Petra

University Faculty of Pharmacy and Medical Sciences Department of Pharmaceutics and Pharmaceutical Technology
Coure Title: Course No: Level: Credit Hours: Prerequisite: Pharmaceutical Dosage Forms and Compounding 501346 Thired year 3 credit hours Physical Pharmacy 2 (501345)

Instructor: Dr. Majid Feddah Phone 5715891, ext 518 Suggested References: Pharmaceutical Dosage Forms and Drug Delivery Systems Howard C. Ansel, Nicholas G. Popovich, Loyd V. Allen, Jr. 2- Martin's, Physical Pharmacy and Pharmaceutical Sciences. 3- Pharmaceutical Practice, A.J.Winfield, R.M.E. Richards Students are also responsible for all material covered in lectures. Course Description (Aim and Objectives): This course is designed to introduce pharmacy students to the phamaceutic principles and techologies applied in the preparation of : Solutions, Suspensions, Emulsions, and Semi-Solid dosage forms (Ointments, Creams, Pastes, Gels, and suppositories). Teaching Methods: 1. Lectures. 3. Engaging students in active learning by probing discussions during lecture. 2. Homework assignments. Course duration: Duration 6 hours/weeks for 16 weeks Course Outline: Solutions Solubility Solvent for liquid preparations Preparation of solutions Oral solutions and preparations of oral solution Dry mixtures for oral solution Oral solutions Oral rehydration solutions Oral colonic lavages solution Magnisum citrate oral solution Sodium citrate and citric acid oral solution

Syrups Antimicrobial preservatives Flavorant Colorant Elixirs Preparation of Elixirs Types of Elixirs Tinctures Vaginal and rectal solutions Nasal preparations Inhalent Otic solutions Spirits Collodions Extraction methods for prparing solutions Chapter II Suspensions Reasons for suspensions Features desired in pharmaceutical suspension Sedimentation rate of the particles of a suspension Preparation of suspensions Sustained-release suspensions Packaging and storage of suspensions Examples of oral suspensions Chapter III Emulsions Purpose os emulsions and of emulsification Theories of emulsification Preparation of emulsion The HLB system Microemulsions Stability of emulsions Examples of oral emulsion Chapter IV Semisolids preparations Ointments, Creams and Gles Ointments Ointment bases Hydrocarbon bases Preparations of ointments Compendial requirements for ointments Gels Features and use of Dermatologic preparations Features and use of ophthalmic ointments and gels. Features and use of Nasal ointments and gels. Features and use of rectal preparations.

Exams and Grading System: First Exam Second Exam Lab. Final Exam (All Material)

Percent of Total Grade 12.5 % 12.5 % 25 % 50 %

Attendance Policy: Lecture attendance is mandatory. The student is maximally allowed a 15% absentia of total class hours. Each student will get two formal notices of his/her absentia. The student with an excuse will be drawn from the course. Otherwise, s/he will be deprived from the course with a zero mark assigned.