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Textbook of Pharmaceutical Inorganic Chemistry

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Hemraj Sharma
Shree Medical and Technical College
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 Textbook of
PHARMACEUTICAL
INORGANIC CHEMISTRY

Author
Hemraj Sharma

Publisher and Distributor

Samiksha Publication (P.) Ltd.
Textbook of

PHARMACEUTICAL
INORGANIC CHEMISTRY
Publisher & Distributor:
Samiksha Publication Pvt. Ltd.
Corporate Office
Rautahadevi Marga, Ghattekulo, Kathmandu- 29
Phone No.: 01-4538282, 4535257
www. samikshapublication.com.np
Email: info@samikshapublication.com.np

Distribution & Sales

Samiksha Books Center
Adwaitmarga (Near old Buspark)
Bagbazar, Kathmandu
Phone No.: 01-4230184, 01-4244456

Distribution & Sales

Samiksha Books Pvt. Ltd.
New Plaza, Putalisadak, Kathmandu
Phone No.: 01-4540611
Edition : First, 2022
Author : Hemraj Sharma
© : Author
ISBN : 978-9937-759-35-9
Computer : Puja Sharma
Price : Rs. 695.00
Dedicated to:
My Father
 Preface

This book is an introduction to the Inorganic Pharmaceutical substances and

their applications in ield of Pharmacy and Chemistry. Each chapter is largely
self-contained, started with a fundamental knowledge of each inorganic drug
and eventually deals with all its speci ications like method of preparations,
identi ication tests, impurity pro iling and testing and assay.
All the chapters in this book are in accordance with the syllabus of various
Universities of Nepal, like Purbanchal University, Tribhuvan University,
Kathmandu University and Pokhara University.
To make easy and effective understanding for students, this book also consists
list of Practical associated with the theory, which will de initely help the
students to learn. Point wise and tabular presentation of the topic is the main
features of this book. Hope this book will help B. Pharm & D. Pharm students
as well as chemistry students to understand Inorganic Pharmaceutical
substances, impurities and their limit test procedures in easy way.
I express my gratitude to my colleagues, friends and family who, by their
encouragement and advice helped me to write this book.
I am grateful to Mr. Mohan Acharya, CEO, Samiksha Publication, Kathmandu
for the interest for the preparation of the book.
Finally I thank my mother Punadevi Sharma and wife Roshani Bhattarai who
inspired me during the preparation of the book. I will welcome any criticism of
the subject matter and style for further improvement of this new enterprise.

Hemraj Sharma
 Table of Contents

Chapter 1 : Introduction to Inorganic Pharmaceutical Chemistry ....1-4

 Impurity in Pharmaceu cal Substances .............................................. 3
 Test for Purity ..................................................................................... 4

Chapter 2 : Limit Test ...................................................................5-24

 Chemical analysis............................................................................... 17
 Error ......................................................................................... 20

Chapter 3 : Acids, Bases and Buffer ............................................25-62

 Introduc on to Acid & Base .............................................................. 26
 Official Bases ..................................................................................... 34
 Acidosis and Alkalosis ........................................................................ 40
 Buffer Solu on .................................................................................. 42
 Water & Monograph Study................................................................ 53

Chapter 4 : Gastrointestinal Agents ............................................63-94

 Acidifying agents (Acidifiers) .............................................................. 65
 Antacids 66
 Protec ve And Adsorbent.................................................................. 82
 Cathar cs (Purga ves) ....................................................................... 86

Chapter 5 : Major Intra and Extracelluar Electrolytes............... 95-132

 Role of Physiological Ions................................................................... 99
 Electrolytes used in acid-base Therapy ............................................ 102
 Official Electrolytes Prepara ons ..................................................... 110

Chapter 6 : Essential Trace Elements ...................................... 133-148

 Iron ....................................................................................... 135
 Mineral Supplements ...................................................................... 142

Chapter 7 : Tropical Agents .................................................... 149-184

 Protec ve agents ............................................................................. 150
 Local An -infec ve (an -microbial agents)...................................... 158

Chapter 8 : Gases and Vapour ................................................ 185-196

 Oxygen ....................................................................................... 187
 Carbon Dioxide ................................................................................ 189
  Nitrous Oxide ................................................................................... 191
 Oxygen Therapy ............................................................................... 192

Chapter 9 : Dental Products ........................................................ 197-212

 An caries agent .............................................................................. 205
 Den frices ....................................................................................... 207
 Desensi zing agents ........................................................................ 208

Chapter 10 : Complexing and Chelating Agents............................. 213-228

 Introducon to Complexing and Chela ng Agents .......................... 214
 Heavy metal poisoning ................................................................... 215
 An dotes (Heavy metal Antagonist) ................................................ 217

Chapter 11 : Miscellaneous Medical Agents ................................. 229-244

 Sclerosing agents ............................................................................. 230
 Expectorants .................................................................................... 231
 Eme cs ....................................................................................... 234
 Seda ves ....................................................................................... 235
 An oxidants and Preserva ves ........................................................ 235
 Filter aids ....................................................................................... 240
 Excipients ....................................................................................... 241
 Colouring Agents ............................................................................. 242
 Adsorbents and Absorbents ............................................................ 242

Chapter 12 : Inorganic Radiopharmaceuticals ............................... 245-274

 Introduc on to Radiopharmaceu cals ............................................ 246
 Radioac ve Agents .......................................................................... 263
 Applica ons of Radio Pharmaceu cals ............................................ 270

Chapter 13 : Organic Chemistry .................................................... 275-356

 Introduc on to Nomenclature of Organic Compounds ................... 276
 Heterocyclic compounds ................................................................. 304

Chapter 14 : IPC Practical Book .................................................... 357-428

Index ............................................................................ 429-432

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