Pa Tho Physiology of URTI

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Lack of Vaccination

Smoking Weakens the immune system

PATHOPHYSIOLOGY OF UPPER RESPIRATORY TRACT INFECTION


Living in crowded conditions Poor Hygiene

Poor Immune System Too hot or too cold environment

The risk of contracting pathogens

Pathogen invades the host through the upper respiratory tract

Pathogen infects different parts of the URT Rhinorrhea (Runny Nose) Body increases nasal discharges Pathogen triggers cellular responses Cells in the Reticuloendothelial system undergoes phagocytosis

Inflammation of the Nasal and Sinus Mucosal Membrane

Nasal and Sinus Congestion (Stuffy Nose)

Macrophages releases pyrogenic cytokines

Mild Difficulty of Breathing

Narrowing of the airways

Stimulation of Cough reflex

Stimulation of the Hypothalamus to elevate the thermostat set-point

Fatigue

Decrease supply of oxygen

Cough Body initiates heat conservation

Mild Body Malaise

Increase respiration

Hyperthermia

Pathogen infects different parts of the URT

Pathogen infects the Pharynx

Pathogen infects the Larynx

Pathogen infects the Tonsils

Inflammation of the Pharynx (Pharyngitis)

Inflammation of the Larynx (Laryngitis)

Inflammation of the Tonsils (Tonsillitis)

Difficulty of swallowing

Sore Throat

Hoarse Voice

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