Wilson's disease

Wilson’s disease is a rare genetic disease that causes copper to build up in the liver, brain,
and vital organs. The majority of people with Wilson’s disease are between 5 and 35 years
.old, but it can affect those younger or older than that as well

Copper has a key role in nerve growth, healthy bones, collagen production and melanin
pigmentation in the skin. In normal cases, copper is absorbed from the food you eat, and the
body gets rid of excess amounts of it by means of a substance made in the liver (biliary
juicer)

However, in the case of people with Wilson’s disease, the body does not get rid of copper as
it is supposed and therefore accumulates copper in quantities that may pose a risk to the life
of the patient. Early diagnosis of Wilson’s disease helps treat it, and many people with the
.disease live completely normal lives

:Symptoms *

Wilson’s disease has been present from birth, but signs and symptoms do not appear until
copper accumulates in the brain, liver, or other organ. Signs and symptoms vary based on
:which parts of the body have been affected by the disease. It can include the following

Fatigue, poor appetite, or abdominal pain ..1

Yellowing of the skin and whitening of the eye (larvae) ..2

Cornea change color to golden brown (Kaizer-Fleisher rings) . .3

Accumulation of fluid in the legs or abdomen ..4

The Problems with speech, swallowing, or physical coordination .5

Lack of movement control or muscle stiffness ..6

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?When do you visit the doctor *

 An appointment should be made with a doctor if worrying signs and symptoms appear,
.especially if a family member has Whistula

Wilson’s disease is genetically transmitted with a recessive somatic chromosomal imper,

meaning that to get sick, only one copy of the defective gene must be inherited from both
parents. If you only receive one gay gene, you won’t get sick but will still hold the gene and
.can pass it on to your children

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Risk Factors: Risk Factors *

Your risk of Wilson’s disease may increase if your parents or relatives get sick. Ask your
doctor if you should have a genetic test to detect whether or not you have Wilson’s disease.
.The earlier the condition is diagnosed, the greater the chances of successful treatment

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:Multipliers*
Scarring of the liver (cirrhosis) ..1

Liver failure ..2

Ongoing neurological problems . .3

Kidney problems ..4

The Psychological problems .5

Blood problems ..6