Researchh Ppaer REal Not FAek 1

BACOOR NATIONAL HIGH SCHOOL MAIN
MOLINO I, CITY OF BACOOR, CAVITE
TBantay: DEVELOPMENT OF A TUBERCOLOSIS

PATIENT MONITORING APPLICATION
USING MACHINE LEARNING
A RESEARCH PROJECT PROPOSAL
Deado, Claire Eugene L.

Angeles, Andrea Kate G.
Baldago, Adam T.
Ramos, James Lemuel C.
Berbon, Rafael Athrun DP.
Jarabelo, Keziah Ashley I.
Special Science Curriculum

Science and Technology Engineering (SSC-STE)
Research III
Mr. Richard L. Nocillado

Research Adviser
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Group 4 – “TBantay: Development of a Tuberculosis Patient Monitoring Application
Using Machine Learning”
June 2023
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TABLE OF CONTENTS
Acknowledgement
Abstract
Chapter Page
I. INTRODUCTION 5
Background of the Study 5
Significance of the Study 6
Statement of the Problem 7
Research Hypotheses 8
Conceptual Framework 9
Scope and Limitations 10
Definition of Terms 10
II. REVIEW OF RELATED LITERATURE 12
Conceptual Literature 12
Foreign Studies 13
Local Studies 16
Synthesis 18
Justification of the Study 19
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III. METHODOLOGY 2
Research Design 22
Materials and Procedures 23
Experimental Design 25
Experimental Flowchart 26
Statistical Treatment 27
References 28
Appendices 31
Appendix A Budget Plan 32
Appendix B Project Data Book 33
Appendix C Project Approval Form 34
Appendix D Curriculum Vitae 35
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ACKNOWLEDGEMENTS
We would like to acknowledge and thank the people who have provided us the
guidance and support we needed throughout the creation and development of this
research paper.
To our research adviser, Mr. Richard L. Nocillado, for his hard work and effort in
checking, proofreading, and helping us create a proper and well-written research paper.
Thank you for your patience and guidance.
To our robotics coach, Mr. Rod Edmon Torreliza, for helping us conceptualize and
guiding us as we explore the field of computational science. Thank you for your advice
and support.
To our parents and guardians for their never-ending support. Thank you for
assisting and helping us.
Lastly, we would like to extend our gratitude to our Father God, for guiding and
protecting us, giving us enough strength and energy to overcome hardships we
encountered during the creation of our research paper, leading to its completion.
The Researchers
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Chapter I
INTRODUCTION
1.1 Background of the Study
Tuberculosis (TB) is a serious, potentially life-threatening infectious disease
caused by a bacteria called Mycobacterium tuberculosis. It is a disease that primarily
affects the lungs, though it can also affect other organs such as the brain, spine, and
kidneys (Cleveland Clinic, 2022). Additionally, it is an air-borne disease and can be
transmitted easily, thus making it highly infectious. Because of its contagious nature,
TB remains a significant issue, with around 1 million active cases recorded in the
Philippines as of 2019 (World Health Organization, 2019).
Monitoring the treatment status and occasional progress of a patient is
important when combatting different diseases, including TB. Patients receive
treatment once diagnosed with the disease and are isolated in order to prevent
infection. This treatment usually lasts for at least 6 months, with a monthly check-up
with their doctor (Centers for Disease Control and Prevention, 2021). Despite the
need to monitor a patient’s progress, there are times when the patient does not
regularly update their doctor, drink their medicine, and even fail to show up for their
monitoring. Because of this, their treatment for TB is not as efficient as expected.
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Machine learning is a rapidly developing branch of Artificial Intelligence (AI). It
is a scope of computational science that focuses on the analysis and interpretation of
patterns and structures in the data for the AI to learn, make predictions, and many
more (NetApp, n.d.). This branch of AI can be found in search engines, email filters,
and even voice recognition (The Royal Society, n.d.). It can also be used for the
development of monitoring and filing systems.
The purpose of this study is to develop an application that will help monitor TB
patients from their homes and create a database that will show the status of certain
patients. The study aims to identify whether the application will be accurate,
efficient, and easy to use; whether it will display necessary information; and whether
the application will help with easy filing and patient profiling.
1.2 Significance of the Study
The utilization of Machine Learning in the development of an application
whether it’s able to properly determine and monitor TB patients.
This study will benefit various sectors and people are as follows:
Department of Health (DOH)
This study will benefit this department as our application is able to help keep
track, monitor, and profile TB patients and help collect data much easier and
convenient.
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Philippine Tuberculosis Society, Inc
This study will benefit this organization in various ways as our application is
able to help monitor and keep track of TB patients as well as providing further
significant information about the disease itself.
Hospitals/Medical Centers
This study will benefit these places as it’ll give them a much easier time to help
keep track of TB patients encountered everyday as well as to monitor them of
proper medicine intake and regular check-ups.
Pulmonologists
This study will benefit these medical professionals as our application will be able
to help record data and keep track of TB patients inputted by them and through
the doctors.
Community
This study will benefit the community for it will be a much easier and
convenient way to identify TB patients and a way for them to keep track and
monitor their own current status and well-being.
1.3 Statement of the Problem
Tuberculosis (TB) is a serious issue in the Philippines. As a way to combat
the disease, it is important to provide and monitor the treatment of a patient.
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However, monitoring a patient can be difficult, especially when they are diagnosed
with an easily transmitted disease. In order to ease the situation, an application for
monitoring patients and filing that is accessible to both the patient and doctor will be
developed.
In order to ensure the accurate and efficient performance of the
application, the study aims to answer the following questions:
1. Will the application be accurate, efficient, and easy to use?
2. Does the application display and label the necessary information, namely the
progress of the patient, the information the user will input and whether their
treatment is progressing smoothly?
3. Will the application properly organize files of TB patients and make it easily
accessible to their doctors?
1.4 Research Hypothesis
The following are the hypotheses formed:
1. The application will not be accurate, efficient, and easy to use.
2. The application does not display and label the necessary information, namely
the progress of the patient, the information the user will input and whether
their treatment is progressing smoothly.
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3. The application will not properly organize files of TB patients and make it
easily accessible to their doctors.
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1.5 Conceptual Framework
The study aims to develop an application that will be able to monitor the
tuberculosis (TB) patients easier through machine learning and to determine the
accuracy of the system created.
Figure 1. Framework of the Study
The figure above shows the relationship between the independent and
dependent variables of this study. The algorithm used to file/monitor TB patients,
together with the programming is the study’s independent variable (IV). Meanwhile,
the application’s feasibility and effectiveness to file the patient’s conditions is the
dependent variable (DV).
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1.6 Scope and Limitations
This study will focus on developing a machine learning-based application for
filing TB patients by programming the application. This study aims to implement an
application that will be able to locate and identify patients who have completed or
uncompleted their medications that would improve the efficiency of filing in hospitals
and health centers. The study does not aim to produce a physical machine nor make
it commercial. The intended program and application will not be made publicly
available and will serve as a temporary program, open to future modifications
dependent on the successful validation of the study.
The programming aspect of the project will be carried out using the Python
programming language. To evaluate the feasibility of the application, an observation
analysis will be conducted through changing the time to assess whether the
application does work.
1.7 Definition of Terms
Tuberculosis (TB) Patients
The diagnosed patient that the program seeks to monitor and file.
Algorithm
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The independent variable of the study, the set of instructions to be utilized to
analyze the patient’s data and provide valuable insights, enhancing the
effectiveness of the system. Several algorithms are available for machine
learning.
Python
The programming language to be used in the development of the application.
Machine Learning
The common branch of AI used to create the application for filing with the use of
data sheets provided by medical professionals.
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Chapter II
REVIEW OF RELATED LITERATURE
2.1 Conceptual Literature
Tuberculosis
Tuberculosis (TB) is a potentially fatal illness that mostly affects the lungs.
Mycobacterium tuberculosis is the kind of bacteria that causes tuberculosis (TB)
(Mayo Clinic, 2023). Tuberculosis spreads quickly in places where people
congregate or live in close quarters. The general symptoms of Tuberculosis
include feelings of sickness or weakness, weight loss, fever, night sweats,
coughing up blood or mucus, chest pain, pain with breathing or coughing, and
fever. TB sickness symptoms vary based on the part of the body affected
(Centers for Disease Control and Prevention, 2021). The most often used therapy
for active TB Isoniazid is INH in combination with three other drugs—rifampin,
pyrazinamide, and ethambutol. Although you may feel better within a few weeks
of taking the medications, treating tuberculosis takes significantly longer than
treating other bacterial diseases (American Lung Association, n.d.). Current TB
treatment monitoring recommendations rely on sputum and culture conversion,
which have low sensitivity and long turnaround times, pose a biohazard risk, and
are prone to contamination, undermining their utility as clinical treatment
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monitoring tools and for drug development (American Society for Microbiology,
2022).
Machine Learning
Machine learning is a continuously evolving branch of Artificial Intelligence
wherein the system makes use of data and algorithms to learn on its own and do
certain tasks (IBM, n.d.). In contrast to other systems, machine learning
algorithms utilize computational methods to learn from data, instead of
depending on an ingrained equation (MathWorks, n.d.). It is in the field of
computational science which involves the analysis and interpretation of data
patterns to support learning, reasoning, and decision-making, without the
involvement of humans (NetApp, n.d.).
2.2 Related Studies
FOREIGN STUDIES
A study titled "What We Know About Tuberculosis Transmission: An
Overview," conducted by Churchyard et al. aims to provide a comprehensive
understanding of tuberculosis transmission and recommend targeted interventions.
The study presents a simplified cascade model of transmission, highlighting the
sequential events from the source case generating infectious particles to susceptible
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individuals becoming infected. By targeting each stage of the transmission cascade,
interventions can effectively disrupt tuberculosis spread, leading to a decline in
incidence and mortality rates. This study lays the groundwork for future articles
exploring specific aspects of tuberculosis transmission, offering valuable insights for
combating this global health issue.
A study titled "Drivers of Tuberculosis Transmission," by Mathema et al. aims
to explore the complex factors influencing the transmission of tuberculosis (TB)
within communities. The researchers discuss the challenges in measuring TB
transmission and highlight various approaches used to estimate the probability of
recent transmission and the fraction of TB cases attributed to recent transmission in
populations. These approaches include analyzing tuberculosis case notifications in
young children, trends in tuberculin skin tests and interferon γ–release assays, and
the use of M. tuberculosis whole-genome sequencing to track transmission patterns.
The study emphasizes the significance of factors such as the prevalence of TB, living
and working conditions, and the effectiveness of healthcare and public health
systems in identifying and treating infectious cases. By providing an overview of
these factors and measurement tools, the study aims to bridge knowledge gaps and
contribute to the understanding of TB transmission dynamics.
Wang et al. conducted a research study with the title of "Using Electronic
Medication Monitoring to Guide Differential Management of Tuberculosis Patients at
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the Community Level in China," the study aimed to evaluate the acceptance and
effectiveness of an electronic medication monitor (EMM) for supporting TB patient
adherence to treatment in a community setting. The study was conducted in
Zhenjiang City, Jiangsu Province, where universal implementation of directly
observed therapy (DOT) was not feasible. Patients were given the option to use the
EMM or receive DOT. The EMM stored a month's supply of anti-TB drugs, and patient
adherence was monitored monthly. Patients with poor adherence were switched to
DOT. The study included 231 TB patients, with 154 completing the treatment course
using the EMM. The median adherence rate was 99.3%. Healthcare workers found
the EMM acceptable, although it moderately increased their workload. Through the
EMM program, the workload of community physicians significantly reduced by
reducing patient visits. The study highlights the potential of EMM for differential TB
patient management at the community level in China, but further operational
research is needed before scaling up the technology.
A study conducted by Wang et al. entitled "EMM Implementation for TB
Patients in China" assessed the use of an electronic medication monitor (EMM) for
self-administered TB treatment. Out of 2,227 individuals, 1,810 (81%) were eligible
for EMM, and 1,314 (73%) used it during their treatment. Based on EMM data, 134
patients (10%) required a shift to directly observed therapy (DOT). Factors
associated with not using EMM within the first month included age, employment
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status, tuberculosis pleurisy, and previous treatment. The study emphasized the
need to ensure adherence and provide clear guidelines for managing missing EMM
data. EMM implementation holds promise for enhancing TB treatment and control in
China.
A study titled "Evaluation of Mobile Application for TB Management in Tianjin,"
by Li et al. assessed the effectiveness of a mobile app in improving adherence and
patient outcomes. Data from the app and TB Information Management System were
analyzed using logistic regression. App users had more regular check-ups, and
33.28% showed regular drug intake. The overall drug intake rate was 84.84%. Poor
adherence was linked to tuberculosis pleurisy and prior treatment, while residents
had better adherence. The study highlights the app's positive impact but suggests
additional measures for better medication compliance.
A study entitled “An artificial intelligence approach to monitor student performance
and devise preventive measures” was conducted by Khan et al. in 2021. The study
aims to monitor students’ academic progress with machine learning, as well as
inform their respective instructors to help improve the students’ grades at an early
stage. The researchers created a system by utilizing different machine-learning
algorithms. The results showed that the Decision Tree algorithm worked the best
compared to other algorithms. It was concluded that machine learning can indeed
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monitor student performance and suggest preventive measures to assist the
students with their struggles.
LOCAL STUDIES
A study entitled "The social determinants of Tuberculosis in the Philippines"
was conducted by Flores et. al in 2022. The study states in the Philippines, where
nearly 10 million people reside in urban slums, social determinants are also major
drivers of tuberculosis endemicity. The local 2019 TB Program Review showed how
vulnerable populations—the urban poor, people living with HIV, and people
deprived of liberty—are more susceptible to infection and worse treatment
outcomes. The study contributes to the importance of the study because of the
frequent victims of Tuberculosis.
Calderon et al. (2022) conducted a study titled "Innovating tuberculosis
prevention to achieve universal health coverage in the Philippines." The goal of the
study was to make a significant contribution to tuberculosis (TB) elimination by
advocating for the integration of innovative approaches such as tele-contact
investigation (TCI), mathematical modeling, and participatory governance in TB
preventive treatment (TPT). The findings of this study emphasize the importance
of adapting innovative strategies to address TB elimination and improve TB
preventive treatment, proving the importance, timeliness, and valuable insights for
our current research.
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A study entitled "Barriers to tuberculosis care in the Philippines" was
conducted by Dychiao et.al in 2022. The paper reported a discrepancy between
expected and reported tuberculosis cases during the COVID-19 pandemic. This
study aimed to examine the barriers to tuberculosis care in the Philippines amidst
the COVID-19 pandemic. Using a combination of quantitative and qualitative
research methods, the researchers investigated factors such as public perceptions,
healthcare access, and the impact of the decentralized COVID-19 response on
tuberculosis surveillance and control measures. The study revealed a significant
decline in tuberculosis case notification, with a decrease of 78.7% following the
implementation of community quarantine measures. Public perceptions about
respiratory illnesses, limited healthcare access, and the decentralized COVID-19
response were identified as major hindrances to tuberculosis care. Furthermore,
the study highlighted the projected increase in tuberculosis incidence and deaths
due to the effects of COVID-19. The National Tuberculosis Program (NTP)
interventions, including video-observed treatment and digital adherence
technologies, were found to be promising, resulting in a 75% relative reduction in
loss to follow-up after 6 months of treatment. However, these interventions were
limited to only two regions and remained inaccessible to the majority of Filipinos.
The study emphasizes the need for a centralized strategy to enhance surveillance,
service delivery, and the overall reduction of the tuberculosis burden in the
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Philippines. This study helps the current one as it points out the need for a system
that monitors and keeps track of TB patients in the Philippines amidst the current
barriers and problems it faces.
2.3 Synthesis
The related studies above include a variety of information that have similar and
different results or components used compared to our study. The study of
Churchyard et. al (2017) and Agyeman et al. (2017) lays the groundwork for future
articles exploring specific aspects of tuberculosis transmission, offering valuable
insights for combating this global health issue and offers general education to
healthcare professionals and the public which promotes awareness of its prevention
and management strategies. Furthermore, The study of Li et. al (2021) included data
from the app and TB Information Management System were analyzed using logistic
regression. App users had more regular check-ups, and 33.28% showed regular drug
intake. This shows the importance of a monitoring app and why the logistic
regression algorithm was used. Additionally, the study of Mathema et. al discusses
the challenges in measuring TB transmission and highlight various approaches used
to estimate the probability of recent transmission. These challenges include analyzing
tuberculosis case notifications in young children, trends in tuberculin skin tests and
interferon γ–release assays which bridge knowledge gaps and contribute to the
understanding of TB transmission dynamics. The studies of Wang and Shewade et. al
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utilized electronic medication monitors (EMM) for supporting TB patient adherence to
treatment in a community setting. Healthcare workers associated with the study
found the EMM acceptable and states EMM implementation holds promise for
enhancing TB treatment and control which justifies the application of EMM in our
study.
2.4 Justification of the Study
Being one of the leading causes of diseases in the Philippines, the study will
be conducted to utilize machine learning in the creation of an application to monitor
and keep track of TB patients among medical centers and hospitals for medical
personnel and TB-affected patients to use. The preceding foreign and local studies
disclosed different and consistent findings about the lack of monitoring and
evaluation of TB patients and the need for one. The variables are with similarities to
the present study, specifically, with the use of Python as the computer program, and
data set to monitor and evaluate. The researchers wanted to compare the
differences between each study, taking into account the gaps and recommendations
of each supporting study that the researchers wish to enhance and address.
Numerous foreign and local studies including the study of Li et al, Khan et al
(2021), and Wang et al have correlations to the present study because they were
able to highlight the need to approach the innovation world in the fields of computer
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programming language, mathematical modeling, tele-contact investigation. This laid
the groundwork for the creation and the groundwork for the variable of the paper.
Taking into account the similarities of the supporting studies to the present,
there are gaps and recommendations that the researchers would like to improve.
The related literature entitled “EMM Implementation for TB Patients in China”
ensured the efficiency of an electronic medication monitor, unlike the main study, it
does not have various algorithms to compare to.
Based on previous studies, results, and discussions, the researchers decided to
perform this study to create an application using machine learning to enhance cancer
the efficiency of the health center and hospital's way of profiling, monitoring, and
ultimately tracking down the progress of each patient. Using machine learning, a
method that is widely known allows software applications to become accurate at
predicting outcomes. The study is considered a cost-efficient and efficient way to
monitor and file TB patients because an application beats the traditional way of filing
patients through papers. It is a study unlike the given related literature as the study
focuses on the accuracy and precision of the application's ability to file and monitor
TB patients through machine learning.
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Chapter III
METHODOLOGY
3.1 Research Design
The study will utilize the One-Group Posttest-Only Design as it is the most
fitting research design. This will help determine whether each algorithm used has a
significant difference from each other and whether the system is capable of
effectively monitoring the treatment progress of a TB patient, along with creating an
organized database to be used by doctors and medical staff. The table below
represents the tabulated results of the study, wherein “X” serves as a placeholder for
the values to be inputted by the researchers after the experimentation proper.
VARIABLES POSTTEST
(ALGORITHM ACCURACY PRECISION RECALL F-SCORE
USED)
Decision Tree X X X X
k-Nearest X X X X
Neighbors
Artificial Neural X X X X
Network
Table 3.1 Research Design
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3.2 Materials and Procedures
Acquiring the Data
The data to be used for the training and testing of the system will be
obtained from Our Lady of Guadalupe Medical Specialists Clinic in Imus, Cavite.
The hospital will provide the data on 200 patients’ weight, cough status,
presence of colds, fever, rashes, and abdominal pain.
Data Preparation
The acquired data will then undergo a preparation stage involving data
cleanup, data normalization, and variable selection. Data cleanup will fill in null
values, while null values that cannot be filled will be eliminated. This is followed
by data normalization where the data will be converted to a form that is easier
for the algorithm to understand and analyze. Afterwards, a target variable will be
selected. The target variable or the goal of the application for the study is to
identify whether the progress of the patient is progressing well.
Algorithm Selection
After the data is prepared, the machine learning algorithms that the
program will use are selected. These are the Decision Tree algorithm, k-Nearest
Neighbors algorithm, and the Artificial Neural Network Algorithm.
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System Programming
After the algorithms and data set is ready to be used, the application’s
programming will be conducted. The programming will make use of the Python
programming language, using the Python 3.11 compiler. The data set and
algorithms will be inputted into the program. Additionally, through programming,
the application will also feature a filing system for medical staff.
Model Training
The ten-fold cross-validation method will be used to train the model. The
data set will be randomly divided into nine parts for the model’s training, while
one part will be for its testing. This process will be repeated ten times with
different randomly divided parts. In order to avoid bias, ten randomly selected
information of patients will be set aside for testing alone.
Model Testing and Data Evaluation
After training the model, the application will be run. The data set aside will
then be used for testing the system and the conclusion to be presented by the
program will be evaluated in the confusion matrix, either a True Positive (TP),
False Positive (FP), or False Negative (FN). This will be tested for each of the
algorithms used by the program. The results will then be computed using the
derivatives of the matrix, namely its accuracy, determined by the formulas
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accuracy = (TP+TN)/(TP+TN+FP+FN), precision = (TP)/(TP+FP), recall =
(TP)/(TP+FN), and f-score = 2*(precision*recall)/(recall+precision).
Furthermore, the smooth navigation and intended use of the application will also
be tested by simply imputing the data for testing and observing whether the
correct data is presented by the application.
Application Testing
After the first testing phase of the application. It will be sent to 5 hospitals,
namely St. Dominic Medical Center, Central East Asia Medical Center, Our Lady
of Guadalupe Medical Specialists Clinic, Bacoor City Health (Salinas) – DOTS, and
Bacoor Doctors Medical Center for a test run. The application will be used to
monitor TB patients for a month. Afterwards, the mentioned hospitals will be
answering a checklist prepared by the researchers in order to assess the
performance of the application.
3.3 Experimental Design
The table below shows the study’s experimental design:
VARIABLES EXPERIMENTAL GROUP

Algorithm Used Decision Tree k-Nearest Artificial Neural
Neighbors Network
Programming Python Python Python
Language Used
Number of 10 10 10
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Experimental
Repetitions
Table 3.2 Experimental Design
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3.4 Experimental Flowchart
The flowchart below shows the processes that will be followed throughout the
experimentation phase in order to ensure the validity and success of the experiment.
Acquiring the Data Set
Data Pre-processing
Algorithm Selection
System Programming
Model Training
Model Testing and Data Evaluation
Application Testing
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3.5 Statistical Treatment
The study will make use of the T-test statistical treatment in order to
determine the means or the difference between the results provided by the doctor’s
data and the results presented by the application. This will provide a t-value and p-
value, along with its level of significance, allowing the researchers to determine
whether the study’s results are significant.
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References
Agyeman, A., Ofori-Asenso, R. (2017). Tuberculosis—an overview.
https://www.researchgate.net/profile/Richard-Ofori-Asenso/publication/
309666774_Tuberculosis_-_an_overview/links/581c39d808ae40da2caa44a5/
Tuberculosis-an-overview.pdf
Calderon, J., Perry, K., Thi, S, S., Stevens, S. (December, 2022). Innovating tuberculosis
prevention to achieve universal health coverage in the Philippines.
https://www.sciencedirect.com/science/article/pii/S2666606522002243
Churchyard, G., Kim, P., Shah, S., Rustomjee, R., Gandhi, N., Mathema, B., Dowdy, D.,
Kasmar, A., Cardenas, V. (October, 2017). What We Know About Tuberculosis
Transmission: An Overview.
https://academic.oup.com/jid/article/216/suppl_6/S629/4589582
Flores, G., Alberto, I., Eala, M., Canal, J. (January, 2022). The social determinants of
tuberculosis in the Philippines. - The Lancet Global Health - socioeconomic factors
and determinants of tb in the ph.
https://www.thelancet.com/journals/langlo/article/PIIS2214-109X(21)00516-7/
fulltext
Jones, A. B., & Brook, C. D. (2011). Sample print book title. Publisher.
Li, X., Pang X., Zhang, F., (August, 2021). Evaluation of Mobile Application for the
Management of Tuberculosis Patients in Tianjin During 2019–2020.
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https://www.dovepress.com/evaluation-of-mobile-application-for-the-
management-of-tuberculosis-pa-peer-reviewed-fulltext-article-PPA
Manyazewal, T., Woldeamanuel, Y., Getinet, T., Hoover, A., Bobosha, K., Fuad, O.
(January, 2023). Patient-reported usability and satisfaction with electronic
medication event reminder and monitor device for tuberculosis: a multicentre,
randomised controlled trial.
https://www.thelancet.com/journals/eclinm/article/PIIS2589-5370(22)00549-1/
fulltext#secsectitle0010
Mathema, B., Andrews, J., Cohen, T., Borgdorff, M., Behr, M., Glynn, J., Rustomjee, R.,
Silk, B., Wood, R. (October, 2017). Drivers of Tuberculosis Transmission.
https://academic.oup.com/jid/article/216/suppl_6/S644/4589580
The Corporation. (2012). Company brochure: Available online. Retrieved August 27,
2012, from https://www.corporationxyz.brochure/pdf
Walker, A. (2019, November 14). Germany avoids recession but growth remains
weak. BBC News. https://www.bbc.com/news/business-50419127
Wang, N., Shewade, H., Thekkur, P., Huang, F., Yuan, Y., Wang, X., Sun, M., Zhang, H.
(April, 2020). Electronic medication monitor for people with tuberculosis:
Implementation experience from thirty counties in China.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7190174/
Wang, N., Zhang, H., Zhou, Y., Jiang, H., Dai, B., Sun, M., Li, Y., Kinter, A., Huang, F.
(October, 2019). Using electronic medication monitoring to guide differential
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management of tuberculosis patients at the community level in China.
https://bmcinfectdis.biomedcentral.com/articles/10.1186/s12879-019-4521-2
Xiang, E., Cooper, F., Wilson, G. H., & Liang, I. (2012). Sample title: Of an invented
journal article. Citations, 14(7), 34-41. https://doi.org/10.1056/j.cit.2012.08.034
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APPENDICES
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Appendix A
BUDGET PLAN
Materials/ Unit / Quantity Unit Cost Total Cost
Test
Programmer 1 Php 500 Php 500
TOTAL COST: Php 500
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Appendix B
PROJECT DATA BOOK
Project Title: TBantay: DEVELOPMENT OF A TUBERCULOSIS PATIENT MONITORING

APPLICATION USING MACHINE LEARNING
Researchers: Deado, Angeles, Baldago, Ramos, Berbon, Jarabelo
Summary of the Activities/ Accomplished Tasks
Date Activity Undertaken Persons Involved Remarks
05/26/23 Construction and Deado, Angeles,

Conceptualization Baldago, Ramos,
of Research Title Berbon, Jarabelo
05/27/23 – Background Deado, Angeles,

05/28/23 Research About Baldago, Ramos,
Selected Topic Berbon, Jarabelo
05/29/23 Writing of Chapter Deado, Angeles,

1 Baldago, Ramos,
Berbon, Jarabelo
05/30/23 – Writing of Chapter Deado, Angeles,

05/31/23 2 Baldago, Ramos,
Berbon, Jarabelo
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06/01/23 – Writing of Chapter Deado, Angeles,

06/02/23 3 and Finalization Baldago, Ramos,
of Paper Berbon, Jarabelo
06/03/23 – Creation of Display Deado, Angeles,

06/04/23 Board Baldago, Ramos,
Berbon, Jarabelo
Appendix C
PROJECT APPROVAL FORM
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Appendix D
CURRICULUM VITAE
PERSONAL INFORMATION
Name: Claire Eugene L. Deado
Date of Birth: May 18, 2008
Age: 15
Address: Blk 2A Lot 17, Chesapeake Village, Buhay na
Tubig, Imus, Cavite
Contact Details:
E-mail – claire18deado@gmail.com
Cellphone Number – 0961 159 5238
EDUCATION
Elementary: Academia de Julia Victoria
Secondary: Bacoor National High School Main
AWARDS AND RECOGNITIONS

 2021 Division Science and Technology (DSTF): Science Investigatory Project (Life
Science) – Best Paper and Best Poster
 Grade 8 Online Quiz Bee – 3rd Place
 2021 Research Congress:
- 1st Place, Best Paper - 1st Place, Best Group Presenter
- 1st Place, Best Powerpoint
- 1st Place, Best Research Proposal - 2nd Place, Best in 3D Brochure
- 2nd Place, Best in Video Presentation
 Consistent With High Honors
_______________________________________________________________________________
41
Name: Andrea Kate G. Angeles
Date of Birth: July 3, 2007
Age: 15
Address: Blk 10 Lot 11, Ivory St., Diamond Village,
Salawag, Dasmarinas, Cavite
Contact Details:
E-mail – angelesandrea1203@gmail.com
EDUCATION
Elementary: Salawag Merryhills School

 Consistent Honor Student
_______________________________________________________________________________
42
Name: Adam T. Baldago
Age: 14
Address: Blk 2 Lot 1, Phase 1-A Navarre Belazzona,
Molino III, Bacoor, Cavite
Contact Details:
E-mail – adambaldago08@gmail.com
EDUCATION
Elementary: St. Dominic College of Asia
St. Jerome Emiliani Institute

- 1st Place, Best Paper - 1st Place, Best Group Presenter
- 1st Place, Best Powerpoint
_______________________________________________________________________________
43
Name: Keziah Ashley I. Jarabelo
Date of Birth: September 20, 2008
Age: 14
Address: Blk 9 Lot 28, Greentown Villas 1, Mambog III,
Bacoor, Cavite
Contact Details:
E-mail – keziahjarabelo@gmail.com
EDUCATION
Elementary: University of Perpetual Help System DALTA
Statefields School Inc.

_______________________________________________________________________________
44
Name: James Lemuel C. Ramos
Date of Birth: December 3, 2007
Age: 15
Address: Blk 15 Lot 22, M. Aquino St., Georgetown
Heights, Molino IV, Bacoor, Cavite

Contact Details:
E-mail – jamesramos1237@gmail.com
EDUCATION
Elementary: George Mueller Christian Academy
Secondary: Bacoor National High School - Main

_______________________________________________________________________________
45
Name: Rafael Athrun DP. Berbon
Age: 15
Address: Blk 5 Lot 45 Ph 2 Sapphire Street Maryhomes
Subdivision Molino 4 Bacoor, Cavite
Contact Details:
E-mail – athrun.berbon@gmail.com
EDUCATION
Elementary: Maria Mae Academy Inc.
Likha Molino 4 Elementary School

_______________________________________________________________________________

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BACOOR NATIONAL HIGH SCHOOL MAIN

MOLINO I, CITY OF BACOOR, CAVITE

TBantay: DEVELOPMENT OF A TUBERCOLOSIS

A RESEARCH PROJECT PROPOSAL

Deado, Claire Eugene L.

Special Science Curriculum

Mr. Richard L. Nocillado

Background of the Study 5

Significance of the Study 6

Statement of the Problem 7

Scope and Limitations 10

II. REVIEW OF RELATED LITERATURE 12

Justification of the Study 19

Materials and Procedures 23

Appendix A Budget Plan 32

Appendix B Project Data Book 33

Appendix C Project Approval Form 34

Appendix D Curriculum Vitae 35

Thank you for your patience and guidance.

assisting and helping us.

protecting us, giving us enough strength and energy to overcome hardships we

1.1 Background of the Study

Tuberculosis (TB) is a serious, potentially life-threatening infectious disease

caused by a bacteria called Mycobacterium tuberculosis. It is a disease that primarily

kidneys (Cleveland Clinic, 2022). Additionally, it is an air-borne disease and can be

Philippines as of 2019 (World Health Organization, 2019).

Monitoring the treatment status and occasional progress of a patient is

important when combatting different diseases, including TB. Patients receive

monitoring. Because of this, their treatment for TB is not as efficient as expected.

Machine learning is a rapidly developing branch of Artificial Intelligence (AI). It

is a scope of computational science that focuses on the analysis and interpretation of

development of monitoring and filing systems.

1.2 Significance of the Study

The utilization of Machine Learning in the development of an application

whether it’s able to properly determine and monitor TB patients.

Department of Health (DOH)

Philippine Tuberculosis Society, Inc

significant information about the disease itself.

keep track of TB patients encountered everyday as well as to monitor them of

proper medicine intake and regular check-ups.

monitor their own current status and well-being.

1.3 Statement of the Problem

Tuberculosis (TB) is a serious issue in the Philippines. As a way to combat

the disease, it is important to provide and monitor the treatment of a patient.

In order to ensure the accurate and efficient performance of the

application, the study aims to answer the following questions:

1. Will the application be accurate, efficient, and easy to use?

treatment is progressing smoothly?

accessible to their doctors?

1.4 Research Hypothesis

The following are the hypotheses formed:

1. The application will not be accurate, efficient, and easy to use.

their treatment is progressing smoothly.

easily accessible to their doctors.

1.5 Conceptual Framework

accuracy of the system created.

Figure 1. Framework of the Study

dependent variables of this study. The algorithm used to file/monitor TB patients,