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Lymphatic - 12
Lymphatic - 12
By
Amal Fares
Lymphatic Organs
Primary=central Thymus
Bone marrow
paracortex
Medulla
• Lighter in staining
• Less lymphocytes
• Formed of:
1. Medullary cords: irregular branching
cords of B- lymphocytes, plasma cells
2. Medullary sinuses: space between
medullary cords & trabeulae, lined with
endothelium & macrophages.
Lymph circulation
• Afferent lymphatic vessels
carry lymph to cortex.
• Lymph flow in one direction
• Lymph filtered in cortical
sinuses then medullary
sinuses.
• Come out by efferent
lympatic vessels through
hilum.
Functions of lymph nodes
1. Filter lymph.
2. Proliferation & production of lymphocytes.
3. Immunological functions: humoral & cell mediated
immunity.
Spleen
• Single intra-abdominal hemolymphatic
organ.
• Structure: formed of stroma & parenchyma.
just like the formation of lymph nodes
Stroma of spleen
• Stroma: 1-Capsule: rich in smooth muscle
thick covered with peritoneum
thick
2-Trabeculae: elastic fibers & sm ms
divide spleen into irregular compartments.
3-Reticular Network
• Parenchyma:
1-White Pulp= Malpighian corpuscles
2-Red Pulp:
a-Splenic Cords=billroth cord.
b-Blood Sinusoids
II_Parenchyma
Sructure, Spleen A-
White Pulp=
Lym.F=Malpighian C.
Peritonium, Capsule
Central Arterioles
A-Capsule
B-Trabeculae
B-Red Pulp
C-Reticular fs. Bl. Sinusoids
Splenic Cords
=Billroth C.
White pulp
(malpighian corpuscles)
• White in fresh section.
• Rounded lymphatic nodules.
• Formed of: 4 concentric zones arranged around the
central arteriole from
• inside outwards:
1. Thymus dependent zone.
2. Germinal center.
3. Follicular zone.
4. Marginal (periphral) zone.
White pulp
(malpighian corpuscles)
1. Thymus dependent zone= T- cells
2. Germinal center= activated B-cells,
plasmablasts, plasma cells & macrophages
3. Follicular zone= B- cells.
4. Marginal (periphral) zone= B&T lymphocytes
White & Red Pulp
Red Pulp
Marginal Zone
Central art.
Venous sinuses
Germinal
Center
Trabeculae
Marginal
Trabecular Vein Zone