Mustard Database

Mustard is a database that tracks Antimicrobial Resistance

Determinants (ARDs). The method by which it tracks ARDs is
Mustard
using their own method adapted from Protein Homology Content
Modelling called Pairwise Comparative Modelling (PCM), which Description Contains AR
increase specificity protein prediction, especially for distantly
determinants and
related protein homologues.[1] Using PCM, 6095 ARDs from 20
curated AR
families in the human gut microbiota. Antibiotic resistance
genes identified
databases used were ResFinder,[2] ARG-ANNOT,[3] the now
from
defunct Lahey Clinic,[4] Marilyn Roberts website for tetracycline
metagenomics
and macrolide resistance genes[5] and metagenomics.[6][7][8]
Data types Antimicrobial
captured resistance genes
See also
and AR
Antimicrobial Resistance databases Determinants
Organisms Bacteria
References Contact
Primary citation PMID 30478291
1. Ehrlich, S. Dusko; Kennedy, Sean P.; Doré, Joël;
(https://pubmed.
Haimet, Florence; Weiszer, Kevin; Levenez, Florence;
Letur, Aline; Léjard, Véronique; Léonard, Pierre ncbi.nlm.nih.gov/
(January 2019). "Prediction of the intestinal resistome 30478291)
by a three-dimensional structure-based method" (http://p Access
ure-oai.bham.ac.uk/ws/files/56105905/Ruppe_et_al_Pr
ediction_of_the_intestinal_resistome_Nature_Microbiol Website mgps.eu/Mustard
ogy_2018.pdf) (PDF). Nature Microbiology. 4 (1): 112– / (http://mgps.eu/
123. doi:10.1038/s41564-018-0292-6 (https://doi.org/10. Mustard/)
1038%2Fs41564-018-0292-6). ISSN 2058-5276 (https:// Download URL Download (http://
www.worldcat.org/issn/2058-5276). PMID 30478291 (htt
mgps.eu/Mustar
ps://pubmed.ncbi.nlm.nih.gov/30478291).
d/index.php?id=d
S2CID 53757858 (https://api.semanticscholar.org/Corpu
sID:53757858). b)

2. Zankari, E.; Hasman, H.; Cosentino, S.; Vestergaard, M.; Miscellaneous

Rasmussen, S.; Lund, O.; Aarestrup, F. M.; Larsen, M. V. Bookmarkable yes
(2012-07-10). "Identification of acquired antimicrobial entities
resistance genes" (https://www.ncbi.nlm.nih.gov/pmc/arti
cles/PMC3468078). Journal of Antimicrobial
Chemotherapy. 67 (11): 2640–2644. doi:10.1093/jac/dks261 (https://doi.org/10.1093%2Fja
c%2Fdks261). ISSN 0305-7453 (https://www.worldcat.org/issn/0305-7453). PMC 3468078
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3468078). PMID 22782487 (https://pubmed.
ncbi.nlm.nih.gov/22782487).
3. Gupta, Sushim Kumar; Padmanabhan, Babu Roshan; Diene, Seydina M.; Lopez-Rojas,
Rafael; Kempf, Marie; Landraud, Luce; Rolain, Jean-Marc (2013-10-21). "ARG-ANNOT, a
New Bioinformatic Tool To Discover Antibiotic Resistance Genes in Bacterial Genomes" (htt
ps://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910750). Antimicrobial Agents and
Chemotherapy. 58 (1): 212–220. doi:10.1128/aac.01310-13 (https://doi.org/10.1128%2Faac.
 01310-13). ISSN 0066-4804 (https://www.worldcat.org/issn/0066-4804). PMC 3910750 (http
s://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910750). PMID 24145532 (https://pubmed.ncbi.
nlm.nih.gov/24145532).
4. "RED-DB" (http://www.fibim.unisi.it/REDDB/). Retrieved July 27, 2019.
5. "Marilyn Roberts website" (http://faculty.washington.edu/marilynr/).
6. Allen, Heather K; Moe, Luke A; Rodbumrer, Jitsupang; Gaarder, Andra; Handelsman, Jo
(2008-10-09). "Functional metagenomics reveals diverse β-lactamases in a remote Alaskan
soil" (https://doi.org/10.1038%2Fismej.2008.86). The ISME Journal. 3 (2): 243–251.
doi:10.1038/ismej.2008.86 (https://doi.org/10.1038%2Fismej.2008.86). ISSN 1751-7362 (htt
ps://www.worldcat.org/issn/1751-7362). PMID 18843302 (https://pubmed.ncbi.nlm.nih.gov/1
8843302). S2CID 16496336 (https://api.semanticscholar.org/CorpusID:16496336).
7. Moore, Aimée M.; Patel, Sanket; Forsberg, Kevin J.; Wang, Bin; Bentley, Gayle; Razia,
Yasmin; Qin, Xuan; Tarr, Phillip I.; Dantas, Gautam (2013-11-13). "Pediatric Fecal Microbiota
Harbor Diverse and Novel Antibiotic Resistance Genes" (https://doi.org/10.1371%2Fjournal.
pone.0078822). PLOS ONE. 8 (11): e78822. doi:10.1371/journal.pone.0078822 (https://doi.o
rg/10.1371%2Fjournal.pone.0078822). ISSN 1932-6203 (https://www.worldcat.org/issn/1932
-6203). PMID 24236055 (https://pubmed.ncbi.nlm.nih.gov/24236055).
8. Sommer, M. O. A.; Dantas, G.; Church, G. M. (2009-08-27). "Functional Characterization of
the Antibiotic Resistance Reservoir in the Human Microflora" (https://www.ncbi.nlm.nih.gov/p
mc/articles/PMC4720503). Science. 325 (5944): 1128–1131. doi:10.1126/science.1176950
(https://doi.org/10.1126%2Fscience.1176950). ISSN 0036-8075 (https://www.worldcat.org/is
sn/0036-8075). PMC 4720503 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720503).
PMID 19713526 (https://pubmed.ncbi.nlm.nih.gov/19713526).

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