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All About Asthma Triggers singlesFinal2A
All About Asthma Triggers singlesFinal2A
• For allergic rhinitis and/or bronchial asthma egg, shell sh, tree nuts & peanuts are
associated with immediate onset
• Milk, chocolate, wheat, citrus and food colourings are associated with delayed onset
• Maintain low humidity at home.
• Keep indoor air clean; change lters in furnace and air conditioner. Consider
installing a small-particle lter in your ventilation system. Keep dust to a minimum.
Reduce dust that can aggravate nighttime symptoms by adjusting certain items in your
child's bedroom. For example, encase pillows, mattresses and box springs in dustproof
covers. Consider removing carpeting and installing hard ooring in your home,
particularly in your child's bedroom. Use washable curtains and blinds.
• Clean regularly. Clean your home at least once a week to remove dust and allergens.
• Reduce your child's exposure to cold air. If your child's asthma is worsened by cold,
dry air, wearing a face mask outside can help.
• Reduce pet dander. If your child is allergic to dander, it's best to avoid pets with fur or
feathers. If you have pets, regularly bathing or grooming them also might reduce the
amount of dander. Keep pets out of your child's room.
• Use your air conditioner. Air conditioning helps reduce the amount of airborne pollen
from trees, grasses and weeds that nds its way indoors. Air conditioning also lowers
indoor humidity and can reduce your child's exposure to dust mites.
• After coming inside from outdoors, shower right away, wash hands and face
• Leave pollen covered clothes at the door and change right away
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All About
Asthma
Triggers
A PRACTICAL GUIDE FOR HEALTH CARE PROVIDERS
Contents
Introduction 1
Work-Related Asthma 16
Special Considerations 34
Bibliography 38
Authors
The Lung Association would like to thank the following authors
for their contribution to the development of this resource.
Reviewers
The Lung Association gratefully acknowledges the
following people who reviewed the booklet.
This book has been endorsed by The Lung Association’s medical societies,
the Ontario Thoracic Society (OTS) and the Ontario Respiratory Care Society (ORCS).
Introduction
All About Asthma Triggers was written by health care providers for health care providers. The idea for this guide started when
a group of asthma educators, working in the Primary Care Asthma Program (PCAP), identified a need for a practical resource to
quickly identify potential triggers and to help their patients with asthma learn how to avoid and/or limit exposures. Subsequently,
a needs assessment revealed that other health care providers, working in many different settings, often feel overwhelmed by the
amount of information available and need a better way to consolidate information and make recommendations based on the best
available evidence. We have done that for you.
This guide is intended to provide you with a quick reference for trigger identification and management, enabling you to help
your patient identify possible irritants and allergens that could be contributing factors. Irritants are inhaled substances that irritate
the airways, causing asthma symptoms, but do not cause an allergic reaction. Examples of irritants include smoke, chemical fumes
and cold air. Allergens are inhaled substances that cause an allergic reaction. Examples of allergens are pollens, animal dander and
mould. Repeated exposure over a long period of time is often necessary before asthma symptoms occur in response to an allergen.
Once you and your patient have identified potential triggers, you will be able to recommend some ways to avoid or limit
exposure. It is important that these avoidance strategies complement appropriate medication use in each individual patient, with
a goal to achieve optimal asthma control. In some cases this will be only a start and you will need to refer your patient to a specialist
or specialty centre for more testing and advice.
This booklet is organized so information about common triggers (irritants and allergens) that are found across settings is
presented first, followed by information about triggers found in specific settings such as schools, workplaces and farms/ranches.
The final section includes more general information for your consideration. All of the information must be applied based on the
needs and goals of the patient, as well as the specific needs of the health care provider and practice setting. This guide should
be used as a tool to assist in decision-making for patient care, while ensuring that appropriate supports are in place to provide
the best care possible. Medical information and evidence are constantly changing. As new research and experience broaden our
knowledge, changes in asthma management will be necessary and appropriate.
Disclaimer:
The content of this guide is based on current available evidence and has been reviewed by medical experts. It is provided for infor-
mational purposes only. The information is general in nature and is not intended to be a substitute for sound clinical judgment.
Seek the advice and expertise of other qualified health care providers with any questions you may have about specific patient care.
1 All About Asthma Triggers - A Practical Guide For Health Care Providers
Common Asthma Triggers
2 All About Asthma Triggers - A Practical Guide For Health Care Providers
Common Asthma Triggers
Cockroaches (Allergen)
Common insects that can be found Allergen is found in decaying • Remove garbage from kitchens
anywhere in the home, school or work- cockroach body parts and feces and bathrooms.
place. They thrive in wet areas, where mostly in kitchens and bathrooms, • Clean up all food crumbs or
food waste has not been removed. especially near: taps, water pipes, spilled liquids immediately.
They are common in inner city areas. cupboards, appliances, toilets, • Wash dishes, cooking equipment
garbage containers and cardboard. and counters promptly after use.
• Keep counters, sinks, tables and
floors clean and clear of debris.
• Seal cracks and openings around
or inside cabinets.
• Store garbage in covered containers.
• Employ professional eradication service.
Dust (Irritant)
Indoor dust, unlike outdoor dust, Dust is found almost everywhere Note: Dust and dust mites cannot be totally
consists of a combination of materials. indoors. It is airborne, but settles on eliminated, however, the number of mites can be
surfaces such as open shelving, window reduced by following prevention strategies.
ledges, curtains, blinds, upholstery, Focus initial reduction strategies in the bedroom.
carpets and can be carried in many ways,
including: human hair, animal dander, • Minimize objects that accumulate dust.
dead insect bodies, food scraps, chalk • Delegate weekly vacuuming, if
dust and talcum powder. possible or wear a mask.
• Wait 20 minutes for dust to resettle
before using the room, after vacuuming.
• Dust surfaces frequently with
a damp cloth.
Dust mites (Allergen)
Tiny microscopic creatures that feed Dust mites are found in humid, warm • Maintain relative humidity level <50%.
on the flakes of skin that people and areas. There are large concentrations (A hygrometer is a useful, inexpensive
pets shed daily. in bedrooms (pillows, blankets, carpets/ device for measuring and monitoring
rugs, mattresses, stuffed animals, indoor humidity levels.)
upholstered furniture, duvets, sheets). • Use vacuum with HEPA filter.
• Encase mattresses and pillows in
dust-mite resistant covers.
3 All About Asthma Triggers - A Practical Guide For Health Care Providers
Common Asthma Triggers
Exercise (Irritant)
Physical activity can trigger asthma Symptoms or EIA can occur with • Consider venue, time of day and weather
symptoms and may be a sign of any physical exertion, but increased conditions when planning activities.
uncontrolled asthma. Physical activity symptoms are more likely to occur • Warm-up exercise before and after
can be the only trigger for asthma during extreme temperatures (hot and physical activity. (5-10 minutes warm
symptoms and is known as Exercise humid or cold and dry) and/or when up to 60% of maximal heart rate)
Induced Asthma (EIA) or Exercise the person is recovering from a respira- • Prophylactic use of bronchodilator
Induced Bronchospasm (EIB). tory tract infection. Some people may medication 10-30 minutes prior to activity.
experience more symptoms on poor air • Elite level athletes should be referred
quality days. to a specialist for testing and advice.
4 All About Asthma Triggers - A Practical Guide For Health Care Providers
Common Asthma Triggers
Outdoor moulds are usually at their Common outdoor sources include: • Avoid walking, running or playing
peak in late summer and early fall, but decaying fallen leaves, soil, vegetation, in fallen leaves.
are present whenever there is no snow. rotting wood and grass of lawns. • Avoid raking leaves and cutting grass.
• Remove piles of raked leaves and
grass; delegate if possible.
• Avoid proximity to hay and straw.
• Avoid areas of heavy vegetation,
especially where it is not exposed
to adequate air circulation.
• Stack firewood to promote adequate
drying and air circulation.
• Stay indoors after a rainstorm,
as moulds may be stirred up.
Pollen (Allergen)
Pollens are tiny, invisible particles Pollens are found outdoors, but are • Close windows overnight to prevent
given off by trees, grass, flowers and easily wafted or carried indoors on pollens from drifting into the home.
certain weeds such as ragweed. clothing. There will be more of them • Use air conditioning to cool, dry and
where trees, grasses, flowers and/or clean the air in the home.
Pollens are at their peak at various weeds grow. • Minimize early morning outdoor
times from early spring until the first fall activity when pollen levels are
frost. It can be helpful to identify which highest (0400-1100 h).
pollen(s) is the allergen. • Close vehicle windows when travelling.
• Avoid outdoor activities on windy,
dry days when pollen and dust are
blowing around.
• Dry laundry indoors to prevent pollens
from adhering to linens and clothing.
Rodents (Allergen) The allergen is found in the feces, • Remove animal from the
dander and saliva of rodent animals environment.
(mice, rats, squirrels, gophers, • Isolate pet from bedroom and
hamsters, gerbils, guinea pigs, main living areas of the home.
chinchillas). • Limit exposure to the pet or pest.
• Wash hands with soap and water
after handling the animal.
• Seek expert service and advice to
remove animals and clean up any
areas infested by unwanted rodents.
5 All About Asthma Triggers - A Practical Guide For Health Care Providers
Common Asthma Triggers
Smoke (Irritant)
Environmental Tobacco ETS is found in any area where • Promote, encourage and support
Smoke (ETS) people smoke cigars, cigarettes, smoking cessation (Level 1).
pipes or marijuana. • Avoid second-hand smoke and
active smoking.
• Prohibit smoking in the home of
the affected person.
• Smoke outdoors, away from others.
• Prohibit smoking in vehicles.
• Avoid travelling in vehicles where
smoking is or has been permitted.
Other Smoke (Irritant) Smoke from fireplaces, grills, wood • Avoid outdoor fires, chimneys and
heaters, chimneys and campfires other open burning flames.
can be irritating. • Close windows as necessary when
smoke is in the air outdoors.
• Properly seal wood stoves.
6 All About Asthma Triggers - A Practical Guide For Health Care Providers
Common Asthma Triggers
Weather (Irritant)
Common weather triggers include: cold People may be more affected when • Warm and humidify cold air before
air, dry air, wind, humidity, extreme heat outdoors, but weather changes can breathing in through the nose.
and thunderstorms. Changes in baro- and do alter indoor environments. (Use a scarf or hand over the nose
metric pressure, wind direction and/or and mouth to create a pocket of
intensity can also trigger symptoms. warm, humid air.)
• Limit or adjust intensity level of outdoor
activity during extreme weather conditions
(cold, humid, hot, stormy or windy days).
• Use air conditioners, dehumidifiers,
fans and other appliances to maintain
comfortable indoor environments.
• Move scheduled activities indoors
or substitute with another to maintain
exercise routines when necessary.
• Schedule daily activities to take
advantage of best weather conditions.
7 All About Asthma Triggers - A Practical Guide For Health Care Providers
Asthma Triggers in Schools
8 All About Asthma Triggers - A Practical Guide For Health Care Providers
Asthma Triggers in Schools
Sulphur Oxide (SOx) Contaminants are found in emissions • Limit or reduce intensity of outdoor
is a gas formed from the sulphur from coal, oil and metal-containing activities on days with high ozone levels
contained in raw materials. ore combustion and refining processes. or other air pollutants, if necessary.
• Prohibit buses, cars and other
vehicles from idling on or adjacent
to school property.
• Avoid grass cutting during school
hours (reduce exhaust emissions
and fumes).
• Advocate for Air Quality Monitoring
and Improvement programs.
• Encourage anti-idling policies for
all vehicles and non-road engines
Nitrogen Oxides (NOx), (NO&NO2) Contaminants are found in emissions on the school property.
are compounds that include the gases from motor vehicles, diesel emissions, • Carefully consider grill and barbeque
nitric oxide and nitrogen dioxide. lawn and garden equipment, forest fires, use and location when planning events.
Produced mostly by burning fossil fuels, lightning and decaying vegetation. • Encourage children to play in areas
these are the cause of the reddish brown away from traffic and parking lots.
layer hanging over urban areas.
Note: Some patients may find it helpful to check
the following sites for information to help guide
Particulate Matter their management strategies: www.ec.gc.ca,
is a “mixture of mixtures” that consists Contaminants are found in emissions www.airqualityontario.com (May to September)
of airborne particles in solid or liquid from fuel combustion (including oil,
form. Particles smaller than 10 µm can diesel, coal, gas), electricity generation
penetrate into the lungs. (combustion turbines, industrial boilers,
power plants), wood stoves, forest fires
and fireplace soot.
Carbon Monoxide (CO)
is a gas that forms from burning fuel CO is found in emissions from
propane, natural gas, gasoline, oil, vehicles, propane barbeques, gas
coal and wood. grills and forest fires.
9 All About Asthma Triggers - A Practical Guide For Health Care Providers
Asthma Triggers in Schools
Exercise (Irritant)
Physical activity can trigger asthma Symptoms or EIA can occur with • Warm-up activity before and after
symptoms and may be a sign of any physical exertion, but increased physical activity.
uncontrolled asthma. Physical activity symptoms are more likely to occur • Prophylactic use of bronchodilator
can be the only trigger for asthma during extreme temperatures (hot and medication 10-30 minutes prior
symptoms and is known as Exercise humid or cold and dry) and/or when to activity.
Induced Asthma (EIA) or Exercise the person is recovering from a • Elite level athletes should be referred
Induced Bronchospasm (EIB). respiratory tract infection. Some people to a specialist for testing and advice.
may experience more symptoms on • Collaborate with guardian, coach/
poor air quality days. teacher to support and facilitate
optimum participation.
Pollen (Allergen)
Pollens are tiny, invisible particles given Increased pollen counts are found • Limit outdoor activities on
off by trees, grass, flowers and certain where trees, grasses, flowers and/or dry, windy days.
weeds such as ragweed. Pollens are at weeds grow and will be worse on • Schedule outdoor activities and
their peak at various times from early dry, windy days. work during the afternoon when
spring until the first fall frost. It can be counts are lower.
helpful to identify which pollen(s) is • Limit outdoor activities on days
the allergen. with high ozone levels or other
air pollutants.
10 All About Asthma Triggers - A Practical Guide For Health Care Providers
Asthma Triggers in Schools
Rodents (Allergen) The allergen is found in the feces, • Limit exposure to the animal.
dander and saliva of rodent animals • Seek expert service and advice
(mice, rats, squirrels, gophers, to remove unwanted pests and
hamsters, gerbils, guinea pigs, complete clean-up on school property.
chinchillas). • Schedule removal and clean-up
activities on weekends or holidays.
Weather (Irritant)
Common weather triggers include: cold • Warm and humidify cold air before
air, dry air, wind, humidity, extreme heat breathing in through the nose.
and thunderstorms. Changes in baro- (Use a scarf or hand over the nose
metric pressure, wind direction and/or and mouth to create a pocket of
intensity can also trigger symptoms. warm, humid air.)
• Limit or adjust intensity level of
outdoor activity during extreme
weather conditions (cold, humid,
hot, stormy or windy days).
• Limit outdoor activity during
extreme weather conditions.
• Move scheduled activities indoors
or substitute with another to maintain
exercise routines when necessary.
• Schedule daily activities to take
advantage of best weather conditions.
11 All About Asthma Triggers - A Practical Guide For Health Care Providers
Asthma Triggers in Schools
Chemicals/Agents (Irritant)
Solvents, acids, flammables, biological The chemicals/agents are found in • Conduct science experiments in
and microbiological agents, caustics, science rooms/laboratory, industrial properly designed, ventilated rooms.
and compressed gases. shops, vocational classrooms and • Use fume hoods and local exhaust
greenhouses. Activities that may systems as appropriate.
involve these are soldering, welding • Read labels and heed precautions.
and baking. Chemicals are found in • Use personal protective equipment.
machining solvents, fuels, paint and • Follow safety precautions to prevent
adhesives. air contamination through spills.
• Request Material Safety Data Sheets
from suppliers.
• Comply with WHMIS legislation.
Cockroaches (Allergen)
Common insects that can be found Allergen is found anywhere there are • Remove garbage from washrooms
anywhere in schools. They thrive where decaying cockroach body parts and and kitchen areas.
water and food are improperly stored. feces. They are found mostly in kitchens • Clean up all food crumbs or spilled
Predominant in inner city areas. and bathrooms near taps, water pipes, liquids immediately.
cupboards, appliances, toilets, garbage • Wash dishes, cooking equipment
containers and cardboard. and work tops promptly after use.
• Keep sinks, tables and floors clean
and clear of debris.
• Seal cracks and openings around
or inside cabinets.
• Store garbage in covered containers.
• Schedule any extermination
processes on weekends or holidays.
12 All About Asthma Triggers - A Practical Guide For Health Care Providers
Asthma Triggers in Schools
Dust (Irritant)
Indoor dust, unlike outdoor dust, Dust is found almost everywhere • Dust and mop with a damp cloth.
consists of a combination of materials. indoors. It is airborne, but settles on • Remove carpets.
surfaces such as open shelving, window • Reduce classroom clutter.
ledges, curtains, blinds, upholstery, • Use of HEPA filters in vacuum
carpets and can be carried in many equipment.
ways, including: human hair, animal • Use dustless chalk.
dander, dead insect bodies, food scraps,
chalk dust and talcum powder. Note: It is very difficult to avoid exposures to dust,
especially in schools. Collaboration will be required.
Exercise (Irritant)
Physical activity can trigger asthma Symptoms or EIA can be caused by • Warm-up activity before and
symptoms and may be a sign of any physical exertion, but increased after physical activity.
uncontrolled asthma. Physical activity symptoms are more likely to occur • Prophylactic use of bronchodilator
can be the only trigger for asthma during extreme temperatures (hot and medication 10-30 minutes prior to
symptoms and is known as Exercise humid or cold and dry) and/or when activity, as appropriate.
Induced Asthma (EIA) or Exercise the person is recovering from a respira- • Elite level athletes should be referred
Induced Bronchospasm (EIB). tory tract infection. Some people may to a specialist.
experience more symptoms on poor
air quality days.
13 All About Asthma Triggers - A Practical Guide For Health Care Providers
Asthma Triggers in Schools
Pollen (Allergen)
Tiny invisible particles given off Pollens are found outdoors, but are • Close windows to prevent pollens
by trees, grass, flowers and certain easily wafted or carried indoors on from wafting into the school.
weeds such as ragweed. Pollens are clothing. There will be more of them • Use air conditioning to clean,
usually at their peak in early spring where trees, grasses, flowers and/or cool and dry the air.
until the first fall frost. weeds grow.
Rodents (Allergens) The allergen is found in the feces, • Remove animal from the classroom.
dander and saliva of rodent animals • Wash hands with soap and water
(mice, rats, squirrels, gophers, ham- after handling the animal.
sters, gerbils, guinea pigs, chinchillas). • Seek expert service and advice to
remove animals and clean up any
areas infested by unwanted rodents.
• Schedule any clean-up or removal
on weekends or holidays.
14 All About Asthma Triggers - A Practical Guide For Health Care Providers
Asthma Triggers in Schools
Viral Infections (Irritant) Viruses thrive in most environments • Wash hands frequently. (Always
Rhinoviruses (common cold) and are difficult to completely avoid. after bathroom use, before food
Respiratory Syncytial Virus (RSV) They enter the body through the nose, handling, before eating and before
Parainfluenza mouth or breaks in the skin. touching nose or mouth.)
Influenza • Use alcohol-based, waterless
Adenovirus Rhinoviruses can survive on surfaces cleansers for cleaning your hands
Conovirus (telephones, railings, keyboards) when they are not visibly soiled and/
for three hours, including skin (hands). or soap and water are not available.
(Recommendation: Centre for
Disease Control)
• Arrange for children or personnel
to stay home when sick.
• Discuss vaccination with health
care provider.
• Do not share food, drink glasses
or eating utensils.
Volatile Organic VOCs are found in solvents, inks, • Substitute safer products as
Compounds (VOC) (Irritant) adhesives, glues, waxes, varnishes,
lacquers, powdered pigments, acid
often as possible.
• Store and use potentially toxic
Volatile organic compounds (VOC) clays, plaster, paper, paints, firing kilns, school supplies as directed on labels.
are carbon-containing gases and spilled liquids, paint strippers, cleaning • Remove opened containers of paint
vapours that participate in atmospheric supplies, pesticides, building materials and other products to a storage
photochemical reactions, such as (formaldehyde), furnishings, office area away from students and staff.
gasoline fumes and solvents. equipment (copiers, printers) correc- • Comply with WHMIS legislation.
tion fluids, carbonless copy paper, • Utilize integrated pest management
permanent markers and photographic techniques to reduce the need
solutions. for pesticides.
• Use the least toxic compounds
(labelled low VOC or zero VOC).
15 All About Asthma Triggers - A Practical Guide For Health Care Providers
Work-Related Asthma
Work-Related Asthma
Work-Related Asthma (WRA) is the most common chronic work-related respiratory
disease in Canada and is responsible for an estimated ten to fifteen per cent of new
onset adult asthma. Work-related asthma is defined as: asthma caused by exposure
to an agent found in the workplace according to the Canadian Thoracic Society
Guidelines. WRA can be classified into two categories:
• true “occupational asthma” which is a term reserved for asthma caused
by an exposure in the workplace.
• “work aggravated” asthma which is a term used to describe pre-existing
asthma worsened by workplace exposure.
Identifying and diagnosing WRA can be a challenging experience for health care
providers. It is important to identify if asthma symptoms are worse during working
weeks than during periods off work such as holidays. If so, then a physician
assessment is needed to start investigations for possible work-related asthma. In
this section, Work-Related Asthma, we have organized the information in a simple
format. There is no way to avoid long lists of agents that most of us cannot pro-
nounce or begin to understand, but we think you will find it easy to use this guide
by first identifying the occupation and/or industry where your patient works. From
there the lists are narrowed down to include the most common triggers in that work-
place environment. You and your patient can do some initial work to see if any of
the listed agents are known to be present in his or her workplace.
Once WRA is suspected, there are many tools and programs in the workplace
and community to assist you. Workplace Hazardous Materials Information System
(WHMIS) is a legislated program that requires labelling of containers of controlled
products and the provision of a material safety data sheet (MSDS) with each product.
Patients should be encouraged to refer to the MSDS information to assist in the
identification of potential triggers. The most important management recommendation
is to have an early and thorough medical assessment to confirm or exclude a diagnosis
of work-related asthma if this is suspected. This almost always involves a referral to
a specialist in work-related asthma. Early identification of occupational sensitizers
and the removal of sensitized patients from any further exposure are also important
aspects to the management of work-related asthma. Your patient can facilitate the
process of identification and diagnosis by providing as much information as possible.
16 All About Asthma Triggers - A Practical Guide For Health Care Providers
Work-Related Asthma
AV O I D A N C E / M A N A G E M E N T S T R AT E G I E S
In this section, general guidelines are provided to facilitate prevention or limit exposure
to an asthma-causing agent and to give guidance to control the level of exposure.
In work-related asthma, there are four strategies that apply in all situations:
• Identify asthma-causing agents in the workplace.
• Eliminate asthma-causing agents in the workplace.
• Substitute a safer agent in the workplace if the asthma-causing agent cannot be eliminated.
• Control exposure by substituting the agent with a less harmful material or utilize engineered
and hygiene measures in the workplace.
You and your patient can collaborate with personnel in the workplace to:
• Request workplace reassignment.
• Improve ventilation with installation of an exhaust ventilation system to capture emissions and vent away
from work area or enclose the industrial process.
• Use respiratory Personal Protective Devices (PPD). (Will not completely prevent WRA and requires worker
adherence as well as professional guidance to assure correct device selection and user training.)
• Use of industrial hygiene techniques as appropriate for the agent (refer to MSDS).
• Schedule regular preventative maintenance of equipment to avoid spills and other accidents.
• Seek assistance from an occupational clinic such as Occupational Health Clinics for Ontario Workers (OHCOW),
or a respiratory physician. (Check other province-specific resources.)
• Monitor ongoing exposure levels, compare industry standards and develop exposure profiles. The Industrial Accident
Prevention Association (IAPA) can assist with a monitoring process.
• Seek medical assessment and maintain medical surveillance and follow-up (pulmonary function testing, health
evaluation) for the worker.
O C C U P AT I O N / I N D U S T R Y AGENTS
Animal Breeder • Birds, cow (bovine) dander, cat, crab, deer, dog, fish-based glues, goats,
guinea pig, hamster, horses, mink, mouse, rabbit, rat, rodents, sheep
Animal Foodstuffs • Aquatic/microscopic organisms: crab allergens, arctic snow crab, lobster,
clam, shrimp meal, powdered marine sponge, cuttlefish bone dust, red soft coral,
Industry prawns, mussels, fish, fishmeal products, sea squirts
17 All About Asthma Triggers - A Practical Guide For Health Care Providers
Work-Related Asthma
O C C U P AT I O N / I N D U S T R Y AGENTS
Automotive Industry • Cobalt, vanadium, chromium, platinum, nickel, metal working fluids
• Diisocyantes: (TDI-toluene diisocyanate, HDI-hexamethylene diisocyanate, MDI-
methylene diphenyl diisocyanate, NDI-naphthalene diisocyanate, IPDI-isophorone
diisocyanate, BIC-1,3-bis cyclohexane pre-polymer)
• Amines: triethanolamine (TEA), diethanolamine (DEA), dimethylethanolamine
• Tetrachlorophthalic anhydride
• Acrylates: methyl methacrylate, cyanoacrylate, diacrylate
• Polyurethanes
• Polyvinyl chloride (PVC)
Baker/Bakeries • Flour and grains (wheat, rye, barley, rice, maize, soy, buckwheat, lupin seed, pea)
• Spices (paprika, coriander, mace-shell of nutmeg, Myristica fragrans, garlic dust,
sesame seed)
• Nuts
• Eggs, egg powder, ovalbumine, vitellus, yolk
• Lactalbumin (found in milk), milk powder
• Colour (camine red), gluten
• Lathyrus sativus (grass pea), soybean lecithin
• Yeast (Saccharomyces cerevisiae)
• Enzymes (alpha amylase, cellulose, xylanase, papain, proteases, glucose oxidase
glucoamylase, fungal amylase, hemicellulase, amyloglucosidase)
• Moulds: alternaria, aspergillus
• Insects: flour beetle, flour moth, cockroach, granary weevil
• Flour handler: konjac flour, white pea flour (Lathyrus sativus), mites, parasites
• Crustacea
Breeder • Pigeon, dove, cockatiel, parakeet, duck, turkey (feathers and droppings)
Carpenter/Woodworker • Formaldehyde
• Diisocyantes (toluene diisocyanate)
Furniture Making • Ethylene diamine (shellac/lacquer)
• Hexamethylene tetramine (lacquer)
• 3-carene dust
• Insects: Chrysonilla sitophila, grass pea (Lathyrus sativus)
• Wood: abiruana, acacia, african maple, african zebrawood, antiaris, ash,
australian blackwood, beech, box tree, brazilian walnut, cabreuva, california
redwood, cedar of lebanon, cocabolla, coniferes, ebony, gaboon/okoume, imbuia,
iroko, kotibe, mahogany, makoré, mansonia, maple, mukali, neurospora, oak,
obeche (Triplochiton scleroxylon), okoumé (marine plywood), pau, perbora,
samba, sequoia, spruce, teak, western red cedar, eastern white cedar
Cellarman • Sulphites
18 All About Asthma Triggers - A Practical Guide For Health Care Providers
Work-Related Asthma
O C C U P AT I O N / I N D U S T R Y AGENTS
Cheese Finer/Maker/ • Mites: Acarus siro (flour mites), Blonia kulagini, house dust mites
• Penicillium casei
Washer • Enzymes: pepsin, lysozyme
• Enzymes in rennet production: proteases, pepsine, chymosines
Coffee Industry • Green and roasted coffee, coffee leaves, Hemileia vastatrix (mould)
19 All About Asthma Triggers - A Practical Guide For Health Care Providers
Work-Related Asthma
O C C U P AT I O N / I N D U S T R Y AGENTS
Detergent Manufacturer • Enzymes: amylase, cellulose, Esperase, Subtilisins, lipase, Bacillus subtillis
20 All About Asthma Triggers - A Practical Guide For Health Care Providers
Work-Related Asthma
O C C U P AT I O N / I N D U S T R Y AGENTS
Fishing Industry • Aquatic/microscopic organisms: crab allergens, arctic snow crab, lobster, clam,
shrimp meal, powdered marine sponge, cuttlefish bone dust, red soft coral,
prawns, mussels, fish, fishmeal products, sea squirts (hoya), nacre (mother of pearl)
• Insects: anisakis simplex, beetles (tenebrio monitor, alphitobius, diaperinus
domestica), ech inodorus plamosus (larvae), chironomid midges, green bottle,
moths, butterflies (galleria mellonella), caddis fly, mealworm, larvae, insect
larvae (galleria mellonella), mealworm larvae (tenibrio molitor), herring
worm (anisakis simplex)
• Fish store: daphnia (water flea)(fish food store), chironimid midges
(fish food), echinodorus larva (fish food)
Food Industry • Aquatic/microscopic organisms: crab allergens, arctic snow crab, lobster, clam,
shrimp meal, powdered marine sponge, cuttlefish bone dust, red soft coral,
prawns, mussels, fish, fishmeal products, sea squirts
• Enzymes: bromelain, papain, trypsin, fungal pectinase & glucanase (food processing)
• Plants: maiko (Japanese cooking), aniseed, fenugreek
• Shark cartilage
• Pectin (christmas candy maker), carob bean (jam factory), acacia gum
• Raspberry (freeze-dried)
• Carmine (food dye)
• Artichoke, asparagus, cacao, cabbage, chicory, courgette (zucchini)
• Egg, valbumine, vitellus, yolk
• Dairy: lactoalbumin (milk protein), lactoserum
• Spices: coriander, fennel, fenugreek, nutmeg, paprika, sesame, saffron, onion seed,
garlic dust, aromatic spices
• Flour: mites and parasites
• Antibiotics: betalactoglobuline, sulfamide
• Sulphites
• Pancreatin from pig
21 All About Asthma Triggers - A Practical Guide For Health Care Providers
Work-Related Asthma
O C C U P AT I O N / I N D U S T R Y AGENTS
Groomer • Secretions from saliva, feces, urine and skin/dander of cats (most common),
dogs, horses, and other furry animals
22 All About Asthma Triggers - A Practical Guide For Health Care Providers
Work-Related Asthma
O C C U P AT I O N / I N D U S T R Y AGENTS
Mechanic • Diisocyantes
• Chlorendic anhydride
• Cobalt, vanadium, chromium, platinum, nickel
23 All About Asthma Triggers - A Practical Guide For Health Care Providers
Work-Related Asthma
O C C U P AT I O N / I N D U S T R Y AGENTS
Miller • Flour and grains (wheat, rye, barley, rice, maize, soy, buckwheat)
• Enzymes (alpha amylase, cellulose, xylanase, papain, proteases, glucose
oxidase glucoamylase, fungal amylase)
• Insects: Beetles, moths, butterflies, grain weevil, book louse, lesser
mealworm, grain mite
Mortician • Formaldehyde
Oil Industry • Castor bean, olive oil cake, flax, rapeseed oil
Pet Shop Employee • Birds, cat, crab, deer, dog, fish-based glues, guinea pig, hamster, mink,
mouse, rabbit, rat, rodents, shellfish
24 All About Asthma Triggers - A Practical Guide For Health Care Providers
Work-Related Asthma
O C C U P AT I O N / I N D U S T R Y AGENTS
25 All About Asthma Triggers - A Practical Guide For Health Care Providers
Work-Related Asthma
TRIGGER AGENTS
Potroom • Aluminum
Roofer • Chromium
Sawmill Employee • Wood: abiruana, acacia, african maple, african zebrawood, antiaris, ash,
australian blackwood, beech, box tree, brazilian walnut, cabreuva, california
redwood, cedar of lebanon, cocabolla, coniferes, ebony, gaboon/okoume,
imbuia, iroko, kotibe, mahogany, makoré, mansonia, maple, mukali, neurospora,
oak, obeche, okoumé (marine plywood), pau, perbora, samba, sequoia, spruce,
teak, western red cedar, eastern white cedar
• Mould: Trichoderma koningii
26 All About Asthma Triggers - A Practical Guide For Health Care Providers
Work-Related Asthma
TRIGGER AGENTS
Tinsmith • Diisocyantes
Veterinarian/ • Antibiotics: tylosin (used in animal health and growth agent), spiramycine,
erythromycine, oleandomycine
Veterinarian Assistant • Piperazine
• Birds, cow (bovine) dander, cat, crab, deer, dog, fish-based glues, goats, guinea
pig, hamster, horses, mink, monkey, mouse, rabbit, rat, rodents, sheep, shellfish
27 All About Asthma Triggers - A Practical Guide For Health Care Providers
Agricultural Asthma Triggers
28 All About Asthma Triggers - A Practical Guide For Health Care Providers
Agricultural Asthma Triggers
General
Includes the most common triggers Mites: There are four basic strategies that
generally found in most farm Barn mite (Acarus siro, Acarus should be applied in an agricultural/
environments, with the potential farris, Blomia Kulagini, Euroglyphus) farm environment:
to affect any of the workers and/or Two spotted spider mite
visitors to the site. (Tetranychus urticae) • Identify asthma-causing agents.
• Eliminate asthma-causing agents.
Mould Spores • Substitute a safer agent if the
asthma-causing agent cannot be
Feed enhancer: eliminated.
Phystase • Control exposure by substituting
Betaglucanase the agent with a less harmful material
Amprolium hydrochloride or utilize engineered and hygiene
measures.
Common antibiotics in feeds:
Tetracyclines, sulphas, neomycin, Note: Respirators offer the single greatest
bacitracin, lincomycin, apramytin, tylo- protection against work-related asthma, but
sin, lasalocid, spiramycin, amprolium. cannot provide complete protection.
Phosphate Fertilizers:
Normal superphosphate (0-20-O)
Concentrated superphosphate (0-45-O)
29 All About Asthma Triggers - A Practical Guide For Health Care Providers
Agricultural Asthma Triggers
Nitrogen/Phosphate Fertilizers:
Monoammonium phosphate (11-52-O)
Ammonium phosphate sulfate
(16-20-O-153)
Potassium Fertilizers:
Potassium chloride
Potassium sulfate
Potassium nitrate
Anhydrous ammonia
(injected into soil)
Insecticides
(chemicals used to control insects)
Organophosphate
Miticides/Acaricides
(chemicals used to control mites)
Fungicides
(chemicals used to control moulds)
Chlorothalonil
Herbicides
(chemicals used to control
unwanted plants)
Rodenticides
(chemicals used to control rodents)
Nematicides
(chemicals used to control nematodes)
Disinfectants: Chloramine-T,
ammonium, aldehydes.
30 All About Asthma Triggers - A Practical Guide For Health Care Providers
Agricultural Asthma Triggers
Livestock
Cattle/Dairy/Other Endotoxin is present from • Increase ventilation in
contaminating bacteria of: confinement buildings.
Cow dander • Reduce number of animals
Cow urine per unit area.
Sheep epithelium • Increase frequency of manure
Goat epithelium removal.
Horse hair • Install ammonia level sensors.
Rabbit hair • Use respirators that remove ammonia.
Rabbit epithelium • Use ventilated hoods or safety
Mink urine cabinets during animal manipulations.
Deer dander • Avoid wearing street clothes.
Dairy cattle/milk production • Store work clothes at the workplace
Beef cattle/ranching, Sheep, Goat and wash separately in hot water.
Horse, Rabbit, Other livestock, • Keep cages and animal areas clean.
Honey Bees. • Wear gloves, aprons, coveralls.
• Install ventilated animal cage
racks or filter-top cages.
• Replace sawdust bedding with
absorbent pads or corncob bedding.
31 All About Asthma Triggers - A Practical Guide For Health Care Providers
Agricultural Asthma Triggers
Fruit and Vegetable Fruit Mites: Note: Respirators offer the single greatest protection
Fruit tree red spider mite (Tetranychus against work-related asthma, but cannot provide
urticae), Acarian-mite or tick complete protection.
(Panonychus ulmi), Citrus red mite
(Panonychus citri). • Use Personal Protection Equipment
(PPE) when spraying, harvesting,
Fruit Mould: weeding, tilling or working in animal
Downy Mildew (Plasmopara Viticol). confinement buildings.
Vine grower:
Acarian - McDaniel spider mite
(Tetranychus macdanieli),
Pollen (Diplotaxis erucoides).
Granary Worker
Soybean, Oilseed (except soybean) Grain dust: • Use oil misting systems.
Dry pea and bean, Wheat, Corn, Consists of different types of grain, • Use PPE when grain handling.
Other grain insect parts, mould, bacteria, bird • Ensure adequate drying and
and rodent droppings, pesticides conditioning prior to storage.
and silica. Includes: wheat, rye, barley, • Store grain at recommended moisture
rice, maize, soy, buckwheat. content levels to limit mould growth.
• Utilize anti-mould sprays or
Storage mites: preparations to reduce mould.
Tyrophagus longior, T. putrescentiae, • Spray water or canola oil on feed
Glycyphagus destructor, G. domesticus, or bedding prior to distribution
Acarus siro, A. farris, Dermatophagoides in enclosed spaces and automatic
pteronyssinus, D. farinae, Ornithonys- feeding systems.
sus sylviarum. • Install exhaust fans in all storage
areas. Use covers or screen equip-
Beetles: ment during transfer of grain.
Tenebrio monitor, Alphitobius, • Extend exhaust pipes to higher,
Hay Diaperinus domestica, grain weevil. faster moving air (above head height).
All other miscellaneous crops
Other food crops grown under cover Insects:
grain mite, grain pests, Eurygaster
and Ephestia, Lesser mealworm,
Oilseed rape (canola).
32 All About Asthma Triggers - A Practical Guide For Health Care Providers
Agricultural Asthma Triggers
Chemicals:
Includes: fertilizers, pesticides,
herbicides, insecticides.
Mushroom Mould spores Note: Respirators offer the single greatest protection
White Mushroom (Agaricus bisporus) against work-related asthma, but cannot provide
complete protection.
Mites and other insects (predatory,
pests and pollinators) • Use Personal Protection Equipment
(PPE) when spraying, harvesting,
Pollen and plant oils weeding, tilling or working in animal
confinement buildings.
Chemicals including: fertilizers,
pesticides, herbicides and insecticides.
33 All About Asthma Triggers - A Practical Guide For Health Care Providers
Special Considerations
Special Considerations
Ideally, by the time you get to this last section of the guide, you and your patient
have been able to identify the triggers that are potentially exacerbating his or her
asthma symptoms. In this section, Special Considerations, we have included some
extra information for you to think about. Although limited, this information is
intended to remind you that further assessment of any potential contributing fac-
tors may be necessary. Again, sometimes the evidence is not compelling and can be
controversial; however, it is up to us, as health care providers to make good use of
both the scientific data available, as well as the collective wisdom and experience
of good practice. We encourage you to seek more information and/or expert advice
about any of these special considerations that may be pertinent to your patient.
34 All About Asthma Triggers - A Practical Guide For Health Care Providers
Special Considerations
Food
Food allergy is a very uncommon cause The most common foods causing Note: Although caution and good judgement are
of asthma. Typically, food allergy that serious allergic reactions include: essential, proper allergy skin testing and assessment
causes asthma symptoms occurs with eggs, fish, milk, peanuts, shellfish, soy, are required to confirm a suspected food allergy.
episodes of anaphylaxis. Therefore tree nuts (walnuts, cashews), wheat Thorough assessment by an allergist is highly
other symptoms such as throat tightness, and sesame seeds. recommended.
pruritis, urticaria and/or even symptoms
of low blood pressure occur when food • Eliminate the identified food(s)
allergy is a cause of asthma. A proper from the diet.
assessment and allergy testing must be • Read food labels carefully.
performed to confirm the existence of • Inform those involved in meal
a food allergy. If food allergies and planning/food preparation (family,
asthma coexist, the person is at more caregivers, schools, restaurants).
risk of life threatening events. • Ask about ingredients always.
• Educate children as soon as possible
(ask, identify and self-advocate).
• Wear a Medic Alert® bracelet.
• Discuss/seek expert advice about the
Food Additives need for Epipen® or Twinject®.
While many food additives such as Sulphites are commonly found in:
dyes and preservatives have long been dried fruits, wine, bottled lime or lemon Note: Anaphylaxis Canada is a valuable
suspected of causing increased symp- juice, prepared potatoes and shrimp. resource for health care providers and patients;
toms, only sulphites have been proven www.anaphylaxis.org
to do so.
Emotions
Psychological factors, especially stress, • Initiate discussion about the impact
can trigger or exacerbate asthma of emotions on health in general and
symptoms. Studies have shown that more specifically breathing.
psychological factors can lead to • Practise relaxation techniques.
increased airway inflammation. • Review and adjust management strat-
egies (Action Plan), as appropriate.
Hormones
Some women notice that their asthma • Discuss adjustment to medication
symptoms are worse just before men- routine (Action Plan).
struation begins or during ovulation.
35 All About Asthma Triggers - A Practical Guide For Health Care Providers
Special Considerations
Pregnancy
Asthma control during pregnancy may • Discuss plans for pregnancy with
remain unchanged, improve or become physician in advance, when possible.
worse. Generally, control will return • Seek advice and guidance from physi-
to the pre-pregnancy level three months cian once pregnancy is confirmed.
postpartum. Well-controlled asthma • Avoid irritants and allergens as
increases maternal comfort and much as possible to decrease
improves safety and outcomes for need for medication.
both mother and baby. • Discuss choice, risks and benefits
of medications.
Rhinitis, Sinusitis
Research suggests that inflammation Discuss signs and symptoms of • Treat rhinitis and sinusitis.
of the upper airway from rhinitis and rhinitis and sinusitis with every patient • Discuss management of rhinitis
sinusitis results in increased bron- who has asthma. and sinusitis with physician.
choconstriction of the lower airways. • Manage allergic triggers as described
Increasing evidence is suggesting the in other sections.
concept of one airway, one disease.
Up to 80% of patients with asthma have
rhinitis and about 15% of patients with
allergic rhinitis have asthma. Rhinitis
and sinusitis are associated with more
severe asthma symptoms and increased
exacerbations in patients with poorly
controlled asthma. Rhinitis and
sinusitis must be treated.
Aspirin (ASA)
Non-Steroidal Anti-Inflammatory Taking a careful history can help • Avoid ASA and NSAIDs as well as
Drugs (NSAIDs) to identify this. any medications containing these.
ASA/NSAIDs can induce increased • Notify pharmacist and physician
asthma symptoms in about 28% of for inclusion on records.
adults, but rarely affect children.
Beta Blockers
Beta Blockers are medications commonly Check with pharmacist or other • Discuss potential alternative medica-
used to manage hypertension, cardiac source to accurately identify these tion choices with physician.
disease, eye disease and headaches. medications.
They will interfere with Beta-agonists
(bronchodilators) and patients with
asthma will not benefit optimally from
their reliever medication.
36 All About Asthma Triggers - A Practical Guide For Health Care Providers
Special Considerations
Gastroesophogeal
Reflux (GERD)
The relationship between GERD and As many as 89% of patients with • Avoid fatty foods, caffeine, chocolate,
asthma is controversial although many asthma may have GERD and many peppermint, citrus juices, tomato
studies have shown an interaction of those patients may have “silent” products and alcohol.
between the two diseases. Studies have reflux, with no symptoms. Therefore • Avoid large meals.
shown that if you have asthma you have it is important to discuss signs and • Avoid eating before going to bed.
a higher chance of having GERD. symptoms of GERD with patients. • Elevate head of bed.
• Stop smoking.
• Consider medication.
Obesity
Asthma is thought to be more prevalent • Discuss weight management strategies.
in obese people. Obesity is also thought • Increase exercise, as appropriate.
to make asthma more difficult to control • Refer to Canada’s Food Guide:
and causes increased symptoms. The www.hc-sc.gc.ca
exact mechanism is not understood.
37 All About Asthma Triggers - A Practical Guide For Health Care Providers
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40 All About Asthma Triggers - A Practical Guide For Health Care Providers
Common Asthma Triggers
Dust mites Dust mites are also found everywhere, • Wash all bedding in hot water
Tiny microscopic creatures that feed on but in large concentrations in bed- (130-140°F) weekly.
the flakes of skin that people and pets rooms. Cotton fibres (pillows, blankets, • Freeze non-washable items
shed daily. They thrive in warm and carpet, mattresses, stuffed animals, (quilts, stuffed animals) in freezer (or
humid environments. upholstered furniture) leave outside overnight in freezing
temperatures).
• Remove stuffed animals from bedroom.
• Replace (if possible) carpets, rugs, heavy
draperies and upholstered furniture.
Exercise
Physical Activity can be the only trigger Any physical exertion. Note: A favourite stuffed animal can be washed
for asthma symptoms. And is known as and placed in the drier, followed by an overnight stay
Exercise Induced Asthma (EIA). in the freezer. This will reduce the mites, while keep-
ing a little one happy!
Physical activity can trigger asthma
symptoms and may be a sign of • Prophylactic use of bronchodilator
uncontrolled asthma. medication 20-30 minutes prior
to activity. (Level 1)
• Warm up before and after
physical activity.
• Consider venue, time of day
and weather conditions when
planning activities.
• Elite level athletes should be
referred to a Specialist for testing
and advice.
Mould Spores
Tiny structures produced by moulds Spores are airborne and are found Note: There is no practical way to eliminate all moulds
for reproduction purposes. in places where mould grows. indoors. The best way to control indoor mould growth
is to control moisture. Prevention is key.
Common spores: Common indoor areas include:
Alternaria showers, bathrooms, window sills, • Maintain relative humidity level
Aspergillus laundry rooms, kitchens, refrigerators, <50%.(A hygrometer is a useful and
Bipolaris garbage containers, carpets, upholstery, inexpensive device for measuring and
Cladosporium attics, basements monitoring indoor humidity levels.)
Epicoccum • Promote air circulation with open
Fusarium windows and use of vents and fans.
Acknowledgements
Penicillium • Clean showers/bathtubs after each
Common spores: use to prevent mildew.
Alternaria
The Primary Care Asthma Co-ordinators’ Group
Aspergillus
The Ontario Lung Association • Maintain relative humidity level
Bipolaris
The Lung Association is also grateful to the Government of Ontario for <50%.(A hygrometer is a useful and
Cladosporium
funding that supported the development, printing and distribution of this publication. inexpensive device for measuring and
Epicoccum monitoring indoor humidity levels.)
Fusarium • Promote air circulation with open
Penicillium Common spores: windows and use of vents and fans.
Alternaria • Clean showers/bathtubs after each
Aspergillus
Ontario’s useoftothirteen
Asthma Plan of Action is a long-term strategy based on the current Canadian asthma guidelines and is comprised prevent mildew. initiatives that
cross-ministerial
Bipolaris
include • Maintain
health promotion and prevention, management and treatment, research and surveillance. For children and adults relative
with asthma, humidity
the goals of the Planlevel
are to reduce
mortality, morbidity and health care costs through an integrated approach with the Ministry of Health and Long-Term Care coordinating and overseeing the efforts.
573 King Street East
Toronto, Ontario, Canada M5A 4L3
www.on.lung.ca
To order copies of this publication, call The Lung Association’s Asthma Action Helpline at
1-888-344-LUNG (5864). It is also available at: www.on.lung.ca