COLLAGEN ALPHA-KERATIN BETA-KERATIN

Structure A helix of three chains Occurs as an alpha Occurs as a beta helix

attached by covalent helix sheet to which N sheet to which N and
bonds and C terminal groups C terminal groups
attach and many attach and many
disulfide bonds are disulfide bonds are
present present
Abundant amino acid Glycine, Cysteine Cysteine
hydroxyproline,
proline
Where is it found Found in hair, horns, Found in reptile skin
nails and the skin and birds
Commercial use Used when surgical Often used in making Often used in making
reconstruction need cosmetics and as an cosmetics and as an
to be done addictive in making addictive in making
ceramics ceramics
Formation Is formed inside living Is formed inside living And is also formed
cells called fibroblasts skin cells called inside living skin cells
keratinocytes called keratinocytes
Diseases Ehlers-danlos Epidermolysis bullosa Epidermolysis bullosa
syndrome simplex and simplex and
epidermolytic epidermolytic
hyperkeratosis hyperkeratosis