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Pathophysiology MCQ with Answers Pdf

1. Hypertrophy of a muscle is due to

(A) Increase in number of cells

(B) Increase in size of cells
(C) Decrease in number of cells
(D) Abnormal shape of cells
Ans - B

2. Replacement of one epithelium by other is

(A) Metaplasia
(B) Hyperplasia
(C) Aplasia
(D) Atrophy
Ans - A

3. Most of the iron in RBCs is located in

(A) Ferritin
(B) Myoglobin
(C) Hemoglobin
(D) Cytochromes
Ans - C

4. In iron excess state, which should be avoided

(A) Vitamin C
(B) Vitamin E
(C) Folic acid
(D) Plant flavonoids
Ans – C

5. Pernicious anemia is a form of which class of anemia

(A) Macrocytic megaloblastic

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(B) Macrocytic non megaloblastic

(C) Microcytic hypochromic
(D) Microcytic normochromic
Ans - A

6. Sickle cell anemia is caused by replacement of glutamic acid in beta globin chain of Hb by

(A) Arginine
(B) Valine
(C) Histidine
(D) Leucine
Ans - B

7. Which part of the human body is affected in case of osteoporosis

(A) Colon
(B) Skin
(C) Bones
(D) Kidney
Ans - C

8. The shape of normal red blood cells is

(A) Spherical
(B) Sickle shape
(C) Crescent shape
(D) Disc shape
Ans - D

9. What diagnostic test can be used to determine GFR as well as glomerular damage
(A) Renal scan
(B) Urinalysis
(C) Intravenous pyelogram
(D) Creatinine clearance
Ans - D

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10. Erythropoietin promotes the synthesis of .............. in the bone marrow

(A) Monocytes
(B) Platelets
(C) Red blood cells
(D) Lymphocytes
Ans - C

11. The most common complication of rheumatoid arthritis is

(A) Loss of hair

(B) Amenorrhoea
(C) Carpal tunnel syndrome
(D) HIV
Ans - C

12. When the aetiology of a disease is unknown, the disease is said to be

(A) Idiopathic
(B) Chronic
(C) Acute
(D) Acquired
Ans - A

13. Gout is a disorder of

(A) Metabolism
(B) Catabolism
(C) The nervous system
(D) None of the Above
Ans - A

14. Destruction of red blood cells is called

(A) Phagocytes
(B) Leukaemia
(C) Haematrocrit

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(D) Haemolysis
Ans - D

15. Bilirubin is a waste product released during the breakdown of

(A) Mast cells

(B) RBCs
(C) WBCs
(D) Platelets
Ans - B

16. Jaundice is also known as

(A) Icterus
(B) Hemophilia
(C) Anemia
(D) Hypercholesterolemia
Ans - A

17. Anemia arises due to deficiency of

(A) Iron
(B) Vitamin B12
(C) Folic acid
(D) Any of the Above
Ans - D

18. IBD is inflammatory disorder of which part

(A) Liver
(B) Spleen
(C) Intestine
(D) Lung
Ans - C

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