la _ Alkalets ¢ — Mean alkal? ltke ee All organi boner enolaled from plonls Conighnallee defined > keent konigs (\eg0) —> alkalords ratura lta eontoin Q courting ongania. booes whieh pereidtre. rand: Tes dedinttfern ambraces % aompourds . ladon bure« Arkolerds — Netural plort}- compourds havi borPe_ Gharoatore. and contatatng— one N atom in a pan oe ae of plant olkalards + Boste dhaxoattar— Complex structure 5 Phestelagiea! oe} for. + Plont ori ae Alt alkelotds are alkaline fr redurco bul alt alkaline» compourds ate not alkoloths. lrtlod numbere ofSSE? _ Frlenetion of atkolbrds Alkale?d aree Unveltsy- Sourd In Ane peods , weal, waves ore bark. of the plords. Prey ea ee Mle Orda crc Glort- owkds , Cocotte act, oxolte. oid. , malie creo ocfd , act , -barclente. act > Plant deed, _ Sil, _Btkeocltion , purthond power ath etl? ea veh eaeg Firat solvert\ deatilla PastS tod Eeloahon Sip Atkalefd/ <= OS So a a with. al 4-7 hee Acluble salts CHCl, Michurae of throwelgorhte alkolord> Rare ofto ohkalords (on Stise barer) iia °nd lecture of Atkalods 2... 4-03-9023 _ Grerera) propedter of alkalerds %.— Bile ‘lode, optteally: aetire Ce, Se ton, —olonless , ngetallline. , mon—Wolodt lo solr . ¢ ' - z sto, [b,0, — driscluble Fru, wodlors , but Aoluble te eet de md /'y { s bowe abkelerd —Imetd 5: roluble fry nadlere — Alleles aartafa ob teat one’ rebrg- f the éompourd.. TeleeHon. of- allealord 2 J 2a Be Phoaphatunettie ooh dye Snécluble predkptot Alkaloids Ors Gros pho dlyoderte- acd om lett praca ocd Mes + a mt) ay ! cK hork’ a 7 5 ‘ Wagner’, reege eolore} . oft deasolved in KZ Ae! lege, PN Compe F Dregerdtersh6 rangort— @ ker Ty Hk Atealotds « Grems frsdtuble: preaipflede ustlin place aa Phesphetungste aetd, shosphomolubda a , yoda oetd . A ane usid fore debelton of- Slkabels. hese. teat,Gtenenal methods frre delaiemént heuclare. of alkaletds ¢ D Sb dornvs oxime roth haydre f enpiet- (Si nsvteg) Doors phenge helearsere: ith ee prenge hydiogs! eat Oxo group — ROH, We aldohye Seme.canbagone Seana fing aldehyde. group trie be oldehyde. ore Kidone. @ eer grep? a ean! be! detzotad by- ees wrethed — R—acott + ‘waco, ——> (Co= +R Bone «440 ro. oF} coy roupe korn be etfraded b Hale, tc ahidand ollalr ia Reo + NaoH ———> P—econta FH,o a rate Ceca) = 1 mel. of NaotP GD ose, — R- OR: lactone ——» estan rie form onneT; pm <) NO, dompound —> > ectourred Erle) R= ecou- Koo, R-cootia + Rot — © (Arne) R20 seta * goth, Racoon + hgh OD WOH AyG A oye ora ; L iH Pelorer2nodion of active melee Sere compound * | enenitines oltre. hydrager delermfaatton — ONS ——> R-OlM, emi, » RSH 7, R-o- Lit cM, roup 7% delocted mtn ayer Teer Sete > Roo + eHs (mtn? tabsle eel + “Agi Aleta! 5 Cua Da + Ag Stivere vthreata tere Podrde— A wele oS Otte, = A rete of AgTMctho: nal group — OMe Beisel wmelhed — OMe, ? oki HEM. met MEE, Agh woe |, Z® How, could wet: detorentre net hake re Aforey Qreup —0- 4H, -o— : 1 —o Ott, -O—y Sha oe N\qeen= San Cie NON BAL pee. obohatte group & preatent tn the ring then Bre? gitar 2. oa8d. tor| rlatntng 6 fame np. oF on ore doe ofecho! Diearchon gle etd»12-03-2023 Faneltoral roduc oS nittraegen mee Neen Ogi = by-me. group preserl ad wt 4 (CHB) gir ala a 7 fo (Hay 8 Cee oo Nha City ae oN matt aneee t_ Gennlg Maps | | A\kale?d : < ° » oltobelte- T pioiaaa Teton wth, met es od Ag ‘ adore. HI hte f ee =) . undo pressure. re te O—Me Bre U b \ i a)Hod pania Pe haualfine. weet loditen ancthed 2 yg 444 means hetarenssatte. nirge i opened - . Velercceyelfa! retry helnegeration Sahimatod hetreg den OS untaturoded Opa | esleyeg meee Ammrontum J reo? bo. reat = M20) Ans. proce Nreferce yelta_ wan \ty\ Novy ~ . tla ore | oq, Etore CatopHe- \agingerakiey | aT ~ Peleroaxe lie i / > relingy opered. i ® Lo Wl he Me : Q ort© Mes, 4 er, t2— wr 2 i “=> toy co)! : i ohg- i Fr ogo | Eto ets |Non Brea nA nvethod i tore texHor a arxyelfa. amen: ee LOOded tor with 1 Om» Tl ty eat © 5 0; MP oxtdad%n = ————> ae fea Medertate. cxlelfon ———>_ kK KM O4 + \igo nous orton —— kre, Or Hi, NP Ot ae OW tare BET le KB — ove is ~ ele Se thy Phaghal methed — vv-vin, TR, WMRL, Mans ace ErOgi0 CH « = 4,504, GO, HEOq4-04 — 202% Css Feabfor of Alkolord. & On the baits & the nature of tre nuchus prose @ Be Pheryplatialonsine groee eg ephidrtre incon, Ph—OH—CHetl, a hes GD Qyractt de ou enn CaP asso garding " hag Me @® Ryctdtne. ard pipatdire group 2Q- aoniine CN 3 Corners, << * Pyrola @ Rypelidine ord parting group ag. raclFne < y> te 7 | Ryrcol Fd&ac i bts gap&® Gutralire group j ©) cami nia al. oui Hwa all yout” open chee beteresexeltes Reig of yout” ope : “4 4 Tse quile lo sre ( Hofirann “Exhautine c weligiation mel hed How callelss orcesiabi fot) sue @) phehaiineuine. Qrexr prophase. . 4rdole. grove Gireairtrne i pastlb ayy SMeg — eg 1 4. EXN ra KMre ere Hig ore kp617,02 450, ct, 10 9 Zz ae NigetPrfa onfa Pyridine Oxtdolen wth . EEE Ro Ccon - = ale Kirby oN RE . ; “ SEE yutrelinfa. ocd oeBou Neobine contains Reyrekbine neebus , wR, Aide ebotr eonben Q— __ Fentfal 0 sheeeture oF ntecline . Cstt,N , atho ae onion, I+ Ntelfne. Bina! Fehon enon a a teriole. : Cele. Hougig— wagers methed { 4 : NfeoMyne LSet AT thse vot 60's ae Uurdarc” prtosoure Anh prove thet nfeolfne contatn N- wretrg? areup iyo \ Otte,Side chor could be ZS . N U CHa, = oN : : wes , ~ | eink of atlodlrrent could be ‘ etter 2 or & Ok, — OF — OH. CoH = \ ma | — ore aie (He i ty Ho eH OH, a 07 snd | Othe ae 0 Wphcorcengtd. : rbrongtde,fackine. eae a hegtrobeem ide aA, teot parebromtde aqueous H,S02, Dibreomcestinine— @yothoBn, N20 LODEAMO'— | ~ Yh, 20m/ 2504 dcetre, —t CH, NH | ~ lst" ad ee 1 Gre Cree be N Ora hie Steele Pycidine ot. mee | |BO oe Ey We Oe ° Bre, ( het “ Neeclire, => brbromabteontice: ' Bag with oe ool door . goo: + zy + OMe Ny Cty SN I + Cae \ + NU,IU-03-2023 Nieobfine at =—— Cot Syl a 2 Prob Where 0% the, position oh hme. Kee? Niacfine— behawes a Itt tod bone’ ond fore tse » orrercke mata! tedtda ton products , yt hai Redusah fe Neckline Bahia eshate nioolfre. Se CUNDOa ee Nb ag 7, DEE Croats bord oe DBE = oF @ poe a> Gro. bis. H ro. tf]GHyN Dee = oy - Baw HL yt \ How to ayrtinests_ntedline £ a, or feng elo os Ol Song! ag Bem Pie R005 Veh po west ort, cH an 2519— 64=202D > _NvccHine 3 tins Sts , ND : AT © + Vel 1 Sy me Me ON Me Roavertne ¢ Cop Hoy SOx SY fain optfeal Fracttre. alkalerd de a Gaaercary fodtde * Neato in he moleeake. Ts fo “Fords lec 4 CH Feure Come) Qroup present 26°C (Béiza} melted)t Pe a VOR, POL wus Oty ig PME NC) ’ 1 Me Me Me a han a BI eugene MER pcltnah FD ge banal VEH TL nw xl Baas. reachor ©) St will be occured tn less tem. & pre ite ete) R OD vats Pikedraieel) —SI os! Rapa! *eayentine Cold dil koird, — (2° oleshet) a ieee Gt kelore) | Coys we aH ase : i , 4p fon oo Rarer — keto group <— (os. oats’) 7 2-ome Group Ne cout SV in a <— dbase ootd cael(o in Sar as (AgH J) ang Le Etat parertee “When: yy shrie + Melohensifrt, 068 +; Rpcidire.—2., Hnteonkorerhie. ack. +6,4-dimethonsincyaroline—1— sonbow Te. ‘actd Uo) 7 Voratecin oa a Vonatnole Ko. iedicciay a) ~ Corie) Gh. 2 ee i oa, on McT | Noo}t eco Netcare OMe dtd OMe,Se Melohem®ptnic 068. eontatrs 4es0 =eMe- Qroup 7n Melahemtptota. ont (a dtsanborgfte. oat) ye ‘ordhs poston cao Norodrole | Vest OMe_ | (Aeiglaled) © th | 7 Reo | an on hedhetda, Cee ere R onthe posttfor] Cont tot a (ee ees Coo \ 4208") 1h (Ar anbaadaiide. 9. a Ly astfing Coot _acovt Coot ; ae 7 eoott WI ee | Ome on | thes Pe a thes form tes0 | de Sorent mono exter. wero ester.Ge cot sed gan) (_ostton off Coot} COo}- ors Ra Leptdinei + BOS 2022. : 4 voual test | contain -wo0o OMe. One — dcon » Wadi kMrO., Dinsetin trogptinctne.| reo. ort : ap en | Hae (Moar Te Melahemiptie, et Re : Gerd, ue iu - a depp Td el ord bol Naar Eo se So ioe . KMny Ma? esr © “own ener Risdeet ertogt Za,Structure, of Repaverctnc? ecol- DM Sedolfon oS verti oof.) abot Oma. tnd&oder The prasenec wef OMe ye roby ome TKD D Antebtor’ oS 6, t= dlertronge Moquirotire —(— cartbory fe a0td. trdtodes tre prasinien Of a a ond @® also i tas oho 2 te0 dompourds « “Tata ¢ otomcoS so Soup = 9412 =9)) W Back tren ano.Hon, Po 3 Show thiol; papaverine , dorlakns a eH — are ,Mad22- O-2093 aqueous Bally —_—__—__> Atropine (4) Trepra. actd + Tropic (ar obeohel) (D> npectfe_ reelodfon H 7 5 Pa aceon Thopine ond Ropinone (24-8 o>) \ QtcO, Qu,0H GeHigNo 3 rae “Top. acid ah aleehel ee Dibengsyltdtne or dexivod re lech Seo TreopProne P Crp, — a4,—a -a4,— “ ~ = Ec> ~Treopite oetd CeO, NH Hq Nemeth Paweetinfrtde ste Tees rector Intfecdes thot roping eomofan a NOE meting Pyrolrdtne (a aedOH, 4.CoH- Treoptinia -ackd 2 Pee _ tH. AHooH oxd ; . [Kp Oo 1 : Trophne re — Tropne \ Prete cH Ph “ ScHe lh eo oe =O - Cro, uf / a 1 Gt cooH | i Me, CH COOHou, 2 HH + 2 Potro heel Ph — CH= che oH uw Atropine 3 CH-Ph Tropine osha of hepa actd PH ge . Vy on + e —CH,OH4 CH, OF + ye bea Pen’ sHltton sen ra Ww| Co ore. pla ot Roof ooh on mretteg—- -o-— - (one: glare os rgd) : worn ‘ot pitts having: a ie oswis Sah a. Amine oatds ond protefns: 9-08-00 Pectofry yap Mixtune. of Amino’ ‘aetds ore anes soot - amino aid Rot Nera eee Way, loan? Staod tin of orntro adds Prine iaePd... CL —EeEPEe SO ae hat Bored. on humon ndictHen 1 x rent Se Obrerted Omnng aatds 1 Ryne = Coan) @© han-errerded onnine ockd.. , Ia Sem? — assorbiend ore Condit ono My: asrerbioN mag Sasordfat Naliney Werctre. Spelenetre, phe lolantre, Warteo nin Metntontae, } +naptophan, leptin, herdedete Non — essarttol 3 Alanine, Aercine, arcparctta. oetd , sae actd. dapanogne . s Sent erserfiad o ol pe eens & Gre, “gies prolinePeperdiiog of on the ne. of amino and contonerD Qreups present 3 |-© Norra! amino aetds (one —nm, group ond mabjetre alanine valine, leudtire,) Sone: Seco gious) ; © Acidic amrtro ac&da ened hy Group and two —ecott! greotip’) - cece acid Bhitairia. adid L- Coo — eH, aH ae” Geo StH, eH, ~CH = @oot}- Nt ; Nay BS @Binte’ ‘omtro aed Ceo ory group and one —eeoth)) Cryst, A fete) tyetee fot, aH, AH, GM CoH Nxt Whet do gou mean iby amene“aatd.D Write the alons teadton” ste ox amgle ond’ alruecherd.Crlyotre — A= Awkrooadte acl NM, — GH, eo Alarire, of, - amfroprioptonte. ackd cH, —CH—Ccott MH Lay” ante cents “6 thestlenitonte odd) €S- eH, — EM eoott Mth Serre Ce onto P-hetdicong, —preopfont oct) Ho eH, - ett —aoctt mE 2 Naline- (« ~amtrotse vali. o«td)) oe ty My Lenco demir feo rogreta. oe? ou, _ es 4H, ~ CH co otf das > ce| Groleuntre ( X-améno—P— meth n—salorte ye a, — CHa aot ees coor \ J a ty Mg Cystetre., Ca— awtro.

Orino- nitrete. ike } . et Amtro—oatl : tee ou, ' “Rae aoe 7 Terai 4 “ ee oe cf Ee © artkee . Oe rena tito i gaa an = a \ y ba ME Napier wT NON__09- 04-309 Arvlasi» oS Autre artda t helroly st wilh Mixduirte. oF amino acd Gistel ,, HN on Bo (OD, or engge Analysta (qurcltlalfve) — Common method —Son exchonge chacmalerophy Reoletn Exchange "ro Column: tx | ———— N Cie for exchange Coffer excharger o chrrowadomaphy) anton n ooechanger Codon oxeha on 1 ORC mae » Sulghonoded ‘) ed ate rors\ ‘root 7 Jin ee Tata (Rt ser oes i) Colum aorta, askdee | aod for exchanged 2 pene estan amen Or Oe ackds nosin Etudion with a Borekehs oS bulferc, solMton i Amine %tds ard. Menkigred ged wcthetre olled post-Hon Seg eS for —SeaSHT + RA RASC IRE LoL. Secon : . Neooy {2Sulphorafed. wa Polystyrene.AF Elution poston “BAHT: enaca Coe Cera Amine ocids. Rapore chromatography = Selmer ayer} | pan eH HO | | | | n-@u0H- AcOH - 4,0 Mobile proses — Boor we polvertt “Ore “YET air te Sg ART, OER Ninn = EXO Papes opr ye war, Color spt : shor9 . FA) Swat aa “teaGr ery, Amino, ackds, St One dirrorMornal .‘| Tees 'dtnertordal 5° ‘ two, solvent Agta fo unod hese: SE WH be une 2 ies. LOWRY Gre ET Att CO drag “pa era” Pope wr BIT THT | 6 Antro FP) Colountess ariyshlliac: compounds © gree bolubla We wodiere wD Sparing! soluble nr orgerie solve rds ) Geronohl Thee te opttentta oofee Conde)Sh Gin er of east one chiral excagh Geko tke aonlatr- ise “Ss ca Reactors dus +o amfno greee g QD Airs oatd reg Fron, Bere salt Qe sami Ronaty Hee > Ritts OL Inet gd yen) > eo Secor Ls,coel 2 @® Amfo: ocids sa Arcade exchotive CrtsQO is AE tette ——_> R-cH + CH Coot} + (Ubeo),O econ tego ace . 1 . NH R- Nn @Arsre oatd HNO N+ we adios’ oetd . Ny ou 4 2 NO R—déy 72> Ny + PR be ¢oon \ Coo Natu Ho if enfav 2s Ron toy R—wmt, Elbe RNY 202~O4-- 209% _ Reaetien “groups = Amino afd a N, + & —choloree%] — NH) — R- eH? > Ny + Rec a0 H- ™ aco ® Armies oe8ds te Soty afd + 0H Rea M2 ur, R : < Coot ae “OHS Coo ae Amino oe®h > Sal’ formalton _ Slt of heavy wcetal — obelale Compourd. oa EO tug 22 HON, et ie ° Nn WN eH - Mp een ) RG Her cP ° = 2 GR ie + CH,CHLOH a RA 3 cor Nae gy OctH,M2 a { 1H C Laat, p-of 2 “ > N Reduedf, , wr ug toon CO elten) enon wet Drool an pay ye BO SS ig ROH + Hy a UR as -+ Pot, oe 4 5 ° Co. 00, TH RE adaifal —wasrhsie Pale nes Reacltr due te beth amino ord tarbern! Glgsine —— Atpole rromert | Glynn ental Hrcoa al Cu > yalue) Pn pel Ex on an NY or y Ponere sat Cngadalline an, @, \ = > D Wigh mettirg- —_ GY ozduble in hylteronbory GD eoluble fro oquecees — Butter for+ : it + — at CH-NH, Coo pon, foo <2 ROH TM, 72C0 = Ks = arn aH corguugate bane cory ugele Dipolar . jo: ps ee ord. aon a eeectnal Sroclootete. pote} 2 pH od wREeR am ne oak deokE veal ards te te | olen roudrol ‘ Calendnbe Rel treclabrete, porn of -amiro ackds: aN —2— Cos = Uafh=2—coom Conjugorte. Bore asd * —2-aCoH. — teh 2-100 + Se — @r] xl Confugel Acid, @ EES Tap ana Moi 2 ces HN? 000 Hh , lel ti Dx. ae ~~ Pry & k, DU le)PA faease i pied Costeree sore, 0 DATA trartmum) ¢ 2) , @A ) tA rrartsrum Or PRraa net therga ts eptce ( KY - (a8) G lar 7 . ri . bt] > ae (HJ (et) Se 17 te (He? = —I — |e re gee = TB => gee 9 = eky + pKa ~. phe = (2 +a) ~~ a Clgefre » Pe = 24 ek, = O6O5—-O4-2.022 3g heebete | pH a dolore fon ran? mum , ofa} Pa bagfe oot vy oot ; & We —a— Re! bs} | | up BO aco } 4 c Cy, — Ceo en JN tao wes eB. Fn} Harm CORD, OF “goo Coon : Hl @ okt a pir = 2 S es ee bats oot, ge ¢< y Grime ag R Oe =e Clewere pH Te 000 oo HAN — i He fa she CHBeOO ee Ss % 8 HN Sto “7H Q4y—eco ~ete Amino o«fd “Rant pit eka TART SATE ard te volvo vcafar- tater pH pk valve wb ( Wagon ptt 5 ght (ponte) lower oH = > ptt C fon acid) Eater. oF laminc oefd __ heed, a75~debete ” 0,5 dtketopf pera gine Ora — 4 \ HK ony e Se —> | #4 = ai tt 2 BoD \ | , ro fre Sa “Ks We u ~ NH NTE “0 las eG aE Nor ter, @ Nee COoH } => R-ey ” Pr oNPh-N=@= Zz hmino afd He. @ Hydanben Yrdanes — (2 2 —Fretore. bedrock e. ik trlrdiin ranelfon ——> Smpordant fore Exon N finheg © eH —Coott on + HN GH 0° Ht a bo “ 4 Raene ne a erat mpourd G ebveti ee, " thong. Ananstltorn cate ee nang q wom GTB colo show ACT]tte coo cyt $6) o |e a CoG <3 —_ 9 05-2098? Exar Alvolotds a Proferns a ~ 2, Mai prefirary Prole®a % Greek We ke Prolefos “Zz y peat flan Strpla —? hydrelysts PYF, ambro ack Cong ated atlas — Amtno ac%+ Non amtno add “e Prooathelfe Qroup dered hadrolasn ge | “ ° ple + Conjugated proter