Followup on Homework

• Gradient non-Linearities

20
Principles of MRI

Frequency, kHz
10
EE225E / BIO265 Actual Gradient

0
Lecture 07

-10
Instructor: Miki Lustig
Linear Model
UC Berkeley, EECS

-20
-20 -10 0 10 20
Position, z, cm
M. Lustig, EECS UC Berkeley M. Lustig, EECS UC Berkeley
1 2

Followup on Homework
• Gradient non-Linearities
Before correction Grad-warp correction

M. Lustig, EECS UC Berkeley M. Lustig, EECS UC Berkeley

3 4
 5 6

M. Lustig, EECS UC Berkeley

7 8
 9 10

tic
( )

11 12
MR Physics Spin, Magnetic Moment and Magnetization

• Ch. 4 • Nuclei with Odd # protons/Neutrons

posses spin angular momentum

S = ~Iˆ
• Associated with S is a magnetic
moment

µ = Ŝ = ~Iˆ
1H

M. Lustig, EECS UC Berkeley M. Lustig, EECS UC Berkeley

13 14

Demonstration of Magnetic Resonance Spin, Magnetic Moment and Magnetization

• In a strong magnetic field B0, spins align with B0
giving a net magnetization
• Magnetic Moment is produced
X
• M= µ

B0

M. Lustig, EECS UC Berkeley M. Lustig, EECS UC Berkeley *Graphic rendering Bill Overall
15 16
 M. Lustig, EECS UC Berkeley M. Lustig, EECS UC Berkeley
17 18

Magnetization

• Magnetization:
PNAS September 2, 2003 vol. 100 no. 18 10158-10163

N 2 2
~ Iz (Iz + 1)B0 1

M0 = MW 0.8
electron

Polarization
linear 3kT linear
0.6

0.4
proton

carbon

quadratic 0.2

0 -3 -2 -1 0 1 2
10 10 10 10 10 10
Temperature (K)

Slide: Simon Hu, UCSF

M. Lustig, EECS UC Berkeley M. Lustig, EECS UC Berkeley
19 20
M. Lustig, EECS UC Berkeley M. Lustig, EECS UC Berkeley
21 22

M. Lustig, EECS UC Berkeley M. Lustig, EECS UC Berkeley

23 24
 Susceptibility Mapping
• Indirectly can be observed

Diamagnetic Levitation example:

M. Lustig, EECS UC Berkeley M. Lustig, EECS UC Berkeley http://mri.kennedykrieger.org/nationalresource/trd2.html

25 26

M. Lustig, EECS UC Berkeley M. Lustig, EECS UC Berkeley

27 28
Precession!

~ +µ
S ~ ) Precession
~ +B
Solution: ω= |B|

dM~
~ ⇥ B
=M ~
dt
M. Lustig, EECS UC Berkeley
29