UNI PARQN- 71921302 -ORGANIC CHEMISTRY-II

1 1 1 Write an example for tertiaryalkyl halides ?

1 1 2 Explain the nature of C-X bond
1 1 3 How is alkyl halide prepared from alcohols?
1 1 4 Write the reaction of alcohol with PCl5
1 1 5 Notes on action of thionylchloride with alcohols.
Complete the reaction
1 1 6 CH2=CH2 HI
1 1 7 What is SN1 reaction?
1 1 8 Write any two physical propeties of alkyl halides
1 1 9 What is nucleophilic substitution reaction?
1 1 10 What are the factors affecting the nucleophilic substitution reaction?
1 1 11 Define the role of leaving group in SN2 reaction
1 1 12 How many steps are involved in SN1 and SN2 reactions?
1 1 13 Write any two reactions of alkyl halides
1 1 14 What are the different classes of nucleophiles?
1 1 15 Which is the better leaving group in nucleophilic substitution? -NH2 or -OH
Complete the following reaction
1 1 16 CuCl
Ar-N2

The following reaction does not take place. Why?

X

1 1 17 -OH

1 1 18 Can bezyne be trapped?

1 1 19 Define an organometallic reagent
1 1 20 State whether organometallic reagents are electrophilic or nucleophilic
1 2 1 Write any three methods of prepartaion of alkyl halides?
1 2 2 Explain physical properties and bond natures of alkyl halides
1 2 3 Write notes on nucleophiles and their role in substitition reaction
1 2 4 How solvent nature affect the nucleophilic substitition reaction?
1 2 5 Is Leaving group playing any role in nucleophilic substitition reaction? Explain
1 2 6 Explain the SN1 reaction with example
1 2 7 Write notes on SN2 reaction
1 2 8 How aryl halides are prepared?
1 2 9 What are the reagents not reacting with aryl halides? Why?
1 2 10 Write any three applications of Grignard reagent?
1 3 1 Write notes on chemical properties of alkylhalides.
1 3 2 Explain the various factors affecting nucleophilic substitution reaction
What are the different types of nucleophilic substitution reaction? Explain with
1 3 3
suitable examples.
1 3 4 Compare the elimination reaction with substitution reaction-explain
How arylhalides are prepared? Why arylhalides not undergoing nucleophlic
1 3 5
substitution reaction?
1 3 6 Explain various aromatic electrophilic substitutions reactions.
1 3 7 Explain in detail, SNAr mechanism
1 3 8 Write any two preparation methods and applications of Grignard reagent.
1 3 9 What are the syntheic applications of “Gilman reagent”
1 3 10 Explain organolithium reagent prepartions and applications?
2 1 1 How alcohols are classified?
2 1 2 Give example for 3o alochols

OH OH

2 1 3 CH CH2 CH CH3
H3C C H3C C
H H2

Give the IUPAC & common name of the following compunds

2 1 4 What is Hydrolysis ? give example
2 1 5 How to prepare alcohol from esters?
Complete the reaction
H2
2 1 6 C CH2
NaBH4
OHC C
H
2 1 7 How to prove the acidic character of alcohols?
2 1 8 Write dehydration reaction with example
2 1 9 Define Satzeff’s Rule with example.
2 1 10 How to prepare esters from alcohols?
2 1 11 What are the products of Oxidation of alcohols?
2 1 12 Can 3o alcohols be oxidized?
2 1 13 Write Physical properties of alcohols
2 1 14 Draw the trihydric alcohol strcture
2 1 15 What are the products of oxidation of glycol and glycerol
2 1 16 How to Classify monohydric alcohols
2 1 17 Write the Oxidation reaction of lead tetra acetate.
2 1 18 Draw the phenol structure
2 1 19 Write any one prepartion of Phenols
2 1 20 What is an epoxide? Give example?
2 2 1 Write any three methods of prepartaion of alcohols?
2 2 2 Explain physical properties and acidic nature of alcohols?
2 2 3 Explain the Classification of alcohols
2 2 4 Write the mechanism of Bouvaelt-Blanc reaction.
2 2 5 Write notes on reduction of carbonyl compounds
2 2 6 Write few reactions involving cleavage of O-H bond
2 2 7 Give some oxidated products of alcohols
2 2 8 Give brief notes on dihydric alcohols
2 2 9 Write Reimer–Tiemann reaction with mechanism
2 2 10 What is Kolbe’s–Schmidt Reaction? Explain with mechanism.
2 3 1 Expalin in detail about the prepartaion of alcohols?
Brief the following reactions with mechanism i) Fries and ii) Claisen
2 3 2
rearrangements
Give detailed notes on classification, physical properties and acidic nature of
2 3 3
alcohols
2 3 4 Write notes on reduction and oxidation of alcohols
2 3 5 Write Reimer–Tiemann and Kolbe’s–Schmidt reaction with mechanism
Complete OHthe following reactions OH

iii
i i) NaOH/CH3I i) Br2/H2O

2 3 6 OH OH
iv
ii
i) NaOH/CH3COOCOCH3 i) AlCl3/CH3COOCOCH3

Predict the products with mechanism

O

OH
O R
2 3 7 ii
i i) NaOH/CHCl3
i) Lewis acid

How are ethers prepared by Williamson synthesis? Write any two chemical reactions of
2 3 8
ethers.
Write notes on following ether reactions 1. Zeisel method
2 3 9 2. Acid and base catalyzed ring opening
3. Action of hydroiodic acid

2 3 10 Discuss the mechanism of Pinacol-Pinacolone reaction.

3 1 1 What is the hybridization of carbon in carbonyl group?
Write the IUPAC name of the following compunds
Br CHO
3 1 2
CH
H3C CHO

3 1 3 Give general mechanism of nucleophillic addition reactions of Aldehydes

Complete the reaction
O
3 1 4 CH3CH2OH

Cu
Complete the reaction RCH2OH
300 oC
3 1 5

3 1 6 How to synthesis Aldehydes from Catalytic dehydrogenation of alcohols

3 1 7 Define ozonolysis? Give example
3 1 8 What is Rosenmund’s Reduction?
3 1 9 How is aldehyde protected by 1,3-dithane?
3 1 10 Write addition of Grignard reagents to carbonyl compounds
3 1 11 Write Meerwein-Ponndorf-verely (MPV) reduction
3 1 12 Write the Clemmensen reduction
3 1 13 Write the Sommelet’s Reaction
3 1 14 Write notes on Reimer Tiemann Reaction
3 1 15 Write notes on Water solubility of aldehydes and ketones
3 1 16 What are the factors
Why aromatic favoured
carbonyl the reactivity
compounds are less of nucleophillic
reactive than theaddition ?
corresponding
3 1 17 aliphatic carbonyl compounds?
3 1 18 Write the equation of Addition of hydrogen cyanide to carbonyl compounds
3 1 19 How terminal alkynes added to aldehydes ?
3 1 20 Draw the structure of 2, 4-dinitrophenyl hydrazine
 Write the structure of the carbonyl group and explain IUPAC Name of carbonyl
3 2 1
compounds with suitable example
Write brief notes on acids and bases catalysed nucleophillic addition reactions of
3 2 2
Aldehydes
Write notes on i) Rosenmund’s Reduction? ii) Synthesis of aldehyde from 1,3-
3 2 3
dithane
3 2 4 Explain Addition of Grignard reagents with Mechanism
3 2 5 Explain the Meerwein-Ponndorf-verely (MPV) reduction with Mechanism?
3 2 6 Explain Clemmensen reduction with mechanism?
3 2 7 Write any three prepartion of carbonyl compounds
3 2 8 Write any three prepartion of aromatic aldehydes
3 2 9 Write notes on Gattermann Koch aldehyde synthesis
3 2 10 Explain in detail Gattermann aldehyde synthesis
3 3 1 Write detailed note on prepartion and properties of carbonyl compounds.
3 3 2 What are the Preparative methods of aromatic aldehydes available explain?
Brief the following reactions with Mechanism i) Wolff-Kishner reduction ii)
3 3 3
Haloform reaction iii) Cannizaro reaction
How to prepare following compounds from carbonyl compounds i) Hydrozones ii)
3 3 4
phenyl hydrazones iii) 2, 4 dinitrophenyl hydrazones iv) semicarbazides
Write notes on i) Rosenmund’s Reduction? ii) Synthesis of aldehyde from 1,3-
3 3 5
dithane and iii) Addition of Grignard reagents with Mechanism
Explain the following naming reactions i) Gattermann Koch aldehyde synthesis ii)
3 3 6
Gattermann aldehyde synthesis iii) Clemmensen reduction with mechanism
Write notes on following reactions with Mechanism i) Meerwein-Ponndorf-verely
3 3 7
(MPV) reduction, ii) Clemmensen reduction
3 3 8 Brief the oxidation reactions of aldehydes in detail
Wrtite notes on following reactions with Mechanism i) Cannizaro reaction and ii)
3 3 9
Reformatsky reaction
Explain the following reactions and give mechanism for any one reaction (i) Perkin
3 3 10
reaction (ii) Beckmann and (iii) Benzil-Benzilic acid rearrangement
4 1 1 Define Carboxylic acids and give examples
4 1 2 Define ethers? Give examples
Give the IUPAC & common of the following compunds
C H OC H
4 1 3 CH3OCH3 CH3OCH2CH3 6 5 2 5

4 1 4 How to prepare ethers?

Complete the reaction
H3 C
O

4 1 5 Heat
CH3I

4 1 6 Define epoxides ? Give examples

4 1 7 How to synthesis epoxides?
4 1 8 Write the order of the acidity of acetic acid and their halogen derivatives
4 1 9 Why para nitrobenzoic acid stronger than para toluic acid?
 Write the IUPAC & common name of the following compounds
H COOH H COOH

4 1 10 i) ii)
H COOH HOOC H

4 1 11 What is the product when toluene is heated with KMnO4 ? Write the equation.
4 1 12 How to synthesis terephthalic acid?
4 1 13 Write Koch reaction
4 1 14 How to prepare carboxylic acid using Grignard’s reagents
4 1 15 Write the equation of hydrolysis of acid anhydride?
4 1 16 How to convert amide to acid?
4 1 17 What is Hunsdiecker reaction?
4 1 18 Write the reaction of carboxylic acids with metals
4 1 19 What is kolbes reaction?
4 1 20 Write the equation of Carboxylic acids reaction with PCl 5
4 2 1 Explain Structures, bonding and physical properties of Carboxylic acids
4 2 2 Explain Fries rearrangement with mechanism.
How is acidity of carboxylic acid affected by electron withdrawing and electron
4 2 3
releasing group?
4 2 4 Explain reaction Mechanisms of Aldol condensation.
4 2 5 Write the Benzoin condensation with mechanism
4 2 6 Brief notes on Knoevenagel condensation with mechanism
4 2 7 Write the Claisen-Schmidt condensation with mechanism
4 2 8 Explain the reaction and mechanism of Beckmann rearrangement.
4 2 9 Write a short note on Wittig reaction
4 2 10 Write note on effect of substituent’s on acidity of carboxylic acids
4 3 1 Write detailed note Dieckmann reaction.
4 3 2 Explain Nomenclature, Synthesis and chemical reactions of epoxides.
4 3 3 Explain the Reformatsky reaction with mechanism
4 3 4 Write the Claisen-Schmidt and Perkin condensation with mechanism
4 3 5 Write in detail on Knoevenagel condensation with mechanism.
4 3 6 Give four different methods to prepare carboxylic acids
4 3 7 Explain nomenclature, synthesis of carboxylic acid
4 3 8 Explain α-Halogenation of aliphatic acids with mechanism
4 3 9 Write any five chemical reactions of carboxylic acid?
4 3 10 Write decarboxylation of carboxylic acid with suitable mechanism.
5 1 1 Define thiols? Give two examples?
5 1 2 Give IUPAC Names of i) CH3SH ii) CH3CH2CH3SH iii) CH3CH2CH3S CH3
5 1 3 How to prepare ethanethiol from ethyl iodide?
Complete the reaction
KSH
5 1 4 CH3CH2I

5 1 5 How to prepare ethanethiol from thiourea?

 Complete the reaction
NH2

5 1 6 CH3CH2Br
S NH2

5 1 7 How to synthesis thiols using Grignard reactions?

5 1 8 How to convert ethanol to ethanethiol?
Complete the reaction
5 1 9 CH3CH2OH H2S

5 1 10 Write the equation of hydrogen sulphide addition to alkenes?

5 1 11 How to prepare 2-propanethiols?
Complete the reaction
H2SO4
5 1 12 CH3CH=CH2 HSH

5 1 13 Write physical properties of thiols with examples?

5 1 14 Write the reaction of thiols with acids and acid halides.
5 1 15 Write the reaction of aldehydes and ketones with thiols?
5 1 16 What is the role of thiols in proteins?
5 1 17 How to prepare diethyl sulphide?
5 1 18 Write the structure of dimethyl sulphone.
5 1 19 Define sulphonic acid? Give examples.
5 1 20 How to prepare ethanesulphonic acid?
Write the notes on nomenclature and physical properties and any two methods to
5 2 1
synthesis of thiols
Complete the following reactions KSH
NH2

CH3CH2Br CH3CH2I

S NH2

5 2 2
H2SO4
CH3CH=CH2 HSH

5 2 3 Write notes on oxidation of thiols?

Write the notes on nomenclature and physical properties and any two methods to
5 2 4
synthesis of thioethers?
5 2 5 Write notes on mustard gas reaction and properties
5 2 6 Write any three chemical reactions of thiols
5 2 7 Write any three chemical reactions of thioethers
5 2 8 Write a brief note on preparation of thioether.
5 2 9 How to prepare benzenesulphonic acid?
5 2 10 Write any three chemical reactions of thiosulphonic acids
5 3 1 Briefly explain the nomenclature with examples and methods to synthesise thiols
5 3 2 Write notes on
on i)
physical properties andii)any four with
chemical
Write notes Oxidation of thiols? Thiols acidsreactions
and acid of thiols iii)
halides
5 3 3 Thiols with
Account on aldehydes and ketones
nomenclature, physical properties and methods to synthesis of
5 3 4 thioethers
5 3 5 Write notes on note
physical
Write detailed on i)properties
Oxidationand any four chemical
of thioethers reactions
ii) Mustard of thioand
gas reaction ethers
5 3 6 properties
Define sulphonic acid with examples? Methods for the prepartion of alkylsulphonic
5 3 7 acids and benzene sulphonic acid?
5 3 8 Write notes on reaction of benzene sulphonic acid.
5 3 9 Explain in detail about the application of Thiols in daily life.
5 3 10 Write in detail on the application of Sulphonic acids in detergents.