BIOCHEMISTRY COMPILED QUIZZES

MEMBRANE STRUCTURE AND FUNCTION

1. Which of the following types of molecules are the major structural components of the
cell membrane?

a. phospholipids and cellulose

b. nucleic acids and proteins
c. phospholipids and proteins
d. proteins and cellulose

2. When biological membranes are frozen and then fractured, they tend to break along the
middle of the bilayer. The best explanation for this is that

A. the hydrophobic interactions that hold the membrane together are weakest at this
point.
B. hydrophilic interactions between the opposite membrane surfaces are destroyed on
freezing.
C. water that is present in the middle of the bilayer freezes and is easily fractured
D. the integral membrane proteins are not strong enough to hold the bilayer together.

3. The presence of cholesterol in the plasma membranes of some animals

A. enables the membrane to stay fluid more easily when cell temperature drops.
B. enables the animal to remove hydrogen atoms from saturated phospholipids.
C. enables the animal to add hydrogen atoms to unsaturated phospholipids.
D. makes the membrane less flexible, allowing it to sustain greater pressure from within
the cell.

4. According to the fluid mosaic model of cell membranes, which of the following is a true
statement about membrane phospholipids?

A. They can move laterally along the plane of the membrane.

B. They frequently flip-flop from one side of the membrane to the other.
C. They occur in an uninterrupted bilayer, with membrane proteins restricted to the
surface of the membrane
D. They are free to depart from the membrane and dissolve in the surrounding solution.

5. In order for a protein to be an integral membrane protein it would have to be which of

the following?

A. hydrophilic
B. hydrophobic
C. amphipathic
D. completely covered with phospholipids
BIOCHEMISTRY COMPILED QUIZZES

GLYCOPROTEINS

1. Enzyme deficiency in I cell disease

A. GlcNac Phosphotransferase
B. Mannose Phosphotransferase
C. Phosphodiesterase
D. Mannose 6 phosphotransferase

2. A test done to diagnose Paroxysmal Nocturnal Hemoglobinuria

A. Hams test
B. Plasma pH test
C. Urinalysis
D. All of the above

3. Which of the following amino acid can have O glycosidic linkage in oligosaccharide
molecule?

A. Asparagine
B. Glutamine
C. Serine
D. Cysteine

4. It is the commonest way in which various proteins are anchored to cell membranes

A. O-linked glycoprotein
B. N-linked glycoproteins
C. GPI linked
D. None of the above

5. Immunoglobulins are

A. Proteins
B. Glycoproteins
C. Proteoglycans
D. Glycoside
BIOCHEMISTRY COMPILED QUIZZES

EXTRACELLULAR MATRIX

1. also called hereditary nephritis affecting type IV collagen

A. Ehlers Danlos Syndrome
B. Alport Syndrome
C. Menkes Disease
D. Williams Beuren Syndrome

2. Characterized by increased bone density*

A. Osteoporosis
B. Osteopetrosis
C. Osteopenia
D. Osteoplasia

3. It is involved in the attachment of type II collagen to Chondrocytes*

A. Chondronectin
B. Aggrecan
C. Fibrillin
D. Fibronectin

4. Proteoglycan originally isolated from the cornea

A. Keratan Sulfate I
B. Keratan Sulfate II
C. Chondroitin 4-Sulfate
D. Chondroitin 6-sulfate

5. 90-98% of collagen type found in cartilage*

A. Collagen type I
B. Collagen type II
C. Collagen type III
D. Collagen type IV
BIOCHEMISTRY COMPILED QUIZZES

PLASMA PROTEINS

1. Prealbumin found in lower level in :

A. Liver disease.

B. Nephrotic syndrome.

C. Malnutrition.

D. All.

2. 80 % of plasma oncotic pressure is maintained by albumin.

A. True
B. False

3. Hypoalbuminemia could be carried by:-

A. Decrease in synthesis in liver.

B. Loss of albumin.

C. Severe burns.

D. All of them.

4. Clinical consequences of alpha (a)-antitrypsin deficiency

A. Jaundice.

B. Pulmonary emphysema.

C. Liver cirrhosis.

D. All above.

5. Ceruloplasmin important in :

A. Iron absorption from intestine.

B. Transplant.

C. None of them.

D. Both of them.
BIOCHEMISTRY COMPILED QUIZZES

Hemostasis and Thrombosis Quiz