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Reconstruction Options and Outcomes For Acetabular Bone Loss in Revision Hip Arthroplasty
Reconstruction Options and Outcomes For Acetabular Bone Loss in Revision Hip Arthroplasty
deficiency. The major flaw of this classifi- teardrop and severe lysis of the ischium hemipelvis, resulting from bone loss or
cation system is that it does not address the with a superomedial migration (known as fracture of the acetabulum. In addition to
management of these defects (Table 1). “up-and-in” deformity). Patients with type providing a system for describing bone loss,
The Paprosky classification was intro- IIIB defect have a high risk of pelvic dis- the Paprosky classification also guides
duced in the early 1990’s (Table 1). This continuity (PD), defined as the loss of con- treatment strategy (Figure 1).
classification system relies on preoperative tinuity between the superior and the inferior
and intraoperative evaluation and it is based
on the presence or absence of and intact
acetabular rim and its ability to provide ini-
tial rigid support for an implanted acetabu-
lar component. The hip center migration
and the integrity of four acetabular support-
ive structures are evaluated on preoperative
antero-posterior (AP) radiograph of the
pelvis: the teardrop (medial wall), the hip
center (superior dome), the Kohler’s line
(anterior column) and the ischium (posteri-
or column). Type I defects have minimal
focal bone loss, the hemispheric shape of
the acetabulum is maintained with neither
periprosthetic osteolysis nor migration of
the components. Type II defects show a dis-
tortion of the acetabular shape; anterior and
posterior columns are still present but is
evident a deficit of the superior dome
and/or the medial wall. This category is
subclassified in IIA, with an ovalized
acetabulum, superior lysis with a <2cm
superior migration but an intact superior
rim; IIB, similarly to the IIA but with a defi-
cient superior rim so the implants migrates
superolaterally; and IIC, where the implant
may migrate medially due to a deficient
medial wall. Type III defects involve major
bone loss with >3cm migration of the
implant, destruction of the acetabular rim
and supportive structures. If the acetabulum
is considered as a circular structure inter-
preted like a clock face, the IIIA pattern
extends from ten o’clock to two o’clock
(30% to 60% of bone stock destruction)
with an intact Kohler’s line (medial wall)
and ischium and a superolateral migration
(known as “up-and-out” deformity). The
IIIB defines a major bone loss from nine
o’clock to five o’clock (>60% of the bone
stock) that involves both walls and both
Figure 1. Algorithmic approach to acetabular reconstruction (Redrawn from Sporer SM,
Paprosky WG, O’Rourke MR: Managing bone loss in acetabular revision. Instr Course
columns with severe obliteration of the
Lect 55:290, 2006.).
cal technique familiar to many arthroplasty implant contact.51 The main advantage of Cup + “footing” augment: in massive
surgeons; however, it is accepted that pro- the cups is their relative ease of implanta- medial cavitary or segmental defects to sup-
vide poor results in severe acetabular bone tion and the oblong shape that almost port the cup (Paprosky type IIIB).
defects (>50% of bone stock).51 enables a press-fit incorporation. All the junctions between tantalum
components need to be filled with cement,
Extra-Large “Jumbo” Cups Modular Porous Metal Augments except for the “footing” conformation. The
Extra-large “jumbo” cups are an option Porous modular metal augments in con- remaining cavitary defects are filled with
in case of major defects (Paprosky Types II junction with highly porous cup represent a cancellous bone chips.48
and III; AAOS Types 3 and 4). They are viable option for the reconstruction of mod- In case of severe medial bone defects
defined as having a diameter >66mm in erate-to-severe acetabular bone defects (Paprosky Types IIC, IIIA and IIIB),
males and >62mm in females, approximate- (Paprosky Types IIIA, IIIB and pelvic dis- Blumenfeld et al,67 described the “cup-in-
ly 10mm larger than the mean diameter of continuity).62-64 Porous metal augments are cup” technique with ah highly porous
the acetabular components used in primary made with highly porous tantalum or titani- “Jumbo” cup combined with cementation of
THA.52 This technique has multiple advan- um. The higher porosity (up to 80%) allows a similar highly porous cup into the initial
tages: it is technically straightforward, most a proportionate increase in interface jumbo cup. Webb et al,68 described the
bone defects are filled by the socket itself strength compared to conventional implants “double-cup” technique (Paprosky type
obviating the need for extensive bone-graft, and the high coefficient of friction improves IIIA, IIIB) using a highly porous cup as a
there is an increased contact area between the primary stability.2,63 Highly porous cups, “super-augment” to buttress the superior
the implant and the host bone and the center usually used alone in mild-to-moderate medial or lateral defect.
of hip rotation is translated to a more lateral bone defects (Paprosky Types I and II), can In a recent systematic review, Baauw et
and inferior position.11,52-54 Disadvantages be supported with porous metal augments al,3 reported on the use of porous metal aug-
are that a large socket limit the bone stock and/or cage when bone loss is >50% of the ments in large acetabular defects (Paprosky
restoration in case of additional re-revision original bone stock or in presence of pelvic
of the acetabular component, and large, Types IIIA and IIIB; AAOS Types 3 and 4).
discontinuity.48,62 Highly porous revision They found a survivorship from re-revision
oblong bone defects cannot be filled in an shells have a multi-hole configuration (8-12
inferior-to-superior direction without of 98.4% (2 of 125 hips), a radiographic
screw holes) in order to position additional loosening of 2.4% (3 of 125 hips), an over-
marked reaming of the anterior or posterior screws and increase stability.2 Highly
column (vital for the implant fixation) or all reoperation rate of 15.2% (19 of 125
porous augments are usually fixed to the hips) and a dislocation rate of 4.8% (10 of
superior placement of the cup.52 Relative bone before the fixation of the acetabular
contraindication are previous irradiation of 125 hips) at mean follow-up of 3.8 years.
cup in case of large intracavitary defects
the pelvis and massive acetabular bone loss (anterosuperior and posteroinferior). In case Cup-Cage Reconstruction Systems
of the superior-lateral rim or the posterior of extracavitary defects (posterosuperior) Cup-cage reconstruction is indicated in
column that can preclude the initial implant the augments can be positioned after the case of severe bone defects (Paprosky Type
stability.2,52 Von Roth et al,53 reported a sur- acetabular cups since they provide a supple- III) and chronic pelvic discontinuity.
vivorship of 83% (15 of 89 hips) at 20 mental fixation.14 The use of metallic mate- Described by Nehme et al,64 it is a hybrid
years. In a recent systematic review Volpin rial, instead of bone grafts, avoid certain technique based on a highly porous cup
et al,11 reported a failure rate of 12.1% (63 risks associated with allografting like trans- with partial press-fit in combination with
of 518 hips) at 10 years, with liner exchange mission of infections, variable mechanical morselized host-bone or allograft, support-
as the most common causes of reoperation characteristics and partial resorption or ed by a cage that provides load relief. The
(7.1%). healing; on the other hand it is necessary to liner is then cemented into the cage and the
Oblong Cups remove some extra host bone to accommo- hip center is brought back to a more physi-
Oblong cups are indicated in large supe- date the metallic augment and achieve the ologic position. Once the cup is well inte-
rior segmental bone defects with a prevalent indispensable press-fit.3,47 For the majority grated the cage is offloaded preventing
superior migration and a longitudinal diam- of the porous metal augment systems avail- mechanical loosening.69 Early outcomes
eters that are greater than their transverse able in the market, the junctions between reported a survivorship of more than
diameters (Paprosky Types IIA, IIB and the porous metal augments and the highly 85%,70,71 and encouraging mid-term clinical
IIIA).55,56 Oblongs cups adapt better to large porous cups need to be filled with cement, and radiological outcomes have been
and oblong bone defects, that cannot be to avoid the release of metal fragments and reported in case of pelvic discontinu-
filled with hemispherical cups, avoiding induced metallosis.47,65 Jenkins et al,66 ity.69,72,73 Abolghasemian et al,69 reported a
marked reaming of the anterior and posteri- reported a survivorship from aseptic loosen- survivorship of 88.5% at a mean 3.9 years
or columns.51,55-61 Three types of Oblong ing of 97% (2 out of 58 hips) for aseptic (3 of 26 hips); Martin et al,73 reported a sur-
Cups have been described: the bilobed loosening at a minimum 5-year follow-up vivorship of 100% in a cohort of 27 hips at
oblong acetabular component, the longitu- and proposed variable configurations in 5 years with 74% of healing of the disconti-
dinal oblong revision cup (LOR) and the order to achieve stability in different bone nuity; Amenabar et al,72 reported an overall
BOFOR cup.56 In a recent systematic defects: survivorship of 91% (4 of 45 hips) at a
review, Volpin et al,11 reported good results Cup + “flying buttress” augment con- mean follow-up of 6.4 years when cup-cage
for oblong cups in term of overall failure figuration: in peripheral segmental defect, constructs were used for the treatment of
rate (5.9%, 12 of 203 hips) with an aseptic particularly in the posterosuperior quadrant pelvic discontinuity. Concerns are
loosening rate of 3.9% (8 of 203 hips) and a (Paprosky type IIIA). addressed regarding the positioning of the
dislocation rate of 2.4% (5 of 203 hips) at a Cup + “dome” augment configuration: cup, typically placed too vertical and rela-
mean follow-up of 7.6 years. These results in elliptical, contained cavitary defects, tively retroverted in order to accommodate
are probably due to the ability of these cups when the anteroposterior dimension of the the cage; particular attention is needed in
to restore the hip center and achieve acetabulum precluded simply reaming up to cementing the liner with the right antever-
osseointegration through sufficient bone a jumbo socket (Paprosky type IIIA). sion and inclination.74 In addition, “half
cage” technique (without the ischial flange) 11% (57 of 516 hips) at mean 4.8 years nent (4 out of 20) that stabilized with time
has been described with a “kick-stand” showing a considerable improvement in and did not present clinical relevance. Sheth
screw positioned in the ischium or in the multiple functional scores. The authors also et al,77 reported survivorship from re-revi-
superior pubic ramus in order to avoid reported that the relatively high complica- sion due to aseptic loosening of 97% (1 fail-
abduction failure of the cup.14 tion rate in the CTACs may reflect the com- ure out of 32 cases) and radiographic loos-
plexity of revisions and severity of acetabu- ening of 6% (2 out of 32) at 5 years.
Custom Triflange Acetabular lar bone defects. In fact, the surgical tech- Radiographically, 69% of the cases (22 out
Components nique involves extensive soft tissue dissec- of 32) showed good healing of the disconti-
Custom triflange acetabular compo- tion with possible neuro-muscular damage11 nuity. Advantages of the acetabular distrac-
nents (CTACs) are a valid option in massive (Figure 2). tion may result in more reproducible heal-
periacetabular bone defects (Paprosky ing of a chronic pelvic discontinuity with a
Types IIIA and IIIB). The main advantage, Acetabular Distraction
theoretically decreased risk of subsequent
despite their high costs compared to other Acetabular distraction has been
implant loosening. Disadvantages are its
reconstruction implants, is the possibility to described as an alternative treatment in case
technically complexity and the not well
completely customize the implant starting of pelvic discontinuity (PD).76 The tech-
defined magnitude of distraction required
from a thin-cut computed tomography nique is based upon the placement of and
for adequate fixation.14 Further long-term
scan.75 The surgeon can decide the charac- extra-acetabular distractor to allow periph-
high-quality studies are needed to confirm
teristics of the component by selecting the eral or lateral distraction and central or
the survivorship of the implants and the
position of flanges, location and direction of medial compression at the discontinuity.
The technique provides initial mechanical clinical results.
screws, and number of holes. In addition,
the surgeon is able to plan the location, stability and, once bone healing occurs, bio-
inclination, and anteversion of the acetabu- logic fixation through a highly porous cup
lar cup. In order to facilitate osseointegra- placed into a distracted pelvic discontinuity.
tion, porous coatings and hydroxyapatite The presence of PD is usually confirmed Conclusions
are often applied to the flanges and back- intraoperatively. A stable fit of the cup with Acetabular bone defects are a major
side acetabular portion of the implant. A the anterosuperior and posteroinferior
concern in the setting of revision THA.
modular liner is placed into the central columns is mandatory in order to be a suc-
Paprosky classification system is the most
hemispherical cup and engaged with either cessful reconstruction option. Cement is
commonly used to describe the defects and
a modular locking mechanism or bone apposed in the interface between the aug-
guide treatment strategy. To date, as
cement.10,22 However, if osseointegration ment and the AC to reduce micromotions
assessed from this review, multiple recon-
is incomplete this implants are prone to and the cup is additionally stabilized with
struction options are available, and each
mechanical complications, especially in cancellous screws, two of which inferiorly
technique presents advantages and disad-
case of deficient superior support or in into the ischium or superior pubic ramus
vantages; however, the optimal method
pelvic discontinuity.10 In a recent systematic (“kickstand” screw) to avoid abduction fail-
should be selected according to the sur-
review, De Martino et al,22 reported that ure of the cup. Finally, the liner is then
geon’s experience, the appropriate preoper-
CTACs are a viable and effective way to cemented with the right version and inclina-
ative evaluation and classification of the
manage complex acetabular bone defects tion.74,76 Sporer et al,76 reported survivor-
bone defect associated with a correct plan-
with an overall complication rate of 29% ship from aseptic loosening of 95% (1 out
ning. Hemispherical uncemented cups sup-
(168 of 579 hips), reoperation rate of 17.3% of 20, at minimum 2 years) and 20% of
ported by screw fixation are recommended
(100 of 579 hips) and dislocation rates of early migration of the acetabular compo-
to address mild and moderate defects.
Highly porous metal cups and augments
showed satisfactory results in enhancing
bone ingrowth and fixation when used to
address severe bone defects. In case of
pelvic discontinuity good mid-term results
have been reported with the use of cup-
cage, custom triflange acetabular compo-
nents and acetabular distraction technique.
However, despite the overall good mid-term
outcomes, there is no consensus regarding
which reconstruction technique guarantees
better long-term survivorship due to the
lack of high-quality long-term studies on
the modern reconstructive options.
Finally, the outcome of revision THAs
depends on multiple factors including
patient selection, appropriate preoperative
evaluation of the bone defects, correct plan-
ning and templating, consideration of alter-
native strategies, proper reconstruction
options, and good postoperative care and
rehabilitation.
Figure 2. Example of highly porous cup with caudal hook and fins to ensure additional
stability. (Curtesy of LimaCorporate)
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