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SCIENTIFIC ARTICLE

Semiconstrained Total Elbow Arthroplasty for


Posttraumatic Arthritis or Deformities of the Elbow:
A Prospective Study
Izaäk F. Kodde, MD, Roger P. van Riet, MD, PhD, Denise Eygendaal, MD, PhD

Purpose To report the short-term results for posttraumatic total elbow arthroplasty.
Methods We included patients presenting to our hospital with symptomatic chronic posttrau-
matic arthritis or deformities of the elbow, aged 55 to 90 years. All patients had reconstruc-
tion with a Coonrad-Morrey prosthesis. We performed clinical follow-up after 2, 6, 12, 24,
and 36 months, consisting of physical examination, standard radiographs, and calculation of
the Mayo elbow performance index.
Results A total of 17 patients were enrolled in this study and had a mean follow-up of 32
months. Mean preoperative flexion arc was 67° and 105° postoperatively. The mean
preoperative Mayo elbow performance index score was 54 (range, 30 – 80) and improved to
a postoperative score of 93 (range, 60 –100). We encountered 6 complications in 5 patients.
Four complications required surgical intervention and 2 minor complications were treated
noninvasively.
Conclusions Short-term functional outcomes after total elbow arthroplasty in this prospective
cohort of patients with posttraumatic arthritis or deformities of the elbow were good
according to mean postoperative measurements. (J Hand Surg 2013;38A:1377–1382. Copy-
right © 2013 by the American Society for Surgery of the Hand. All rights reserved.)
Level of evidence/type of study Therapeutic IV.
Key words Elbow, functional outcome, posttraumatic, total elbow arthroplasty.

T
HE ELBOW IS INVOLVED IN 7% of all adult frac- failure, and/or posttraumatic osteoarthritis are reported
tures, and it is predicted that the number of in up to 20% of cases.3,4
fractures of the distal humerus in the elderly The sequelae of these complications and of posttrau-
will increase.1,2 The reference standard for the treat- matic elbow arthritis can be treated by arthrodesis,
ment of fractures of the distal humerus is open reduc- interposition arthroplasty, or total elbow arthroplasty
tion and internal fixation (ORIF). Despite advances in (TEA). Generally, arthrodesis of the elbow relieves pain
elbow fracture fixation systems, the complication rates and restores strength, but it is accompanied by a major
remain high because malunion, nonunion, hardware functional impairment. Interposition arthroplasty re-
lieves pain as well and improves motion, but results are
From the Department of Orthopaedics, Upper Limb Unit, Amphia Hospital, Breda, The Netherlands;
and the Department of Orthopaedics and Traumatology, Monica Hospital, Deurne, Belgium. unpredictable. Persistent instability is often found,
Received for publication January 28, 2012; accepted in revised form March 26, 2013. which results in poor functional outcomes.5–7 Good
No benefits in any form have been received or will be received related directly or indirectly to the
results of TEA for a broad variety of chronic posttrau-
subject of this article. matic elbow disorders are reported in numerous retro-
Corresponding author: Izaäk F. Kodde, MD, Department of Orthopaedics, Amphia Hospital, spective studies.8 –17
Post-box 90158, 4800 RK Breda, The Netherlands; e-mail: if.kodde@hotmail.com. However, most reports on TEA for posttraumatic
0363-5023/13/38A07-0014$36.00/0 conditions originate from authors who were involved in
http://dx.doi.org/10.1016/j.jhsa.2013.03.051
the design of the implant, and a systematic review by

©  ASSH 䉬 Published by Elsevier, Inc. All rights reserved. 䉬 1377


1378 TEA IN POSTTRAUMATIC ELBOW ARTHRITIS

Voloshin et al18 revealed complications in 38% of wear was recognized as an asymmetric angle of more
TEAs placed for posttraumatic sequelae. These high than 7° of the CM implant at the bearing surface, as a
complication rates and concerns about the implant du- result of deterioration of the ulnohumeral polyethylene-
rability in this population have limited the widespread bearing surface.20 Radiolucent lines were classified and
use of TEA for posttraumatic disorders. subdivided into 5 types: type 0, no radiolucent lines or
The purpose of this study was to prospectively eval- lines involving less than 1 mm and less than 50% of
uate the complication rate and effect of complications interface; type 1, lines involving greater than 1 mm and
on the early functional outcome of the Coonrad-Morrey less than 50% of interface; type 2, lines involving
(CM) TEA (Zimmer, Warsaw, IN) for chronic posttrau- greater than 1 mm and greater than 50% of interface;
matic elbow arthritis. type 3, lines involving greater than 2 mm and complete
interface; and type 4, clear radiographic signs of loos-
PATIENTS AND METHODS ening, such as shifting of the components.13
We designed a prospective cohort study to evaluate
clinical results of the CM TEA for symptomatic post- Surgical technique
traumatic arthritis or deformities. Chronic conditions We administered prophylactic antibiotics (1,000 mg
such as nonunion, malunion, persistent dislocation, cephazolin intravenously) 30 minutes preoperatively.
and/or painful arthritis of the elbow were included. We We made a posterior midline skin incision and used a
treated 17 consecutive patients (ages 55– 82 y; 4 men triceps-splitting approach. The ulnar nerve was identi-
and 13 women) between 2006 and 2011. Patients with fied, released, not transposed, and protected throughout
nontraumatic degenerative changes, acute elbow the procedure. We identified the medial and lateral
trauma, active infection or history of deep infection, collateral ligaments when possible and released them at
poor compliance with regard to after-treatment, or up- their humeral attachments. The distal humerus and
per extremity paralysis, and patients with a nonrestor- proximal ulna were prepared for a CM prosthesis. We
able triceps function were excluded from the study. We implanted prostheses using tobramycin-impregnated
obtained informed consent from all patients. Exemption bone cement (Simplex Bone Cement Powder; Stryker,
of institutional review board approval was granted, be- Hamilton, Ontario, Canada). Postoperatively, antibiot-
cause the protocol used in this study is the current ics were continued for 48 hours, and oral meloxicam
standard of care in our hospital. was routinely prescribed for 1 week.
All patients underwent a preoperative clinical assess- The elbow was placed in 90° flexion with neural
ment by the surgeon, consisting of range of motion rotation in a plaster splint. After 48 hours, a removable
(ROM), assessment of stability, and calculation of the splint was applied in 30° flexion and physical therapy
Mayo elbow performance index (MEPI). The MEPI is was started. During the first 6 weeks, active extension
based on 4 items (pain, range of motion, stability, and was avoided. Patients were advised to not lift objects
elbow function). A total score between 95 and the over 5 kg.
maximum 100 points is considered excellent; 80 to 94 We performed statistical analysis using paired t-test,
is good; 60 to 79 is fair, and less than 60 points is poor. sign test, and Wilcoxon signed-ranks test to compare
We obtained standard calibrated radiographs (antero- preoperative and postoperative changes in numerical
posterior and lateral) of the elbow before surgery. A data. We used the independent t-test to compare numer-
single surgeon (D.E.) performed all procedures. ical data between groups of patients in this cohort.
Postoperative clinical evaluation by an orthopedic Results were considered statistically significant at
nurse practitioner took place at 8 weeks, 6 months, and P ⬍ .05.
1, 2, 3, and 4 years, and consisted of range of motion,
strength, stability, neurological status, and standard an-
RESULTS
teroposterior and lateral radiographs. The MEPI ques-
tionnaire was completed. Radiographs were assessed Initial clinical data
for periprosthetic fractures, heterotopic ossifications, A total of 17 patients with a minimum follow-up of 12
bushing wear, and radiolucent lines. We classified het- months were enrolled in the study. One patient died 4
erotopic ossification according to Hastings and Gra- years after surgery of causes unrelated to the TEA.
ham.19 Class I lesions are subclinical. Class IIA lesions There was no further loss to follow-up. The average age
limit flexion-extension. Class IIB lesions limit prona- of patients at time of surgery was 70 years (range,
tion-supination. Class IIC lesions limit motion in both 55– 82 y). The dominant elbow was affected in 47% of
planes. Class III describes complete ankylosis. Bushing patients. Mean time of follow-up was 32 months (range,

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TEA IN POSTTRAUMATIC ELBOW ARTHRITIS 1379

TABLE 1. Comparison of Elbow Function, Heterotopic Ossifications, Complications, and MEPI Score
Between Patients With and Without Previous Operations
Patients Preoperative Postoperative Preoperative Postoperative Heterotopic
(%) FE FE Prosup Prosup Ossification Complications MEPI

Previous 14 (82%) 74° 107° 114° 134° 6 4 93


operation
No previous 3 (18%) 35° 93° 113° 90° 2 1 97
operation

FE, flexion-extension arc; Prosup, prosupination arc.

TABLE 2. Preoperative and Postoperative Range of Motion


Flexion Extension Flexion Arc Pronation Supination Prosupination Arc

Preoperative 100 33 67 57 57 114


Postoperative 126 21 105 66 60 126
P value .001 .112 .002 .076 .579 .215

12– 69 mo), and the average time from injury to surgery Radiographic outcome
was 100 months (range, 2 mo to 56 y). At the latest follow-up, we found signs of hetero-
There was severe posttraumatic arthritis of the elbow topic ossifications in 8 patients (47%), 7 of whom
joint in 11 patients. Four patients had a malunion after were classified as Hastings and Graham class I and
an intra-articular fracture of the distal humerus, 1 had 1 of whom was classified as class IIA. We saw
nonunion after an intra-articular fracture of the distal radiolucent lines on the radiographs of 4 patients,
humerus, and 1 had nonunion of an extra-articular frac- 1 of whom was graded as type 1 and 3 of whom
ture of the distal humerus. These injuries also resulted were type 4. One patient had a loose humeral
in 2 flail elbows, 1 ankylosis, and 1 ulnar nerve dys- component after a deep infection, 1 had a loose
function. Initial injuries included 1 or more fractures in humeral component after a fall on the arm with a
16 patients, consisting of humerus fractures in 10 pa- subsequent periprosthetic fracture, and another pa-
tients, radius fractures in 6, and ulna fractures in 3. Six tient had aseptic loosening of the ulnar component.
of these had fracture-dislocations. One patient had post- There were no signs of bushing wear in any of
traumatic arthritis resulting from a chronic posterolat- these patients at latest follow-up. Figures 1 and 2
eral dislocation. show an example of failed ORIF followed by TEA.
A total of 14 patients (82%) had previous surgery on
the elbow before implantation of the TEA. Previous Complications
surgery consisted of ORIF in 9 patients, radial head In 5 patients (29%) there were a total of 6 complica-
resection in 2 patients, implantation of a radial head tions. These complications consisted of 2 minor com-
prosthesis in 2 patients, and a medial epicondyle resec- plications not requiring reoperation and 4 major com-
tion in 1 patient. Table 1 compares the groups of pa- plications requiring surgical management. We found
tients with and without previous surgery on the elbow. severe stiffness in 1 patient. Arc of motion improved
from 30° to 80° with intensive physiotherapy and use of
Functional outcome a continuous passive motion machine. The other minor
The mean preoperative MEPI score was 54 (range, complication was a superficial skin infection that re-
30 – 80) and improved to a postoperative score of 93 solved within a week using oral antibiotics.
(range, 60 –100) (P ⬍ .001). One patient had a fair With regard to the major complications, 1 patient
result; the other 16 (94%) had a good or excellent MEPI had persisting ulnar nerve dysesthesia, which resolved
score. Table 2 lists preoperative and postoperative mo- after an ulnar nerve decompression. Three patients had
tions. loosening of a prosthetic component, as described in the

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1380 TEA IN POSTTRAUMATIC ELBOW ARTHRITIS

FIGURE 1: Example of unsuccessful ORIF. This patient had ORIF after a fracture of the distal humerus and subsequently a
second operation with autologous bone substitution and new fixation after an olecranon osteotomy because of a nonunion.
A Anteroposterior view. B Lateral view.

FIGURE 2: The same elbow after removal of hardware during a first operation and implantation of a Coonrad-Morrey prosthesis
during a second operation. A Anteroposterior view. B Lateral view.

section on radiographic outcome. The patient with a maintained. The patient with a deep infection developed a
periprosthetic fracture was treated with a plate osteosyn- chronic draining synovio-cutaneous fistula but accepted
thesis of the humerus, while the humeral component was this situation and refused further surgical intervention. The

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TEA IN POSTTRAUMATIC ELBOW ARTHRITIS 1381

patient with aseptic loosening has been scheduled for a TABLE 3. Comparison of Complications Between
revision of the loose implant. This Study and the Literature, According to the
Final MEPI scores were 83 for the 5 patients with Systematic Review by Voloshin et al18
complications, compared with 98 for patients without
complications (P ⫽ .09). The ROM was 87°, compared This study, no. Literature,
Complication (%) %
with 112° in favor of patients without complications
(P ⫽ .05). Deep infection (and loosening 1 (6) 3
component)

DISCUSSION Superficial infection 1 (6) *


Aseptic loosening component 1 (6) 14
The results of TEA for posttraumatic elbow disorders
Periprosthetic fracture (and 1 (6) 2
have been reported to be good in most retrospective
loosening component)
studies.8 –17 In this prospective study, functional out-
Ulnar nerve dysesthesia 1 (6) 3
comes after TEA in patients with posttraumatic arthritis (without nerve
or deformities of the elbow were good according to the transposition)
mean postoperative MEPI score (93). One patient Limited range of motion 1 (6) *
with loosening of the humeral component and a Triceps tendon dissection 0 2
malunion of the humerus after a traumatic (triceps split approach)
periprosthetic fracture had a fair result. These re- Overall 6 (35) 38
sults are slightly better than results reported by
others (64% to 83% of patients with a good or *No information in systematic review.
excellent result and mean MEPI scores of 75– 82
points for posttraumatic prosthesis place-
ment).8,13,15,17,21 However, some of these studies al23 reported on 10 patients who had a CM revision
were based on earlier generations of implants or had because of bushing wear or C-ring failure after an
a longer patient follow-up and therefore reported average of 60 months (range, 9 mo to 12 y).23 In the
more implant-related complications.17,20 current study, there were no radiographic signs of bush-
There were 14 patients (82%) with previous surgery ing wear at follow-up, although 1 case of early aseptic
on the elbow, which is similar to 90% in a series by loosening occurred.
Throckmorton et al.17 Prior surgery increases perioper- Complication rates after TEA are higher than those
ative risks because of possible altered anatomy, loss of after replacement surgery of other large joints.24 Until
bone stock, heterotopic ossification, wound problems, 1993, the complication rate after TEA was up to 43%,
and infections. In the current study, there were no decreasing to 22% to 38% in recent literature, according
significant differences in motion, MEPI scores, and to a systematic review by Voloshin and colleagues.18
complications between patients with and without pre- They found a complication rate of 38% for posttrau-
vious operations. However, this comparison is under- matic TEA, compared with 22% and 24% for TEA in
powered, because there were only 3 patients without acute distal humerus fractures and rheumatoid arthritis,
prior surgery. respectively, with a significant difference between the
The semiconstrained linked design of the CM pros- acute fractures and chronic posttraumatic arthritis. The
thesis is well suited for posttraumatic reconstruction most frequent reported complications were aseptic
because its function does not depend on the integrity of component loosening (5% based on clinical examina-
the epicondyles, collateral ligaments, or radial head. tion; 14% based on clinical examination and radio-
This may account for the relatively good results in our graphic radiolucency), instability (5%), and deep infec-
cohort. However, it has also been suggested that this tion (3%). There were significantly fewer reports of
design may be at risk for early bushing wear in this instability in patients who had a linked device18; how-
population.22 Cil et al22 observed evident bushing wear ever, this may be at the cost of component loosening. In
in all 5 study patients who had deficiency of the epi- our series, there were 3 patients with component loos-
condyles and were aged younger than 65 years, within ening. A deep infection occurred in 1 patient. These
5 years.22 This phenomenon can be explained by the results are in accord with the numbers of Voloshin et al
fact that the increased constraint offered by a linked (Table 3). The minor complications (limitation of mo-
design places greater stress on the bushing and implant– tion and superficial skin infection) we report are not
bone interfaces, which may lead to increased rates of described in their systematic review. With inclusion of
bushing wear and/or component loosening. Wright et these minor complications, our overall complication

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1382 TEA IN POSTTRAUMATIC ELBOW ARTHRITIS

rate of 35% is comparable to other studies. However, if 7. McAuliffe JA, Burkhalter WE, Ouellette EA, Carneiro RS. Com-
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This study is limited by the short-term follow-up. In Functional outcome of semiconstrained total elbow arthroplasty.
particular, implant-related complications may be under- J Bone Joint Surg Am. 2000;82(10):1379 –1386.
9. Inglis AE, Inglis AE, Jr., Figgie MM, Asnis L. Total elbow arthro-
rated because complications tend to occur with time. plasty for flail and unstable elbows. J Shoulder Elbow Surg. 1997;
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North Am. 1999;30(1):141–162.
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tients included in this cohort. Further prospective stud- ankylosed and stiff elbows. J Bone Joint Surg Am. 2000;82(9):1260 –
ies based on larger groups of patients are needed to 1268.
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bow replacement for primary and revision surgery: a 2- to 7.5-year
postoperative MEPI score of 93. Despite the advances
follow-up study. J Shoulder Elbow Surg. 2007;16(3 Suppl):S47–
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current study remains high. Although the differences 17. Throckmorton T, Zarkadas P, Sanchez-Sotelo J, Morrey B. Failure
were not significant, there is a tendency for these com- patterns after linked semiconstrained total elbow arthroplasty for
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in these patients. In general, TEA can still be considered 18. Voloshin I, Schippert DW, Kakar S, Kaye EK, Morrey BF. Com-
as the salvage procedure of choice for posttraumatic plications of total elbow replacement: a systematic review. J Shoul-
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