FARME

FARME also known as Functional Antibiotic Resistance

Metagenomic Element is a database that compiles publicly
Functional Antibiotic
available DNA elements and predicted proteins that confer Resistance Metagenomic
antibiotic resistance, regulatory elements and mobile genetic Element
elements. It is the first database to focus on functional Content
metagenomics. This allows the database to understand 99% of
Description Compilation of
bacteria which cannot be cultured, the relationship between
environmental antibiotic resistance sequences and antibiotic genes publicly available
derived from cultured isolates.[1] This information was derived predicted
from 20 metagenomics[2][3][4] projects from GenBank. Also from proteins and
GenBank are the protein sequence predictions and annotations. DNA elements
that confer
Antibiotic
See also
Resistance,
Antimicrobial Resistance databases regulatory
elements and
mobile genetic
References elements.
1. Wallace, James C.; Port, Jesse A.; Smith, Marissa N.; Data types Antimicrobial
Faustman, Elaine M. (2017). "FARME DB: a functional captured resistance genes
antibiotic resistance element database" (https://www.nc and DNA
bi.nlm.nih.gov/pmc/articles/PMC5225399). Database. Elements
2017: baw165. doi:10.1093/database/baw165 (https://do
i.org/10.1093%2Fdatabase%2Fbaw165). ISSN 1758- Organisms Bacteria
0463 (https://www.worldcat.org/issn/1758-0463). Contact
PMC 5225399 (https://www.ncbi.nlm.nih.gov/pmc/article
s/PMC5225399). PMID 28077567 (https://pubmed.ncbi. Primary citation PMID 28077567
nlm.nih.gov/28077567). (https://pubmed.
2. Forsberg, K. J.; Reyes, A.; Wang, B.; Selleck, E. M.; ncbi.nlm.nih.gov/
Sommer, M. O. A.; Dantas, G. (2012-08-30). "The 28077567)
Shared Antibiotic Resistome of Soil Bacteria and Access
Human Pathogens" (https://www.ncbi.nlm.nih.gov/pmc/a
Website staff.washington
rticles/PMC4070369). Science. 337 (6098): 1107–1111.
Bibcode:2012Sci...337.1107F (https://ui.adsabs.harvard. .edu/jwallace
edu/abs/2012Sci...337.1107F). /farme/ (http://sta
doi:10.1126/science.1220761 (https://doi.org/10.1126% ff.washington.ed
2Fscience.1220761). ISSN 0036-8075 (https://www.worl u/jwallace/farm
dcat.org/issn/0036-8075). PMC 4070369 (https://www.n e/)
cbi.nlm.nih.gov/pmc/articles/PMC4070369).
PMID 22936781 (https://pubmed.ncbi.nlm.nih.gov/2293 Download URL Download (http://
6781). staff.washington.
3. Moore, Aimée M.; Patel, Sanket; Forsberg, Kevin J.; edu/jwallace/farm
Wang, Bin; Bentley, Gayle; Razia, Yasmin; Qin, Xuan; e/download.html)
Tarr, Phillip I.; Dantas, Gautam (2013-11-13). "Pediatric Miscellaneous
Fecal Microbiota Harbor Diverse and Novel Antibiotic
 Resistance Genes" (https://www.ncbi.nlm.nih.gov/pmc/a Bookmarkable yes
rticles/PMC3827270). PLOS ONE. 8 (11): e78822. entities
Bibcode:2013PLoSO...878822M (https://ui.adsabs.harv
ard.edu/abs/2013PLoSO...878822M). doi:10.1371/journal.pone.0078822 (https://doi.org/10.1
371%2Fjournal.pone.0078822). ISSN 1932-6203 (https://www.worldcat.org/issn/1932-620
3). PMC 3827270 (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3827270).
PMID 24236055 (https://pubmed.ncbi.nlm.nih.gov/24236055).
4. Parsley, L. C.; Consuegra, E. J.; Kakirde, K. S.; Land, A. M.; Harper, W. F.; Liles, M. R. (2010-
04-09). "Identification of Diverse Antimicrobial Resistance Determinants Carried on
Bacterial, Plasmid, or Viral Metagenomes from an Activated Sludge Microbial Assemblage"
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876469). Applied and Environmental
Microbiology. 76 (11): 3753–3757. Bibcode:2010ApEnM..76.3753P (https://ui.adsabs.harvar
d.edu/abs/2010ApEnM..76.3753P). doi:10.1128/aem.03080-09 (https://doi.org/10.1128%2F
aem.03080-09). ISSN 0099-2240 (https://www.worldcat.org/issn/0099-2240). PMC 2876469
(https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2876469). PMID 20382816 (https://pubmed.
ncbi.nlm.nih.gov/20382816).

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