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S YS T E M AT I C R E V I E W P R O T O C O L

Effectiveness of exercise interventions to prevent


shoulder injuries in athletes: a systematic review protocol
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Johannes Jacobus Wessel Swart 1  Benita Olivier 1,2


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1
Department of Physiotherapy, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa, 2The Wits-JBI Centre for
Evidenced-Based Practice: A JBI Affiliated Group, Johannesburg, South Africa

ABSTRACT

Objective: This review will evaluate the effectiveness of exercise intervention versus no intervention or alternate
intervention to prevent shoulder injuries in athletes.
Introduction: Injury-prevention research has proven the effectiveness of exercise in preventing sports injuries in
general and in the lower limb specifically. However, the results have been extrapolated to sport-related shoulder
injuries from limited evidence. Similar reviews have been faced with insufficient high-quality evidence and limited
studies due to restrictive target populations, resulting in reduced generalizability.
Inclusion criteria: Peer-reviewed randomized controlled trials, with adequate control arms, investigating shoulder-
injury events after exercise intervention in athletes, both training or competing in sports, will be included. Studies
with substitute end points for injury events and non-self-propelled athletes, or vehicle-assisted athletes, will be
excluded.
Methods: A comprehensive search of multiple databases will be used to find relevant studies. The databases will be
searched from inception to April 2021, with no language restrictions imposed. Keywords and derivatives of ‘‘sport,’’
‘‘exercise intervention,’’ ‘‘prevention,’’ ‘‘shoulder injury,’’ and ‘‘randomized controlled trials’’ will be used.
Sources will include Academic Search Ultimate (EBSCO), CINAHL Plus (EBSCO), Cochrane Central Register of
Controlled Trials (Wiley), MasterFILE Premier (EBSCO), MEDLINE (PubMed), Physiotherapy Evidence Database (PEDro),
ProQuest Health and Medical Complete and Nursing and Allied Health Source (ProQuest Complete), ScienceDirect
(Elsevier), Scopus (Elsevier), SPORTDiscus (EBSCO), and Web of Science (Clarivate Analytics). Data appraisal,
extraction, and synthesis will follow JBI guidance for systematic reviews of effectiveness.
Systematic review registration number: PROSPERO CRD42020204141
Keywords: exercise interventions; primary prevention; shoulder injury; systematic review
JBI Evid Synth 2021; 19(10):2847–2856.

Introduction swimmers.3 Shoulder injuries can cause significant


hysical activity can significantly and positively dysfunction and disability in sports with high recur-
P enhance health, with injury being the only real
adverse effect.1 Upper-limb injuries contribute up to
ring upper-limb loads.4 The high loads from excessive
repetitive shoulder rotary movements in sports like
21.4% of all injuries sustained during practice in a swimming, or the explosive shoulder actions found in
variety of team sports.2 The repetitive nature of some primary throwing sports, can result in injury.5
sports can result in higher incidences of shoulder The incidence of injury to the upper limb is
injuries in individual sports, with an incidence of up lower than that of the lower limb, which justifies
to 91% of shoulder injuries occurring in elite the disproportional amount of literature related to
lower-limb injury prevention.6,7 However, this
appears unjustified when comparing the evidence
Correspondence: Johannes Jacobus Wessel Swart, amassed in preventing a relatively rare condition,
jjwswart@gmail.com such as an anterior cruciate ligament injury (ACL).
The authors declare no conflict of interest. An ACL injury has an incident rate of 2.10 per 10,000
DOI: 10.11124/JBIES-20-00465 athletic exposures for contact sports and 0.36 per

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SYSTEMATIC REVIEW PROTOCOL J.J.W. Swart and B. Olivier

10,000 athletic exposures for non-contact sports8; population to overhead athletes. The primary aim
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even in high-risk sports only one out of 80 athletes was to identify and categorize the risk factors for
sustain an injury to the ACL.9 The limited research sustaining shoulder injuries. The secondary objective
resources spend on shoulder-injury prevention seems was to synthesize the evidence for the prevention of
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unfounded. There exists a clear need for a specific shoulder injury in overhead athletes. One relevant
review on shoulder-injury prevention.10 study matched the pre-planned inclusion criteria.18
Adult athletes experience an average burden of Potential studies investigating or including
injury of two weeks per season.11 In 45% of shoulder injuries have recently been published for
youth athletes, more than a week’s loss of training baseball,19 cricket pace bowlers,20 football,21,22
is due to injury.12 A resultant 65% reduction in the handball,23,24 tennis,25 and volleyball.26 Relevant
achievement of their performance goals occurs in articles can be included from specific sporting codes,
athletes who sustain more than one injury requiring which are regularly excluded due to limitations on
a modification of more than 20% of their seasonal the population or injury method (eg, Australian
training weeks.11 The impact of an injury on football).13 The recent influx of studies provides a
an athlete produces a physical, psychological, persuasive argument to investigate the feasibility of
performance, and financial fallout that requires producing a systematic review on shoulder injuries
management over several seasons.1,7,13 Prevention in sport.
is better than cure in breaking the chain reaction that High-quality systematic reviews propose
develops as a sequela of injury. strength training as superior or at least essential
In order to prevent sporting injuries, contemporary compared to all other components of injury-
research trends advocate primary-injury reduction prevention programs for injuries in general,
strategies, such as rule adaptation, neuro-muscular and to the lower limb specifically.9,14,27,28 The
training, and equipment modification for at-risk literature on whether or not exercise interventions
populations, particularly active youths and adoles- can reduce shoulder injuries and, if so, which
cents.1,7,12,14 These recommendations were developed specific elements of the program produce the
from a disproportional lower-limb research focus,6,15 proposed effect, is unclear.10 Current research
ignoring the unique characteristics of the lower extrapolation has substituted specific investigation
limb.4,5,10 This intense lower-limb focus is consistently into shoulder-injury prevention, resulting in some
defended from a utilitarian perspective2 using evidence studies reporting diverse findings when interven-
of the successful outcomes.16 Nevertheless, the risk tions are applied.5
and burden associated with shoulder injuries necessi- This review will have four aims. The main aim
tate a more specific and rigorous investigation.5,10 will be to summarize the available evidence on
A preliminary search of PROSPERO, MEDLINE, shoulder-injury prevention in sport. The second
the Cochrane Database of Systematic Reviews, and aim will be to provide estimates of acute injury
JBI Evidence Synthesis was conducted and no simi- versus overuse. The third aim will be to describe
lar systematic review on the topic was identified. A and categorize the different types of exercise inter-
systematic review from 2014 performed an analysis ventions found in the injury-prevention programs.
on which components of exercise-prevention pro- Exercises will be categorized into strength, stretching
grams prevented lower-limb injuries.17 Out of the 25 and flexibility, mobility, plyometrics, balance and
studies included, eight investigated ‘‘all injuries’’; proprioception, or multiple components.
however, no included study focused on the shoulder Furthermore, the final aim will be to describe and
specifically, and very few contained specific upper- categorize the components of shoulder-exercise-
limb exercises. Additional evidence is required to intervention programs into open kinematic chain
endorse the generalizability of exercise effectiveness exercises versus closed kinematic chain exercises.
to reduce shoulder injuries, as inferred in the studies To the authors’ knowledge, no meta-analysis on the
evaluating ‘‘all injuries.’’ effectiveness of exercise to prevent shoulder injury
The shoulder was explicitly targeted in a 2018 exists. Producing a meta-analysis will enable new
systematic review.10 This review investigated and thought-provoking information, furthering
shoulder injury risk factors and prevention in recommendations for prospective studies in the
overhead sports. The study limited the inclusion field.

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SYSTEMATIC REVIEW PROTOCOL J.J.W. Swart and B. Olivier

Review question of exercise. Exercise will be defined as: ‘‘a potential


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What is the effectiveness of exercise intervention disruption to homeostasis by muscle activity that is
versus no intervention or alternate intervention in either exclusively, or in combination, concentric,
the prevention of shoulder injury in athletes? eccentric or isometric.’’31(p.459)
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Inclusion criteria Comparator


Participants This review will consider studies that compare the
This review will consider all studies that include intervention to either a pure passive control group
human athletes participating in any sports forms, receiving no interventions (eg, regular training, usual
irrespective of sex, age, ethnicity, setting, geographi- practice, or no additional training) or an active
cal location, or level of skill. Study participants are control arm receiving alternate forms of intervention
typically healthy and free of injury at the start of (eg, other programs, technique feedback, supple-
injury-prevention studies; however, in order to mentation, equipment inclusion, or adaptation of
investigate acute injury versus overuse (chronic) assistive devices).
data, the inclusion of both injured and uninjured
participants is necessary. An athlete with an overuse Outcomes
index injury regularly continues to participate and The primary outcome measure of interest is shoulder
can partake in exercise interventions to prevent injury or pain, as defined by the authors. Similarly,
secondary injuries, which can be either recurring the definitions provided for the outcome measures
or subsequent injuries during a season. Non-self- in each individual study will be applied.10 In circum-
propelled or vehicle-assisted sports will be excluded stances where the injury definition is ambiguous, this
due to the high levels of damage sustained from study will define an injury according to the definition
collisions. Collision injuries have no bearing on of the International Olympic Committee: ‘‘Injury
the biomechanical and neuromuscular adaptations is tissue damage or other derangement of normal
that exercise intervention is purported to facilitate. physical function due to participation in sports,
Sport will be defined according to PubMed’s resulting from the rapid or repetitive transfer of
medical subject headings (MeSH): ‘‘Activities or kinetic energy.’’32(p.374)
games, usually involving physical effort or skill. The injury rates and relative risk (RR) will be
Reasons for engagement in sports include pleasure, calculated using the number of injuries, odds ratios
competition, or financial reward.’’29(para.5) As (OR), rate ratios (rr), hazard ratios (HR), and incident
athletes compete in sport, the definition will rate ratio (IRR) reported in the studies or calculated
provide absolute clarity if the definition of sport using STATISTICA (Statsoft, Tulsa, OK), based on
is ambiguous. A summary definition from the raw data provided in the included studies. An injury
literature is presented for an athlete: An athlete of the shoulder area will include injuries of the
must train to improve performance and results; rotator cuff, clavicle, scapula, and the proximal biceps
participate actively in competitions while formally tendon.32 Research in injury prevention regularly
registered; and devote a considerable amount of reports injuries in an upper- and lower-extremity
time to the endeavor.30 split. A subgroup analysis of upper-extremity injuries
will be performed in addition if the data permits.
Interventions Secondary outcomes will include providing acute
This study will consider literature that assesses the versus overuse data (according to each study’s
effectiveness of all exercise interventions aimed at definition) estimates, if feasible. An overuse injury
preventing injury to the shoulder. All types of exercise is defined as repetitive micro-trauma over multiple
intervention will be included and grouped primarily events that may have either a gradual or sudden onset,
into six categories: i) strength, ii) stretching and while a singular sudden traumatic event results in
flexibility, iii) mobility, iv) plyometrics, v) balance acute injuries.32,33 Secondly, the aim will be to
and proprioception, or vi) multiple components of describe and categorize the different types of exercise
exercise. interventions found in injury-prevention programs,
An exercise intervention will be included if it mainly: strength, stretching and flexibility, mobility,
conforms with and corresponds to the definition plyometrics, balance and proprioception, or multiple

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SYSTEMATIC REVIEW PROTOCOL J.J.W. Swart and B. Olivier

components of exercise. Thirdly, we will describe Thirdly, the bibliography of critically appraised
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and categorize the components of the intervention articles selected for inclusion will be scrutinized
program’s shoulder-specific exercises into a closed for further studies.
or open kinematic chain, in order to establish an All databases will be searched from inception to
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overview of current prevention programs for the April 2021, with an updated search to be performed
sporting shoulder. near the end of the review. All RCTs contained in the
previous reviews will be included if they comply with
Types of studies the inclusion criteria.10,17,27 The databases to be
All randomized controlled trials (RCTs) will be searched from inception up until April 2021 include:
eligible for consideration. Studies measuring con- CINAHL Complete (EBSCO), Cochrane Central
trolled clinical outcomes (eg, shoulder strength) will Register of Controlled Trials (Wiley), MEDLINE
be excluded. Quasi-experimental studies and obser- (PubMed), Physiotherapy Evidence Database
vational studies will only be included in the absence (PEDro), ProQuest Health and Medical Complete
of RCTs on the subject matter. The decision to and Nursing and Allied Health Source (ProQuest
include only RCTs is based on the concern that Complete), ScienceDirect (Elsevier), Scopus (Elsevier),
studies with a high risk of bias can intensify bias SPORTDiscus (EBSCO), and Web of Science
if pooled rather than reduce it.34 (Clarivate Analytics). Source of unpublished studies
and gray literature will include Academic Search
Methods Ultimate (EBSCO) and MasterFILE Premier (EBSCO).
This protocol has been registered in PROSPERO Published and unpublished literature in all
(CRD42020204141). JBI methodology will be languages will be considered, and the relevant articles
followed for conducting a systematic review of effec- in languages other than English will be translated.
tiveness.35 The design will incorporate the frame-
work as per the Preferred Reporting Items for Study selection
Systematic Reviews and Meta-Analyses (PRISMA) Following the search, all identified citations will be
statement.36 Protocol amendments will be dated, collated and uploaded into EndNote v.9.3 (Clarivate
will include an explanation of the alteration, and Analytics, PA, USA) and duplicates removed. Two
will provide a rationale. independent reviewers will then screen the titles and
the abstracts against the inclusion criteria for the
Search strategy review. Potentially relevant studies will be retrieved
A three-step sequential strategy will be used to dis- in full and their citation details imported into the JBI
cover the relevant studies. The search process will be System for the Unified Management, Assessment
designed and implemented to uncover published and and Review of Information (JBI SUMARI; JBI,
unpublished studies. Firstly, a restricted investigative Adelaide, Australia).37
search in MEDLINE (PubMed) will be performed The full text of selected citations will be assessed
using the keywords ‘‘shoulder injury,’’ ‘‘primary in detail against the inclusion criteria by two inde-
prevention,’’ and ‘‘exercise intervention.’’ The initial pendent reviewers. Reasons for exclusion of full-text
search will enable the investigation into which text studies that do not meet the inclusion criteria will be
words and index terms are required to develop recorded and reported in the systematic review. Any
a comprehensive search strategy for MEDLINE disagreements between the reviewers at any stage of
(PubMed). the study selection process will be resolved through
The literature search will be designed to include discussion or via arbitration by a third reviewer.
both MeSH terms and text words. Search terms from The results of the search will be reported in full
similar reviews will be screened to determine the in the final systematic review and presented in a
completeness of the strategy.8,9 The second search Preferred Reporting Items for Systematic Reviews
will be expansive and employ all the identified and Meta-analyses (PRISMA) flow diagram.36
keywords and index terms contained in a fully devel-
oped search strategy with the adaptations required Assessment of methodological quality
by each specific database. The search procedure for Two independent reviewers will critically appraise
MEDLINE (PubMed) is attached (Appendix I). the selected studies. The methodological quality

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SYSTEMATIC REVIEW PROTOCOL J.J.W. Swart and B. Olivier

will be assessed after inclusion in the review. The different cluster adjustment methods; performing
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standardized JBI critical appraisal checklist for synthesis utilizing different statistical models, meth-
randomized controlled trials will be utilized for ods, and effect measures; and assessing the inclusion
RCTs and the JBI critical appraisal checklist of methodological quality of studies included. The
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for quasi-experimental studies will be used if non- testing will ascertain if similarity exists regarding the
randomized experimental studies require inclusion.35 effect magnitude and direction.
If a disagreement arises between the reviewers, a The standard Cochran’s Q and its P value, together
discussion will be held to resolve the dispute by con- with the x2 statistical assessments, will identify statis-
sensus. If no agreement can be reached, the decision of tical heterogeneity. The I2 and t2 statistical tests
a third independent reviewer will be final. will quantify the heterogeneity. The thresholds for
In the case of missing, incomplete, or ambiguous heterogeneity will be classified as unimportant (0 to
data, the authors of the study will be contacted by 40%), moderate (30% to 60%), substantial (50% to
email for clarification. The results of the critical 90%), and considerable (75% to 100%).40 The lower
appraisal will be reported in narrative form and a the P value of the heterogeneity, the more significant
table. All studies, regardless of the results of their the clinical heterogeneity (keeping in mind that the
methodological quality, will undergo data extraction P-value’s significance is set at 0.1 due to the statistical
and synthesis. test’s low power).41
The performance of sub-group analysis will be
Data extraction executed as the broad topic is expected to produce
A two-reviewer, independent data-extraction pro- high levels of inconsistency, requiring the identifica-
cess will be applied, and a table based on the stan- tion of the clinical or methodological sources of
dardized data extraction tool from JBI SUMARI will heterogeneity.42 Subgroups will enable the compari-
be used. The retrieved data will include the details son of the effects in the following pre-planned groups:
relating to population demographics, type of inter- shoulder injuries/upper-extremity injuries; acute/
vention and characteristics, primary and secondary overuse shoulder injuries; shoulder specific/non-
outcome measures, and the critical appraisal rating specific programs; upper/lower-extremity-dominant
(Appendix II). sports; and RCTs/cluster RCTs. Shoulder-specific
In the case of missing, incomplete, or ambiguous programs are deemed such if the applicable study
data, the authors of the study will be contacted by provides a statement to that effect or the program
email for clarification. Any disagreements between includes four or more shoulder-targeted exercises.
the reviewers will be resolved through discussion or Lower-extremity-dominant sports require the lower
by arbitration of a third reviewer. limb for the majority of sport-specific maneuvers
and skills.
Data synthesis Analytical examinations will be done using a
The rationale is to pool quantitative data for a fixed-effect model if there are less than five studies
statistical meta-analysis using JBI SUMARI. If included and a random-effects model if there are five
pooling is not possible, a narrative method will be or more studies included.39 A funnel plot will be
applied to represent the data using tables and created in STATA v.16 (StataCorp. 2019, LLC,
graphs. Effect sizes for categorical data will be Texas) to assess publication bias and tested by funnel
reported as RR and continuous data as standardized plot asymmetry, where suitable, using the Egger,
mean differences. Relative risk is intuitively Begg, or Harbord statistical tests. A funnel plot will
interpreted and enables greater access for a layper- not be performed for less than 10 studies.39 A
son, as OR may be challenging to understand.38,39 double-data-entry methodology will be utilized to
The confidence intervals will be calculated at 95% reduce errors.
for analysis of the effect sizes.
Sensitivity analysis will be performed to investi- Assessing certainty in the findings
gate the robustness of the results and the influence The Grading of Recommendations, Assessment,
that variances in study design, statistical methods, Development, and Evaluation (GRADE) approach
and methodology have on the effect estimates. for grading the certainty of evidence will be followed.
Analyses will be performed testing the inclusion of A Summary of Findings (SoF) will be created using

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SYSTEMATIC REVIEW PROTOCOL J.J.W. Swart and B. Olivier

GRADEPro (McMaster University, ON, Canada).43 10. Asker M, Brooke HL, Walden M, Tranaeus U, Johansson F,
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The SoF will present the following information where Skillgate E, et al. Risk factors for, and prevention of, shoulder
appropriate: estimates of relative risk with injury injuries in overhead sports: a systematic review with best-
incidence and a ranking of the quality of the evidence evidence synthesis. Br J Sports Med 2018;52(20):1312–9.
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11. Raysmith B, Drew M. Performance success or failure is


based on the risk of bias, directness, heterogeneity,
explained by weeks lost to injury and illness in elite Austra-
precision, and risk of publication bias of the
lian track and field athletes: a 5-year prospective study. J Sci
review results. Med Sport 2016;19(10):778–83.
12. Emery CA, Roy TO, Whittaker JL, Nettel-Aguirre A, van
Acknowledgments Mechelen W. Neuromuscular training injury prevention
This review will contribute to a masters of science strategies in youth sport: a systematic review and meta-
degree through the University of Witwatersrand for analysis. Br J Sports Med 2015;49(13):865–70.
13. Finch CF, Gray SE, Akram M, Donaldson A, Lloyd DG, Cook JL.
JS. The Faculty of Health Sciences has reviewed the
Controlled ecological evaluation of an implemented exer-
protocol, and an ethical clearance waiver has been
cise-training programme to prevent lower limb injuries in
applied for from the University of the Witwaters- sport: population-level trends in hospital-treated injuries. Br
rand’s Human Research Ethics Committee (HREC). J Sports Med 2019;53(8):487–92.
NM is the second independent reviewer. 14. Leppänen M, Aaltonen S, Parkkari J, Heinonen A, Kujala UM.
Interventions to prevent sports related injuries: a systematic
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SYSTEMATIC REVIEW PROTOCOL J.J.W. Swart and B. Olivier

Appendix I: Search strategy


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MEDLINE (PubMed)

Search conducted on 05/02/2021, retrieving 883 results


1AWnYQp/IlQrHD3i3D0OdRyi7TvSFl4Cf3VC4/OAVpDDa8KKGKV0Ymy+78= on 07/12/2023

Records
Search Query retrieved
#1 ‘‘athlete’’[Text Word] OR ‘‘Competition’’[Text Word] OR ‘‘contest’’[Text Word] OR 1,693,772
‘‘exercis’’[Text Word] OR ‘‘Game’’[Text Word] OR ‘‘Handball’’[Text Word] OR ‘‘javelin
throw’’[Text Word] OR ‘‘Judo’’[Text Word] OR ‘‘Karate’’[Text Word] OR ‘‘kung fu’’[Text
Word] OR ‘‘overhead’’[Text Word] OR ‘‘physical activit’’[Text Word] OR ‘‘physical
exercis’’[Text Word] OR ‘‘pitcher’’[Text Word] OR ‘‘recreation’’[Text Word] OR ‘‘Soft-
ball’’[Text Word] OR ‘‘sport’’[Text Word] OR ‘‘tae kwon do’’[Text Word] OR ‘‘taekwondo’’
[Text Word] OR ‘‘throw’’[Text Word] OR (‘‘Track’’[Text Word] AND ‘‘field’’[Text Word]) OR
‘‘train’’[Text Word] OR ‘‘triathl’’[Text Word] OR ‘‘Workout’’[Text Word] OR ‘‘wres-
tling’’[Text Word] OR ‘‘athletes’’[MeSH Terms] OR ‘‘athletic performance’’[MeSH Terms] OR
‘‘baseball’’[MeSH Terms] OR ‘‘basketball’’[MeSH Terms] OR ‘‘water sports’’[MeSH Terms] OR
‘‘cricket sport’’[MeSH Terms] OR ‘‘exercise’’[MeSH Terms] OR ‘‘exercise movement
techniques’’[MeSH Terms] OR ‘‘track and field’’[MeSH Terms] OR ‘‘football’’[MeSH Terms]
OR ‘‘games, recreational’’[MeSH Terms] OR ‘‘golf’’[MeSH Terms] OR ‘‘gymnastics’’[MeSH
Terms] OR ‘‘hockey’’[MeSH Terms] OR ‘‘water sports’’[MeSH Terms] OR ‘‘martial arts’’[MeSH
Terms] OR ‘‘motion’’[MeSH Terms] OR ‘‘motor activity’’[MeSH Terms] OR ‘‘movement’’
[MeSH Terms] OR ‘‘basketball’’[MeSH Terms] OR ‘‘para athletes’’[MeSH Terms] OR
‘‘exercise’’[MeSH Terms] OR ‘‘physical exertion’’[MeSH Terms] OR ‘‘physical fitness’’[MeSH
Terms] OR ‘‘water sports’’[MeSH Terms] OR ‘‘racquet sports’’[MeSH Terms] OR ‘‘recrea-
tion’’[MeSH Terms] OR ‘‘water sports’’[MeSH Terms] OR ‘‘soccer’’[MeSH Terms] OR
‘‘sports’’[MeSH Terms] OR ‘‘sports for persons with disabilities’’[MeSH Terms] OR ‘‘sports
medicine’’[MeSH Terms] OR ‘‘swimming’’[MeSH Terms] OR ‘‘tennis’’[MeSH Terms] OR
‘‘volleyball’’[MeSH Terms] OR ‘‘water sports’’[MeSH Terms] OR ‘‘wrestling’’[MeSH Terms] OR
‘‘youth sports’’[MeSH Terms]
#2 ‘‘balance exercise’’[Text Word] OR ‘‘calisthenic’’[Text Word] OR ‘‘exercise interven- 819,392
tion’’[Text Word] OR ‘‘Flexibility’’[Text Word] OR ‘‘intervenion’’[Text Word] OR ‘‘isome-
tic’’[Text Word] OR ‘‘isotonic’’[Text Word] OR ‘‘neuromuscular program’’[Text Word] OR
‘‘neuromuscular training’’[Text Word] OR ‘‘NMT’’[Text Word] OR ‘‘range of motion’’[Text
Word] OR ‘‘strength training’’[Text Word] OR ‘‘stretch’’[Text Word] OR ‘‘body weight’’
[MeSH Terms] OR ‘‘circuit based exercise’’[MeSH Terms] OR ‘‘exercise therapy’’[MeSH
Terms] OR ‘‘muscle strength’’[MeSH Terms] OR ‘‘muscle stretching exercises’’[MeSH Terms]
OR ‘‘proprioception’’[MeSH Terms] OR ‘‘range of motion, articular’’[MeSH Terms] OR
‘‘resistance training’’[MeSH Terms] OR ‘‘yoga’’[MeSH Terms]
#3 ‘‘incidence’’[Text Word] OR ‘‘injury rate’’[Text Word] OR ‘‘prehab’’[Text Word] OR 7,763,175
‘‘prevent’’[Text Word] OR ‘‘Prevention’’[Text Word] OR (‘‘Prevention’’[Text Word] AND
‘‘control’’[Text Word]) OR ‘‘prevention program’’[Text Word] OR ‘‘prevention proto-
col’’[Text Word] OR ‘‘Prophylaxis’’[Text Word] OR ‘‘reduc’’[Text Word] OR ‘‘risk’’[Text
Word] OR (‘‘accident prevention’’[MeSH Terms] OR ‘‘incidence’’[MeSH Terms] OR (‘‘preven-
tion and control’’[MeSH Subheading] AND ‘‘prevention and control’’[MeSH Subheading])
OR ‘‘primary prevention’’[MeSH Terms] OR ‘‘program evaluation’’[MeSH Terms] OR ‘‘risk
assessment’’[MeSH Terms] OR ‘‘risk management’’[MeSH Terms]) OR ‘‘risk reduction
behavior’’[MeSH Terms]

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(Continued)
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Records
Search Query retrieved
1AWnYQp/IlQrHD3i3D0OdRyi7TvSFl4Cf3VC4/OAVpDDa8KKGKV0Ymy+78= on 07/12/2023

#4 ‘‘dislocation’’[Text Word] OR ‘‘fracture’’[Text Word] OR ‘‘Glenohumeral’’[Text Word] OR 6,835,834


‘‘Gleno-humeral’’[Text Word] OR ‘‘injur’’[Text Word] OR ‘‘instab’’[Text Word] OR ‘‘joint
instabilit’’[Text Word] OR ‘‘pain’’[Text Word] OR ‘‘problem’’[Text Word] OR ((‘‘range of
motion, articular’’[MeSH Terms] OR (‘‘range’’[All Fields] AND ‘‘motion’’[All Fields] AND
‘‘articular’’[All Fields]) OR ‘‘articular range of motion’’[All Fields] OR (‘‘range’’[All Fields]
AND ‘‘motion’’[All Fields]) OR ‘‘range of motion’’[All Fields]) AND ‘‘subluxation’’[Text
Word]) OR ‘‘shoulder fracture’’[Text Word] OR ‘‘shoulder impingement syndrome’’[Text
Word] OR ‘‘shoulder injur’’[Text Word] OR ‘‘shoulder pain’’[Text Word] OR ‘‘shoul-
der’’[Text Word] OR ‘‘strain’’[Text Word] OR ‘‘syndrom’’[Text Word] OR ‘‘trauma’’[Text
Word] OR ‘‘upper limb’’[Text Word] OR (‘‘accidents’’[MeSH Terms] OR ‘‘acromioclavicular
joint’’[MeSH Terms] OR ‘‘athletic injuries’’[MeSH Terms] OR ‘‘cumulative trauma disor-
ders’’[MeSH Terms] OR ‘‘fractures, bone’’[MeSH Terms] OR ‘‘fractures, cartilage’’[MeSH
Terms] OR ‘‘joint instability’’[MeSH Terms] OR ‘‘musculoskeletal system’’[MeSH Terms] OR
‘‘pathology’’[MeSH Terms] OR ‘‘rotator cuff’’[MeSH Terms] OR ‘‘rotator cuff injuries’’[MeSH
Terms] OR ‘‘scapula’’[MeSH Terms] OR ‘‘shoulder dislocation’’[MeSH Terms] OR ‘‘shoulder
fractures’’[MeSH Terms] OR ‘‘shoulder impingement syndrome’’[MeSH Terms] OR ‘‘shoulder
injuries’’[MeSH Terms] OR ‘‘shoulder joint’’[MeSH Terms] OR ‘‘shoulder pain’’[MeSH Terms]
OR ‘‘shoulder injuries’’[MeSH Terms] OR ‘‘soft tissue injuries’’[MeSH Terms] OR ‘‘sprains
and strains’’[MeSH Terms] OR ‘‘tendon injuries’’[MeSH Terms] OR ‘‘tendons’’[MeSH Terms]
OR ‘‘upper extremity’’[MeSH Terms]) OR ‘‘wounds and injuries’’[MeSH Terms]
#5 ‘‘collar bone’’[Text Word] OR ‘‘Glenohumeral’’[Text Word] OR ‘‘Gleno-humeral’’[Text Word] 256,787
OR ‘‘shoulder’’[Text Word] OR ‘‘upper limb’’[Text Word] OR ‘‘acromioclavicular join-
t’’[MeSH Terms] OR ‘‘rotator cuff’’[MeSH Terms] OR ‘‘shoulder joint’’[MeSH Terms] OR
‘‘upper extremity’’[MeSH Terms] OR ‘‘clavicle’’[MeSH Terms]
#6 ‘‘randomized controlled trial’’[Text word] OR ‘‘randomised controlled trial’’[Text word] OR 761,572
‘‘randomized clinical trial’’[Text Word] OR ‘‘randomised clinical trial’’[Text Word] OR
‘‘randomized controlled trial’’[Publication Type]
#7 #1 AND #2 AND #3 AND #4 AND #5 AND #6 883
No language or date limits.

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SYSTEMATIC REVIEW PROTOCOL J.J.W. Swart and B. Olivier

Appendix II: Data extraction instrument


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First author’s last name


1AWnYQp/IlQrHD3i3D0OdRyi7TvSFl4Cf3VC4/OAVpDDa8KKGKV0Ymy+78= on 07/12/2023

Publication year
Appraisal rating
Country
Setting
 Sport
 Level
Participants
 Sex
 Age
Sample
 Sample size
 Drop-out rate
 Sample analyzed
 ITT/PP analysis
 Cluster adjusted
Intervention
 Name or description
 Type
 Frequency
 Dose
 Compliance
 Categorization
 OKC vs CKC
Outcome measures
 Shoulder or upper extremity
 Number of injuries (INV vs CON)
 Acute versus overuse
 Primary outcome
Bias and main limitations
CKC, closed kinematic chain; CON, control group; INV, intervention group; ITT, intention to treat; OKC, open kinematic chain; PP, per protocol

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