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Debierizqoh, Eka Suryani, ALM
Debierizqoh, Eka Suryani, ALM
ABSTRACT
Leukocytes are blood cells that play a role in the immune mechanism. Leukocytes are
classified based on the presence or absence of granules in the cytoplasm of leukocytes,
which consist of granulocytes and agranulocytes. The normal leukocyte count is 3200-
10000/mm3 of blood. If the leukocytes are above the normal limit, it is called
leukocytosis. Leukocytosis can be pathological or physiological. Physiological
leukocytosis that occurs during pregnancy is common due to two reasons, namely a
physiological stress and an increased inflammatory response. Physiological stress arises
as a response to changes that occur in the body of pregnant women, including the
workload of the heart, digestive system, metabolism, thereby stimulating the production
of white blood cells to increase immunity. The inflammatory response is a form of the
body's selective immune tolerance, immunosuppression and immunomodulation of the
fetus. The purpose of this study was to determine the relationship between gestational age
and leukocyte count in pregnant women at the Slahung Health Center, Ponorogo
Regency, which was conducted in July 2021.
This study uses an analytical observational analytic method with a cross sectional
approach. This research was conducted by examining gestational age and leukocyte
count in pregnant women with a total sample of 30 samples and using a total sampling
technique. Examination of the number of leukocytes using the Hematology Analyzer URIT
3000 Plus. The results based on the average number of leukocytes from this study in the
first trimester were 3.20 x103/mm3, in the second trimester 8.42 x103/mm3, and in the
third trimester 12.56 x103/mm3. The results of test using the Kruskal-Walis obtained a
significance value of 0.000 < 0.05. The results of this study can be concluded that there is
a relationship between gestational age and the number of leukocytes in pregnant women.
Hasil Penelitian
Tabel 2. Data Deskriptif Jumlah
Penelitian Hubungan Antara Usia
Leukosit Pada Ibu Hamil
Kehamilan Dengan Jumlah Leukosit
Di Puskesmas Slahung telah N Mean SD Min Max
dilakukan di Puskesmas Slahung
Kabupaten Ponorogo dari tanggal
trimester 1 6 6,12 0,93 5,20 7,90
12 Juli 2021
trimester 2 11 8,40 2,26 6,10
sampai dengan 24 Juli 2021. Dari 12,30
populasi ibu hamil yang periksa trimester 3 13 10,42 2,03 8,50 15,60
darah lengkap didapatkan sampel Total 30 8,82 2,52 5,20 15,60
sebanyak 30 menggunakan teknik
total sampling dengan hasil sebagai
Dari tabel 2 karakteristik subyek
berikut:
penelitian didapatkan dari 30
responden memiliki rerata jumlah
Tabel 1. Distribusi frekuensi
berdasarkan usia kehamilan leukosit pada trimester satu 6,12
x103/mm3, dengan simpangan baku
0,93. Pada trimester dua
Usia Jumlah Prosentase 8,40x103/mm3, simpangan baku
Kehamilan (30) (%) 2,26. Pada trimester tiga
Trimester 1 6 20,0 10,42x103/mm3, simpangan baku
Trimester 2 11 36,7
Trimester 3 13 43,3
2,03. Berdasarkan hasil tersebut
Total 30 100 menunjukkan bahwa mean jumlah
leukosit lebih besar dari simpangan
Tabel 1 distribusi frekuensi baku sehingga dapat diartikan
berdasarkan usia kehamilan bahwa data jika nilai standar
didapatkan 6 (20%) pada trimester deviasinya lebih kecil dari nilai mean
satu, 11 (36,7%) pada trimester dua, maka menunjukkan bahwa nilai
dan 13 (43,3 %) pada trimester tiga. mean dapat digunakan sebagai
representasidari keseluruhan data.