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P-TF20-I Tubular Heat Exchanger Operation

The P-TF20-I Tubular Heat Exchanger is a Tube in Tube heat exchanger consisting
of two concentric tubes. The product flows through the inner tube while the service flows
through the space between the two tubes.
In Pharmaceutical line the tube in tube heat exchangers are designed in accordance with the
recommendations set by the FDA. The finished meet the highest standards, with certified
roughness if required. The design ensures drain ability and product recovery.
APPLICATIONS
Hot and cold purified water (PW) and distilled water is used for injection (WFI) products .
Hot Purified water is used in the preparation of all medication containing water except
ampoules, injections, some official external preparations such as liniments.
In the pharmaceutical industry today there is a requirement for a high quality sanitary heat
exchanger for point of use cooling with no risk of contamination between the product and the
cooling media. Tube in tube heat exchanger has been developed especially to meet this need.
ADVANTAGES OF TUBULAR HEAT EXCHANGER
 LOW MAINTENANCE COSTS
 HIGH WORKING PRESSURES AND TEMPERATURES
 EASY INSPECTION AND DISASSEMBLY
 HIGH SECURITY IN ASEPTIC PROCESSES
 EASY TO ENLARGE
 ADVANTAGES OF CORRUGATION
 HYGIENIC PROFILE
 DIFFERENT CORRUGATION GEOMETRIES
(HARD/SOFT/PLAIN)
 TURBULENT FLOW (LOWER REYNOLDS NUMBER THAN FOR SMOOTH
TUBES)
 HIGHER HEAT TRANSFER COEFFICIENTS
 AND LOWER EXCHANGE AREA
 HOMOGENEOUS THERMAL TREATMENT
 LOWER FOULING
 SHORTER RESIDENCE TIMES
 LONGER RUNNING TIMES

For higher design pressures or temperatures as well as hazardous fluids, the heat
exchangers can be checked according to AD 2000 Merkblätt, ASME VIII Div.1, PD
5500, EN13445 or by Finite Elements Analysis and CE certificated by individual
inspection modules.

PHARMACEUTICAL LINE TF20-I


INNER TUBE (Diameter) 52 mm
OUTER TUBE (Diameter) 70 mm
Mass flow rate : 1-6 kg/sec
Nominal length 6000 mm
Design temperature 180 ºC
Design pressure 10 bar
Double-pipe heat interchanger

In a liquid-to-liquid heat interchanger, the fluid to be heated is passed only once through the tubes
before it is discharged, i.e. single pass.

The heat transfer in this case is not efficient. In a double-pipe heat interchanger number of passes
can be increased as desired.

Construction:

In this case two pipes are used – one is inserted into the other. Cold fluid is passed through the inner
tube. The outer pipe acts as a jacket for the circulation of hot fluid. All jacketed sections are
interconnected.

Normally the number of pipe-sections are few. The length of the pipe is also less. The inner tubes
may be made of glass and standard iron. The pipes are connected with standard return bends and
the pipes are stacked vertically. The pipes may have longitudinal fins on its outer surface for better
heat transfer.

Working:

The hot liquid is pumped into the jacketed section. It is circulated through the annular spaces
between them and carried from one section to the next section. Finally it leaves the jacket. In this
process the pipes get heated.

The liquid to be heated is pumped through the inlet of the inner tube. The liquid gets heated up and
flows through the bend tube into the next tube-section and finally leaves the exchanger.

Limitation:

Double-pipe heat interchanger is economical when the heating surface area is less than 9 m2.

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