DR Noman Bin Abid

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NOMAN BIN ABID, Ph.D.

Al-Abid Clinic Noor-e-wali, Rahim Yar Khan.


Cell: +92 3038557760,
E-mail: noman@wustl.edu
mnomanabid@gmail.com
https://orcid.org/0000-0001-6929-8878

Academic qualification:

• Ph.D.: Applied Life Sciences (Neurobiology) (2014 - 2018)


Gyeongsang National University, South Korea
• M.Phil: Molecular Biology (2005 - 2007)
CEMB, University of the Punjab, Lahore, Pakistan.
• M.Sc: Zoology (2002 - 2004)
University of the Punjab, Lahore, Pakistan.

Professional Research Experiences:

• Post Doc. Research Associate: (Oct 2021-Jan 2023)


Department of Neurosurgery; Washington University in St. Louis.
Research Project:
o Epigenetics regulation in Huntington's disease.
• Senior Researcher (Post Doc.): (Sep 2018 - Aug 2020)
Gyeongsang National University, Jinju-Si, South Korea.
Research Projects:
o Age-dependent, gene expression profiling of Alzheimer’s Disease.
o Role of peripheral metabolism in Brain.
• Research Associate/Lab Instructor: (Jan 2010 - Mar 2013)
Lahore University of Management Sciences. Lahore, Pakistan.
Research Projects:
o Establishing a microinjection facility to generate transgenic organisms.
• Research Associate: (Aug 2007 - Aug 2008)
Shaukat Khanum Memorial Cancer Hospital & Research Centre, Lahore, Pakistan
o Genotyping of Hepatitis A virus in Pakistani Population.
• Research Assistant: (Jun 2008 - Dec 2008)
University of Veterinary Animal Sciences
Research Projects:
o Prion disease as a model for the multi-purpose experimental platform; a rational
approach to reducing experimental cost.
Publication:

1- NB Abid, MI Naseer, MO Kim, Comparative Gene-Expression Analysis of Alzheimer’s


Disease Progression with Aging in Transgenic Mouse Model. International Journal of
molecular sciences 20 (5), 1219.
2- Abid, N.B., G. Yoon, and M.O. Kim, Molecular Cloning and Expression of Osmotin in
a Baculovirus-Insect System: Purified Osmotin Mitigates Amyloid-beta Deposition in
Neuronal Cells. Sci Rep, 2017. 7(1): p. 8147.
3- Ali T, Rehman SU, Khan A, Badshah H, Abid NB, Kim MW, et al. Adiponectin-mimetic
novel nonapeptide rescues aberrant neuronal metabolic-associated memory deficits in
Alzheimer's disease. Mol Neurodegeneration. 2021;16(1):23.
4- Jo MG, Kim MW, Jo MH, Bin Abid N, Kim MO. Adiponectin homolog osmotin, a
potential anti-obesity compound suppresses abdominal fat accumulation in C57BL/6
mice on high-fat diet and in 3T3-L1 adipocytes. Int J Obes (Lond). 2019;43(12):2422-
33.
5- A Ahmad, T Ali, MW Kim, A Khan, MH Jo, SU Rehman, MS Khan, NB Abid,
Adiponectin homolog novel osmotin protects obesity/diabetes-induced NAFLD by
upregulating AdipoRs/PPARα signaling in ob/ob and db/db transgenic mouse
models, Metabolism 90, 31-43
6- Rabia Mukhtar Rana, Shailima Rampogu, Noman Bin Abid, Amir Zeb, Shraddha
Parate, Gihwan Lee, Sanghwa Yoon, Yumi Kim, Donghwan Kim and Keun Woo Lee,
“In Silico Study Identified Methotrexate Analog as Potential Inhibitor of Drug
Resistant Human Dihydrofolate Reductase for Cancer Therapeutics” Molecules 2020,
25, 3510; doi:10.3390/molecules25153510
7- Ahmad, Abid N B, M O Kim., Neuroprotection by Vitamin C Against Ethanol-Induced
Neuroinflammation Associated Neurodegeneration in the Developing Rat Brain. CNS
Neurol Disord Drug Targets, 2016. 15(3): p. 360-70.
8- H Badshah, T Ali, A Ahmad, M J Kim, N bin Abid, S A Shah, G H Yoon , Co-Treatment
with Anthocyanins and Vitamin C Ameliorates Ethanol- Induced Neurodegeneration via
Modulation of GABAB Receptor Signaling in the Adult Rat Brain. CNS Neurol Disord
Drug Targets, 2015. 14(6): p. 791-803.
9- MS Khan, T Ali, MN Abid, MH Jo, A Khan, MW Kim, GH Yoon, EW Cheon., Lithium
ameliorates lipopolysaccharide-induced neurotoxicity in the cortex and hippocampus of
the adult rat brain. Neurochem Int, 2017. 108: p. 343-354.
10- MW Kim, N Bin Abid, MH Jo, MG Jo, GH Yoon, MO Kim , Suppression of adiponectin
receptor 1 promotes memory dysfunction and Alzheimer's disease-like pathologies. Sci
Rep, 2017. 7(1): p. 12435.
11- SU Rehman, A Ahmad, GH Yoon, M Khan, MN Abid, MO Kim, Inhibition of c-Jun N-
Terminal Kinase Protects Against Brain Damage and Improves Learning and Memory
After Traumatic Brain Injury in Adult Mice. Cereb Cortex, 2018. 28(8): p. 2854-2872.
12- SA Shah, FU Amin, M Khan, MN Abid, SU Rehman, TH Kim, MW Kim. Anthocyanins
abrogate glutamate-induced AMPK activation, oxidative stress, neuroinflammation, and
neurodegeneration in postnatal rat brain. J Neuroinflammation, 2016. 13(1): p. 286.
13- SA Shah, GH Yoon, SS Chung, MN Abid, TH Kim, HY Lee, MO Kim Novel osmotin
inhibits SREBP2 via the AdipoR1/AMPK/SIRT1 pathway to improve Alzheimer's
disease neuropathological deficits. Mol Psychiatry, 2017. 22(3): p. 407-416.
14- Noman Bin Abid. Hussain R, Yasmin N, Zafar T, Iqbal S, Niazi GA. Identification of
Factor VIII gene mutations in Hemophilia A patients from Punjab. World J Med Sci 2007,
2: 25-27.
15- SA Shah, GH Yoon, SS Chung, MN Abid, TH Kim, HY Lee, MO Kim, Osmotin reduced
amyloid beta (Aβ) burden by inhibiting SREBP2 expression in APP/PS1 mice Molecular
psychiatry 22 (3), 323
16- Muhammad Imran, Saqib Mahmood, Rashid Hussain, Noman Bin Abid, Khalid P Lone.
Ethnic and geographic distribution of PRNP polymorphisms in the Pakistani population.
Gene 2012, 1:186-194 .
17- Imran M, Mahmeed S, Babar ME, Hussain R, Yousaf MZ, Noman Bin Abid, Lobe KP.
PRNP gene variation in Pakistani cattle and buffaloes. Gene 2012 15;505(1):180-5.
18- Rashid Hussain, Noman Bin Abid, Sajjad Hussain, Zeeshan Shaukat, Sara Altaf, Gulzar
Niazi. Three Novel Mutations in sporadic haemophilia A cases. Springerplus 2012 (1)
1:10

Conference Proceedings:

• Noman Bin Abid, Haroon Badshah, Gwanghoo yoon, Imran Naseer, Myeong Ok Kim.
“Molecular cloning and High Throughput production and Purification of Osmotin by
Baculovirus-insect cell system”. Poster presented at 3rd IGMC, CEGMR , King Abdul
Aziz University, Jeddah Saudi Arabia, 2015.
• Noman Bin Abid, Imran Naseer, Myeong Ok Kim. “Baculovirus mediated gene delivery
as a tool for gene therapeutics of neurodegenerative diseases. 3rd IGMC, CEGMR , King
Aldul Aziz university , Jeddah SaudiArabia. 2015.
• Noman Bin Abid, Muhammad Tariq. “Establishing Microinjection facility at LUMS to
generate transgenic flies.” Presented at Research symposium 2013 at Lahore University of
Management Sciences Lahore.
• Noman bin Abid, Saima Anwar, Shazia Rafiq, Usman Rashid, Sohail Qureshi, Muhammad
Tariq, “Identification of DNA Methylation Profiles in Cancer”. Poster presented at
Research Expo. 2011 held at Lahore University of Management Sciences.

Awards and Distinction:

• BK-21 Korean Government Scholarship for PhD


• Young Pioneer’s award for excellence in research 2017
• Young Pioneer’s award for excellence in research 2018

Teaching experience:

• Assistant Professor (Visiting Faculty): (April 2021 - Sept 2021.)


Dept of Applied Life Sciences, Khawaja Fareed University of Engineering and
Information Technology.
Courses taught:
Animal Diversity, Biochemistry, Cell Biology, Genetics and Evolution
• Lecturer Superior College (R.Y.Khan Campus): (Oct 2020-March 2021)
Courses taught:
Biology and Zoology
• Head of Biology/Zoology Department NICAAS College RYK (2013-2014)
Courses taught:
Biology, Zoology, Environmental Biology, Genetics, biostatistics
• Teaching Assistant: (Sep 2008 – Dec 2009)
School of Science and Engineering. LUMS. Lahore, Pakistan.
Courses taught:
Bio 101; Freshmen Bio Lab 100; Drosophila Fly lab modules

Skills and Techniques:

• Molecular Techniques: DNA extraction (blood and tissue), RNA isolation (blood,
tissue and serum), Protein extraction (tissue), Gel Electrophoresis (PAGE and Agarose),
SDS-PAGE, PCR, RT-PCR, Molecular cloning, Plasmid isolation, Western Blot, DNA
Sequencing, HCV genotyping, Protein binding assay.
• Cell culture Techniques: Cell line culturing, Media preparation, Transfection,
Transformation, protein extraction from cells,
• Drosophila Lab Skills: Fly Pushing, Imaginal discs dissections, and Staining, Mitotic
clones, Bi Sulphite sequencing, ChIP. Transgenic flies by microinjection.
References:

• Dr. Hiroko Yano


Associate Professor of Neurosurgery, Neurology, and Genetics.
Department of Neurosurgery. School of Medicine. Washington University in St. Louis.
Ph: +1 3147476012
Email: yanoh@wustl.edu
• Dr. Myeong Ok Kim
Associate Professor. Division of Life Sciences and Applied Life Science (BK 21plus),
College of Natural Sciences, Gyeongsang National University, Jinju, 52828, Republic of
Korea.
Email: mokim@gnu.ac.kr
• Dr. Keun Woo Lee
Research Institute of Natural Science (RINS), Gyeongsang National University (GNU),
501 Jinju-daero, Jinju 52828, Republic of Korea
Ph: +82 1028046030
Email: kwlee@gnu.ac.kr
• Dr. Muhammad Tariq
Associate Professor. Biology Department. SBA School of Science and Engineering,
LUMS, Lahore.
Ph: +92 308444627
Email: m.tariq@lums.edu.pk
• Dr. Muhammad Imran Naseer
Associate Professor. Center of Excellence in Genomic medicine research,
King Abdul Aziz University, Jeddah Saudi Arabia.
Ph: + 96 626401000
Email: minaseer@kau.edu.sa

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