MALIGNANT HYPERTHERMIA, RHABDOMYOLYSIS, PROPOFOL INFUSION SYNDROME QUIZ

Name: Date:

Level:

MALIGNANT HYPERTHERMIA
1. Which of the following is a Non-Specific clinical feature of Malignant Hyperthermia
A. Increase in end-tidal CO2 during constant ventilation
B. Generalized rigidity
C. Masseter muscle rigidity
D. Increased temperature, which may exceed 40⁰C

2. A safe drug to use in Malignant Hyperthermia

A. Halothane B. Sevoflurane C. Propofol D. Succinylcholine

3. The initial intravenous dose of dantrolene

A. 1.5 mg/kg B. 2.0 mg/kg C. 2.5 mg/kg D. 3.0 mg/kg

4. NOT recommended in the management of a MH susceptible patient

A. Preparation of the anesthesia machine includes removal or closure of vaporizers, change of all disposable
components, and flushing the machine with 100% oxygen (may require >2 hours).

B. Charcoal filters attached to both limbs of the anesthesia breathing circuit before and during the procedure
are effective for reducing halogenated anesthetics to less than trace amounts.

C. Preoperative administration of prophylactic dantrolene

D. Preparing routine American Society of Anesthesiologists (ASA) monitors including: Pulse oximeter,
Capnometer, Core temperature monitor, ECG and blood pressure monitors

RHABDOMYOLYSIS
1. Triad of Rhabdomyolysis are the ff except:
A. Myalgia B. Palpitations C. Tea colored urine D. Muscle weakness

2. Hallmark of acute rhabdomyolysis is increase in:

A. creatine phosphokinase (CPK) B. liver function tests C. CK-MB D. ESR

3. Rhabdomyolysis is associated with:

A. Hypocalcemia B. Hyperkalemia C. Hyperphosphatemia D. All of the above

PROPOFOL INFUSION SYNDROME

1. Clinical features of propofol infusion syndrome EXCEPT
A. Metabolic acidosis B. Hypokalemia C. Rhabdomyolysis D. Acute bradycardia leading to asystole

2. Management of propofol infusion syndrome EXCEPT

A. prompt recognition and discontinuation of propofol
B. initiate alternative sedation agent
C. discontinue inotropes or vasopressors
D. hemodialysis

3. TRUE OR FALSE: Risk factor for propofol infusion syndrome includes infusion rate exceeding 83 mcg/kg/minute
for 24hours