6434119923 อ ญญา ต รม

Proteins

· Problem 24 - 4

Drow the structure of predominant form.

(b) proline at et 2

(a) giolomic osid at

gl

% 1
b) ↑ a.
·H
↓
-

-
+

NH 2
NH2

· croblem 24.8 กลาง

this
·
prow the
electrophoretic separation of
top, lys and at
9 4 ...

ร
-> :บwen ·

-
cothode

# !
·
A

>
node
+

His Tri

· Problem. ชม so
24

to the amino acids

world - see bromination on synthesize following
b) Leucine " เก

" , ONOffrecess
NH
! 2

·H
/ ·
1.
Bru ( NHat
2.128
!
!

eleusines

I mo -
!"2

whitegerne
small
1
:0 with

· Iroblems 24- 11
show how the Gabriel - molonic ester synthesis could be used to moke.
COOH

า
↓ Leucine ·
เห อน าน าง
MSN - ·แ
door
"กร "
·
-

/ NH, +
t

~My
9005t
A
↳
1. NG - sot ↑ / +
/
N. 3 H
>
/ >
"
~ OH
↳อย :
/OH

↓อ
bookt 2 /I
/ boost ↳
-

Levine
Hydrolysis
ภิ
ทั
ปี
ด้
ว่
มื
ย์
ต่
ล่
นั
 ·· Problem 24- 93

show strecker synthesis to make

12) how
you would use a
phenylelanine

%
↑ -I was a
retreation , M10 = ((
i mi ne

-
* "( "
↳ C- H &
/ /
-
=Ni โ

#" (protonation (

:fro
NH2

-4
H20
> 2
↑
/
=N - H

good. "· #
1- WHI
Hot !NI

1 to
I heny salon

·· Problem 24- 20

Draw the of peptides.

complete structures
following

2) Thr- the- Met

:

NH
s

N If
%
:ร
- Ol

·
/
·

S
ที
ญี
มี
 · Problem 24- 31

show how solid- phase peptide synthesis would used to make tle -
Gly - Asn

encm2 8
( * HIN- CH COOH 3
2 - NH- CH - - OH

benzy) chloroformote) CHIC ACH2 CHs Color CHI CHa

iso leucine

11 - 0 out
/
/

3- 3- Bet
SM-
2 - NM - 0 -

CH3 HCH, CH3

HINCH COON ( glycines

a

2- NH - -NH -
pH
CH - อะ

/ #
CHs CH CH2C If
y

กร
C1- - OEt

2- NH - -NH B- Out

pH
CH-

/ #

CHs CH CH2C If
y

. MEN- Acor losporogines

NROMDM- PM - NM-coNPC
2-

d
~2 19

HONDA SM- PM - NM-coNPC

ปี
ปี
 Corbohydrates
·· Problem 23- 8

Drew
3) D- teclose, the is eximer of O-
golactose
แห ง 2

C2 Prime
'CH8
r

CHO

/ /
1
2
8 H
8 If I

H0 H H0 H
4
4

HO H

40 ↓
H
5
⑧(

" CH 2 8 H
" CH 2 8 H

0-
golactose &- tolo 59

· Problem 23 - 9

for
Brow the Howorth projection the cyclic structure of D- monnose
by loying down the
fisher projection
a, f

CH O

ร "transfer +
HO H 6
6

2&H
6
H
C H C H 2&H
#
.H
ป
+20 rotated th

"/ "!
5
=

1
* M
H ①OH
H
ขา ↑
uf · >
/

40 "
>

·ก QH
/

notin
4

H ⑧H not not H
5
H 8 I

เ &-D- monnose

CH20H 6
C H 2&H

Qi
1- mshmose "

40 หมก
2 - D- monnose

· Iroblem 25- 10

Allose the primer of Droiw the cyclic hemincetal form of D- ollose, first in the
is is glucose.
chair conformation and then in the Haworth projection

1
CH8

2
H 8I ⑥M ,

~And
0'
·

H
3
8H 18
↑ 4 /
4
>
↓H &

"ไ
#

H 8M !
.H
5 |0
H ⑧If
a - D- ollose
&H 8H

6
24
201 chair conformation Horworth
projection
เ
A llost
↑
↳****
not
in a

!"M
!
3

H/ You
&H
8 - D-
dre
3
allOSG
·
ตำ
ที่
น่
· Problem 23.21

brow and name the products of bromine water oxidation of

(b) D- golactose
, CM 8 :900 H

H H
olf olf
S
1) Br2 S
↑ H > HO H

4 H 20
2)
4

170 H 170 H

5 5
H Of H Of

เ เ

CH20H CH20H

o- Galactomic acid
geroctose

· problem 23- 22

Draw and name the products of Nitric acid oxidation of

(b) O-
golactose

, CM 8
COOH
1

H
olf H
olf
S #NO3 S
↑O H > ↑O H
4
4
170 H
170 H
5
5
H Of H Of

CH20H "COOH

&- golactose Golactric acid

· froblem 23- 25

Two A and 8, known to but it not certain which

sugars, are be
glucose and golactose is one is

which on treatment with hitric acid, A

gives on
optically inoctive olderic acid, while i gives an obtically active
chirel
Olderic acid, which sugar is glucose, and which is
galactose?

, CM 8
COOH , CM 8
COOH
1 1

H
olf H
olf
H ·H
H
olf
S #NO3 #NO3

10 -
↑ H
S 1 S
> ↑ H > ↑ H
4

170 H
4
In d If ⑧H 4

170 H H 0H
5 5
5 5
H Of H Of H Of H Of

เ เ

"COOH
เ
CH20H CH20H 200H

A Golactric acid 3 อานา Gris GCid

p-
golactose A-
glucose
active
optically in active obtically
achiral) chira.

Sugar A is gelatose
is
Sugar a
งาน 38SG
·· Problem 23- 30

Draw product of the of with and silver oxide

the expected reaction the following sugars methyl iodide

b) 8- D-
golactopyronose

G OCH3
CHION 1 ·
CH20MCH3

"ไท
~
/
excess ( H 3 "

/OM
>

Coins
"

-OCH
:'
A 9
0
H

8- o-
golactory ronose