calyx

Intermediates Structure CAS No. API

4'-Bromomethyl-2-
biphenylcarbonitrile
Bromo OTBN) 114772-54-2 Sartans
.r

4'-[(2-Butyl-4-oxo-1,3 bC

-diazaspiro[4.4]non-1-en-3- O

yl)methyl]biphenyl- 138401-24-8 Irbesartan

N
N
2-carbonitrile
(Cyano-Irbesartan) H 3C
PHARMA INTERMEDIATES

bC
HO
4'-((2-Butyl-4-chloro-5- Cl
114772-55-3 Losartan
(hydroxymethyl)-1H-imidazol-1-yl) N
N
methyl)biphenyl-2-carbonitrile
H 3C

(1-((2'-(1H-Tetrazol-5-yl) Cl
OH
N
N

bH

biphenyl-4-yl)methyl) H 3C
N N

-2-butyl-4-chloro-1H- N 114798-26-4 Losartan

imidazol-5-yl)methanol

L-Valine, N-[(2'-cyano Me
b
PhH 2CO2C Me
[1,1'-biphenyl]-4-yl)
137864-23-4 Valsartan
methyl]-, NH

phenylmethyl ester HCl

L-Valine, N-[(2'-cyano[1,1' Me
b
PhH 2 CO2 C Me
-biphenyl]-4-yl)methyl] 137864-22-3 Valsartan
-N-(1-oxopentyl)-, N

phenylmethyl ester O
Me

L-Valine, N-(1-oxopentyl) Me
N
N

N
PhH 2 CO2 C Me
-N-[[2'-(2H-tetrazol-5-yl) N
137863-20-8 Valsartan
[1,1'-biphenyl]-4-yl]methyl]-, b

phenylmethyl ester O
Me

CH3
2-Cyano-4'-(2'n-propyl-4-methyl-6'- N CH3

(1-methylbenzimidazol-2'-yl) N b

benzimdazol-1-ylmethyl) N CN 144702-27-2 Telmisartan

CH3
biphenyl
 calyx

Intermediates Structure CAS No. API

Methyl 4'-[[2-propyl-4-methyl-6- CH 3
C H3
N
(1-methylbenzimidazol-2-yl N b
benzimidazol-1-y N O O 528560-93-2 Telmisartan
CH 3 C H3
l]methyl]biphenyl-2-carboxylate

2-(n-Dibutylamino)-1- OH
Bu2N
(2,7-dichloro-9H-fluoren-4-yl) 69759-61-1 Lumefantrine
ethanol
/l Cl
PHARMA INTERMEDIATES

(S)-2-((2-Amino-6-oxo-1,
6-dihydropurin-9-yl)methoxy) O
N
ethyl 2-(benzyloxycarbonyl) HN
O 124832-31-1 Valacyclovir
H2 N N H
-3-methylbutanoate N
O h
N O

N-Carbobenzyloxy- O

L-valinyl-gancyclovir HN N
O 194154-40-0 Valgancyclovir
H2 N N N H
N O
O h
O
HO

Calyx Chemicals and Pharmaceuticals Limited

CIN:U24220MH1986PLC038618
Corp. Office: A37 / 38 MIDC Phase - 1, Golavli, Kalyan-Shil Road, Dombivili (East), Dist. Thane - 421203
Maharashtra, India
Email: sales@calyxindia.com, crams@calyxindia.com www.calyxindia.com

USA Contact: 11728 E. Imperial Highway, Norwalk, CA 90650, Tel - 213-291-7773

Email: sales@calyxindia.com, crams@calyxindia.com, sales@calyxusa.com, crams@calyxusa.com, www.calyxindia.com