Parathyroid Hormone

You might also like

Download as docx, pdf, or txt
Download as docx, pdf, or txt
You are on page 1of 1

The image shows the Parathyroid Hyperplasia in all cells in each parathyroid gland.

We can see that


each gland is growing at a different rate, thus all hyperplastic parathyroid glands are a different size.
These four parathyroid glands lie immediately behind the thyroid gland. Almost all of the parathyroid
hormone is synthesized and secreted by the chief cells – which is the primary cell of the parathyroid
gland.

The parathyroid gland contains mainly chief cells and a small to moderate number of oxyphil cells. The
chief cells are believed to secrete most, if not all, of the PTH. The function of the oxyphil cells is not
certain, but they are believed to be modified or depleted chief cells that no longer secrete hormone.

the chief cells (zymogenic) are basophilic cells that are located in the bottom of the gland and which
produce different gastric enzyme precursors, such as pepsinogen.

The secretion of parathyroid hormone (PTH) is regulated by the interaction of the calcium-sensing
receptor with calcium in the blood. The calcium-sensing receptor is present on the plasma membrane
of the chief cells. The CaR is a G protein-coupled receptor, as part of the C family.

You might also like