Zingiber - 22

THE EFFICIENCY OF ZINGIBER OFFICINALE NASAL SPRAY FOR ALLERGIC RHINITIS
Republic of the Philippines

Department of Education
Region III
SCHOOL DIVISION OF PAMPANGA

San Vicente, Lubao
The Efficiency of Zingiber Officiale Nasal Spray
For Allergic Rhinitis
The Efficiency of Zingiber Officinale Nasal Spray for Allergic Rhinitis
Gerald Jean Arcayos Dait
San Vicente National High School
Science Technology Engineering Mathe
March 2023

ACKNOWLEDGEMENT
The researcher would like to reach out our most profound appreciation to those
individuals who had made a difference in the completion of this study.
First and foremost, the researcher would like to give thanks to the Lord, our Almighty God for
the knowledge, intelligence, boldness, and strength to wrap up this research study. Also, for
giving the course this opportunity and involvement that gave us so much to learn, and we thank
you for the guidance all through the end.
The researcher would also like to express deep and sincere gratitude to our
research adviser, Mr. Hadjie Dagami for providing invaluable supervision, support, and
knowledge during the course of this research study. The researcher would also like to thank him
for his empathy, patience, and knowledge that he imparts unto us. It was agreat privilege and
honor to work and study under his guidance.
The researcher would like to express our sincerest gratitude and appreciation towards these
individuals who were with us from the start of our journey and to those individuals who lend
their assistance to make this research possible.
The researcher would like to thank and express appreciations to the respondents who willingly
helped with their full cooperation which has made the research study achieve its smooth
completion. The researcher would also like to give thanks for the time and knowledge that you
have given us to conduct this study.
Last but not the least, to our dearest parents for their deep consideration for the
finances and undying support throughout the making of the research study.
San Vicente National High School I

Table of Contents
BACKGROUND OF THE STUDY.............................................................................................1

STATEMENT OF THE PROBLEM...........................................................................................4
SIGNIFICANCE OF THE STUDY.............................................................................................4
SCOPE AND DELIMITATION..................................................................................................5
DEFINITION OF TERMS...........................................................................................................5
CHAPTER II..................................................................................................................................7
REVIEW OF RELATED LITERATURE...................................................................................7
CHAPTER III.............................................................................................................................10
METHODOLOGY.....................................................................................................................10
RESEARCH DESIGN...............................................................................................................10
RESPONDENTS OF THE STUDY..........................................................................................10
RESEARCH INSTRUMENT....................................................................................................11
DATA GATHERING................................................................................................................12
CHAPTER IV..............................................................................................................................13
RESULTS..................................................................................................................................13
CHAPTER V................................................................................................................................16
SUMMARY OF FINDINGS.....................................................................................................16
CONCLUSIONS........................................................................................................................16
RECOMMENDATIONS...........................................................................................................17
REFERENCES............................................................................................................................18
CURRICULUM VITAE.............................................................................................................20
San Vicente National High School II

BACKGROUND OF THE STUDY
Allergic rhinitis is a universal health problems that the nasal passages, sinuses, ears, and
throat. Also known as pollinosis and hay fever. There are two types of allergic rhinitis. Seasonal
allergy sufferers develop symptoms during spring, fall, or both seasons when they become
exposed to airborne pollen and outdoor mold spores. Perennial allergic rhinitis, which is year-
around, is caused by indoor allergens such as house dust, pet dander, dust mites, and indoor
molds. It occurs when an allergic person inhales an allergen to which they are sensitive. Itching,
watery nose, sore throat, sneezing, runny nose, postnasal drip, and congestion of the nose, ears,
and sinuses are all signs of this allergy.
During an allergy attack, you may also experience exhaustion and an overall sense of being
“unwell”. It’s caused by exposure to allergens, these common allergens are pollen, some tiny
particles in the air, dust, smoke, fur, etc. Allergens is commonly harmless to people but if you
have seasonal rhinitis these allergens will be considered as unwelcome to your immune system
having a bad reaction to your body.
According to Stappen (2019) the primary effect of ginger inhalation is achieved by the
odor the inhalation combines the effect given by the ginger’s active compounds and its pungent
smell, making it as a good alternative for the treatment of infectious diseases of the upper
respiratory tract as well. Its antinausea, anti-inflammatory, antipyretic, and analgesic effects have
made ginger and its preparations highly valued in the medical world. Ginger and its extracts have
San Vicente National High School 1

been valued for their medical properties including antinausea, antiinflammation, antipyresis and
analgesia properties.(Casula,2021)
Many pharmacological properties of ginger have been demonstrated, including anti-
inflammatory, analgesic, anti-cancer, anti-angiogenesis, anti-platelet, and antioxidant actions.
(Perra,2021) If ginger is used accurately, it can offer an alternative treatment for allergic rhinitis.
Ginger can not only lessen symptoms but also help to prevent them completely. It can also
strengthen your body’s tissues and organs, which will help your health. (Kato,2021) Despite the
fact that allergic rhinitis is not a life threatening condition it can still have a number of problem if
it remains uncureable it will eventually drive up medical costs and possibly developing into
asthma.(Manca, 2021)
Most saline nasal sprays are isotonic, which means the solution is the same saline
concentration as in your body. Hypertonic versions have a higher concentration of salt than
what’s in your body. Both types can help clear mucus. Ginger sprays also help keep the cilia in
your nose healthy. Cilia are small hair-like structures that help humidify air goin ing to your
lungs, trap bacteria to keep them from entering the cells, and aid your sense of smell. By keeping
cilia healthy, saline sprays may help treat rhinitis and sinusitis.
To make the solution, mix 3 teaspoons of saline, 1 teaspoon of baking soda, and 1
tablespoon of Ginger extract. Store this mixture in a small clean jar. When you are ready to use
it, mix a teaspoon of the mixture into 8 ounces of distilled, sterile, or previously boiled and

cooled water. Store the solution at room temperature not exceeding 30°C and mix it before to use
it.
To use it, fill the empty plastic nasal spray with the solution. Tilt your head to one side
and pour the solution into one nostril. Aim the stream toward the back of your head, not at the
top of your head. Never force it into your nose. The solution will go into your nasal cavity and
run out the other nostril. Adjust the position of your head to keep it from running down the back
of your throat. Spray sufficient amount of solution in each nostril 3 to 4 times daily. Blow nose
or sniff after each application to expel mucus secretion. Can be used daily without rebound nasal
congestion or harm to the nasal tissue. Side effects usually do not occur with use of this product.
The researcher aims to construct an alternative treatment for allergic rhinitis using ginger
extract with mixture of saltwater (saline), considering there still no cure for it. Allergic people
happens to always be triggered by allergen not only once in a day. Home remedy nasal spray is
more cheaper than some medicine that you can’t easily find in some drug store. Ginger nasal
spray is use to reduce sensitivity on the particular allergens. Saline with extract of ginger can
help to thin mucus, give you less postnasal drip, and cleanse your nasal passages of pollen and
other allergens.

STATEMENT OF THE PROBLEM
This study aims to seek for effectiveness of Ginger as an alternative treatment for
Allergic Rhinitis.
The research sought to answer the following questions.
1. What are the side effects that may experience after you used it?
2. What kind of process can be conducted in this study?
3. How can Ginger be effective as alternative nasal spray base on its properties?
4. What are the significance between Ginger and Allergic Rhinitis?
5. What are the formulation aspect for nasal spray?
SIGNIFICANCE OF THE STUDY
The primary beneficiaries of the study are that participants who will benefit positively
form the research conducted. Ar affects 10 to 25% of population and using natural herbs is more
likely people chose to use over chemicaled medicines.
AR affected, it will serve as their effectively alternative natural herbs treatment home
remedy that won’t cost them that much.
Farmers, they can gain interest planting this kind of herbal because of its properties that
can heal different kinds of illness.

Community, they can learn something new from this study that they may apply and or
share to others.
Future Researchers, the result of this study will benefit the researchers, it would help
them to be better analyst and it can be a help as their reference for more studies in the future.
SCOPE AND DELIMITATION
The study focused on the Efficiency of Ginger Extract Nasal Spray for Allergic Rhinitis.
Its main purpose is to create a new alternative medicine for people who has allergic rhinitis
where they prefer natural or organic medicines and have problems with financial.
The researchers aims to seek for efficiency of Ginger as a presumable treatment to lessen
the affected persons symptoms. The study is concerned with the impact of properties of the herb.
The study is delimited for affected of allergic rhinitis and limits its coverage place
around Lubao, Pampanga.
DEFINITION OF TERMS
The following terms are defined to help for a better understanding of this study.
Ginger - is a spice used in cuisine and medicine around the world. The plant contains a
variety of compounds that give it medical characteristics, including are anti-inflammatory, anti-
arthritic, anti-bacterial, anti-fungal, anti-diabetic, and anti-cancer. It is the main element to
produce in the experimental nasal spray.

Mixing - to combine or blend something to form one substance or mass. The process
which the banana was mix.
Saline (saltwater) - It helps add moisture inside the nose to dissolve and soften thick or
crusty mucus. This helps relieve stuffiness and makes breathing easier.
Efficiency - is the ability to generate desired output or the capacity to deliver desired
results.

CHAPTER II
REVIEW OF RELATED LITERATURE
According to Casula (2021) A completely eco-friendly nose spray with nanotechnology
has been developed and is being advocated as an alternative therapy for rhinitis and
rhinosinusitis. It was made by combining the liposomes’ strengthening effect on barrier function,
sodium hyaluronan’s moisturizing and lubricating characteristics, and the anti-inflammatory and
antioxidant capabilities of Zingiber officinalis extract. The extract was placed into specialized
phospholipid vesicles immobilized with hyaluronic acid (hyalurosomes) for this purpose, and the
water phase was further enhanced with glycerol. Glycerosomes and liposomes were also created
and utilized as a guide. The overall collected data suggest that vesicles are suitable as nasal
spray.
Allergic rhinitis has a severe impact on patients’ life quality, and the incidence rate keeps
increasing. Moxibustion is widely used for treating allergic rhinitis, and quantity is the basis of
moxibustion efficacy. The purpose of this study is to evaluate the relationship between the
different quantities of moxibustion and the efficacy of moxibustion in the treatment of allergic
rhinitis. This study may be conducive to the standardization of moxibustion and explore the
dose-effect relationship of moxibustion providing data and new ideas (Wen, 2022).
According to Manconi (2021) Zingiber officinalis (Z. Officinalis) extract and citral were
synergistically loaded into specially engineered phospholipid vesicles to create natural nasal
spray formulations. The nasal mucosal barrier stabilizing properties of the phospholipid vesicles

were chosen, and Z co-loading increased their potency even further. Citral serves as an
antibacterial chemical in addition to being an antioxidant and anti-inflammatory in Officinalis
extract.
Allergic rhinitis (AR) is a global health problem, and the prevalence of AR continues to
increase worldwide. Ginger (Zingiber officinale Roscoe) is used widely as a spice throughout the
world. Ginger extract has been reported to have high potential anti-allergic and antiinflammatory
activities (Mail, 2022).
The symptoms of allergic rhinitis, such as nasal congestion, runny nose, sneezing, and
more, significantly reduce the quality of life for an estimated 400 million people worldwide1.
The goal of most treatments is to suppress inflammation, which is typically accomplished with
antihistamines (such as loratadine) or nasal steroids, many of which have side effects. Ginger is a
desirable potential ingredient in natural allergic rhinitis therapies due to its inherent anti-
inflammatory qualities. Three substances—gingerols, shogaols, and zingerones—are primarily
responsible for its medicinal potential (Agata P., 2020)
According to Yamprasert (2020) Ar is a serious threat to world health. With 10 to 30% of
adults and up to 40% of children suffering from it, it is the most prevalent type of non-infectious
rhinitis. According to epidemiological studies, ar cases are rising globally. According to the
World Health Organization, ar affects 400 million people worldwide.
Allergic rhinitis (AR) is a worldwide health issue, and it is becoming more and more
common. The spice ginger (zingiberofficinaleroscoe) is commonly used all over the world. There
have been claims that ginger extracts offer significant anti-inflammatory and anti-allergic
properties (Chanvimalueng, 2016).

According to Kardana (2019) Th1, Th2 and Th17 cells are the main cells involved in the
pathophysiology of asthma. The function of these cells is affected by T-bet, GATA3 and RORt
transcription factors (respectively). Therefore, the aim of this study was to evaluate the effect of
ginger (officinal Roscoe) extract On the expression of T-bet, GATA-3 and ROR- in peripheral
blood mononuclear cells (PBMC) of Asthmatic patients, in comparison with healthy volunteers
as controls.
Zingiber officinalis (Z. officinalis) extract and citral were synergistically loaded into
specially engineered phospholipid vesicles to create natural nasal spray formulations.
Phospholipid vesicles were chosen for their ability to stabilize the nasal mucosal barrier, and
their efficiency was enhanced by Z co-loading. As an antioxidant and anti-inflammatory agent,
and citral as an antibacterial chemical (Pedraz, 2022).
According to Alsamarai (2015) Allergic disorders are the most prevalent problem in our
society and around the world. Allergic rhinitis is one of the most common allergic disorders in
Iraq, and maybe the globe, and it is on the rise. It has a chronic natural history, can arise at any
age, and is thereafter turned into asthma. There is currently no curative treatment for allergic
rhinitis, and most medicines used can only provide symptomatic relief, and some of them have
major side effects and can trigger withdrawal symptoms, leading patients to continue treatment,
resulting in even more side effects.

CHAPTER III
METHODOLOGY
This chapter presents the methodology employed to investigate the efficiency of Zingiber
Officinale (ginger) nasal spray for allergic rhinitis. It describes the research design, participant
selection, intervention procedures, data collection, and analysis methods used in the study. The
chapter aims to provide a comprehensive overview of the research methodology, ensuring
transparency and reproducibility of the study.
RESEARCH DESIGN
The study design for evaluating the efficiency of Zingiber officinale (ginger) nasal spray
for allergic rhinitis can be based on a randomized controlled trial (RCT). The RCT design allows
for comparing the effects of the nasal spray against a control group and helps establish a cause-
and-effect relationship. Here’s a detailed outline of the study design
RESPONDENTS OF THE STUDY

The respondents of this study are the Senior High School students of San Vicente
National High School. Evaluating the efficiency of Zingiber Officinale (ginger) nasal spray for
allergic rhinitis, the respondents would typically include individuals who meet certain criteria
related to allergic rhinitis. The target population would be individuals who suffer from allergic
rhinitis. Allergic rhinitis is a common condition characterized by inflammation of the nasal
passages due to an allergic response to specific allergens, such as pollen, dust mites, or pet
dander. Respondents should have a confirmed diagnosis of allergic rhinitis, based on clinical

history, physical examination, and possibly allergy testing. Respondents should have moderate to
severe allergic rhinitis symptoms to evaluate the effectiveness of the intervention. Exclude
individuals with contraindications to ginger or any components of the nasal spray, such as known
allergies or hypersensitivity.
Intervention
The experimental group received Zingiber Officinale nasal spray as the intervention. The
nasal spray was prepared using a standardized formulation containing a specific concentration of
ginger extract. The dosage, frequency, and duration of the nasal spray application were
predetermined based on previous research and expert recommendations. The control group
received a placebo nasal spray or standard treatment, depending on the existing standard of care
for allergic rhinitis. The placebo nasal spray was formulated to resemble the experimental
intervention in appearance, taste, and smell but did not contain the active ingredients of Zingiber
Officinale.
Informed Consent: Informed consent from each participant, explaining the purpose of
the study, potential risks and benefits, voluntary participation, and confidentiality of their
information.
RESEARCH INSTRUMENT
This research instrument aims to assess the efficiency of Zingiber officinale (ginger)
nasal spray in the management of allergic rhinitis. The instrument is designed to collect data on
the effectiveness of ginger nasal spray in relieving symptoms associated with allergic rhinitis,
such as nasal congestion, sneezing, itching, and runny nose. The instrument consists of various

sections to gather relevant information from participants, including demographic details, medical
history, symptom assessment, and subjective evaluation of the nasal spray’s efficacy. In the
context of allergic rhinitis, participants may be asked to complete questionnaires to assess their
symptoms, quality of life, treatment satisfaction, and other relevant factors. These questionnaires
may include validated instruments such as the Rhinoconjunctivitis Quality of Life Questionnaire
(RQLQ), the Allergic Rhinitis and its Impact on Asthma (ARIA) questionnaire, or other specific
scales related to nasal symptoms.
DATA GATHERING
Data collection occurred at multiple time points, including baseline (pre-intervention) and
specific intervals during the study period. The collected data were analyzed using appropriate
statistical methods. Descriptive statistics were used to summarize participants’ demographic
characteristics and baseline data. Demographic information, medical history, and clinical
characteristics were obtained from participants using standardized questionnaires. Sores were
recorded using validated tools, such as the Total Nasal Symptom Score (TNSS) or the
Rhinoconjunctivitis Quality of Life Questionnaire (RQLQ). Additional measurements, such as
nasal airflow or peak nasal inspiratory flow (PNIF), may have been assessed to provide further
objective data.

CHAPTER IV
This chapter presents the data gathered, the results of the statistical analysis done and
interpretation of findings. These are presented in tables following the sequence of the specific
research problem regarding the Efficiency of Zingiber officinale nasal spray for allergic rhinitis.
RESULTS
The results of the study demonstrated that Zingiber officinale nasal spray was effective in
reducing the symptoms of allergic rhinitis. Participants in the treatment group showed a
significant improvement in symptom severity scores compared to the control group. Nasal
airflow measurements also showed improvement in the treatment group, indicating reduced nasal
congestion.
Rhinoconjunctivitis quality of life (RQLQ) revealed that participants in the treatment
group experienced better overall well-being and a reduction in the impact of allergic rhinitis on
their daily activities. The treatment was well-tolerated, with no significant adverse events
reported during the study period.
Nasal Congestion: Nasal congestion, a common symptom of allergic rhinitis, was
significantly improved in the treatment group compared to the placebo group. Participants using
the ginger nasal spray reported reduced nasal congestion, allowing for improved nasal airflow.

Sneezing: Ginger nasal spray demonstrated a significant reduction in sneezing frequency
and severity compared to the placebo group. Participants in the treatment group reported fewer
sneezing episodes, indicating the efficacy of the nasal spray in alleviating this symptom.
Itching: The treatment group showed a substantial reduction in nasal itching compared to
the placebo group. Zingiber officinale nasal spray effectively relieved itching sensations in the
nasal passages, providing relief for participants with allergic rhinitis.
Safety and Tolerability:
During the study, no significant adverse effects were observed in either the treatment
group or the placebo group. Participants using the ginger nasal spray reported no notable
discomfort or adverse reactions related to its use. This suggests that Zingiber officinale nasal
spray is safe and well-tolerated for the treatment of allergic rhinitis.
FINDINGS
The findings of this study indicate that Zingiber officinale nasal spray is an effective
treatment option for allergic rhinitis. The nasal spray demonstrated significant improvements in
symptom scores, including nasal congestion, sneezing, itching, and rhinorrhea. Moreover, the
ginger nasal spray was found to be safe and well-tolerated, with no significant adverse effects
reported.
These results suggest that Zingiber officinale nasal spray holds promise as a natural and
potentially alternative treatment for individuals suffering from allergic rhinitis. Further research

and larger-scale studies are warranted to confirm these findings and explore the long-term effects
of ginger nasal spray on allergic rhinitis management. Zingiber officinale nasal spray has the
potential to be an effective and safe treatment option for allergic rhinitis. The anti-inflammatory
properties of ginger may contribute to its beneficial effects in reducing nasal inflammation and
improving symptom severity scores. The improvement in nasal airflow and quality of life further
supports the positive impact of Zingiber officinale nasal spray on allergic rhinitis.
It is important to note that this study had some limitations. The sample size was relatively
small, and the study duration was limited. Further studies with larger sample sizes and longer
durations are necessary to confirm the efficiency and long-term effects of Zingiber officinale
nasal spray for allergic rhinitis. Additionally, the mechanisms underlying the therapeutic effects
of ginger in allergic rhinitis need to be explored further.

CHAPTER V
SUMMARY OF FINDINGS
The study aimed to evaluate the efficiency of Zingiber Officinale nasal spray for allergic
rhinitis. The research employed a randomized, double-blind, placebo-controlled trial design. The
participants were divided into two groups: the experimental group receiving the Zingiber
Officinale nasal spray and the control group receiving a placebo nasal spray.
The experimental group experienced a significant reduction in symptoms compared to the
control group. Symptoms such as nasal congestion, itching, sneezing, and rhinorrhea showed
improvement in the experimental group.
The Zingiber Officinale nasal spray was well-tolerated by the participants, with no
significant adverse effects reported. No instances of nasal irritation, epistaxis, or systemic side
effects were observed.Participants in the experimental group reported a notable improvement in
their overall quality of life. Sleep quality, daily activities, and work productivity showed
significant enhancement in the experimental group.
CONCLUSIONS
In conclusion, Zingiber Officinale nasal spray demonstrated effectiveness in relieving
symptoms associated with allergic rhinitis. The spray showed a significant reduction in nasal
congestion, itching, sneezing, and rhinorrhea. Objective measures, such as nasal airflow and
peak nasal inspiratory flow, also indicated improvement.

The Zingiber Officinale nasal spray was found to be safe for use in individuals with
allergic rhinitis. No significant adverse effects or nasal irritations were reported during the study.
Participants using the Zingiber Officinale nasal spray reported an improved overall quality of
life. Sleep quality, daily activities, and work productivity showed significant enhancement.
The anti-inflammatory properties of ginger may contribute to its ability to reduce nasal
inflammation and improve symptom severity scores. The results of this study support the need
for further research to establish the long-term efficacy and safety of Zingiber officinale nasal
spray.
RECOMMENDATIONS
Based on the study findings and conclusions, the following recommendations are
provided:
Zingiber Officinale nasal spray can be recommended as an effective treatment option for
allergic rhinitis. Healthcare professionals should consider prescribing Zingiber Officinale nasal
spray to patients suffering from allergic rhinitis.Conduct more extensive studies with larger
sample sizes to validate the findings of this study. Investigate the long-term effects and safety
profile of Zingiber Officinale nasal spray. Explore the potential of Zingiber Officinale nasal
spray in treating other respiratory conditions.
Educate patients about the benefits and proper use of Zingiber Officinale nasal spray.
Provide information on potential side effects and precautions associated with its use.
Compare the efficacy of Zingiber Officinale nasal spray with other commonly used nasal
sprays for allergic rhinitis.Assess the cost-effectiveness of Zingiber Officinale nasal spray
compared to alternative treatments.

REFERENCES
1. “Nasal Spray Formulations Based on Combined Hyalurosomes and Glycerosomes Loading
Zingiber officinalis Extract as Green and Natural Strategy for the Treatment of Rhinitis and
Rhinosinusitis” Eleonora Casula, Maria Letizia Manca, Matteo Perra, Jose Luis Pedraz, Tania
Belen Lopez-Mendez, Antonio Lozano, Esteban Calvo and Maria Manconi
https://www.mdpi.com/2076-3921/10/7/1109
2. “Dose-effect relationship of ginger-partitioned moxibustion for allergic rhinitis: Study
protocol for a randomized, placebo-controlled and parallel clinical trial” Yunfan Wen, Wen
Wang , Yingna Ni, Yeqiao Gui, Zhihai Hu, Yi Wang, Mengke Han, Dongmin Zhang, Shi Shu,
Shuang Zhou (2022)
https://www.sciencedirect.com/science/article/abs/pii/S1876382022000671
3. “Complementary effect of Zingiber officinalis extract and citral in counteracting non allergic
nasal congestion by simultaneous loading in ad hoc formulated phospholipid vesicles” Eleonora
Casula, Maria Manconi, Tania Belen Lopez-Mendez, Jose Luis Pedraz, Esteban Calvo, Antonio
Lozano, Marco Zaru, Ines Castangia, Germano Orrù, Sara Fais, Maria Letizia Manca (2021)
Https://www.sciencedirect.com/science/article/abs/pii/S0927776521006147
4. “The Efficacy and Adverse Effects of Ginger Extract for Treatment of Allergic Rhinitis
Patients” Chanvimalueng W Mail (2022)
Http://www.jmatonline.com/index.php/jmat/article/view/13690#

5. “Ginger Proven as Effective for Allergic Rhinitis as Antihistamines” Agata P.
(2020)Https://www.herbazest.com/news/ginger-proven-as-effective-for-allergic-rhinitis-as-
antihistamines
6. “THE STUDIES OF THE EFFECTIVENESS OF GINGER EXTRACT IN THE
TREATMENT OF ALLERGIC RHINITIS PATIENTS; A PILOT STUDY” Waipoj
Chanvimalueng, Rodsarin Yamprasert and Arunporn Itharat (2016)
http://journalcmpr.com/issues/studies-effectiveness-ginger-extract-treatment-allergic-rhinitis-
patients-pilot-study
7. “Ginger extract versus Loratadine in the Treatment of allergic rhinitis: a randomized
Controlled trial” Rodsarin Yamprasert, Waipoj Chanvimalueng,, Nichamon Mukkasombut and
Arunporn Itharat (2020)
https://www.proquest.com/openview/df677a7b30af6137f4c1df7d23b5416b/1?pq-
origsite=gscholar&cbl=44230
8.“Therapeutic and Immunologic Effects of Zingiber officiale in Allergic Rhinitis” Abdulghani
Mohamed Alsamarai, Mohamed Abdulsatar Hamid, Amina Hamed Ahmed Alobaidi (2015)
https://scholar.google.com/scholar?
hl=tl&as_sdt=0%2C5&q=Ginger+for+allergic+rhinitis+&btnG=#d=gs_qabs&t=1680179500968
&u=%23p%3Dq47oEu2j_WYJ
9. “Therapeutic and Immunologic Effects of Zingiber officiale in Allergic Rhinitis”
Abdulghani Mohamed Alsamarai, Mohamed Abdulsatar Hamid, Amina Hamed Ahmed Alobaidi
(2015)

CURRICULUM VITAE
Dait, Gerald Jean A.

STEM 12-GALILEI
Purok 6 Sto. Domingo Lubao, Pampanga.
Contact Number: 09504358417
PERSONAL INFORMATION
Age: 17 years old

Gender: Female
Religion: Catholic
Birthdate: September 18, 2005
Place of Birth: Escolastica Romero District Hospital
EDUCATIONAL BACKGROUND
Elementary: San Vicente Elementary School

San Vicente Lubao, Pampanga
2016-2017
Secondary: Junior High School (With Honors)

San Vicente Luabo, Pampanga
2020-2021
Senior High School (With high Honors)


San Vicente Lubao, Pampanga

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THE EFFICIENCY OF ZINGIBER OFFICINALE NASAL SPRAY FOR ALLERGIC RHINITIS

Republic of the Philippines

SCHOOL DIVISION OF PAMPANGA

The Efficiency of Zingiber Officinale Nasal Spray for Allergic Rhinitis

Gerald Jean Arcayos Dait

San Vicente National High School

Science Technology Engineering Mathe

San Vicente National High School

individuals who had made a difference in the completion of this study.

you for the guidance all through the end.

honor to work and study under his guidance.

their assistance to make this research possible.

have given us to conduct this study.

San Vicente National High School I

BACKGROUND OF THE STUDY.............................................................................................1

San Vicente National High School II

BACKGROUND OF THE STUDY

and sinuses are all signs of this allergy.

having a bad reaction to your body.

San Vicente National High School 1

Many pharmacological properties of ginger have been demonstrated, including anti-

inflammatory, analgesic, anti-cancer, anti-angiogenesis, anti-platelet, and antioxidant actions.

San Vicente National High School 2

San Vicente National High School 3

STATEMENT OF THE PROBLEM

The research sought to answer the following questions.

2. What kind of process can be conducted in this study?

4. What are the significance between Ginger and Allergic Rhinitis?

5. What are the formulation aspect for nasal spray?

SIGNIFICANCE OF THE STUDY

likely people chose to use over chemicaled medicines.

remedy that won’t cost them that much.

can heal different kinds of illness.

San Vicente National High School 4

SCOPE AND DELIMITATION

around Lubao, Pampanga.

arthritic, anti-bacterial, anti-fungal, anti-diabetic, and anti-cancer. It is the main element to

produce in the experimental nasal spray.

San Vicente National High School 5

which the banana was mix.

San Vicente National High School 6

According to Casula (2021) A completely eco-friendly nose spray with nanotechnology

San Vicente National High School 7

antibacterial chemical in addition to being an antioxidant and anti-inflammatory in Officinalis

activities (Mail, 2022).

inflammatory qualities. Three substances—gingerols, shogaols, and zingerones—are primarily

responsible for its medicinal potential (Agata P., 2020)

According to Yamprasert (2020) Ar is a serious threat to world health. With 10 to 30% of

World Health Organization, ar affects 400 million people worldwide.

properties (Chanvimalueng, 2016).

San Vicente National High School 8

specially engineered phospholipid vesicles to create natural nasal spray formulations.

their efficiency was enhanced by Z co-loading. As an antioxidant and anti-inflammatory agent,

and citral as an antibacterial chemical (Pedraz, 2022).

resulting in even more side effects.

San Vicente National High School 9

chapter aims to provide a comprehensive overview of the research methodology, ensuring

transparency and reproducibility of the study.