Care Pathway On Extravasation Management

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Oncology Nursing Care Pathways

Care Pathways on Extravasation Management

1. Suspected extravasation/ classical extravasation 2. Immediate action:


if
 Patient complaints of burning or stinging  Stop the injection or infusion
sensation  Withdraw as much of the drug possible using
 There is evidence of swelling, induration, leakage wheel fashion with 16 gauge needle (use
at insertion site single needle for each aspiration)
 There is resistance on plunger of syringe or  Elevate the arm
absence of free flow of infusion, or  Inform the treating Physician

3. Remove Cannula

Extravasated
molecule is
DNA Binding DNA binding / Non DNA binding
Non-DNA
binding

4. a) Vesicant or Irritant 4. a) Vesicant or Irritant


Localize and neutralize Disperse and Dilute
Agents: Agents:

 Anthracyclines  Vinka alkaloids


 Antibiotics (Mitomycin/  Taxanes
Dactinomycin)  Platin salts
 Alkylating agents

4.a) Localize 4. a) Disperse

Apply dry cold pack( on and off) for 20 Apply dry hot fomentation(On and Off
mins 4 times daily for 48 hrs application) for 20 mins 4 times daily for
48 hrs
(Avoid alcohol compress)

4.a) Neutralize 4.a) Dilute


Use specific antidotes Administer agents increasing resorption

Anthracyclines  Vinka alkaloids


Apply:  Taxanes
 Topical DMSO  Platin salts
 Inj Dexamethasone
Infiltrate with Inj Hyaluronidase 1500 IU
Mitomycin C
Apply:
 Topical DMSO

Document the incident

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