ARDB

ARDB also known as Antibiotic Resistance Genes Database is

a database that tracks antibiotic resistance genes with information
Antibiotic Resistance
such as mechanism of action, resistance profile, ontology, Clusters Genes Database
of Orthologous Genes (COG) and Conserved Domain Database Content
(CDD) annotations.[1] It also contains links to external databases. Description A database that
The database is also for the identification of new resistance genes.
tracks antibiotic
During the creation of ARDB in 2009, there was no
resistance
comprehensive annotation system available. Thus, ontology terms
for resistance profiles and mechanisms of actions were created for genes.
ARDB. Other things classified by ontology include drug target Data types Antibiotic
modification, drug enzymatic destruction and drug transport.[1] captured resistance genes
Drug transporters are further subclassified by MFS Efflux pumps,
Organisms Bacteria
SMR Efflux pumps, ABC Efflux pumps, RND Efflux pumps
following conventions outlined in this paper.[2] Currently, ARDB Contact
contains resistance information for 13,293 genes, 377 types, 257 Primary citation PMID 18832362
antibiotics, 632 genomes, 933 species and 124 genera. (https://pubmed.
ncbi.nlm.nih.gov/
ARDB is no longer maintained. All ARDB data are in CARD,
18832362)
which the developers now recommend instead.
Access

See also Website ardb.cbcb.umd

.edu (http://ardb.
Antimicrobial Resistance databases cbcb.umd.edu)
Miscellaneous
References Bookmarkable yes
entities
1. Liu, B.; Pop, M. (2009-01-01). "ARDB--Antibiotic
Resistance Genes Database" (https://www.ncbi.nlm.nih.
gov/pmc/articles/PMC2686595). Nucleic Acids Research. 37 (Database): D443–D447.
doi:10.1093/nar/gkn656 (https://doi.org/10.1093%2Fnar%2Fgkn656). ISSN 0305-1048 (http
s://www.worldcat.org/issn/0305-1048). PMC 2686595 (https://www.ncbi.nlm.nih.gov/pmc/arti
cles/PMC2686595). PMID 18832362 (https://pubmed.ncbi.nlm.nih.gov/18832362).
2. Higgins, Christopher F. (April 2007). "Multiple molecular mechanisms for multidrug
resistance transporters". Nature. 446 (7137): 749–757. Bibcode:2007Natur.446..749H (http
s://ui.adsabs.harvard.edu/abs/2007Natur.446..749H). doi:10.1038/nature05630 (https://doi.or
g/10.1038%2Fnature05630). ISSN 0028-0836 (https://www.worldcat.org/issn/0028-0836).
PMID 17429392 (https://pubmed.ncbi.nlm.nih.gov/17429392). S2CID 4414214 (https://api.se
manticscholar.org/CorpusID:4414214).

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