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Final Grand Case-Generalao
Final Grand Case-Generalao
Authors:
June 2023
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A Case Study on Choledochal Cyst Type I
Lovely Hope J. Lugatiman; Riz Strawberry G. Ilajas; Monica Marie T. Jubane; Joanna Paola S. Juntilla; Aprille
Dawn N. Lacbain; Clara Julia S. Loking; Francine Kaye Angela D. Maaño; Cyrill John B. Manliguez; Tazha
Camille D. Mondoñedo
Abstract:
This is a case of Patient X, a 15-year-old boy who was diagnosed with Choledochal
Cyst Type I and was admitted at Northern Mindanao Medical Center. Type I cysts are
fusiform dilatation of hepatic and common bile ducts. This is a rare medical condition
with an incidence of 1 in 100,000 to 150,000 live births in the western populations and 1
in 1,000 in Asian populations. This study aims to establish appropriate nursing
interventions and management in patient care and add to the limited existing studies
that are currently accessible regarding this disease. Patient X was noted to have a
palpable mass at the right upper quadrant, abdominal pain, jaundice, nausea, vomiting,
and generalized weakness. He had a Magnetic resonance cholangiopancreatography
(MRCP) with contrast Magnetic Resonance IMaging (MRI) and was found to have a
cystic lesion involving the hepatic and common bile ducts measuring approximately 11.6
x 13.1 x 17.3 centimeters. He then underwent a surgery for the excision of his
choledochal cyst and hepaticojejunostomy. His condition after the surgery improved, his
jaundice gradually subsided and there were no reports of abdominal pain, nausea, and
vomiting anymore. He was then discharged after the seventh postoperative day. Caring
for this patient enabled the researchers to institute Lydia Halls’ 3Cs; with the core or
center of care being the patient, the cure involves the medical and nursing interventions
instituted to the patient, and the care is the nurturing provided by nurses.
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ACKNOWLEDGEMENT
The researchers would like to express their deepest appreciation for the
generous support given to the participants of this study, our patient and his parents, who
were very forthcoming and gracious in accepting to participate in this case. If it were not
for their support and contributions, the following case would not have come to fruition.
To Ms. Lovely Terry Z. Caballes, LPT, RN, MN, the researchers would like to
extend their gratitude for the guidance and support during the times in which the
researchers conducted this study.
To Mr. Rey D. Pinalba, RN, MAN, the researchers would like to express their
thanks for the teachings, tough love, and patience. The growth and experience will be
put to good use in the future as nurses and supervisors.
To Ms. Daryl Mae A. Casirayan, RN, MN, the researchers would like to extend
our deepest thanks for guiding us throughout our consultations with you about this case
study. The work of creating this case study was rigorous and demanding, but without
your assistance, this research would not have been accomplished.
To Dr. Fidela B. Ansale, RN, MN, the researcher would like to express our
deepest gratitude for encouraging us to become a safe and better nurse when handling
our patients, for imparting to us the type of nurse that we should become in our future
endeavors.
The researchers would also like to extend their warmest thanks to each other
and their efforts put forth. It was worth it in the end.
To our beloved families, friends and classmates for the love, moral support and
guidance.
Above all, to the Heavenly Father, for the blessings, guidance, enlightenment and
protection, which made the researchers’ stronger amidst all the problems they
encountered along the way.
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INTRODUCTION
Choledochal cysts (CC) are congenital anomalies of the bile ducts and are
defined as abnormal, disproportionate, cystic dilatation of the biliary duct that involves
either extrahepatic duct, intrahepatic duct, or both (Khandelwal et al., 2013).
Substances normally excreted into the bile will accumulate in the vascular system owing
to obstruction of the biliary tree and the inability to excrete bile into the intestine (Wang
& Yu, 2014). Böyük et al. (2015) explained that CCs are classified into five types: Type I
cysts are fusiform dilatation of hepatic and common bile ducts; Type II involves
diverticular dilation anywhere along the extrahepatic duct; Type III cysts, involves
Intraduodenal cystic dilation of the distal common bile duct; Type IV cysts involves
multiple dilations affecting both the intrahepatic and extrahepatic biliary or may also
involve multiple dilations confined to the extrahepatic biliary tree; and Type V cysts
involves multiple dilations confined to the intrahepatic biliary tree. Choledochal cysts are
a rare anomaly and may sometimes be considered a premalignant condition, posing a
diagnostic dilemma (Khandelwal et al., 2013).
The typical clinical presentation of CCs include abdominal pain, jaundice, nausea
and vomiting, and a palpable mass in the right upper quadrant (Albuquerque et al.,
2020). Jaundice continues to serve as a warning indication for biliary tract abnormalities
in CC (Hadikusumah & Diposarosa, 2020). If left untreated, they can cause morbidity
and mortality from recurrent cholangitis, pancreatitis, sepsis, liver abscesses and
cholangiocarcinoma (Singham et al., 2019). Currently, worldwide, increasing access to
more accurate medical imaging enables early diagnosis, contributing to the use of
therapeutic methods in appropriate time, avoiding development of complications
(Albuquerque et al., 2020). However, the management of choledochal cyst and the
operative conduct will depend upon the patient comorbidities and choledochal cyst
subtype (Kelly et al., 2016).
Numerous explanations have been proposed as a result of the fact that the
precise etiology of CC is still unknown. The most widely accepted theory holds that the
cyst arises from an abnormal pancreaticobiliary junction (APBJ). APBJ occurs when the
pancreatic and biliary ducts converge 1 to 2 cm from the Oddi sphincter and as a result,
the long channel that is created is not blocked by the sphincter, allowing pancreatic and
biliary fluids to combine and flow backward, activating pancreatic enzymes. As a result,
the pressure increases, leading to the biliary tree's dilatation, inflammation, epithelial
damage, dysplasia, and cancer (Hoilat & Savio, 2022). However, some views contend
that this condition's genesis is solely congenital. According to Kusunoki et al. (2018),
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patients with CCs had fewer ganglionic cells than controls in the distal common bile duct
(CBD) which causes the proximal portion of the CBD to enlarge.
Sacher et al. (2013) reported that the preferred diagnostic test for a number of
biliary and pancreatic disorders during the past ten years has begun to shift from
Endoscopic retrograde cholangiopancreatography (ERCP) to Magnetic resonance
cholangiopancreatography (MRCP). MRCP is non-invasive, unlike ERCP procedure,
and involves a simple process of scanning the patient using magnetic and radio
frequencies from an MRI. The most effective methods of treatment for the typical kinds
of CC include precise imaging of the pancreatic and bile ducts, as well as any
accompanying pathology, radical excision of the extrahepatic bile ducts, and
reconstruction by wide hilar hepaticoenterostomy (Stringer, 2018).
The purpose of this case study is to explore and analyze the physiological
process of the disease, its medical-surgical management, and appropriate nursing care
for Obstructive Jaundice Secondary to Choledochal Cyst Type I.
At the end of this case study, the researchers will be able to outline the
physiological process of the disease, apply its medical management in the clinical
setting, and provide the optimum nursing management of patients with Choledochal
Cyst Type I to deliver the most efficient care for the patient.
This case study may have implications for nursing practice, more notably for
Nursing practice. The study’s prospective findings could assist nurses in managing
patient’s existing condition, providing appropriate medical management, educating
patients and their families about their condition and
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treatment. Collaborating with the health care team to ensure comprehensive patient
care can also assist them in ensuring holistic care and ensure positive patient
outcomes. Additionally, it can assist them in coordinating and managing the continuity of
care of the patient.
This case study may also potentially contribute to the field of Nursing research.
The study’s data and findings will provide additional data since only limited information
and studies are available regarding Choledochal Cyst Type I. Moreover, it will also
provide new data specifically for male pediatric population in the Philippines since
studies and this health condition is mostly focused on female pediatric populations in
Asia and in the U.S. More case studies similar to this case study can be conducted
which will cover the pediatric male population.
Nursing education can also benefit from this study. The result of this study
contributes to the understanding and knowledge of the nursing educators which allows
them to impart adequate information and equip students with the necessary theoretical
knowledge, practical skills, and clinical experiences needed to provide quality patient
care and make informed decisions in healthcare settings.
The scope of the study only covers for a week during the course of duty last May
22 - May 29, 2023 because the group was scheduled last for this rotation which enabled
us to assess the patient only for a short span of time.
Definition of Terms
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MRI machine uses a strong magnetic field and radio waves to create detailed images of
the bile ducts and pancreatic duct. MRCP can help diagnose bile duct abnormalities,
pancreatic disorders, gallbladder conditions, and biliary and pancreatic tumors. This
case study talks about Choledochal Cyst Type I where there is dilation or enlargement
of the common bile duct.
Excision of Choledochal cyst - Complete removal of a choledochal cyst from the bile
duct system. It is a surgical procedure performed to remove the abnormal cystic dilation
of the common bile duct (choledochal cyst). This procedure is considered the standard
treatment for choledochal cysts as it helps to alleviate symptoms, prevent
complications, and reduce the risk of long-term complications, including recurrent
infections, bile duct obstruction, and the development of cancer. In Obstructive Jaundice
Secondary to Choledochal Cyst Type I, there is presence of an abnormal sac or pouch
in the bile ducts.
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PATIENT’S PROFILE
Demographic Profile
In 2009, patient X was admitted for 5 days at Kalilangan Provincial Hospital due
to persistent vomiting for 2 days. He was only given intravenous fluids and was
observed and discharged after a day.
Three months prior to admission, patient X noticed a growing mass on his right
upper abdomen and experienced intense pain but tolerated it because he was worried
about his family’s finances.
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One month prior to admission, patient X was rushed to the Emergency Room of
Northern Mindanao Medical Center (NMMC) because of generalized weakness,
vomiting, fever and jaundice. Patient X was then admitted for one week for
management of present symptoms and relief of symptoms noted but his jaundice
persisted. He was then advised for re-admission on April 17, 2023 for scheduled
Magnetic Resonance Cholangiopancreatography (MRCP) with Contrast MRI and results
showed a well-defined cystic lesion involving the common hepatic and common bile
ducts measuring approximately 11.6 x 13.1 x 17.3 cm. Patient was then admitted for 5
days and was discharged thereafter because no surgeon was available to take on his
case.
Three days prior to admission, patient X’s family was called by NMMC for a
scheduled elective surgery on May 19, 2023. He was advised for admission two days
prior to the scheduled surgery.
On the day of admission, the institution informed patient X and his family that the
scheduled elective date of surgery was postponed and rescheduled to May 23,2023.
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Vital Signs
6 Day 1 (May 22, 2023); 6:00 PM 110/70 110 22 38.5 98 7/10 2400 900 1700 — 0
7 Day 2 (May 23, 2023); 7:30 PM 100/70 97 30 36.5 99 under anesthesia 2840 NPO 220 0 0
8 Day 3 (May 24, 2023); 5:00 PM 100/70 121 24 38.0 97 10/10 2400 NPO 400 NGT: 300cc, JP: 10cc 0
9 Day 4 (May 25, 2023); 5:00 PM 130/90 106 26 36.2 96 10/10 2400 NPO 800 JP: 150 cc 0
10 Day 5 (May 26, 2023); 5:00 PM 120/80 102 23 36.2 98 8/10 2240 NPO 1100 JP: 150cc 0
11 Day 6 (May 27, 2023); 5:00 PM 120/80 61 18 36.4 99 4/10 1920 500 1000 JP: 120 cc 0
12 Day 7(May 28, 2023); 5:00 PM 120/90 52 20 36.2 99 4/10 1920 480 1300 JP: 110 cc 0
13 Day 8 (May 29, 2023); 5:00 PM 110/80 63 20 36.5 99 4/10 1920 760 1200 JP- 100cc 0
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Day 1: May 22, 2023 Physical Assessment
First day of assessment, the patient appeared worried and nervous for the
upcoming surgery. When questioned, the patient looked away avoiding being asked.
Nutritional/Metabolic Pattern
Upon admission the patient was advised to be on a Low Fat Diet. Patient X has
poor appetite, weight loss noted from 41 kls to 38kls and is experiencing nausea and
vomiting. Furthermore, patients’ nutritional state is underweight. Assessment in the
mouth reveals yellowish oral mucosa, tongue is pinkish and the patient has missing
teeth. There are no wounds, drains, or dressings. Intravenous fluid-1L 0.9% Normal
Saline Solution regulated @30 gtts/min.
Elimination Pattern
Upon assessment, the patient can void independently and needs assistance with
a person in ambulating. The patient’s urine is orange-yellow in color and there were no
reports of defecation on the day of assessment. Last bowel movement was May 21,
2023 and it was a pale stool and soft in appearance.
Upon assessment, the patient can perform Range of Motion Movements but
limited with movement to the extremities. Patient can’t tolerate moving his truncal body
and needs assistance when transferring.
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Sleep and Rest Pattern
During assessment, Patient X is the eldest of the 4 siblings of his parents. Prior
to Admission, his parents are the one who helped him to be treated and admitted in the
hospital.
During assessment, The patient had no urinary problem but MRCP with Contrast
MRI shows bilateral renal cortical cysts with the largest one in the right likely containing
hemosiderin deposits and/or calcification. The patient does not have any prostate
problems and voids 3 to 4 times a day.
Patient X and his family are Roman Catholics. Their religious practices include
going to church and praying for good health and bounty.
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Day 2: May 23, 2023 Physical Assessment
Nutritional/Metabolic Pattern
Upon assessment, Patient X was advised for NPO until doctor’s order.
Elimination Pattern
Upon assessment, the patient had a Foley Bag Catheter attached with dark
orange-yellow output. There were no reports of defecation on the day of assessment.
Last bowel movement was May 21, 2023 and it was a pale stool and soft in
appearance.
Upon assessment, the patient can perform Range of Motion Movements but
limited with movement to the extremities. Patient can’t tolerate moving his truncal body
and needs assistance when transferring.
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During assessment, Patient X is oriented to time, person, and place. Patient X
does converse lightly but in a low voice, patient is weak and irritable. The patient's
primary language is Cebuano and has no speech deficit prior to admission.
During assessment, Patient X is assisted by his mother and father during hospital stay.
During assessment,The patient does not have any prostate problems and voids
through the catheter attached.
Patient X and his family are Roman Catholics. Their religious practices include
going to church and praying for good health and bounty.
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Day 3: May 24, 2023 Physical Assessment
On the third day of assessment, the patient appeared weak given that it is the
second postoperative day. When asked about his feelings, he would respond in a
single word and would nod his head in agreement with our statement. An NGT was still
present in the left nostril for gavage. Wound dressing was performed at the incision site.
Jackson Pratt drain was still attached at the RLQ with output of 600cc. A yellow sclera,
conjunctiva, and oral mucosa was noted and documented.
Nutritional/Metabolic Pattern
Upon assessment, Patient X was advised for NPO until doctor’s order.
Elimination Pattern
Upon assessment, the patient had a Foley Bag Catheter attached with dark
orange output. There were no reports of defecation on the day of assessment. Last
bowel movement was May 21, 2023 and it was a yellowish-colored stool and soft in
appearance.
Upon assessment, the patient can perform Range of Motion Movements but
limited with movement to the extremities. Patient can’t tolerate moving his truncal body
and needs assistance when transferring.
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an air conditioned endoscopy ward where there were only 2 patients inside including
him.
During assessment, Patient X is assisted by his mother and father during hospital
stay.
During assessment,The patient does not have any prostate problems and voids
through the foley bag catheter attached.
Patient X and his family are Roman Catholics. Their religious practices include
going to church and praying for good health and bounty.
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Day 4: May 25, 2023 Physical Assessment
Nutritional/Metabolic Pattern
Upon assessment, Patient X was advised for NPO until doctor’s order.
Elimination Pattern
Upon assessment, the patient had a Foley Bag Catheter attached with dark
orange-yellow output. There were no reports of defecation on the day of assessment.
No bowel movement postoperative day 3 but noted flatus 3x
Upon assessment, the patient can perform Range of Motion Movements but
limited with movement to the extremities. Patient can’t tolerate moving his truncal body
and needs assistance when transferring.
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Cognitive and Perceptual Pattern
During assessment, Patient X is assisted by his mother and father during hospital
stay.
During assessment,The patient does not have any prostate problems and voids
through the catheter attached.
Patient X and his family are Roman Catholics. Their religious practices include
going to church and praying for good health and bounty
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Day 5: May 26, 2023 Physical Assessment
Nutritional/Metabolic Pattern
Elimination Pattern
Upon assessment, the patient still had Foley Bag Catheter attached with dark
orange output. There were still no reports of defecation but had flatus 4 times already.
Last bowel movement was May 21, 2023 and it was a pale-colored stool and soft
appearance.
Upon assessment, the patient can perform Range of Motion Movements but with
limited movement to the extremities. Patient still cannot tolerate moving his truncal body
and needs assistance when transferring.
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Cognitive and Perceptual Pattern
During assessment, Patient X is the eldest of the 4 siblings of his parents. Prior
to Admission, his parents are the one who helped him to be treated and admitted in the
hospital.
The patient does not have any prostate problems and voids 3 to 4 times a day.
Patient X and his family are Roman Catholics. Their religious practices include
going to church and praying for good health and bounty.
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Day 6: May 27, 2023 Physical Assessment
Nutritional/Metabolic Pattern
Elimination Pattern
Upon assessment, the patient’s Foley Bag Catheter was removed. Patient
urinated 4x with amber in color. There were still no reports of defecation but had flatus 5
times already. Last bowel movement was May 21, 2023 and it was a yellowish-colored
stool and soft appearance.
Upon assessment, the patient can perform Range of Motion Movements but with
limited movement to the extremities. Patient still cannot tolerate moving his truncal body
and needs assistance when transferring
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During assessment, Patient X is oriented to time, person, and place. Patient X
does converse lightly but in a low voice, patient is weak and irritable. The patient's
primary language is Cebuano and has no speech deficit prior to admission.
During assessment, Patient X is the eldest of the 4 siblings of his parents. Prior
to Admission, his parents are the one who helped him to be treated and admitted in the
hospital.
The patient does not have any prostate problems and voids 3 to 4 times a day.
Patient X and his family are Roman Catholics. Their religious practices include
going to church and praying for good health and bounty.
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Day 7: May 28, 2023 Physical Assessment
On the 7th day of assessment, the patient was received lying in bed supine.
Patient was conscious and awake with yellowish sclera, conjunctiva, oral mucosa, and
light-yellow skin. Was able to eliminate gas from the stomach 5x. Edema was noted
bilaterally (R2+, L1+). NGT and FBC were removed, and were able to void 5x.
Nutritional/Metabolic Pattern:
Upon assessment, the patient was still on a liquid diet as per doctor’s order.
Elimination Pattern:
Upon assessment, the patient was able to void 4x and is amber in color. Patient
X was able to flatus 5x but still there were no reports of defecation.
Upon assessment, the patient can perform Range of Motion Movements but with
limited movement to the extremities. Patient still cannot tolerate moving his truncal body
and needs assistance when transferring.
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Cognitive and Perceptual Pattern
During assessment, Patient X is the eldest of the 4 siblings of his parents. Prior
to Admission, his parents are the one who helped him to be treated and admitted in the
hospital.
The patient does not have any prostate problems and voids 3 to 4 times a day.
Patient X and his family are Roman Catholics. Their religious practices include
going to church and praying for good health and bounty.
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Day 8: May 29, 2023 Physical Assessment
On the 8th day of assessment, the patient was received lying in bed supine
awake. Patient was conscious with yellowish sclera, conjunctiva, oral mucosa, and light
yellow skin. The patient is in pain and Was able to eliminate gas from the stomach 5x.
Edema was noted (R2+). NGT was removed, was able to void 3x. And patient X was
able to eliminate gas from the stomach 5x.
Nutritional/Metabolic Pattern:
Upon the assessment patient X is on a soft diet then diet as tolerated as per
doctor’s order.
Elimination Pattern:
Upon the assessment patient X was able to void 3x with yellowish colored urine.
The patient was able to pass flatus 5 times. And there were still no reports of
defecation.
Upon assessment, the patient can perform Range of Motion Movements but with
limited movement to the extremities. Patient still cannot tolerate moving his truncal body
and needs assistance when transferring.
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During assessment, Patient X is oriented to time, person, and place. Patient X
does converse lightly but in a low voice, the patient is weak. Patient X is cooperative
and responsive to questions and instructions. The patient's primary language is
Cebuano and has no speech deficit prior to admission.
During assessment, Patient X is the eldest of the 4 siblings of his parents. Prior
to Admission, his parents are the one who helped him to be treated and admitted in the
hospital.
The patient does not have any prostate problems and voids 3 to 4 times a day.
Patient X avoids questions about his ailment during the evaluation. He is still
adjusting to the illness he experienced. On the eighth day of the examination, he
showed signs of weakness.
Patient X and his family are Roman Catholics. Their religious practices include
going to church and praying for good health and bounty.
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Anatomical Model
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Day 2 of Assessment: May 23 , 2023
Hospital Day: 7
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Day 3 of Assessment: May 24, 2023
Hospital Day: 8
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Day 4 of Assessment: May 25, 2023
Hospital Day: 9
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Day 5 of Assessment: May 26, 2023
Hospital Day: 10
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Day 6 of Assessment: May 27, 2023
Hospital Day: 11
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Day 7 of Assessment: May 28, 2023
Hospital Day: 12
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Day 8 of Assessment: May 29, 2023
Hospital Day: 13
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Patient’s Developmental Stage
A. Psychosexual Development
Sigmund Freud
This stage occurs during puberty and extending into adulthood, plays a pivotal
role in shaping individuals’ sexual desires, relationships and overall psychological
well-being and it marks a significant milestone in human development (Mcleod, 2023).
Understanding the complexities and significance of the genital stage empowers
individuals to embrace their sexual desires and fulfill personal growth (Mcleod, 2023).
Patient X is in the stage of becoming more aware of his body and attractions
towards other gender. The mother stated that his son has a lot of friends, also he has a
crush at his school but he gives more importance to his education and to help his
parents than entering a relationship at an early age. Patient X does not disclose any
relationship because he felt embarrassed and shy.
B. Psychosocial Theory
Erik Erikson
Patient X is in the stage of developing a sense of identity and figuring out what
he wants to become in life. Patient X mentioned that he wants to finish college and
become a police officer. He wants to help his parents and other people who need help.
Patient X shows a sense of identity and has a clear view about the future, interest and
self-confidence. His mother said that he is an independent person and a good role
model to his siblings, as a typical kid he loves teasing and goofing around above all of
that he takes good care of his younger siblings.
Jean Piaget
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This stage opens up new avenues for intellectual growth, creativity, and the
exploration of diverse possibilities represents a significant leap in cognitive
development, enabling individuals to transcend concrete thinking and embrace abstract
reasoning, hypothetical thinking, logical deduction, metacognition, and complex
problem-solving (Lynch, 2021).
The mother said that patient X is smart and hard working. He aced in his class
and always got a good grade. Even though their financial situation is uneasy it’s not a
burden to him and he still wants to go to school, he also helps his siblings doing their
homework and helps them in terms of numbers. The mother stated his son is a logical
thinker and able to solve a problem without help from them.
D. Moral Development
Lawrence Kohlberg
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THEORETICAL AND CONCEPTUAL FRAMEWORK
Orem's theory of self-care states that everyone has the capacity and
responsibility to engage in self-care activities in order to preserve their health and
well-being (Hartweg, 2015). Self-care deficiencies happen when people struggle with or
are unable to accomplish certain self-care tasks. Deficits in self-care can occur for a
number of reasons, including disease, injury, disability, ignorance of available services,
and lack of knowledge (Hartweg, 2015). Nursing interventions are put in place when a
self-care gap is found to assist people in meeting their requirements (Hartweg, 2015).
The ability of the patient to complete self-care tasks is evaluated by nurses, which
additionally provide information, support, and assistance as needed (Hartweg, 2015).
We choose Dorothea Orem because of our patient's condition, which makes him
unable to care for himself or perform basic personal hygiene tasks. The responsibility of
self-care cannot be reached due to inability to perform the normal hygienic tasks.
Nurses' responsibilities include supporting the patient, imparting knowledge, and
assisting in goal-setting. Addressing self-care deficits is crucial for promoting overall
health and preventing complications. By assisting individuals in meeting their self-care
needs, healthcare professionals aim to enhance their independence, improve their
quality of life, and facilitate their recovery and well-being.
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Jacobson, 2020). This approach fosters trust, improves communication, and
strengthens the therapeutic relationship (Vaughan & Jacobson, 2020).
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ANATOMY AND PHYSIOLOGY
ABDOMEN
The abdomen (commonly called the belly) is the body space between the thorax
(chest) and pelvis (Park & Singh, 2017). The diaphragm forms the upper surface of the
abdomen. At the level of the pelvic bones, the abdomen ends and the pelvis begins
(Park & Singh, 2017).The abdomen contains all the digestive organs, including the
stomach, small and large intestines, pancreas, liver, and gallbladder (Park & Singh,
2017). These organs are held together loosely by connecting tissues (mesentery) that
allow them to expand and to slide against each other. The abdomen also contains the
kidneys and spleen (Park & Singh, 2017).
Many important blood vessels travel through the abdomen, including the aorta,
inferior vena cava, and dozens of their smaller branches (Hoffman, 2020). In the front,
the abdomen is protected by a thin, tough layer of tissue called fascia (Hoffman, 2020).
In front of the fascia are the abdominal muscles and skin and in the rear of the
abdomen are the back muscles and spine (Hoffman, 2020).
STOMACH
The stomach is a sac-like organ that's an important part of the digestive system
(Rad, 2022). After food is chewed and swallowed, it enters the esophagus, a tube that
carries food through the throat and chest to the stomach (Rad, 2022).
SPLEEN
The spleen is an organ in the upper far left part of the abdomen, to the left of the
stomach (Kapila et al., 2022). The spleen varies in size and shape between people,
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but it’s commonly fist- shaped, purple, and about 4 inches long (Kapila et al., 2022).
Because the spleen is protected by the rib cage, you can’t easily feel it unless it’s
abnormally enlarged (Kapila et al., 2022).
LIVER
The liver is the largest solid organ in the body (Kalra et al., 2021). It removes
toxins from the body's blood supply, maintains healthy blood sugar levels, regulates
blood clotting, and performs hundreds of other vital functions (Kalra et al., 2021). It is
located beneath the rib cage in the right upper abdomen (Kalra et al., 2021).
GALLBLADDER
Its main function is to store bile, which helps your digestive system break down
fats. Bile is a mixture of mainly cholesterol, bilirubin and bile salts Basit et al., 2022).
SMALL INTESTINE
The small intestine or small bowel is an organ in the gastrointestinal tract where
most of the absorption of nutrients from food takes place (Rad, 2022). It lies between
the stomach and large intestine, and receives bile and pancreatic juice through the
pancreatic duct to aid in digestion (Rad, 2022).
LARGE INTESTINE
The large intestine, also known as the large bowel, is the last part of the
gastrointestinal tract and of the digestive system in vertebrates (Hoffman, 2020).. Water
is absorbed here and the remaining waste material is stored in the rectum as feces
before being removed by defecation (Hoffman, 2020).
DIGESTIVE ENZYMES
Maltose
Exopeptidase
An enzyme that triggers the cleavage of the terminal (last) or next-to-last peptide
bond from a polypeptide or protein, releasing a single amino acid or dipeptide (Stöppler,
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2021). An endopeptidase, on the other hand, catalyzes the breakage of internal peptide
bonds inside a polypeptide or protein (Stöppler, 2021).
Nucleases
Enzymes called nucleases break down nucleic acids (Yang, 2016). These are
divided into deoxyribonucleases (DNases), which attack DNA, and ribonucleases
(RNases), which target RNA, although the level of specificity varies widely, the majority
of nucleases are specific (Yang, 2016).
Peptidase
Enzymes are able to cleave small peptides, frequently rendering them inactive in
the process (Hulsmann, & Velden, 2017). The catalytic site is only visible at the external
surface, and they are extensively dispersed on the surface of several distinct cell types
(Hulsmann, & Velden, 2017).
Lactase
Sucrase
Located on the outer surface of intestinal epithelial cells, which are the cells that
line the intestine's walls (Amiri et al, 2017). These cells feature fingerlike extensions
known as microvilli that absorb nutrients from food as it travels through the intestine
(Amiri et al, 2017).
Lipase
Amylase
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The enzyme or particular protein that aids in the breakdown of carbohydrates (Ali
& Nater, 2020). Pancreas and salivary glands produce the majority of the amylase that
is found in your body. It's normal to have a tiny quantity of amylase in your blood and
urine (Ali & Nater, 2020).
Phospholipase
Enzymes known as lipolytics that break down certain ester bonds in phospholipid
substrates (Pirahanchi, 2022). Phospholipases are widely distributed in nature and have
a wide range of functions, from producing lipid mediators, signal transmission, and the
digestion of metabolites in humans to causing aggressiveness in snake venom
(Pirahanchi, 2022). The structure, purpose, control, and mechanism of action of
phospholipases vary widely (Pirahanchi, 2022).
Endopeptidase
43
DIAGNOSTIC AND LABORATORY TESTS
An increase of white blood cell count (WBC) and neutrophil count are the first
signs of inflammation in acute appendicitis; however, the sensitivity and diagnostic value
vary widely, depending on the study population, the severity of symptoms, and
laboratory results. A complete blood count (CBC) is a very common blood test
performed in laboratories and is performed in emergency room surgeons as part of a
preoperative evaluation to determine inflammatory lesions. Other factors, such as the
neutrophils-to-lymphocytes ratio (NLR), platelet count (PLT), mean platelet volume
(MPV), platelet distribution width (PDW), and red cell distribution width (RDW), are
investigated to improve the accuracy of the preoperative diagnosis of appendicitis
(Maghsoudi et al, 2021).
44
Ascites inside the small bowel mesenteric leaves and gut wall thickening are signs of
colon ischemia alterations caused by blockage (Takahirto et al, 2021)
X-ray computed tomography (CT) may give unequaled information on the interior
structure of materials non-destructively from the meters down to the tens of nanometer
length scales. It makes use of the penetrating X-ray power to generate a succession of
two-dimensional images (2D) radiography of the item taken from various angles. This
procedure is also known as a CT scan.Then, a calculated reconstruction procedure is
applied to construct a stack of cross-sectional slices from these 2D sections. (Philip J et
al, 2021)
One of the primary benefits of X-ray CT imaging, its advantage over other procedures,
is that it is non-destructive. This is essential for analyzing sensitive materials that cannot
be handled when the structural integrity can be readily compromised before an
engineering component may be used (Philip J et al, 2021)
URINALYSIS
Urinalysis is a useful tool for clinicians. It is most likely widely used in the
evaluation of the genitourinary system; also, it can help in the identification of certain
diseases. Diabetes mellitus and pregnant hypertension are examples of systemic
illnesses. The physical, chemical, and microscopic examination of a urine specimen is
included in a complete urinalysis. The physical examination describes the visual
appearance and measured concentration of the urine. Chemical analysis, which is
mostly conducted via dipstick technology, is used to uncover and quantify important
urine components. The third main component of urinalysis is microscopic assessment; it
is the most time-consuming component, but it is essential. Urinary tract infections and
kidney damage continue to be important diagnosis (Shu Ling, 2020)
45
PROTHROMBIN TIME
The prothrombin time (PT) is the most often used co-agulation test, and it was
developed by Dr. Armand Quick and colleagues in 1935. The PT is a single-stage
screening test used to evaluate tissue factor (TF) and common coagulation pathways,
and is thus impacted by coagulation factor and fibrinogen activity.
In clinical laboratories, the prothrombin time (PT) is the most often used
coagulation test. To offer test findings that are adjusted for thromboplastin and
instrument used, the PT is mathematically transformed to the international normalized
ratio (INR) for use in monitoring anticoagulant treatment with vitamin K antagonists such
as warfarin (Dorgalaleh et al, 2020).
C-REACTIVE PROTEIN
Inflammation is your body's way of protecting your tissues and helping them heal
from an injury, infection, or other disease. Inflammation can be acute (sudden) and
temporary. This type of inflammation is usually helpful. For example, if you cut your skin,
it may turn red, swell, and hurt for a few days. Those are signs of inflammation.
Inflammation can also happen inside your body.
The term "liver function tests" pinpoint the source of the damage. Elevated ALT
and AST levels that are out of proportion to ALP and bilirubin indicate hepatic illness.
Most liver diseases generate very minor symptoms at first, but they must be diagnosed
as soon as possible. Hepatic involvement in various disorders can be critical. This
testing is done on a blood sample from a patient. Some tests are connected with
46
functioning, some with cellular integrity, and yet others with bile tract problems
(Iluz-Freundlich D et al. 2020).
There is a huge, well-defined cystic mass in the right to mid upper abdomen measuring
14.4 x 11.5 x 9.78 cms (850 mL). The cyst is contiguous to the pancreatic head and
displaces the common bile duct superiorly.
47
The intrahepatic ducts are dilated and also the common bile duct with the widest
diameter measuring 1.49 cm. There is dilation of the pancreatic duct as well.
There are cortical cysts in both kidneys; in the right measures 1.67 cms located in the
superior pole and 1.88 cms in the left mid cortex.
IMPRESSION:
● Huge, well-defined cystic mass in the right to mid upper abdomen - large
choledochal cyst versus a pancreatic head cyst, for clinical correlation.
● Intra and extrahepatic biliary ectasia and pancreatic duct ectasia - secondary
● Renal cortical cysts, bilateral
Interpretation
Since the patient is diagnosed with Choledochal cyst type I, the presence of
intrahepatic and extrahepatic biliary ectasia suggests the involvement of both the bile
ducts within and outside the liver. Additionally, the pancreatic duct ectasia indicates the
dilation of the pancreatic duct, which can occur as a secondary effect, probably a mass
effect of the choledochal cyst.
Bilateral renal cortical cysts refer to the presence of cysts in both kidneys within
the renal cortex, these cysts are common and often benign. The cyst typically develops
as a result of fluid accumulation in the kidney tissue, leading to the formation of a
sac-like structure. Most renal cortical cysts are considered simple cysts, which means
they have a thin wall and contain clear fluid. Simple cysts do not typically require
treatment unless they cause symptoms or complications, such as pain, infection, or
obstruction of the urinary tract.
MRCP shows a well-defined T1 cystic lesion involving the common hepatic and
common bile ducts measuring approximately 11.6 x 13.1 x 17.3 cm. Minimal layering T1
48
hyperintense- T2 isointense foci are noted within the dependent portion relating to bile
sludge. There is a mass effect onto the adjacent pancreatic head, duodenum and
kidney. There is evidence of dilatation involving the central intrahepatic duct-biliary
radicals.
The gallbladder is normal in size without intraluminal calculus. The wall is not thickened.
IMPRESSION:
● Large cystic lesion involving the common hepatic and common bile ducts with
associated central intrahepatic duct-biliary radical dilatation likely from mass
effect. Consider a large choledochal cyst (Type 1) with minimal layering
intraluminal bile sludge exerting mass effect onto the adjacent structures.
● Bilateral renal cortical cysts, with the largest one in the right likely containing
hemosiderin deposits and/or calcification.
● Minimal perihepatic and perisplenic ascites.
●
Interpretation
The first clinical impression suggests that the large cystic lesion is likely a
choledochal cyst, specifically a Type 1 choledochal cyst. There is a suspicion of a large
choledochal cyst (Type 1) that is causing dilation of the central intrahepatic bile ducts
and exerting a mass effect on adjacent structures. The presence of intraluminal bile
sludge within the cyst is further contributing to the mass effect. The second impression
suggests the presence of multiple renal cortical cysts in both kidneys, with the largest
cyst located in the right kidney. The presence of hemosiderin deposits and/or
calcification within the largest cyst indicates past bleeding within or around the cortical
cyst and potential mineral deposition. The presence of minimal perihepatic and
49
perisplenic ascites suggests that there is a small amount of fluid accumulation around
the liver and spleen.
URINALYSIS
50
Color Amber Amber Dark The urine color is
Yellow normal
Interpretation
There is a presence of RBC in the urine of our patient, which is caused by the
presence of bleeding within or around the cortical cyst. RBCs may be released into the
urine, resulting in hematuria. Over time, the breakdown of RBCs can lead to the
accumulation of hemosiderin deposits. Hemosiderin deposits in the kidneys, along with
hematuria, may indicate chronic or recurrent bleeding associated with the renal cortical
cysts. The presence of hemosiderin deposits does not directly cause hematuria but
rather indicates previous episodes of bleeding. Based on the urinalysis, there is a
presence of WBC and coccus in the urine, which indicates an inflammation or infection.
51
Based on the MRI and CT scans of the patient, there is the presence of bilateral
renal cortical cysts, with the largest one on the right likely containing hemosiderin
deposits and/or calcification. In the case of a cyst with calcification, there may be
leakage or rupture of the cyst, leading to the release of calcified material into the urinary
system. This can result in the presence of calcium crystals in the urine. The presence of
mucus strands in the urine is caused by renal cortical cysts, causing obstruction in the
urinary tract. This obstruction may trigger the production of mucus strands in response
to irritation or injury. In the month of March, the patient experienced dehydration, which
caused him to have an increased urine specific gravity.
Measuring bilirubin in the urine is a valuable diagnostic tool that helps assess the
function of the liver and the biliary system. In the case of patient X, he had a biliary
obstruction that resulted in the accumulation of bilirubin in the bloodstream and its
subsequent excretion in the urine.
There is an increase in microalbumin in the urine since the patient has bilateral
renal cortical cysts, which can interfere with the normal function of the kidneys. This can
lead to leakage of the blood and albumin into the urine.
Nitrate is a chemical compound that is normally not present in the urine. The
presence of nitrite in the urine is a result of bacterial activity, specifically the conversion
of nitrates by bacteria, and since there is an elevated level of nitrate in the urine of the
patient, this indicates an inflammation or infection.
Leukocytes play a crucial role in the body's immune response to infection and
inflammation. An increased amount of leukocytes in the urine suggests that there is
inflammation or infection in the urinary tract.
52
COMPLETE BLOOD COUNT (CBC)
Results
Test Unit of Reference Implications
March 18, March 22, March 25, March 28, April 4, April 15, April 23, April 28, Measurement Values
2023 2023 2023 2023 2023 2023 2023 2023
WBC 11.90 (H) 10.23 (H) 11.98 (H) 10.74 (H) 9.91 9.55 9.77 11.09 (H) x103 uL 5.0 - 10.0 Presence of inflammation.
RBC 4.78 4.18 (L) 4.35 3.98 (L) 3.62 (L) 3.87 (L) 4.57 4.27 x106 uL 4.2 - 5.4 Decreased amount of RBC circulating in
blood. Caused by impaired liver function.
Hgb 13.30 11.70 (L) 12.00 10.80 (L) 9.80 (L) 10.50 (L) 12.20 11.90 (L) g/dL 12.0 - 16.0 Less concentration of oxygen carrying
proteins in blood. Caused by impaired
liver function.
Hct 40.50 35.40 (L) 35.70 33.30 (L) 29.90 32.10 (L) 38.40 35.20 (L) % 37.0 - 47.0 Decreased percentage of RBC per
(L) volume.Caused by impaired liver function.
MCV 84.70 84.70 82.10 83.70 82.60 82.90 84.00 82.40 fL 82.0 - 98.0 Normal red blood cell size.
MCH 27.80 28.00 27.60 27.10 27.10 27.10 26.70 (L) 27.90 pg 27.0 - 31.0 Decrease the amount of oxygen carrying
protein per cell of RBC. Caused by
impaired liver function.
MCHC 32.80 33.10 33.60 32.40 32.80 32.70 31.80 33.80 g/dL 31.5 - 35.0 Normal amount of oxygen carrying protein
per cell of RBC.
RDW 17.10 (H) 16.50 16.50 16.90 16.60 17.70 (H) 17.00 16.30 % 12.0 - 17.0 Increased values of variability shaped and
sized red blood cells.Caused by
inflammation in the bile duct secondary to
biliary obstruction.
PDW 9.90 11.00 9.70 10.20 10.40 10.70 12.90 10.50 fL 9.0 - 16.0 Normal platelet size
MPV 9.60 10.00 9.30 9.80 10.40 10.20 10.60 10.00 fL 8.0 - 12.0 Average size of platelets found in blood.
53
DIFFERENTIAL COUNT
Neutrophil 75.70 62.70 61.50 61.20 64.90 77.40 (H) 64.80 67.10 % 43.4 - 76.2 Presence of Inflammation
Lymphocyte 13.70 (L) 20.90 24.40 21.50 20.10 8.40 (L) 22.80 17.20 (L) % 17.4 - 48.2 Presence of Inflammation
Monocyte 7.50 10.10 8.70 10.10 8.60 10.60 (H) 6.40 10.10 % 4.5 - 10.5 Presence of Inflammation .
Eosinophil 2.00 4.70 (H) 4.20 (H) 5.70 (H) 5.00 (H) 2.30 5.00 (H) 4.60 (H) % 1.0 - 3.0 Increased number of eosinophils
circulating in peripheral blood
due to Presence of iInflammation
Basophil 1.10 1.60 1.20 1.50 1.40 1.30 1.00 1.00 % 0.0 - 2.0 Normal Range
Platelet 588 (H) 388 440 (H) 435 (H) 409 (H) 442 (H) 181 346 x103 uL 150 - 400 Increased clotting
Count factors/Coagulators. Caused by
possible inflammation on the bile
duct secondary to biliary
obstruction.
54
Interpretation:
During the course of our assessment from March 18 to 28 and April 28 the
patient had an increase in white blood cells which showed that there was an
inflammation. One way to determine if there is an infection in the WBC count of the
patient. This supports the diagnosis of the patient with Choledochal cyst which is a
biliary obstruction that can cause the liver to have accumulation of bile and subsequent
hepatocellular injury which triggers an immune response, leading to the release of
inflammatory mediators and the recruitment of white blood cells to the liver. This
immune response can cause an increase in WBC count.
RBC, Hemoglobin count as well as the hematocrit was low. Since hemoglobin is
a protein in red blood cells that carries oxygen throughout the body and the hematocrit
blood test determines the percentage of red blood cells (RBC’s) in the blood, a low
RBC, hemoglobin and hematocrit indicate that the patient had a choledochal cyst which
results to Obstructive jaundice, caused by the obstruction of the bile ducts, leads to the
accumulation of bilirubin in the bloodstream. If there is prolonged obstruction and the
bilirubin levels become high, it can lead to an indirect effect on red blood cells. The
excess bilirubin can be deposited in the bone marrow, where red blood cells are
produced, potentially affecting their production. This disruption in red blood cell
production may contribute to anemia.
The platelet count is high since the choledochal cysts can lead to inflammation
and damage to the bile ducts and surrounding tissues. This inflammatory response can
55
stimulate the production of platelets in the bone marrow, leading to an increase in
platelet count. While the basophil is normal during the course of assessment.
56
BLOOD CHEMISTRY
Creatinine/BUN
Results
Test Unit of Reference Value Implications
March 18, March 22, March 28, April 4, April 15, April 24, April 28, Measurement
2023 2023 2023 2023 2023 2023 2023
Creatinine 0.63 0.80 0.84 0.58 (L) 0.72 0.52 (L) 0.70 mg/dL 0.6 - 1.8 mg/dL Impaired kidney function
Albumin
Results
Test Unit of Measurement Reference Value Implications
March 18, March 25, April 4,
2023 2023 2023
Albumin 3.64 (L) 3.04 (L) 3.4 (L) g/dL 3.8 - 5.1 g/dL Impaired liver function. Losses from Albuminuria.
Bilirubin
Results
Test Unit of Reference Value Implications
March 18, March 30, April 4, April 15, April 28, Measurement
2023 2023 2023 2023 2023
Direct Bilirubin 7.41 (H) 2.75 (H) 5.87 (H) mg/dL 0.00 - 0.25 mg/dL Presence of choledochal cyst
Indirect Bilirubin 1.5 (H) 1.16 (H) 1.2 (H) mg/dL 0 - 1.0 mg/dL Presence of impaired liver function
Total Bilirubin 8.40 (H) 8.86 (H) 8.70 (H) 3.91 (H) 7.04 (H) mg/dL 0.2 - 1.3 mg/dL Presence of impaired liver function
57
Amylase
Results
Test Unit of Measurement Reference Value Implications
March 18, March 26,
2023 2023
Amylase 166 (H) 134 (H) U/L 30 -110 U/L Presence of pancreatic duct ectasia
Electrolytes
Results
Test Unit of Reference Implications
March 18, March 22, March 25, March 28, April 4, April 24, April 28, Measurement Value
2023 2023 2023 2023 2023 2023 2023
Potassium 4.10 3.57 3.80 3.60 3.19 (L) 4.97 3.94 mmol/L 3.5 - 5.3 Presence of impaired liver function.
mmol/L
Sodium 144.03 144.2 143.04 141.09 139.3 143.9 141.61 mmol/L 135 - 148 Normal Range
mmol/L
Phosphorus 4.63 (H) mg/dL 2.5 - 4.5 Presence of Bilateral Renal Cortical
mg/dL cyst.
Liver Profile
Results
Test Unit of Reference Implications
March 18, March 22, March 25, April 4, April 15, Measurement Value
2023 2023 2023 2023 2023
S.G.O.T/AST 135.4 (H) 89.0 (H) 96.8 (H) 77 (H) 114 (H) U/L 17 - 59 U/L Liver injury secondary Bile duct obstruction.
S.G.P.T/ALT 60.20 (H) 45.4 (H) 44 (H) 46 (H) 42 U/L 0 - 42 U/L Presence of Biliary obstruction
Alk. Phosphate 1143.0 (H) 1027 (H) 646 (H) U/L 80 - 306 U/L Presence of Billiary obstruction
58
59
Interpretation:
One way to determine the renal function of the patient is to determine its BUN
and creatinine levels in the blood. Since the patient was diagnosed with a choledochal
cyst that can lead to complications caused by the biliary obstruction which can directly
affect the kidney function (Arihan et al., 2018).
Upon our assessment There was a decreased level of creatinine in the blood
which signifies that the patient has an impaired kidney function related to his Bilateral
Renal Cortical cyst. While the Blood Urea Nitrogen (BUN) is within normal range during
our assessment on April 14th.
Albumin is a protein made by the liver. Albumin keeps the fluid from leaking out
of blood vessels; nourishes tissues and transports hormones, vitamins, drugs, and
substances like calcium throughout the body. Low levels of albumin indicates that there
is Inflammation or infections taking place, and low levels may be due impaired function
of the liver to create albumin and due to renal losses.
Indirect bilirubin is the initial form produced by the breakdown of red blood cells,
while direct bilirubin is the water-soluble form that is conjugated in the liver and excreted
in bile. Total bilirubin represents the sum of both indirect and direct bilirubin and is used
as a measure of overall bilirubin levels in the body; it is measured as a diagnostic
marker to assess liver function. During our assessment patient X has an impaired liver
function caused by biliary obstruction which resulted in Hyperbilirubinemia. Normally,
the liver conjugates bilirubin, converting it from its unconjugated (indirect) form to its
conjugated (direct) form for excretion into the bile. In the case of biliary obstruction, the
liver's ability to process bilirubin is impaired, leading to elevated levels of unconjugated
bilirubin in the blood.
The liver plays a vital role in the regulation of potassium levels in the body. It
actively takes up potassium from the bloodstream and stores it within liver cells.The
patient had a normal potassium levels during the assessment days, but on the April 4th
60
of assessment, there was sudden decrease of potassium level which indicates that the
patient has a liver dysfunction, which is the liver's ability to uptake and store potassium
is impaired, leading to decreased potassium levels in the bloodstream. And the level of
sodium within the course of our assessment is within normal levels.
61
ACTIVATED PARTIAL THROMBOPLASTIN TIME
APTT April 23, 2023 51.8 (H) 34.1 seconds 23.4 - 38.5 seconds Increased duration APTT caused by liver dysfunction
PROTHROMBIN TIME
March 18, 2023 21.6 (H) 13.9 1.55 Increased duration of prothrombin
Prothrombin seconds 11.0 - 16.0 time caused by liver dysfunction.
Time seconds
March 22, 2023 30.1 (H) 13.3 2.26 Increased duration of prothrombin
time caused by liver dysfunction.
April 24, 2023 19.5 (H) 13.9 1.40 Increased duration of prothrombin
time caused by liver dysfunction.
April 26, 2023 19.0 (H) 14.1 1.34 Increased duration of prothrombin
time caused by liver dysfunction.
62
Interpretation
Activated partial thromboplastin time measures how long it takes your blood to
form a clot, and a prothrombin time test measures how quickly your blood clots, and this
uses a sample of your blood. Prothrombin is a protein produced by your liver. Normally,
when one of the blood vessels is damaged, proteins in your blood called clotting factors
come together in a certain order to form blood clots and quickly stop bleeding. During
the course of our assessment, there was a longer duration of activated partial
thromboplastin time, and the duration of prothrombin time was beyond normal.
Normally, the liver is responsible for synthesizing clotting factors. These factors are
essential for the normal clotting process. In the context of choledochal cysts, since the
patient has impaired liver functioning caused by the biliary obstruction, this affects the
synthesis of clotting factors, leading to abnormal aPTT and prothrombin time results.
The patient has to take vitamin K supplements because of the increased duration of
aPTT, and PTT also indicates a vitamin K deficiency. Vitamin K is essential for the
synthesis of several clotting factors, and its deficiency can result in abnormal
coagulation tests, including prolonged APTT and PTT.
63
COMPLETE BLOOD COUNT (CBC)
May 2023
Results
Test Unit of Reference Implications
May 17, May 22, May 23, May 24, May 25, May 28, May 29, Measurement Values
2023 2023 2023 2023 2023 2023 2023
WBC 12.44 (H) 9.43 12.18 (H) 9.41 8.81 6.84 8.17 x103 uL 5.0 - 10.0 Presence of inflammation.
RBC 4.30 3.65 (L) 3.88 (L) 3.45 (L) 3.94 (L) 4.27 4.13 (L) x106 uL 4.2 - 5.4 Decreased amount of RBC circulating in blood. Caused
by impaired Liver function.
Hgb 11.30 (L) 9.70 (L) 10.60 (L) 9.40 (L) 10.80 (L) 12.20 11.70 (L) g/dL 12.0 - 16.0 Less concentration of oxygen carrying proteins in
blood. Caused by impaired Liver function.
Hct 34.60 (L) 29.60 (L) 32.70 (L) 28.30 (L) 33.30 (L) 36.40 (L) 35.50 (L) % 37.0 - 47.0 Decreased percentage of RBC per volume. Caused by
impaired Liver function.
MCV 80.50 (L) 81.10 (L) 84.30 82.00 84.50 85.20 86.00 fL 82.0 - 98.0 Decreased red blood cell size. Caused by impaired
Liver function.
MCH 26.30 (L) 26.60 (L) 27.30 27.20 27.40 28.60 28.30 pg 27.0 - 31.0 Decreased amount of oxygen. Caused by impaired
Liver function.
MCHC 32.70 32.80 32.40 33.20 32.40 33.50 33.00 g/dL 31.5 - 35.0 Normal amount of oxygen carrying protein per cell of
RBC
RDW 16.60 16.60 16.60 16.20 16.10 15.70 16.10 % 12.0 - 17.0 Normal values of variability shaped and sized red blood
cells
PDW 11.40 9.50 9.30 9.20 10.20 10.20 11.10 fL 9.0 - 16.0 Normal platelet size
MPV 10.10 9.20 9.60 9.70 10.20 10.00 10.30 fL 8.0 - 12.0 Average size of platelets found in blood
64
DIFFERENTIAL COUNT
Neutrophil 66.20 61.50 81.20 (H) 71.30 69.60 60.70 % 43.4 - 76.2 Presence of inflammation.
Lymphocyte 20.30 23.50 10.30 (L) 16.50 (L) 15.80 (L) 23.20 % 17.4 - 48.2 Presence of inflammation.
Monocyte 7.80 8.80 7.30 9.60 9.00 7.90 % 4.5 - 10.5 Normal Range
Eosinophil 4.30 (H) 4.70 (H) 0.30 (L) 1.50 4.10 (H) 6.60 (H) % 1.0 - 3.0 May 17, 22, 25, 28, 2023 there is an
increased level of eosinophils circulating in
the peripheral blood. Due to the presence of
inflammation.
Basophil 1.40 1.50 0.90 1.10 1.50 1.60 % 0.0 - 2.0 Normal Range
Platelet Count 305 377 363 342 347 364 x103 uL 150 - 400 Normal Range
65
Interpretation:
During our assessment on May 17 to 29, the patient had a significant increase in
white blood cells on the 17th of May and the 23rd of May which showed that the body is
fighting off infection. There was a drop in RBC, which indicates that there was
inadequate oxygen circulating in the body. RBCs carry hemoglobin, which transports
oxygen to our tissues. The amount of oxygen delivered to your tissues can be affected
by the quantity of RBCs you have. This manifestation is the result of his condition's
pathophysiological repercussions on his body.
Hemoglobin and hematocrit count was low, given that hemoglobin is a protein
found within red blood cells that ships oxygen throughout the body, and the hematocrit
blood test determines the percentage of red blood cells (RBCs) in the blood, low levels
of both indicate that the patient had a choledochal cyst, which leads to liver dysfunction
or damage, impairing RBC and hemoglobin production.
66
BLOOD CHEMISTRY
May 2023
Creatinine
Results
Test Unit of Reference Value Implications
May 17, May 22, May 23, May 24, May 28, May 29, Measurement
2023 2023 2023 2023 2023 2023
Creatinine 0.70 0.50 (L) 0.47 (L) 0.64 0.60 0.70 mg/dL 0.6 - 1.8 mg/dL Impaired kidney function.
Albumin
Results
Test Unit of Measurement Reference Value Implications
May 17, May 22, May 24, May 29,
2023 2023 2023 2023
Albumin 3.77 (L) 2.54 (L) 3.82 3.14 (L) g/dL 3.8 - 5.1 g/dL Impaired liver function. Losses from
albuminuria.
Bilirubin
Results
Test Unit of Measurement Reference Value Implications
May 17, May 24, May 28, May 29,
2023 2023 2023 2023
Direct 7.2 (H) 4.75 (H) 4.2 (H) 3.38 (H) mg/dL 0.00 - 0.25 mg/dL Presence of biliary obstruction
Bilirubin
Indirect 1.40 (H) 1.1 (H) 1 0.82 mg/dL 0 - 1.0 mg/dL Presence of liver dysfunction
Bilirubin
Total Bilirubin 8.6 (H) 5.80 (H) 5.20 (H) 4.20 (H) mg/dL 0.2 - 1.3 mg/dL Presence of biliary obstruction
67
Amylase
Results
Test Unit of Reference Value Implications
May 17, 2023 May 24, 2023 Measurement
Amylase 90.00 33 U/L 30 -110 U/L Normal Range Amylase circulating in the blood
Electrolytes
Results
Test Unit of Reference Value Implications
May 17, May 18, May 22, May 23, May 24, May 28, May 29, Measurement
2023 2023 2023 2023 2023 2023 2023
Potassium 3.94 3.80 3.83 4.8 4.09 3.90 3.96 mmol/L 3.5 - 5.3 mmol/L Normal Range
Sodium 126.42 (L) 140.0 135.7 141.4 140.0 137.9 138.4 mmol/L 135 - 148 mmol/L Low sodium in blood circulation caused by
liver dysfunction.
Lipid Profile
Result
Test Unit of Reference Value Implications
May 20, 2023 Measurement
HDL-Cholesterol 15.00 (L) mg/dL 40 - 60 mg/dL Presence of high HDL- cholesterol caused by liver dysfunction
68
Liver Profile
Results
Test Reference Value Implications
May 17, 2023 May 24, 2023 May 29, 2023 Unit of
Measurement
S.G.O.T/AST 149.00 (H) 50.9 (H) 112.00 (H) U/L 17 - 59 U/L Liver Injury secondary to bile duct obstruction.
Alk. Phosphate 621.00 (H) 269.5 567 (H) U/L 80 - 306 U/L Presence of Biliary duct obstruction.
69
Interpretation:
Creatinine is a normal waste product that builds up in your blood from using your
muscles. Your body makes creatinine at a constant rate all the time, and healthy
kidneys remove almost all of this creatinine. By comparing the amount of creatinine in
your blood with a standard normal amount. A liver disease. Poor liver function interferes
with creatine production, which can cause low creatinine. Symptoms include jaundice,
abdominal pain and swelling which the patient manifested.
Low level of albumin happens when your body doesn’t produce enough of the
albumin protein, or when you lose too much albumin in your urine or stool. Your liver
makes albumin, which prevents fluid from leaking out of blood vessels into your tissues.
Albumin makes up 50% of the proteins found in your plasma. When your albumin levels
are low, hormones and other important compounds aren’t able to get to where they
need to go in your body to fulfill their duties. Low levels of albumin indicates that there
are infection or inflammation taking place that can signify our patient to have an
infection caused by his condition.
During our assessment patient X has an impaired liver function caused by biliary
obstruction which resulted in Hyperbilirubinemia. Higher levels of direct bilirubin in your
blood may indicate your liver isn't clearing bilirubin properly which indicates liver
damage. Higher levels of indirect bilirubin is manifested in our patient causing him to be
jaundiced.
Hyponatremia means that the sodium level in the blood is below normal. Your
body needs sodium for fluid balance, blood pressure control, as well as the nerves and
muscles. When the sodium level in your blood is too low, extra water goes into your
cells and makes them swell. On the 17th of May the patient's sodium level decreased
because of liver dysfunction.
70
there is damage or inflammation in the bile duct, which causes a leakage of Alkaline
Phosphatase, resulting in elevated Alkaline Phosphatase in the blood.
71
IMMUNOLOGY
Results Reference Implications
Test Values
May 17, 2023 May 22, 2023 May 29, 2023
C-Reactive Protein 199.0 (H) 93.7 (H) 14.6 (H) 1-3 Presence of high C-reactive protein caused by liver dysfunction.
APTT May 17, 2023 99.8 (H) 31.9 Increased APTT caused by liver dysfunction
seconds 23.4 - 38.5 seconds
May 20, 2023 48 (H) 36.8 Increased APTT caused by liver dysfunction
PROTHROMBIN TIME
Unit of Normal Range I.N.R. Implications
Test Date Result Control Measurement
Prothrombin Time May 18, 2023 35.9 (H) 14.2 seconds 11.0 - 16.0 2.5 Increased prothrombin time caused by liver dysfunction.
seconds
May 20, 2023 13.8 13.2 1.05 Normal Range
72
Interpretation:
A C-reactive protein (CRP) test determines the level of C-reactive protein in your
blood, which is a protein produced by your liver. In reaction to inflammation, your liver
secretes CRP into your circulation. These cells initiate an inflammatory response in
order to capture bacteria and other pathogens or to begin mending wounded tissue. As
a result, the patient had discomfort, swelling, bruising, or redness. However,
inflammation may also impact bodily systems that you cannot see, such as your joints.
73
PATHOPHYSIOLOGY
74
Choledochal cyst is a congenital cystic dilation of bile duct. The disease pathway
starts with two factors. Predisposing and Precipitating. Predisposing factors are due to
the patient’s race, age, gender, immune etiologies and congenital factors. According to
Alverson (2019), choledochal cyst is a congenital abnormality that causes abnormal
enlargement of bile duct. What precipitates his condition is his environment as he is
exposed to toxins or chemicals such as fertilizers and his hard labor lifestyle because
he helps his parents with hard work on their farm. His diet is also detrimental to his
condition consisting of coffee 3-4 times a day, cobra energy drink, softdrinks, junk foods,
high-fat cholesterol, fried,dried,salty and spicy foods and drinking untreated water with
scarcity of fruits and vegetables. Viral infection also precipitates the condition because
we do not know that the patient has been exposed to viral infection before that
contributes to his condition now. These factors mentioned contributed to the injury of the
lining of the bile duct that activates the inflammatory and immunologic response which
leads to the proliferation of biliary epithelial cells. When the biliary epithelial cells
proliferate, this increases the number of cell growth and cell division which then results
in the formation of cystic mass in the bile duct. In this case, a Computed Tomography
(CT) Scan was ordered and it was found that the mass measures 14.4x11.5x9.78cm
(April 17, 2023). The patient also underwent Magnetic Resonance
Cholangiopancreatography (MRCP) with contrast Magnetic Resonance Imaging (MRI)
that resulted with the measurement of approximately 11.6x13.1x17.3 cm (April 17,
2023). The mass is palpable at RUQ. The mass continues to enlarge which then
resulted to complete obstruction of lumen of the hepatic biliary tree that increases the
Alkaline Phosphatase (ALP) of 1143 U/L (N:80-306 U/L).
75
The formation of subsequent hyperactive growing fibrin scars results in damage
of the hepatocytes. Hepatocytes damage decreases the synthetic function that leads to
derangement in coagulation. In this case, this will then decreases the clotting factors
which shows abnormality in the lab results of: above normal Partial Thromboplastin
Time (PTT) of 35.9 (N:11.0-16.0) and Activated Partial Thromboplastin Time (APTT) of
99.8 (N:23.4-38.5). The result also shows below than normal: Red Blood Cells (RBC) of
4.13 (N:4.2-5.4), Hemoglobin (Hgb) of 9.80 g/dL (N:12-16 g/dL), Hematocrit (Hct) of
29.90% (N:37-47%), and Mean Corpuscular Hemoglobin (MCH) of 36.70 pg
(N:27-31pg). In this case, the patient was given Vitamin K 1 amp/10mL because this is
essential for the synthesis of several clotting factors. Due to these abnormal laboratory
results, the patient was given 2 Fresh Frozen Plasma (FFP) transfused on May 19,
2023 and 2 Packed Red Blood Cells (PRBC) transfused on days May 22 and 24, 2023.
Due to the blood transfusion, tha patient manifested fever with at temperature of 38.5C
and because of this, the patient was given Paracetamol 300mg IV q6 x4. Hepatocytes
damage also results to decrease in Albumin of 2.54 mg/dL (N: 3.8-5.1 mg/dL).
Abnormally high results of liver function tests also manifests due to hepatocytes
damage such as Aspartate Aminotransferase (AST) of 135.4 U/L (N:17-59), Alanine
Aminotransferase (ALT) of 60.20 U/L (N:0-42), and C-reactive protein of 199.0 (N:1-3).
The CT Scan and MRCP with contrast MRI mentioned above that showed
palpable mass at RUQ shows manifestation of indigestion, dyspepsia, restlessness,
diaphoresis, and nausea. These resulted in abdominal pain tenderness at RUQ that the
patient reported 8 out of 10 of pain scale. In line with this, the patient was given
Paracetamol 300 mg IV q6 x4. Due to the palpable mass at RUQ, the patient was
ordered to be NPO that contributed to his low BMI of 13.6 (N: <16.5). The NPO was
ordered for the preparation of the surgery on May 23, 2023 with the surgical procedure
of Excision of Choledochal Cyst Hepaticoduodenostomy, Drain, from 7:25AM-3:00PM.
The surgery was done and the cyst was successfully excised with a measurement of
approximately 19 cm in size. The final diagnosis of the patient is Choledochal Cyst Type
I.
76
IDEAL MEDICAL AND SURGICAL MANAGEMENT
MEDICAL MANAGEMENT
If the infection is brought on by gallstone disease, the doctor may initially advise painkillers
and antibiotics to treat the infection depending on the underlying reason. The numerous
causes of jaundice may usually be distinguished using diagnostic imaging and blood tests.
The etiology of the jaundice will determine the final course of action. The surgical procedure
of hepatocutaneous jejunostomy is simple, but it is imperative to construct a relatively straight
and short loop from the skin to the biliary-enteric anastomosis; choledochoscopy through a
redundant loop of small bowel is difficult, and access to the intrahepatic branches may be
impossible.
SURGICAL MANAGEMENT
Hepaticojejunostomy
The common bile duct, which drains bile into the duodenum, is often formed when the hepatic
duct joins the cystic duct, which transports bile from the gallbladder. Digestion becomes
difficult when a disease or injury to the biliary system prevents bile from flowing freely. To
guarantee that the bile from the liver readily drains into the intestine, a hepaticojejunostomy is
performed. Treatment options for ailments including benign strictures in the common bile duct
brought on by cysts, inflammation, and stones include a hepaticojejunostomy.
Hepaticoduodenostomy
The most commonly performed operations for biliary reconstruction after complete
surgical resection of choledochal cyst are Roux-en-Y hepaticojejunostomy or
hepaticoduodenostomy. The technique of hepaticoduodenostomy consisted of transection of
the common hepatic duct at the hilum with an incision extending approximately 5 mm along
the lateral wall of both the hepatic ducts to permit a wide anastomotic stoma.
77
Hepaticoduodenostomy is preferred by surgeons since it is a more physiological
procedure, is simpler to perform, and is associated with fewer complications such as adhesive
bowel obstruction, anastomotic leakage, and peptic ulcer as compared with Roux-en-Y
hepaticojejunostomy. Hepaticoduodenostomy requires less operative time, allows faster
recovery of bowel function, and produces fewer complications requiring reoperation.
Laparoscopic Cholecystectomy
Laparoscopic cystectomy has become a common procedure for choledochal cysts. The cyst
should be removed completely just above the confluence of the common biliopancreatic
channel at the distal end and approximately 5 mm from the confluence of the right and left
hepatic ducts at the proximal end to avoid complications of the cystic remnant. The operation
is feasible and safe. The rate of conversion to open surgery is low. The rate of complication
under skilled laparoscopic surgeons is also low, even lower than in open surgery.
Laparoscopic cholecystectomy takes about an hour or two. A surgeon will make a few small
incisions in your abdomen. The surgeon will insert thin, hollow tubes into those incisions. The
surgical team will then place a laparoscope and other surgical tools into the tubes. Your team
may pump carbon dioxide into your abdomen. This step inflates the surgical area and makes
it easier to see inside. Using the special tools, the surgeon will detach the gallbladder from the
78
rest of the body and remove it. The team will then close the incisions with stitches, surgical
clips or surgical glue.
Patient was brought to Northern Mindanao Medical Center for the Excision of
Choledochal Cyst last May 17, 2023. PNSS1L @ 25 gtts/min was started. Excision of
Choledochal Cyst, Hepaticojejunostomy was the requested surgery plan; however, it was later
altered to Excision of Choledochal Cyst, Hepaticoduodenostomy, Drain and was rescheduled
on May 23, 2023.
PRE-OPERATIVE
Condition of patient on departure to operating room, patient’s sensorium is awake GCS
is 15, reflexes are intact and pupils are reactive. Cardiovascular function rhythm is sinus.
Respiration is spontaneous, airway is patent, auscultatory is clear … Urine output is
adequate, blood replacement 1 unit PRBC. Neuromascular function is intact. Vital signs taken
as follows: BP 108/76 mmHg, PR 96 bpm, RR 20 cpm, Temp 36.8 C, sPO2 100%. Special
instructions is Morphine precaution.
INTRA-OPERATIVE
Secured consent signed by the Mother. Sign in time is 6:20 am, patient’s general status
is awake; conscious and coherent. With IVF lines PNSS 700cc level at Right arm regulated at
25 gtts/min. D5LR 300 cc level at the Left arm regulated at 20 gtts/min. Vital signs were: BP
110/70 mmHg, HR 118 bpm, RR 24 cpm, sPO2 99% with O2 4 lpm via mask. Induction of
anesthesia is general anesthesia, time started at 6:55 am and intubation time is 6:58 am. With
14 french foley catheter with return flow description of yellowish urine. Skin is prepped with
7.5% betadine cleanser site is Abdomen. Pre-Op counting is done and draping is also done.
Time out at exactly 7:20 am. Operation started at 7:25 am. C—arm is used and PNSS is used
for irrigation. Dressing is subcuticular and operation ended at exactly 3:00 pm. Extubation
time is 3:25 pm. Skin condition after removal had no signs of burns; dry and intact. Airway is
spontaneous. Patient is sedated but responsive to direct stimulus. IV lines are PNSS1L at 10
gtts/min and PLR at 30 gtts/min. Urine output is 200 ml, yellowish. Patients contraption are
FBC and JP Drain. Post-Op vital signs are as follows: BP 140/80 mmHg, PR 100 bpm, RR 18
cpm, sPO2 100%. Patient is then transferred by a stretcher at exactly 3:50 at the PACU .
Special endorsements: maintain patient on NPO, placed on MHBR with FBC attached to
Urobag.
On May 23, 2023 at 6:20 am, the patient was brought to the operating room. The
following were the actual step-by-step procedures that were performed to the patient:
1. The patient was placed in a supine position under general anesthesia.
2. Asepsis was antisepsis.
79
3. Drapes were placed.
4. At exactly 7:25 am, the surgery started. Cherney Incision was performed first.
5. Approximately 19 cm of choledochal cyst and a distended gallbladder were
found.
6. During the operation blood was transfused at around 12:00 PM. No passage to
duodenum.
7. Isolation of cyst (circumferential dissection and separation from Portal Vein and
Hepatic Artery).
8. Distal CBD dilated & united above pancreas level.
9. Proximal hepatic duct ligated.
10. Hepaticoduodenostomy was done and Jackson-Pratt drain was inserted.
11. Surgery ended at exactly 3:00 PM.
POST-OPERATIVE
Patient’s vital signs BP: 129/70, PR 97 bpm, RR 20 cpm, sPO2 100% Temp 36.0 C.
Patient is drowsy, Patients position at PACU is semi fowler with side rails up. IVF 1 is PLR1L
at Right arm and IVF 2 is PNSS1L at the Left arm. Oxygen support 4-6 lpm via face mask.
Monitoring devices are Pulse Oximeter, BP apparatus. Post op site at the abdomen dry and
intact. PostOp drain is JP, Urine FBC 100mL. Patient is transferred to ward at exactly 7:45
pm.The following medications were given to the patient: Morphine 2 mg IV q6; Paracetamol
300 mg IV q6 x4 ; Keterolac 15 mg IV q6 x 4 ; Piperacillin-Tazobactan 1.5 gm IV q8 ;
Metronidazole 300 mg IV q6.
After the operation the patient was still on NPO.The following medications were given to
the patient: Morphine 2 mg IV q6; Paracetamol 300 mg IV q6 x4 ; Keterolac 15 mg IV q6 x 4 ;
Piperacillin-Tazobactan 1.5 gm IV q8 ; Metronidazole 300 mg IV q6.
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DRUG STUDY #1
DRUG ORDER MECHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECTS OF THE DRUG NURSING RESPONSIBILITIES/
(Generic Name, ACTION PRECAUTIONS
Brand Name,
Classification,
Dosage, Route,
Frequency)
Generic Name: Paracetamol has a To relieve pain Hypersensitivity to its 1.It is important to note that pain assessment
paracetamol central analgesic effect components; liver CNS: agitation, anxiety, headache, should be performed regularly
that is mediated problems; kidney fatigue, insomnia. 2. Monitor the patient’s response to the
Brand Name: through activation of problems medication throughout the course of
Febrinil descending Resp: atelectasis, dyspnea. treatment to ensure that the
serotonergic pathways. medication is effectively managing the
Classification: To exert central actions patient’s pain and to make any
Analgesic which ultimately lead to CV: hypertension, hypotension. necessary adjustments to the dosage
the alleviation of pain or treatment plan.
Dosage: symptoms. GI: constipation, nausea (IV), 3. Advise patient to consult a health
300mg vomiting. care professional if discomfort or fever
is not relieved by routine doses of this
Timing: F and E: hypokalemia. drug or if fever is greater than 39.5 C
6am, 12nn, 6pm, or lasts longer than 3 days.
12mn GU: renal failure (high doses/chronic 4. Caution parents not to let the patient take other
medication containing paracetamol and they
use). should read the label of all other medication
Route:
Intravenous carefully to ensure that it does not contain
Hemat: neutropenia, pancytopenia. paracetamol.
5. Make sure the parent and the patient are aware
Frequency: that they must not exceed the recommended
q6 MS: muscle spasms, trismus.
dose to avoid overdose and further complications.
Derm: rash, urticaria.
81
DRUG STUDY #2
DRUG ORDER MECHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECTS OF THE DRUG NURSING RESPONSIBILITIES/
(Generic Name, ACTION PRECAUTIONS
Brand Name,
Classification,
Dosage, Route,
Frequency)
Generic Name: Piperacillin binds Perioperative Hypersensitivity to 1.Observe patient for signs and
piperacillin and to bacterial cell prophylactic agent penicillin’s, beta-lactams, CNS: SEIZURES (higher doses), symptoms of hypersensitivity (rash,
tazobactam wall membrane, cephalosporins, or pruritus, laryngeal edema, wheezing).
confusion, dizziness, headache,
causing cell tazobactam (cross Discontinue the drug and notify health
Brand Name: sensitivity may occur) insomnia, lethargy. care professional immediately if these
death. Spectrum
Pipcin occur.
is extended
Classification: compared with GI: diarrhea, constipation, 2. Monitor bowel function. Diarrhea,
penicillin antibiotic other penicillins. drug-induced hepatitis, nausea, abdominal cramping, fever, and bloody
Tazobactam is an stools should be reported to health care
Dosage: antibiotic of the vomiting. professional promptly.
1.5gms beta-lactamase
inhibitor class that GU: interstitial nephritis. 3. Instruct patient and significant other to
Timing: prevents the report rash, itching, or other signs of
4am, 12nn, 8pm breakdown of hypersensitivity immediately and report
Derm: rashes, urticaria. loose stools or diarrhea.
other antibiotics
Route:
Intravenous by 4. Inform parents that before they have any
Hemat: bleeding, leukopenia,
beta-lactamase medical tests, tell the doctor in charge
Frequency: enzyme neutropenia, thrombocytopenia. that your child is receiving this medicine.
q8 producing The results of some tests may be
organisms Local: pain, phlebitis at IV site. affected by this medicine.
82
83
DRUG STUDY #3
DRUG ORDER MECHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECTS OF THE NURSING RESPONSIBILITIES/
(Generic Name, ACTION DRUG PRECAUTIONS
Brand Name,
Classification,
Dosage, Route,
Frequency)
Generic Name: Disrupts DNA and Perioperative Prior history of hypersensitivity to CNS: SEIZURES, dizziness, 1. Monitor neurologic status during
metronidazole protein synthesis in prophylactic metronidazole or other headache, aseptic meningitis, and after IV infusions. Inform health
susceptible agent nitroimidazole derivatives. Use encephalopathy. care professional if numbness,
Brand Name: organism. with caution and reduce dose in paresthesia, weakness, ataxia, or
Antizoal therapeutic effect severe hepatic impairment. EENT: optic neuropathy seizures occur.
is bactericidal.
Classification: GI: abdominal pain, anorexia, 2. Monitor intake and output and daily
nitroimidazole nausea, diarrhea, dry mouth, furry weight, especially for patients on
antimicrobials tongue, glossitis, unpleasant taste, sodium restriction. Each 500mg of
vomiting. premixed injection for dilution
Dosage: contains 14 mEq of sodium.
300mg Derm: rash, urticaria; burning, mild
dryness, skin irritation, transient 3. If patient reports dry mouth,
Timing: redness. suggest ice chips or sugarless hard
6am, 12nn, 6pm, candy or gum; suggest a dental visit if
12mn Hemat: leukopenia. dryness lasts longer than 2 weeks.
84
DRUG STUDY #4
DRUG ORDER MECHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECTS OF THE NURSING RESPONSIBILITIES/
(Generic Name, ACTION DRUG PRECAUTIONS
Brand Name,
Classification,
Dosage, Route,
Frequency)
Generic Name: It works by stopping the For the management of Hypersensitivity; CV: Edema, fluid retention, 1. Assess pain (note type,
ketorolac body’s production of a pain Cross-sensitivity with other hypertension location, and intensity) prior to
substance that causes EENT: Laryngeal edema, and 1–2 hr following
NSAIDs may exist; stomatitis ENDO: Hyperglycemia
Brand Name: pain, fever, and Cerebrovascular bleeding; administration.
Pentolac inflammation. GI: Abdominal pain; acute
Advanced renal impairment pancreatitis; bloating; constipation;
diarrhea; diverticulitis; flatulence;
2. Frequently asses blood
Classification: or at risk for renal failure pressure (BP) during and after
due to volume depletion. GI bleeding, perforation, or
NSAID ulceration; hepatitis; hepatic administration and compare to
failure; jaundice; indigestion; normal values. because drug
Dosage: nausea; perforation of stomach or can lead to onset of
15mg intestines; vomiting; worsening of hypertension or worsen
inflammatory bowel disease existing hypertension.
Timing: GU: Interstitial nephritis, renal
4am, 12nn, 8pm failure, urine retention 3. Advise patient to report if
HEME: Agranulocytosis, anemia,
aplastic or hemolytic anemia,
rash, itching, visual
Route: Intravenous eosinophilia, leukopenia, disturbances, tinnitus,
pancytopenia, thrombocytopenia persistent headache, or fever
Frequency: RESP: Bronchospasm, pneumonia, occurs.
q8 x 3 cycle respiratory depression
85
DRUG STUDY #5
DRUG ORDER MECHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECTS OF THE NURSING RESPONSIBILITIES/
(Generic Name, ACTION DRUG PRECAUTIONS
Brand Name,
Classification,
Dosage, Route,
Frequency)
Generic Name: Binds to opiate For the management of Hypersensitivity; CNS: confusion, sedation, 1. Assess type, location, and
morphine receptors in the CNS. severe pain Acute or severe bronchial dizziness, dysphoria, euphoria, intensity of pain prior to and 1
Alters the perception asthma. Head trauma; floating feeling, hallucinations, hr following PO, subcut, IM,
Brand Name: of and response to increased intracranial headache, unusual dreams. and 20 min (peak) following IV
painful stimuli while pressure; administration.
Classification: producing generalized Severe renal, hepatic, or EENT: blurred vision, diplopia,
narcotic CNS depression. pulmonary disease. 2. Monitor blood pressure prior
miosis.
Therapeutic effect is to Hypothyroidism; Seizure to administration. Hold if
Dosage: decrease the severity disorder. systolic BP < 100 mm Hg or
2mg of pain. Resp: respiratory depression. 30 mm Hg below baseline.
Monitor for respiratory
Timing: depression and hypotension
6am, 12nn, 6pm, CV: hypotension, bradycardia. frequently up to 24 hours after
12mn administration of morphine.
GI: constipation, nausea,
Route: 33. May cause drowsiness or
Intravenous vomiting. dizziness. Caution patient to
call for assistance when
Frequency: GU: urinary retention. ambulating.
q6
4. Advise patient to change positions
Derm: flushing, itching, slowly to minimize orthostatic
sweating. hypotension.
86
DRUG STUDY #6
DRUG ORDER MECHANISM OF INDICATION CONTRAINDICATION ADVERSE EFFECTS OF THE NURSING RESPONSIBILITIES/
(Generic Name, ACTION DRUG PRECAUTIONS
Brand Name,
Classification,
Dosage, Route,
Frequency)
Generic Name: Require for hepatic The treatment of Impaired liver function, patients GI: gastric upset, unusual 1. Monitor pulse and BP
Vitamin K synthesis of blood coagulation disorders with hereditary taste. frequently; notify health care
coagulation factors. due to faulty formation of hypoprothrombinemia, renal professional immediately if
Brand Name: Therapeutic coagulation factors impairment, cases of over Derm: flushing, rash, urticaria. symptoms of internal bleeding
effectsare prevention caused by interference in anticoagulation due to heparins, or hypovolemic shock
Classification: of bleeding. Vitamin the activity of vitamin K. and hypersensitivity to vitamin develop.
fat soluble vitamin K helps to make K. Hemat: hemolytic anemia.
various proteins that 2. Monitor therapeutic
Dosage: are needed for blood Local: erythema, pain at effectiveness which is
1amp/10ml clotting and the indicated by shortened PT,
building of bones. injection site, swelling. INR, bleeding, and clotting
Timing: times, as well as decreased
4am, 12nn, 8pm Misc: allergic reactions, hemorrhagic tendencies.
3. Educate patient to
Route: hyperbilirubinemia (large maintain consistency in diet
Intravenous doses in very and avoid significant
increases in daily intake of
Frequency: vitamin K–rich foods when
q8 x 3 cycle premature infants), drug regimen is stabilized.
kernicterus. Know sources rich in vitamin
K: Asparagus, broccoli,
cabbage,
4. assist patient when
ambulating because dizziness
may occur.
87
NURSING MANAGEMENT
Preoperative Nursing Care Plans
Priority Problem #1: Impaired tissue perfusion related to blockage of bile duct as evidenced by low hemoglobin level
ASSESSMENT DATA NURSING DIAGNOSIS GOALS AND OBJECTIVES NURSING INTERVENTIONS AND RATIONALE EVALUATION
May 22, 2023 Impaired tissue perfusion related Short-term Goal: Independent: Goals are met.The patient was
to blockage of bile duct as ● After 2 hours of nursing ● Assess skin color, temperature, moisture, and able to identify individual risk
Subjective: evidenced by low hemoglobin intervention, the patient will whether changes are widespread or localized. factors affecting the condition.
● None level be able to identify individual Rationale: Helps in determining location and type The patient and family were able
risk factors affecting the of perfusion problem. to participate in prevention
Objective: condition. ● Measure capillary refill. measures and treatment
● Hgb 9.70 g/dL Long-term Goal: Rationale: To determine adequacy of systemic programs.
(N:12.0-16.0) ● After 6 hours of nursing circulation.
● MCH 26.60 pg intervention, the patient and ● Explain all procedures and treatments.
(N:27-31) family will be able to Rationale: Understanding expected events and
● WBC 12.44x10^3/uL participate in prevention sensations can help eliminate anxiety, associated
(N:5-10) measures and treatment with the unknown.
● Pallor programs. ● Provide knowledge on normal tissue perfusion
● Skin cool to touch and possible causes of impairment.
● Pale nail beds Rationale: Knowledge of causative factors provides
● Bipedal edema a rationale for treatments.
● Determine nutritional status and potential for
delayed healing or tissue injury exacerbated by
malnutrition.
Rationale: Proper nutrition aids in healing.
● Encourage early ambulation or mobilization as
tolerated.
Rationale: Promotes circulation and reduces risk
associated with mobility.
● Emphasize the need for regular medical and
laboratory follow-up.
Rationale: To evaluate disease status and
response to therapies.
Dependent:
● Administer fluids, electrolytes, and nutrients as
indicated.
Rationale: To promote optimal blood flow, organ
perfusion and function.
88
Priority Problem #2: Acute pain related to palpable mass at RUQ as evidenced by guarding behavior
ASSESSMENT DATA NURSING DIAGNOSIS GOALS AND OBJECTIVES NURSING INTERVENTIONS AND RATIONALE EVALUATION
Dependent:
1. Administer prescribed pain medications:
Rationale: To provide pain relief.
● paracetamol (Febrinil) 300 mg IVTT every 4
hours (4am-8am-12nn-4pm-8pm-12mn)
89
Priority Problem #3: Anxiety related to threat to change in health as evidenced by fear of complications of the outcome of the operation
ASSESSMENT DATA NURSING DIAGNOSIS GOALS AND OBJECTIVES NURSING INTERVENTIONS AND RATIONALE EVALUATION
90
Postoperative Nursing Care Plans
Priority Problem #1: Acute Pain related to surgical incision secondary to Excision of Choledochal Cyst and Hepaticoduodenostomy and
insertion of Jackson-Pratt (JP) drain (May 24 to 26, 2023)
ASSESSMENT DATA NURSING GOALS AND OBJECTIVES NURSING INTERVENTIONS AND RATIONALE EVALUATION
DIAGNOSIS
Acute Pain
Subjective: related to surgical Short-term Goals: Independent: Goals partially met:
incision
May 24, 2023 secondary to After 8 hours of nursing 1. Note type and location of incision and drainage. After 8 hours of nursing
● “Sakit kaayo ang kaning dapit sa gi Excision of interventions, the patient will: interventions the patient:
opera sa ako, mura ko og gidunggab Choledochal Cyst Rationale: Severe pain in either area should be
sa kasakit. Nag sige ko og mata
gabii, dili ko katulog og tarong tungod and ● verbalize pain within manageable investigated further for possible complications ● reported that pain was slightly
sa ka sakit,” as verbalized by the Hepaticoduodeno level and will report a decrease in relieved from a pain scale of
patient on the first postoperative day stomy and pain scale rating from 10/10 to 8/10 2.Perform and document a comprehensive 10/10 to 9/10(May 24, 2023)
● Pain scale 10/10; sharp stabbing pain insertion of ● participate in actions to decrease continuous pain assessment. Instruct patient in ● participated in actions to
felt at the right upper and lower Jackson-Pratt pain regular use of a (0–10 or similar) pain-rating scale. decrease pain and demonstrated
quadrants of the abdomen (JP) drain (May ● demonstrate proper use of adjunct Monitor pain scale rating at regular intervals. proper use of non-pharmacologic
24 to 26, 2023: comfort measures comfort measures such as
May 25, 2023
Postoperative Rationale: Assists in differentiating cause of pain and comfortable positioning and
Days 1 to 3) Long-term Goals: provides information about disease progression or splinting when moving and
● “Sakit pa gihapon akong tahi og kini
pud dapit sa drain nga nakasabit sa resolution, development of complications, and performing deep breathing
akong tiyan, wala pa gihapon ko’y After 3 days of nursing interventions, effectiveness of interventions.A standardized tool for exercises
tarong nga tulog,” as verbalized by the patient will: rating pain helps in assessment and management of
the patient on the second pain
postoperative day ● report that pain is decreased or After 3 days of nursing
● Pain scale 10/10; sharp pain felt at controlled through a decrease in 3. Regularly monitor and investigate if there are interventions, the patient:
the at the right upper and lower
pain scale rating from greater than reports of increased incisional pain and changes in
quadrants of the abdomen
5/10 to less than 5/10. characteristics of pain. ● reported that pain was
May 26, 2023 ● appear relaxed and able to rest controlled from a pain scale of
and sleep appropriately. Rationale: Deep, dull, aching pain in the operative area 10/10 to 4/10 (May 26, 2023)
● “Dili na kaayo sakit akong tahi pero ● demonstrate age-appropriate may indicate developing infection. ● appeared relaxed and got
sakit pa gihapon ni ang dapit sa drain blood pressure (BP), pulse, and uninterrupted longer sleep at
nga nakasabit sa akong tiyan,” as respiratory rates. 4. Position JP drain accordingly for optimal night
verbalized by the patient on the third ● manifest decreased or absence of function; making sure tubing is not kinked and is ●demonstrated normal vital signs:
postoperative day
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guarding behaviors, restlessness, free from clots or any obstructions. Secure the BP: 120/80 mmHg; PR: 62
● Pain scale 8/10; gnawing pain felt at and irritability. bulb to keep it from pulling on the skin or bpm; RR: 18 cpm
the at the right upper and lower ● demonstrate use of relaxation skills becoming dislodged. Drain accumulated fluid as ● did not manifest guarding
quadrants of the abdomen and diversional activities and on necessary. behaviors, was not restless,
● non-pharmacologic methods to control Rationale: Improper position, kinking, or accumulation was smiling and was not
● May 26, 2023 pain. of clots and fluid in the tubing changes the desired irritable anymore
● ● “Dili na kaayo sakit akong tahi ● participate in usual activities of daily negative pressure and impedes air or fluid evacuation ● demonstrated proper use of
pero sakit pa gihapon ni ang living (ADLs) within the level of ability
dapit sa drain nga nakasabit sa non-pharmacologic comfort
akong tiyan,” as verbalized by 5. Promote bedrest, allowing client to assume
measures such as comfortable
the patient on the third position of comfort
positioning and splinting and
postoperative day performing deep breathing
Rationale: Bedrest in low-Fowler’s position reduces exercises patient participating
intra-abdominal pressure; however, client will naturally in usual activities of daily living
assume the least painful position. (ADLs) such as ambulating,
brushing his teeth, and
6. Identify and provide essential adjuncts as combing his hair.
necessary.
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9.Teach and encourage use of behaviors such as
guided imagery, distractions, visualizations, and
deep breathing
Rationale: Rest and sleep are vital for healing and can
enhance coping with stress and discomfort.
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Collaborative:
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Priority Problem #2: Imbalanced nutrition less than body requirements related to medically restricted intake
ASSESSMENT DATA NURSING DIAGNOSIS GOALS AND OBJECTIVES NURSING INTERVENTIONS AND RATIONALE EVALUATION
Subjective: “Dili pa siya pakaonon sa Imbalanced nutrition less Short-term Goal: Independent: Goals were met:
doctor kay obserbahan pa siya kung than body requirements
pwede na tanggalon ang NGT drain related to medically After 8 hours of nursing 1. Evaluate abdomen, noting presence and character After 8 hours of nursing interventions,
sa iyahang ilong og basin mo suka restricted intake and interventions, the patient and of bowel sounds, abdominal distention, and reports the patient and SO:
pa,” as verbalized by the patient’s hypermetabolic state SO will: of nausea.
mother. (March 24, 2023)
Rationale: Gastric distention and intestinal atony are
● identify individual nutritional ● identified client’s individual
frequently present, resulting in reduced or absent bowel
Objective: needs. sounds. Return of bowel sounds and relief nutritional needs such as need for
● Oral restriction (nothing per ● verbalize understanding of adequate vitamins and minerals,
orem): May 23, 2023to May 27, nutritional needs. 2. Note passage of flatus. increased protein and caloric intake.
2023 ● plan a diet to meet nutritional ● verbalized understanding of
● With NGT for drainage needs and limit Rationale: Indicates reestablishment of bowel function. nutritional needs as evidenced by
attached gastrointestinal (GI) Lack of return of bowel sounds and function within 72 SO saying, “Dapat jud nako
● Mid-upper Arm Circumference disturbances. hours may indicate presence of complications. bantayan iyahang mga kinaon,
(MUAC): 21 cm luto-an permi og gulay,
● Weight- 36 kg , Height-163 cm Long-term Goal: 3. Monitor NG tube output. Note the presence of maningkamot makapalit og vitamins
vomiting and diarrhea.
, BMI- 13.6 kg/m2 (underweight) para niya, og bawalan na nako siya
● Pale and dry skin, cracked After 1 week of nursing mag sige og kaon og parat og
Rationale: Large amounts of gastric aspirant, or severe
lips, brittle and dry hair interventions, the patient will: vomiting and diarrhea, suggest bowel obstruction, halang.”
● Pale mucous membranes requiring further evaluation. ● participated in planning a diet to
● Sluggish and fatigued ● initiate behaviors and lifestyle meet nutritional needs and limit
● Poor muscle tone changes to regain and to 4. Evaluate client’s appetite. gastrointestinal (GI) disturbances by
● Weight loss of 5 kgs from 41 maintain appropriate weight identifying foods and nutrients that
kg (May 17, 2023) to 36 kg (May 27, ● ingest nutritionally adequate Rationale: Appetite may be suppressed because of are ideal for the patient's diet.
2023). diet for age, activity level, and altered taste, early satiety, meal-related cramping, or
metabolic demands. medications, or a combination of these factors. After 1 week of nursing interventions,
● report improved energy level the patient:
5. Determine client’s current nutritional status using
● demonstrate progress in
age-appropriate measurements, including weight and
tissue healing free of infection body build, strength, activity level, and sleep and rest ● exhibited good appetite and
● demonstrate progressive cycles. consumed full share of his meal
weight gain toward goal and when diet was shifted to soft diet
improve MUAC Rationale: Identifies individual nutritional needs and ● exhibited improved energy level,
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● experience no further signs of provides a comparative baseline. can tolerate walking and changing
malnutrition, with laboratory positions easier
values within normal range 6. Monitor client’s weight regularly. Evaluate weight ● demonstrated progress in tissue
in terms of premorbid weight. Compare serial weights healing, surgical incision and wound
and anthropometric measurements. remained dry and intact, free of
infection
Rationale: Indicator of nutritional needs and adequacy of ● did not gain weight but
intake. maintained his weight of 32 kgs.
MUAC remained at 21 cm. Note: He
7. Review client’s nutritional history, including food was still on his first day of being on
preferences and evaluate knowledge of nutrition. a soft diet
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Rationale: Including client in planning gives a sense of
control of the environment and may enhance intake.
Fulfilling cravings for desired food may also improve
intake.Previous dietary habits may be unsatisfactory in
meeting current needs for tissue regeneration and
healing.
Collaborative:
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Rationale: May be needed to reduce nausea or vomiting.
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Priority Problem #3: Impaired skin integrity related to postsurgical procedure and presence of Jackson-Pratt drain
ASSESSMENT DATA NURSING DIAGNOSIS GOALS AND OBJECTIVES NURSING INTERVENTIONS AND RATIONALE EVALUATION
Subjective: none Impaired skin integrity Short-term Goal: Independent: Goals were met:
related to postsurgical After 8 hours of nursing 1. Inspect incision and dressings. Note
Objective: procedure and presence interventions, the patient and SO characteristics of drainage from JP drain. Observe After 8 hours of nursing interventions,
● surgical incision at RUQ of Jackson-Pratt drain will: incision and drainage periodically, noting the patient and SO:
● JP drain at RLQ approximation of wound edges, hematoma
● Wound drainage: ● learn and demonstrate proper formation and resolution, and presence of redness, ● learned and demonstrated proper
Postop days 1-2: sanguineous techniques of wound/incision care. bleeding, and drainage. techniques of wound/incision care
Postop days 3-5: serosanguineous ● demonstrate behaviors that Rationale: Verifies status of healing, provides for early and the proper way to drain the
Postop day 6: serous reduce tension on suture line. detection of developing complications requiring prompt contents of the JP drain.
● identify and participate in evaluation and influencing choice of interventions. ● demonstrated behaviors that reduce
interventions to prevent and reduce tension on suture line such as
risk of infection. 2. Teach and promote proper hand hygiene such as splinting when moving.
proper handwashing. Maintain strict hand hygiene ● identified and participated in
Long-term Goal: measures, using soap and water or antibacterial interventions to prevent and reduce
After 1 week of nursing soaps, before and after client care. Institute infection risk of infection such as knowing the
interventions, the patient will: precaution. signs and symptoms to watch out for
● achieve timely wound healing Rationale: Hand hygiene remains the cornerstone of and report that may indicate infection
without complications infection prevention. and ways to prevent infection such as
● be free of signs of infection and handwashing and wound/incision
inflammation such as purulent 3. Provide routine incisional care, being careful to care.
drainage, erythema, and fever keep dressing dry and sterile.
Rationale: To promote wound healing and reduce After 1 week of nursing interventions
bacterial contamination and avoid infections. the patient’s incision and drainage site
remained dry, intact and free of signs of
4. Teach client and SO proper wound care and infection and inflammation as
dressing change. manifested by normal vital signs,
Rationale: Promotes competent self-care and serosanguineous/serous drainage,
independence in self-care, reducing risk of absence of erythema and fever.
complications.
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6. Emphasize to the client and SO not to touch the
incision and drain site.
Rationale: May cause infection.
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DISCHARGE PLAN
Goals:
1.Instruct patients to follow the entire course of prescribed medications according to the
doctor's order. Discontinuation of treatment may result potential complications
2.Instruct the patient on the importance of following the right dosage and timing of the
medications as prescribed.
3.Explain to the patient the purpose, indications and side/adverse effects of the
prescribed medications.Take pain medicine exactly as directed
Medications
1.) Take pain medicines exactly as directed., If the doctor gave you a prescription for
pain, take it as prescribed.
2.) If your doctor prescribed antibiotics, take them as directed. Do not stop taking
them just because you feel better. You need to take the full course of antibiotics.
Take Cefixime 500 mg/tab, 2x/day for 7 days; Metronidazole 500mg/tab, 3x/day
for 7 days; Celecoxib 200mg/cap, 2x/day for 7 days.
Environment
1. To reduce swelling and pain, put ice or a cold pack on your belly for 10 to 20 minutes
at a time. Do this every 1 to 2 hours. Put a thin cloth between the ice and your skin.
2. Keep the area clean and dry. You may cover it with a gauze bandage if it weeps or
rubs against clothing. Change the bandage every day.
Health Teachings
1. Health Teachings about daily wound dressing with emphasis of proper aseptic
technique on wound care and daily bath for hygienic purposes. Do not remove the
paper strips or cut any of the visible sutures.
2..Take your medicines exactly as directed. Use pain medicine as needed for easy
ambulation.
2. Provide the patient with the name and telephone number of the physician to call if a
question arises.
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3.Instructed the patient about the importance of regular check-up and for any follow up
visit to any health care provider to continuously assess the patient’s condition.
Diet
Emphasize to the patient to try the Dietary Patterns with Choledocal Cyst Diet including
Soft Food Diet with no colored food. Eat fewer refined carbohydrates and less sugar.
Eat healthy fats, like fish oil and olive oil, to help your gallbladder contract and empty on
a regular basis. Avoid unhealthy fats, like those often found in desserts and fried foods
Spirituality
Encouraged the client to attend mass if able. To thank God for all the things He provided
and pray to almighty God for guidance and healing.
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RESULTS AND DISCUSSION
Patient was last assessed on May 29, 2023, the patient was still admitted at the
hospital ready to be discharged. On May 30, 2023, the patient was discharged at 10:23
AM. There are significant changes in his condition. His vital signs on the last day of
assessment were the following: T- 36.5⁰C; P- 63 bpm; R- 20 cpm, BP- 110/80 mmHg,
Oxygen Saturation of 99% with tolerable abdominal pain with a pains cale rating of
4/10. Patient was ambulating and JP Drain was attached to the surgical site with
purulent discharges. Patient was eventually discharged from the hospital on May
30,2023 and was scheduled for a follow-up check up on June 7, 2023.
The authors were able to compare the actual and ideal nursing and medical
interventions. Based on the author’s study, there are various ideal medical management
that can be done to facilitate his complete recovery. Also, the researcher learned the
vital role of proper nutrition, diet and healthy lifestyle where this can prevent the
occurrence of Choledochal Cyst. Therefore, health teachings are of utmost
importance to prevent these complications.
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CONCLUSION
At the end of this case study, the researchers were able to outline the
physiological process of the disease, apply its medical management in the clinical
setting, and provide the optimum nursing management of patients with Choledochal
Cyst Type I to deliver the most efficient care for the patient.
104
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