Grading System: Lecture 60% Quizzes 40 points Exams 60 points Bonus 10 points Laboratory 40% Today's mammalian species have relatively large and complex brains and complex body systems. Therefore, development of the offspring takes a fairly long period of time. Part of this development occurs intrauterine during gestation. However, in mammals much of this development continues after birth and is extra-uterine development. In that sense, the newborn mammal is still very much dependent on the mother for provision of a nutrient supply that matches its digestive capabilities. This nutrient supply is milk. Milk is of paramount importance to: survival, proper development, and vigorous growth of the neonate. Milk is the only supply of the water, organic nutrients, and minerals to which the neonate has access. Milk supplies everything to the neonate except air! Milk has a high caloric value and generally is balanced for the nutrient needs of the rapidly developing young of that species. Colostrum (the first milk taken from the mammary gland after parturition) and mature milk also contain non-nutrient substances (such as antibodies and bioactive factors) that may be important for: growth, development, and survival of the neonate. Cow milk provides a plentiful, nutritious, and well characterized source of nutrient components for milk replacers, infant formulas, and other food sources for the neonate. Non-milk components can also be used to supply the neonate with nutrients if mother's milk is not available or if cow milk- based formulas are not appropriate for use for the neonate. Lactation is an integral component of the highly successful reproductive strategy of mammalian species. Mammals reproduce multiple times in their lives. That means that the requirement to provide nutrients to the newly hatched or newly born offspring occurs intermittently. A mammary gland that lactates continually is not an energetically favorable concept, whereas a mammary gland that develops and functions in concert with the reproductive cycle of the animal makes much more sense. In fact, development of the mammary gland is closely integrated with the reproductive cycle of the species. Lactation and reproductive processes are intimately intertwined in mammals. Some of the factors that are involved in control of pregnancy are the same factors that are involved in regulating mammary development during pregnancy. Reproduction and lactation are part of the same overall process. The ultimate objective of reproduction is to produce the next generation of reproductively viable offspring. The female mammal (mother) makes a large metabolic investment in the early development of the offspring. This investment continues until the offspring is metabolically independent from the mother. Lactation is a continuation of the metabolic investment of the mother and is the most energetically demanding part of reproduction. In the absence of successful lactation (or in the absence of human intervention) the neonate will not survive after birth even with optimal success of all the complex processes involved in estrous cycles, conception, pregnancy, fetal development, and parturition. The result will be a failure of the reproductive process. Milk is the physiological secretion of the mammary gland of mammals to provide nourishment to the young sometimes called nature’s most perfect food obtained from cows, goats, sheep, buffaloes camels and even mares Physico-chemical Properties: It is a complex mixture of a wide range of compounds important to the neonate. The gross properties of milk include:
an emulsion of fat globules, and
a suspension of casein micelles (casein, calcium, phosphorous), all of which are suspended in an aqueous phase, that contains solubilized lactose, whey proteins, and some minerals. Leukocytes in milk are part of the suspended phase. Some other physicochemical characteristics of cow milk: pH of normal milk is about 6.6 - 6.9 (milk of carnivores is about 6.2; human milk is about 7.0; cow colostrum as low as 6.0; milk from cows with mastitis as high as 7.5) osmolality is about 0.3 M (osmotic pressure ~ 700 kPa) ionic strength is about 0.08 molar water activity is about 0.993 Gross Composition of Whole Milk, % Water 87.2 Fat 3.7 Protein 3.5 Carbohydrates 4.9 Minerals 0.7 1. Fresh Milk -milk straight from the udder of the cow, pasteurized and homogenized -has a shelf life of 7-10 days under refrigeration 2. Cream - milk fat removed from the milk - manufactured as butter or sold as buttermilk (by-product from butter manufacture) for feed or processed into powder 3. Skimmed milk milk after removing the cream processed into skim milk or casein powder or casein whey 4. Cheese
curdled milk after coagulation with rennet
and the whey removed 5. Evaporated milk could be made into sweetened or unsweetened condensed milk 6. Whole Milk Powder
spray dried milk
milk is turned into a mist for easier drying 1. Walter L. Hurley. The Lactation Biology website. University of Illinois, Urbana, IL. USA 2. Lactation and the Mammary Gland. 2002. R. Michael Akers. Blackwell Publishing, Ames, Iowa, USA