, can you repeat
your question?” Source:
AI-generated image
using DALL-E with the
prompt ‘AI robot in a
white coat lecturing
human doctors in a
large auditorium,
Vincent Van Gogh-style’.
• Picture presenting GPT-4 with an X-ray and asking, “What
do you see in the X-ray, and where?” GPT-4 could then
potentially examine the image, pinpoint a lesion, and
offer a precise location and description
AI: WHAT MOST PEOPLE THINK ABOUT

Self-driving Personal Recognizing

cars assistants images
Artificial
Intelligence
FACE
RECOGNIZER
AI IMAGE RECOGNIZE FOR BUSINESS & SECURITY
AI INTEGRATED CCTV
AI for safety driving
 THE EMERGENCE OF AI IN HEALTHCARE WILL LIKELY GO TROUGH
FOUR PHASE

PWC.com
THE HUMAN ELEMENT IN ARTIFICIAL INTELLIGENCE

• Artificial intelligence seems poised to revolutionize

healthcare
• Right now, 15% of medical decision-making in care
delivery is automated
• We would like it to be 80 to 85% that is automated
• There’s no substitute for a clinician.
• It’s really the inverse of what we need the clinician’s brain
to do
THE PROMISE OF SUPERCOMPUTERS
• To find cures for disease
• Identify vulnerable patients before they become ill, or better
personalize testing and treatments
• Research is moving fast to apply computing power to
healthcare problems large and small.
• At the same time that clinical laboratorians are exploring
analytics to mine the wealth of data available to labs
• clinicians are seeking to streamline processes and boost their
diagnostic and predictive abilities with advanced algorithms
and supercharged software
AI ROBOT AS POLICE
ARTIFICIAL INTELLIGENCE ROBOT

SHOFIA, The advanced

artificial intelligence
robot, which looks like
Audrey Hepburn,
mimics human
expressions and may be
the Next Generation of
robots that solve the
world’s most complex
problems
SHOFIA AS SPEAKER AT CONFERENCE & GUEST
SOPHIA INTERVIEW VIDEO
• Sophia excels at natural language conversations
• ChatGPT can instantly generate its answers in nearly any
written form--including lists of medical answer
• ChatGPT concurred with Sophia that advances in natural
language processing will make it easier for A.I. systems to
understand and respond to a wider range of human
language and input
NOW ROBOT AI CHANGE MEDICINE
AI ROBOT PASSED MEDICAL LICENSING EXAM

• Xiaoyi, an AI-powered robot

in China
• Taken the national medical
licensing examination &
passed, making it the first
robot to have done so
• Help patients, answer more
questions per day compare
human physician
VIDEO OF ROBOT AI EXAMINATION

AFTER EXAMINATION NOW AI ROBOT WORK AT HOSPITAL

XIAOYI FIRST ROBOT AS MEDICAL DOCTOR
VIDEO AI ROBOT WORK AT HOSPITAL
XIAOYI AND HUMAN INTERACTION
AI is transformative for healthcare
at every level
THE STATE OF
ARTIFICIAL
INTELLIGENCE-
BASED FDA-
APPROVED
MEDICAL
DEVICES AND
ALGORITHMS:
AN ONLINE
DATABASE

1. S. Benjamens, P. Dhunnoo, B.
Meskó, npj Digit. Med. 3, 1–8 (2020).
AREA OF AI MEDICINE

Chatbots
Oncology Pathology
medicine

Rare Genetic
Diseases data
AI IN APPLICATION RADIOLOGY
IMAGE AT MEDICINE: POTENTIAL AI ROLE
FIRST RADIOLOGY REPORT VS. 2018 REPORT
https://physicsworld.com/a/artificial-intelligence-versus-101-radiologists/
1. W.-Y. Ip et al., Artificial Intelligence in Medical Imaging. 2, 37–55 (2021).
THE SECURE NATIONWIDE AI-POWERED CLOUD PLATFORM STREAMLINES CARE TEAM
COMMUNICATION AND DELIVERS PATIENT-SPECIFIC IMAGING INSIGHTS WITHIN CLINICAL
WORKFLOWS
TRAINING AND PREDICTION OF
PANCREATIC CANCER RISK
FROM DISEASE TRAJECTORIES

1. D. Placido et al., Nat Med, 1–10 (2023).

The world of GAI
entrepreneurs is
growing rapidly
as use cases
expand, as this
sample of six
companies
suggests
THE PROSTATE SEGMENTATION PIPELINE.
THE MULTI-ORGAN AI PIPELINE
HEALTH SYSTEMS AND HOSPITALS APPEAR TO BE ABLE TO LEVERAGE CHATGPT TACTICALLY,
BUT THE REAL DIFFERENCE IS WITH GAI
STEPS OF THE RT PATIENT-BASED WORKFLOW, IN WHICH AI-BASED
TECHNIQUES CAN BE APPLIED.
GENERALIST MEDICAL ARTIFICIAL INTELLIGENCE

• LLMs/generative AI/foundation models

1. M. Moor et al., Nature. 616, 259–265 (2023).

APPLICATIONS OF AI IN THE RADIATION THERAPY WORKFLOW
STAFF INVOLVEMENT AND PATIENT-FACING STEPS IN THE
RADIATION THERAPY WORKFLOW
 POTENTIAL IMPLICATIONS OF APPLYING AI IN RADIATION
ONCOLOGY FOR MEMBERS OF THE RADIATION THERAPY
WORKFORCE

AI will probably disrupt this profession substantially in the long term 1. E. Huynh et al., Nat Rev Clin Oncol. 17, 771–781 (2020).
 SMILE

SMILE

SMILE
SMILE
AI IMAGE RECOGNIZER IN LABORATORY MEDICINE
• AI-Powered Microscope
Counts Malaria Parasites
in Blood Samples
• a Chinese manufacturer
and a venture backed by
Bill Gates announce to
commercialize a
microscope that uses
deep learning algorithms
to automatically identify
and count malaria
parasites in a blood smear
within 20 minutes
AI POWERED MICROSCOPE TO COUNT MALARIA
SMART MICROSCOPE: TRAINING AI TO ‘READ’ BLOOD

• Shonit can analyse 120

views of blood smear
samples to arrive at a more
accurate diagnosis in just
10 minutes against 20
views in 30 minutes by a
human pathologist
AI SMART MICROSCOPE IS BEST IMAGINED AS A DECONSTRUCTED
HUMAN PATHOLOGIST
AI: BLOOD COUNT & MALARIA
AI FOR INTERPRETATION IN LABORATORY MEDICINE

• Laboratory medicine is huge data

generator
• 1 human genome sample 120 GB
• The future of possibilities for AI
in the field of clinical
biochemistry are numerous,
particularly in the context of
multi-analyte panels for
metabolites, proteins, and genes
 Preanalytical, analytical,
Primary Disease 19728
post analytical, material Disease Disease
of control, Role statistic,
Type of error, Quality of >20
people, IQA, EQA etc Sample Whole blood,
Quality serum, plasma,
Type urine, saliva,
breast milk,
semen, faecal,
artery, capillary,
Biomarker Fluids, Hair, cord

120509 blood, tissue etc

1115
Geriatric, adult, Assay
pediatric, Pregnancy, Cutoff RI Instrument, reaction,
Method Manufacturer

Time &
biological
https://gobiomdb.com/
Variation Fasting, non fasting, acute, chronic, early morning
https://edrn.nci.nih.gov
Night, posisition etc
https://www.malacards.org
AI: SMART BLOOD ANALYTIC
AI FOR INTERPRETATION IN LABORATORY MEDICINE
• Automated interpretations may add to and refine existing roles,
but AI will have a limited impact on the interpretative role of
Clinical Chemists, because that role is currently limited
• Interpretative algorithms and large datasets are likely to be of
immediate use for quality, standardization, and reference
intervals
• Expert systems could be used in the near future to simplify
interpretation of rare and complicated disease workups
AI IN GENOMIC
 GENOMIC IS A BIG DATA PROBLEM

1 Exabyte = 4,803,839,602,528 books = 245,146,535 4.38GB DVD’s

AI AND MACHINE LEARNING APPLICATIONS IN GENOMICS

Genome
Gene Editing
Sequencing

Direct-to-
Clinical
Consumer
Workflow
Genomics
CURRENT ROLE OF AI IN GENOMIC
• Genome Sequencing : to help researchers interpret genetic
variation. Specifically, algorithms are designed based on patterns
identified in large genetic data sets
• Gene Editing: Machine learning offers the capability to significantly
reduce the time, cost and effort necessary to identify an
appropriate target sequence
• Clinical Work flow : There are often gaps in the patient data
available to the different members of a healthcare team serving a
patient. More efficiently integrate genetics in breast cancer
treatment and patient care
• Direct-to-Consumer Genomics: helping individuals interpret their
test results
112
https://codegen.eu

113
GENETIC PREDICT MY BALDNESS
http://genotation.stanford.edu/
FUTURE TALK OF PEOPLE ABOUT THEIR GENE
“The greatest opportunity offered by AI is not reducing
errors or workloads, or even curing cancer: it is the
opportunity to restore the precious and time-honored
connection and trust —the human touch—between
patients and doctors.”
amyotrophic lateral sclerosis, a
neurodegenerative disease that
eventually causes most people to
lose their ability to speak, walk or
breath.

Voice Keeper, which is one of several

companies using artificial intelligence
to “bank” people’s voices while they
are still able to speak and re-creates
those voices for text-to-speech
software
INTEGRATING AI INTO EDA TOOLS FOR PCB DESIGN
ARTIFICIAL INTELLIGENCE
THRIVING IN THE AI REVOLUTION: EIGHT ESSENTIAL INSIGHTS FOR
NAVIGATING THE CHATGPT ERA

AI won't make you AI will impact your Generative AI can

AI is already here
redundant – at job, business, or enhance your work
and all around us
least not yet industry and efficiency

Ethical and AI will redefine AI has the Balancing AI's

explainable AI is education and skill potential to solve benefits and risks
vital development global challenges is crucial

1. B. Marr, Thriving in the AI Revolution: Eight Essential Insights for Navigating the ChatGPT Era. Bernard Marr (2023),
FIVE POINTS THAT ENTREPRENEURS INTERESTED IN INTEGRATING
ARTIFICIAL INTELLIGENCE INTO THEIR BUSINESS MODELS

Identify the Consider the

Understand the
problem or potential risks and
capabilities and
opportunity that ethical
limitations of A.I
A.I. can help with implications

Plan for the Monitor and

integration and evaluate the
adoption process results
THE AI REVOLUTION IN HEALTH CARE: HOW ENTREPRENEURS ARE
TRANSFORMING PATIENT CARE WITH INNOVATIVE SOLUTIONS

Streamlined
Precision medicine Precision medicine Telemedicine and
workflow and
and personalized and personalized remote patient
resource
care care monitoring
management.

Predictive analytics
Accelerated drug
Enhanced mental and population
discovery and
health support health
development
management
 AI PIONEERS: TRANSFORMING HEALTHCARE ONE INNOVATION AT A
TIME

Aidoc: Tempus: a Atomwise: AI- Nanox: a new Ada Health: AI- Intuitive Biofourmis: Woebot: AI-
pioneering AI data-driven powered drug era of medical driven virtual Surgical: harnessing AI enabled
in medical approach to discovery and imaging with health elevating for remote mental health
imaging personalized development AI integration assistants for surgical patient support for the
medicine patient precision monitoring digital age
Nanox partners empowerment through AI-
with Qure.ai to enhanced
integrate AI- robotics
based algorithms
for medical
imaging in the
Nanox.CLOUD
CHATBOT ADA HEALTH : AI AND MACHINE LEARNING TO TRACK PATIENT HEALTH AND OFFER
USERS A BETTER UNDERSTANDING OF CHANGES TO THEIR HEALTH
JENDELA PENGETAHUAN
 Perbanyak melihat Jendela Kehidupan
Dengannya kita akan lebih mudah termotivasi
Menggapai impian yang lebih baik
CONCLUSIONS

• The potential combined impact of digital images and

artificial intelligence (AI) on the future of pathology and
radiology
• Now artificial intelligence implemented in recognize
image in laboratory medicine
• Laboratory medicine as data generator using AI to
interpretation of large omics data
THANKYOU