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User Manual For XL-180 - v2022.C01
User Manual For XL-180 - v2022.C01
for
XL-180
Preface
This manual gives you detailed instructions on how to setup the analyzer for the first time, install
MultiXL software on the analyzer PC and schedule a basic run for a sample test.
It also contains a detailed description of unpacking the analyzer, accessories checklist, and
installation of components of the analyzer.
The screenshot and hardware images in this publication have been added exclusively for
illustration purposes.
Operation and maintenance actions are described in the User Manual and Online Help.
User must read this manual before installing the analyzer and its software application.
Legal Information
All rights are reserved by manufacturer of this product.
Manufacturer is the copyright owner of this document.
The contents of this document are subject to change without prior notice and without legal
obligation.
This document and the information herein are provided for the sole use of the intended recipient(s)
and for information purposes only.
This document contains contents which are the confidential and proprietary information of the
manufacturer.
This document can not be modified, reproduced, translated, or transmitted in any form or by any
means for any purpose, without prior written permission from the manufacturer.
No part of this document can be copied or reprinted, in whole or in part, without prior written
permission from the manufacturer.
Disclaimer
While every effort has been made to ensure the accuracy and completeness of the provided
information, it cannot be guaranteed that the manual is free of errors. Therefore, the manufacturer
shall not be held responsible and disclaims all liability for any loss or damage resulting from errors
or omissions in this document.
The content and specifications of the manual are subject to change without prior notice.
Any misusage or unspecified modifications to the instrument will void the warranty and may result
in injuries. All operators are urged to carefully read and follow the safety instructions and
precautions which are intended to protect them against injuries and the instrument from damage.
4 Document Conventions
Consult instructions Indicates the need for the user to consult the
for use instructions for use.
Date of manufacture Indicates the date when the medical device IVD
was manufactured.
Document Conventions 5
Before reading the manual, please get familiarized with the following icons used in this manual.
Icons Warnings
Bio-hazard
Electric shock
High temperature
Injury
Table of Contents
Foreword 11
XL-180
8 Contents
.........................................................................................................................................................
Receiving Instructions 2-7
Warranty
.........................................................................................................................................................
Information 2-7
Unpacking ..........................................................................................................................................................
the analyzer 2-8
Accessories..........................................................................................................................................................
Checklist 2-8
Installing
..........................................................................................................................................................
the com ponents of analyzer 2-10
Connecting communication cable betw een data station computer and
......................................................................................................................................................... 2-10
analyzer
Installing
.........................................................................................................................................................
the Sample and Reagent Tray (SRGT) 2-11
Installing
.........................................................................................................................................................
the Rotor Tray 2-11
Installing
.........................................................................................................................................................
DI Water and Waste Can 2-12
Printer
.........................................................................................................................................................
Installation (DeskJet / Laser) 2-13
Test.........................................................................................................................................................
Loader Device Connecting to USB on analyzer PC 2-13
XL-180
Contents 9
XL-180
10 Contents
Add.........................................................................................................................................................
Sample and Reagent 6-98
ISE.........................................................................................................................................................
Pack 6-100
Refresh
.........................................................................................................................................................
Position 6-101
Scan
.........................................................................................................................................................
Pack 6-102
Search.......................................................................................................................................................... 6-104
Patient/Samples
......................................................................................................................................................... 6-105
Patient
.........................................................................................................................................................
Results 6-106
Calib/Control
.........................................................................................................................................................
Results 6-107
Consumables
......................................................................................................................................................... 6-108
Tests
......................................................................................................................................................... 6-109
Reports .......................................................................................................................................................... 6-110
Patient
.........................................................................................................................................................
Reports 6-111
Result
.........................................................................................................................................................
Reprint 6-117
Test
.........................................................................................................................................................
Statistics 6-119
Calibration
.........................................................................................................................................................
Trace 6-121
Calibration
.........................................................................................................................................................
Monitor 6-122
Error
.........................................................................................................................................................
Log 6-123
Reaction
.........................................................................................................................................................
Curve 6-125
Other
......................................................................................................................................................... 6-127
Master.......................................................................................................................................................... 6-132
Area
......................................................................................................................................................... 6-133
Doctor
......................................................................................................................................................... 6-133
Analyst
......................................................................................................................................................... 6-134
Laboratory
......................................................................................................................................................... 6-135
Mfg......................................................................................................................................................... 6-136
Reference
.........................................................................................................................................................
Range 6-137
Unit
......................................................................................................................................................... 6-138
Calculation
.........................................................................................................................................................
Formula 6-139
Instrument
......................................................................................................................................................... 6-140
Unit
.........................................................................................................................................................
Conversion 6-141
Utility .......................................................................................................................................................... 6-145
Reagent
.........................................................................................................................................................
Position 6-146
Transfer
.........................................................................................................................................................
To Tube 6-147
Backup
......................................................................................................................................................... 6-150
Backup Operations
......................................................................................................................................... 6-150
Copy Data .........................................................................................................................................
to External Storage Device 6-151
System Backup .........................................................................................................................................
Restore 6-152
Offline
.........................................................................................................................................................
Results 6-153
Recalculate
......................................................................................................................................................... 6-155
Service..........................................................................................................................................................
Check 6-156
Maintenance
.......................................................................................................................................................... 6-163
Maintenance
......................................................................................................................................................... 6-164
Span (Auto .........................................................................................................................................
and Manual) 6-164
Wash ......................................................................................................................................... 6-165
Dilution Calibration
.........................................................................................................................................
Factor 6-167
Dead Volume .........................................................................................................................................
Calibration 6-167
ISE Unit ......................................................................................................................................... 6-169
Auto Maintenance
......................................................................................................................................... 6-173
Cell.........................................................................................................................................................
Blank 6-175
Maintenance
.........................................................................................................................................................
Log 6-177
Settings.......................................................................................................................................................... 6-178
System
.........................................................................................................................................................
Parameters 6-179
Carryover
.........................................................................................................................................................
Pairs 6-182
Test
.........................................................................................................................................................
Sequence 6-184
Test Display .........................................................................................................................................
Sequence 6-185
Test Process .........................................................................................................................................
Sequence 6-186
Print Sequence.........................................................................................................................................
For Patient Reports 6-187
Profile Sequence
.........................................................................................................................................
For Patient Reports 6-187
XL-180
Contents 11
.........................................................................................................................................................
Re-run Flags 6-187
User
.........................................................................................................................................................
Rights 6-188
Host
.........................................................................................................................................................
Settings 6-189
Send Patient .........................................................................................................................................
Results to Host 6-191
Send Control .........................................................................................................................................
Results to Host 6-191
Schedule.........................................................................................................................................
Test Again 6-191
Send Sample .........................................................................................................................................
Position 6-191
Query Sample .........................................................................................................................................
at a Time 6-191
Checksum ......................................................................................................................................... 6-192
Check Connection
......................................................................................................................................... 6-192
Clear Result .........................................................................................................................................
Queue 6-192
Shut Dow
..........................................................................................................................................................
n 6-192
Shutdow
.........................................................................................................................................................
n MultiXL 6-192
Perform
.........................................................................................................................................................
Maintenance before MultiXL Shutdow n 6-192
Master..........................................................................................................................................................
Calibration 6-193
Archive
.......................................................................................................................................................... 6-195
Archiving
.........................................................................................................................................................
Data 6-196
View
.........................................................................................................................................................
ing Archived Data 6-197
Observations
......................................................................................................................................................... 6-199
XL-180
12 Contents
.......................................................................................................................................................... 9-11
Add doctor
Add analyst
.......................................................................................................................................................... 9-12
Add laboratory
.......................................................................................................................................................... 9-12
Add m anufacturer
.......................................................................................................................................................... 9-13
Add reference
..........................................................................................................................................................
range 9-14
Add unit.......................................................................................................................................................... 9-15
Add calculation
..........................................................................................................................................................
form ula 9-15
Add instrum
..........................................................................................................................................................
ent 9-16
7 Archive
................................................................................................................................
Data 9-17
Archiving
..........................................................................................................................................................
Data 9-18
View ing..........................................................................................................................................................
Archived Data 9-19
Observations
.......................................................................................................................................................... 9-21
8 Create
................................................................................................................................
profile 9-22
Add profile
.......................................................................................................................................................... 9-22
Delete profile
.......................................................................................................................................................... 9-22
XL-180
Foreword 13
Foreword
This manual is organized in a progressive sequence for easy study and reference. It is an
instructional aide to provide a reference for easy operation and general maintenance of this
analyzer. It contains detailed description of the analyzer features and specifications. The analyzer
is used with operational PC and Printer, and can interact with the host computer. The operational
PC consists of the application software for the user to operate the analyzer.
All the samples and reagents for measurements including samples obtained from patients are
controlled by barcodes enabling the analyzer to perform the entire process of the analysis
automatically.
Use of the analyzer with proper knowledge will ensure quality test results and trouble free analyzer
operation and performance.
This operation manual is prepared based on the assumption that the user has knowledge of clinical
chemistry.
XL-180
Part
I
System Overview 1-2
1 System Overview
This section provides an overview of the analyzer and its main features.
Introduction
System description
The results for tested clinical chemistry parameters can be used for screening, monitoring, and
diagnosis. The function is specifically dependent on each parameter and is described in IFU of every
reagent kit provided by ERBA. For professional use in clinical laboratory only.
For more details on how to use XL-180 with ISE, refer “User Manual for ISE”.
1.2 Introduction
It is an advanced integrated system for diagnostic clinical chemistry testing.
It is a random access, discrete, patient prioritized, fully automated clinical chemistry analyzer
designed to meet the needs of modern clinical laboratories in mind for high throughput. Once
programmed, it is a walk-away system.
This analyzer is In -Vitro Diagnostics (IVD) equipment intended to use in pathological laboratories
and hospitals.
Random sample access, innovative robotics, and an advanced user interface, using windows
embedded operating system, optimize time management and streamline work flow.
XL-180
1-3 System Overview
The high performance, flexibility, and versatility of the analyzer make this system suitable as a
routine analyzer as well as a dedicated instrument for specific tasks.
It is a highly sophisticated system and therefore it is of utmost importance that the operator and
service personnel read the instructions and becomes familiar with the operation theory.
1 Data Station
2 Analyzer
Reads the bar-codes on reagent bottles, samples tubes and displays the related information on
the screen.
Calculates and ensures the integrity of the result, generating flags for suspect ones.
Keeps track of all samples, tests, and test’s schedule on the instrument.
Collates results into reports for printing or result transmission to another computer system.
XL-180
System Overview 1-4
The analyzer is an automated clinical biochemistry analyzer based on the principle of photometry, it
measures light transmittance at various wavelengths White light as we see it is actually composed of
several colors. This becomes evident, when we pass a beam of white light through a prism. If the light
emerging from the prism on the opposite side were allowed to fall on a screen, we would see a wide
spectrum of colors, beginning with red on the top and ending with violet at the bottom. The colors
visible in between are in the order of indigo, blue, green, yellow, and orange.
Incident or white light contains the entire spectrum, objects that appear colored, absorb light at a
particular wavelength and reflect others, thus giving different colors. That color is a function of its
wavelength.
Light having a wavelength of less than 400 nm is termed Ultraviolet, where as light having a
wavelength greater than 800 nm is described as Infrared, both ultraviolet and infrared lights are
invisible to the human eyes. Light corresponding to wavelengths between 400 nm and 800 nm is
visible to the human eye and is termed as Visible light.
Beer’s Law
If light is allowed to pass through a colored solution, the solution will absorb some light while the rest
of it will be transmitted. The amount of light absorbed is proportional to the nature, concentration and
color of the solution. (Light absorbed Concentration of the solution).
Lambert’s Law
The light absorbed by the colored solution is directly proportional to the light path of the color solution
(diameter of the cuvette): that is if the cuvette diameter is doubled, the light absorbed will be doubled.
XL-180
1-5 System Overview
Since the total incident light = light absorbed + light transmitted, it follows that:
Therefore as the absorbed light (Absorbance) increases, the transmitted light will decrease.
As we increase the concentration of the colored solution, the light absorbed increases, and we find
that the transmittance varies inversely and logarithmically with concentration.
Analyzer
Data Station
Host
1.3.1 Analyzer
The analyzer features user-friendly operation with minimum operator intervention.
The analyzer comprises of photometer and sophisticated robotics combined with an Operating
Console and Data Processing Unit (DPU). The DPU in the analyzer provides a schedule to the
analyzer, after executing the schedule as per the programmed sequence, the photometric results are
then sent to the analyzer’s computer connected to the analyzer where they are processed, stored
and then reported.
The robotics consists of a Sample and Reagent (SRPT) arm, Sample and Reagent Tray (SRGT),
Reaction Tray, and Syringe.
The SRGT tray holds patient samples as well as Reagents with a total of 50 positions. Routine
samples and necessary reagent are to be loaded on the SRGT tray and the reaction take place in
the Reaction wells.
The instrument carries out all tests automatically and is equipped with measuring modules for
XL-180
System Overview 1-6
Access panels to work on the internal and external parts of the analyzer.
3 Rear Panel
Provides access to connectors of Waste Can, DI water Can, Float sensor, Data cable, Power
supply cable and Main switch [Not shown]
5 Status indicator
Indicates analyzer's ON/OFF status. Light turns to red when secondary switch is OFF, else
display as green.
XL-180
1-7 System Overview
1 Monitor
2 Keyboard
4 Mouse
5 Printer
1.3.3 Host
A host is a computer connected to the analyzer PC.
The clinical laboratory instruments under consideration are those that measure one or more
parameters from one or more patient samples. Often they will be automated instruments that
measure many parameters from many patient samples. This instrument output may include patient
results, quality control results, and other related information.
The computer systems considered here are those that are configured to accept instrument results for
further processing, storage, reporting, or manipulation.
ASTM HOST protocol enables any two such systems to establish a logical link for communicating
text to send result, request, or demographic information in a standard and interpretable form.
Typically, Host software communicating with Clinical Laboratory Instruments is considered here as
Analyzer PC and the computer system considered here is as Laboratory Information Management
System (LIMS/LIS PC).
MultiXL communicates with LIS through Serial Port or TCP/IP. Separate serial port is required to
enable the communication with LIS through serial cable. To enable communication through TCP/IP,
the analyzer PC should be connected to local network.
XL-180
System Overview 1-8
Rear view
XL-180
1-9 System Overview
Access panels to work on the internal and external parts of the analyzer.
1 ISE module
ISE module is situated inside the left side panel. Open door to access ISE module.
Access panels to work on the internal and external parts of the analyzer.
XL-180
System Overview 1-10
2 Connectors
Inlet for DI water Can and Lamp Cooling. Outlet for Waste Can. Connectors for DI water and
Waste Can Float sensors
XL-180
1-11 System Overview
4 SRPT Arm
5 Stirrer
6 Reaction Tray
Reaction tray
Photometer unit
XL-180
System Overview 1-12
The Sample and Reagent pipette unit (SRPT) consists of a probe, the up-and-down movement
mechanism, rotating mechanism, liquid level sensor and probe down limit sensor.
The sample and reagent probe is connected to the syringe pump for sample aspiration via PTFE
tube. This is also equipped with heating element which helps reagent or samples to be preheated
close to 37ºC prior to dispense in cuvettes.
The sample or reagent on the SRGT tray is aspirated by the pipette and then dispensed into the
cuvettes (reaction cells) in the RCT unit.
When an optional ISE unit is fitted and the ISE measurement is performed, the SRPT aspirates
sample and dispenses it into the sample port of the ISE unit for ISE measurement.
The Sample & Reagent tray (SRGT) consists of rotating carousel, barcode reader, rotating
mechanism and optional cooler. SRGT has total of 50 positions in 2 circles described as inner and
outer which can be used as follows:
Maximum 25 reagent bottles with large type (50 ml) containers at inner positions. Small
container (20 ml) can be kept in these positions.
Maximum 15 flexible positions at outer which can be used to place small containers (20 ml) or
can be programmed as sample positions with the help of adaptors provided. It can also
accommodate 5 ml tube for placing reagent using adapter.
The routine Samples, Blanks, Standards, Calibrators and Controls can be placed at any position on
the SRGT’s outer row. Outer row can accommodate 5 ml, 7 ml tubes and 2 ml cups.
XL-180
1-13 System Overview
The reagent tray rotates and the required reagent container or sample is indexed to the desired
position where the reagent or sample is aspirated. It is then dispensed into cuvettes in the RCT unit.
All containers are screw capped to prevent evaporation of reagents while not in use. Bar-code reader
reads bar code labels on the reagent containers for identification.
The barcode reader reads barcode of the label affixed on the outer surface of the sample tube and
reagent containers as shown below. When the reader does not read the barcode even if the bar code
label exists, the appropriate error message is indicated. The barcode reader used is CCD type bar
code reader.
For 5 or 7 ml tubes (outside diameter 12 mm and length 75 mm): For label affix, refer to below
drawing.
XL-180
System Overview 1-14
The resolution of the barcode label should be 0.25 mm. Length of the barcode should be 42 mm and
width should be 10 mm.
Number of digits should be 3 to 18 but the combination of digit and type should be within the
specified length of the barcode label.
Even if the analyzer is turned off (through ON/OFF switch provided on the instrument), the
temperature inside the RGT unit is kept within the specified limits by the Peltier element which is
controlled by temperature controller.
The reaction tray (RCT) consists of the specially designed rotor containing 120 cells, heating element
and rotating mechanism. The heating element is used for maintaining the temperature inside wells at
37ºC (+/- 0.5ºC) constantly. The cuvettes are moved at 36 second step and a series of process
including dispensing of reagents, samples, stirring, and photometric measurement are performed.
The preparations are dispensed in an optical quality PMMA reaction rotor thermo stated at 37ºC. The
optical absorbance readings are taken directly on this rotor. Each reaction can be read for 10
minutes. The readings are taken as they are programmed in each measurement procedure.
The reaction wells have been designed to enable the mixture of the sample and the reagent during
the dispensing. Each rotor has 120 reaction wells. The length of the light path is 5 mm. The minimum
volume required to take the optical reading is 180 µl. The rotor cover must be in place for the optical
system to work correctly.
The wells have a maximum useful capacity of 735 µl. When all the wells in reaction rotor are used,
the user must change it for one that is empty, clean and dry.
The user has a test in maintenance menu of MultiXL software which can be used to check the
condition of the rotor in case of doubt.
XL-180
1-15 System Overview
To improve the efficiency of the photometer, the RCT tray will automatically
come to offset position (such that the beam falls in between two consecutive
cuvettes) on the following conditions:
* After the end of batch run
* When the batch run is manually terminated from Status Monitor by user
* When the batch run terminated due to occurrence of any emergency error.
The Photometer Unit consists of the optical measurement system having narrow bandwidth,
wavelength specific filters with light source. The absorbance inside the cuvette is measured by using
a photometer. Measurement is performed with any combinations of 2 wavelengths selected among
the following 8 wavelengths:
340 nm, 405 nm, 505 nm, 546 nm, 578 nm, 600 nm, 660 nm, and 700 nm
The photometer consists of an illuminant (halogen lamp), lenses, optical filter and photoreceptor
(photodiode). The light passed through the cuvette (reaction mixture) and it is split by beam splitter
which in turn passes through wavelength specific filter on to diode. This eliminates several optical
interferences and greatly improves the efficiency of the photometer.
There is one syringe pump of 500 µl capacity for both reagents as well as sample. The syringe pump
of the analyzer is modular type by which it aspirates and dispenses volumes between 2 µl to 300 µl.
Sample volumes can be increased in steps of 0.1 µl.
The reagents volumes can be increased in 1µl step. The syringe is located behind the front panel of
the analyzer and connected to the probe using appropriate tubing. The syringe unit is shown below.
The Liquid Level Sensor is placed inside the respective Cans of DI water and Waste. The float based
level sensor if senses the low level of DI water in the Can, it gives the beep sound and the respective
LED will turn ON.
Similarly, if full level is detected in the Waste Can the respective LED will turn ON accordingly with
beep sound. All the LEDS are placed just near to the tube connection for the same cans.
XL-180
System Overview 1-16
The concentration of electrolyte (sodium: Na, potassium: K, chloride: Cl, lithium: Li) contained in
serum, plasma or (sodium: Na, potassium: K, chloride: Cl) urine is measured by the ion electrode of
the ISE unit. This unit is optionally supplied.
The ISE unit consists of ISE module, ion electrode, supply and drain pump.
XL-180
1-17 System Overview
1 CAL A Pump
2 CAL B Pump
3 Waste Pump
4 Electrodes
The concentration of the electrolyte (sodium: Na, potassium: K, chloride: Cl, lithium: Li) contained in
serum, plasma or (sodium: Na, potassium: K, chloride: Cl) urine is measured by the ion electrode of
the ISE unit that is placed on the left-hand side of the analyzer. This unit is optionally supplied.
The ISE unit consists of ISE module, ion electrode, supply and drain pump.
ISE module This module unit is fitted with electrodes (Na, K, Cl, Li & Reference)
and controls pumps, measurement of concentration by electrodes and
rinsing movement. Communication to the analyzer is carried out
through RS232C.
Ion electrode This unit consists of Na, K, Cl, Reference and Li electrodes.
The Reagent pack for Calibrant-A and Calibrant-B is placed on the top
cover. Dedicated wash solution are placed in the ASP unit and wash
solution is supplied by the SRPT in the same way as for the sample.
Supply pump These pumps are performs the infusing of Calibrant-A and Calibrant-B
into ISE module.
Drain pump This pump performs the transferring of liquid in ISE module.
Calibrant-A
Calibrant-A is used at the time of one-point calibration.
The one-point calibration is carried out at the same time when the Calibrant-A is dispensed to wash
electrodes every time the sample measurement is performed. 100µl of Calibrant-A is automatically
dispensed into the ISE unit every 30 minutes to prevent the electrode from drying during standby
cycle.
Calibrant-B
Calibrant-B is used at the time of two-point calibration.
The two-point calibration should be carried out at the beginning of the day and at least once every 8
hours or after completion of 50 samples.
Cleaning Solution
The cleaning solution needs to be dispensed into the unit to avoid deposition of protein on the
electrodes.
As necessary, 500µl of the wash solution is dispensed into a sample cup and it is placed on position
of the ASP tray.
This function should be carried out twice a day, once in the beginning of the day before the
Calibration and at the end of day. When more than 50 samples of measurement are carried out,
washing must be carried out.
Diluent
The diluent is used to dilute urine to one-tenth in concentration. It is placed in a reagent bottle that is
XL-180
System Overview 1-18
placed in the RGT unit at the user defined position. The necessary volume for diluting one sample is
200µl. The dilution is carried out using a cuvette in the RCT unit and therefore one cycle of chemistry
analysis is allocated to this processing.
Daily routine
Rotor replacement
ISE unit
1. The DI water Can is filled with pure DI water and the pH of the water should be maintained at
7.0.
2. The Waste Can must be emptied.
XL-180
1-19 System Overview
If the ISE unit is installed in the system, make sure that the ISE tubing’s should be filled with CAL A
and CAL B solutions and air bubbles should not be present inside the tubes. The reagent pack
should have enough CAL A and CAL B content. For this, from the application software, in
Maintenance screen, send ISE Purge A and Purge B commands 3 - 4 times consecutively so as to
clear the path of CAL A and CAL B.
Verify that there should not be any bacterial growth near the electrode placement areas and also
near the inlet port of ISE Module.
Ensure that the following checks are performed before ISE measurement.
1. Before performing measurement with the ISE unit, confirm that Electrode unit (Na, K, Cl, Li
and Reference electrodes) whose term of validity is not expired is installed.
2. The Reagent Pack is filled with sufficient Calibrant-A and Calibrant-B solution.
3. Cleaning was carried out at the end of the last ISE measurement.
4. The Calibrant-A is flowing from the side of sample port by executing of ISE purge.
5. In the following cases, ISE purge should be carried out 5 times or more:
At the first measurement of ISE.
At the time of exchanging the ISE Reagent pack.
At the time of being pulled up the tube from the Calibrant-A.
Just after turning on the analyzer, 3-4 times of ISE purge should be carried out. All electrodes
should be fitted to the ISE module, otherwise the liquid of Calibrant-A is flooded into the inside
of analyzer. It may cause serious problem.
Just before measurement, the DI water can need to be filled with the DI water and the can for diluted
waste have to be empty.
The DI water should have a resistivity of more than 1 Mega Ohm-cm (or conductivity less than 1µS/
cm). Also the pH of the DI Water should be maintained to 7.0.
XL-180
System Overview 1-20
XL-180
Part
II
System Installation 2-2
2 System Installation
This section gives you the detailed explanation on installing analyzer.
Pre-installation
Installation
Read the necessary general safety guidelines before installing the analyzer for the first
time. See Safety Instructions for more details.
The access to the conductive parts within the analyzer may cause serious electric
shock. When removing parts, make sure to shut off the main power supply from
the socket. Leave any maintenance and repair of electrical parts inside the
equipment to qualified service personnel.
General safety:
Keep the analyzer out of the rain and any other water splash.
Danger of explosion through sparks. Do not install the analyzer at the place
adjacent to the storage room of chemicals, or explosive material or the place
where any gas is likely to be generated.
Check the power supply frequency, voltage and current capacity (power
consumption).
Ensure that all the necessary electrical cables are correctly connected.
Check that the contact conditions of switches and indicators are appropriate and
that the analyzer is ready to be activated correctly. Extreme care must be taken
not to result in misdiagnosis or pose any danger to the analyzer or human body
XL-180
2-3 System Installation
In case of serious incident (if any) related to this instrument, report it to the
manufacturer and the competent authority of the member state in which the
user and/or the patient is established.
1. Analyzer is a precision instrument and must be handled by trained personnel only to avoid
damage. Improper handling may cause improper functionality.
2. It is fully inspected and carefully packed before leaving the factory to withstand shocks in transit.
3. The Manufacturer transports the instrument in it's original packing to reach arrive safely.
4. Do not let the instrument or packaging become wet or be exposed to a damp environment.
It is recommended to maintain the below mentioned environment during transportation and storage of
the analyzer.
2.3 Pre-installation
The proper location is an important consideration; a poor location can lead to malfunction of the
analyzer. To ensure the accuracy and precision of the analyzer, you must follow the pre-installation
requirements before installing the analyzer.
Read the environmental and electrical suggestions to ensure the accuracy and precision of the
analyzer.
Electrical requirements
Floor requirements
Room lighting
External interferences
This will also ensure a high level of operator and technical service personnel’s
working comfort and safety.
XL-180
System Installation 2-4
Make sure that no Reagents or Samples are placed on top of the analyzer as they could spill
causing a permanent damage to the analyzer.
A proper grounding is highly essential for safety and proper functioning of the
analyzer.
Single-phase continuous stabilized AC 220 volts ± 10%, 50/60Hz or AC 110 volts ± 10%, 50/60Hz
supply. The analyzer comes equipped with a three-pin power cord. The type of cord and plug
depends on the source voltage for the system.
Grounding
It is absolutely necessary that the perfect grounding must be provided to the power source with all
applicable local requirement (only a certified grounded, 3 pin power plug should be used).
Plug points
Four 5Amp sockets must be available near the analyzer (Four sockets are required, one each for
the analyzer, computer, monitor and printer.
It is recommended that two extra sockets be provided near the analyzer, for use by a measuring
equipment or engineering tool if required while servicing (example Oscilloscope, Soldering iron
etc). Heavy-duty electrical devices like air conditioners, refrigerators, ovens etc. should not be
operated on the same electrical lines as the analyzer.
Improper grounding the analyzer by passes important safety features and may
result in an electrical hazard.
Use the regulatory approved converter to avoid any damage to the analyzer.
Follow the instructions provided with the converter manual to connect the
converter to the Mains input 110VAC.
XL-180
2-5 System Installation
Ensure the selected 110VAC mains input point is well grounded (earthed).
XL-180
System Installation 2-6
The room should be free of vibrations from heavy duty devices like centrifuges and
compressors.
The room should be free from strong magnetic fields caused by other medical equipment, like
CT Scans, MRI etc.
There should not be a variation of more than 2 degrees in room temperature per hour.
The relative humidity should be in between 40% to 80% and should be non – condensing.
2.4 Installation
The analyzer should be installed by the trained service engineer.
The analyzer is fully inspected before leaving the factory and carefully packed to withstand shocks in
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2-7 System Installation
transit.
On receiving the analyzer, check the package externally; make sure that there is no external visible
damage to the shipping container if there is damage please make a note of it, if possible photograph
it and inform the manufacturer immediately. Verify with the invoice, if all the boxes have arrived.
Receiving Information
Accessories Checklist
Software Installation
This section describes you the basic guidelines or information on analyzer's receiving instructions
and warranty.
Receiving instructions
Warranty instructions
Check to see that the arrows on the sides of the packages are pointing up. If the arrows do not
point up, make a remark about this on the invoice copy.
Visually inspect the outside of the package for rips, dents, or possible shipping damage.
Document any sign of damage on the bill of landing, regardless of how insignificant it may
appear. This is to protect your interests.
Notify your service representative that the analyzer system and its components have arrived.
Wait for your local service representative to unpack the system and open the packages.
Follow the unpacking and storage instructions provided on the outside of the package. Special
requirements such as refrigeration are clearly marked on the outside of the cartons and will be
included in the unpacking instructions and pack inserts.
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System Installation 2-8
This warranty does not cover any defect, malfunction or damage due to:
Accident, neglect or willful mistreatment of the product failure to use, operate, service, or
maintain the product in accordance with the applicable Operator Manual and Service Manual
The analyzer is packed carefully to prevent any shipping damage. Upon arrival, inspect the packing
according to the list and modify the carrier of any apparent damage.
Remove the front panel of the wooden box by loosening the bolts. The front panel on the
wooden box is marked.
Remove the top and side panels of the wooden box as a whole section by loosening the bolts
from the back panel side.
Remove the four “Z” brackets, which are holding the analyzer on the pallet.
Lift the instrument with the help of handle provided on both sides of the analyzer. Handles
needs to be pulled out underneath the panels.
Place the analyzer at the desired place keeping the floor requirement given above in view.
Contact authorized service personnel for removing analyzer from use for repair
and maintenance.
Follow regional or international norms for disposal of analyzer once end of life.
Printer
DI water plant
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2-9 System Installation
2 -- SOFTWARE CD 1 NOS
Shipper Box
P.M. Kit
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System Installation 2-10
Printer installation
2.4.4.1 Connecting communication cable between data station computer and analyzer
1. Unpack the USB interface cable from the accessories box, and connect its one end to the
USB port of the computer and other end to the instrument’s USB port as shown.
2. Connect the one end of the power cord to the analyzer’s power outlet at the back side and
other end to the main switch as shown in figure below:
Make sure that the power outlet button should be in OFF condition.
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2-11 System Installation
1. Unpack the Sample and Reagent tray from the accessories box.
2. Gently place the sample and reagent tray into the container, make sure that the index pin on
the tray, slides into the index hole provided on the sample and reagent tray.
3. Unpack the Sample and Reagent tray lid, and place over the Sample and Reagent Tray.
4. Make sure that the index pin on the Reagent lid slides into the index hole provided on the
Sample and Reagent tray lid.
2. Place the Rotor tray on the rotor tray assembly by matching the smallest rotor holder with
smallest slot as shown in the following figure.
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System Installation 2-12
3. Now tighten the rotor tray with the knob provided, as shown in figure below.
4. Unpack the rotor tray lid, and place over the rotor tray.
1. Unpack the Float Sensors for the CANS and place them on one side.
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2-13 System Installation
2. From the accessory box, remove the 4 liters DI water CAN and 4 liters Waste CAN and put
them on floor.
3. Connect the longer Float Sensor with blue sleeve for DI Water and smaller Float Sensor with
yellow sleeve for waste CAN respectively in the small outlet provided on the canister of both
the CANS.
5. Remove the tubes from the accessory box. Connect one end of the 2 meter. (1/8” x 3/16” size)
Tygon tube to the analyzer inlet marked DI WATER, and connects the other end to the steel
tube on the DI Water CAN.
6. Take another tube of same size and connect the one end of it to the analyzer outlet marked DI
WATER – LAMP. Connect another end of the tube on canister of DI Water CAN connector
marked as DI WATER LAMP.
7. Take another tube of size 1/8” x 3/16”. Connect one end of this tube to the remaining yellow
color connector on analyzer with the other end on connector provided on Waste CAN.
5. Print a test page from the analyzer computer to confirm correct printing.
1. Unpack the Test Loader device,Test Loader stand and USB cable from the accessories as shown
in below figure
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System Installation 2-14
2. Place USB -B end of USB cable inside the Test Loader stand as shown in below figure.
5. Once connected to analyzer PC, it gives the beep sound that means now Test Loader is ready to
scan.
6. To ensure if Test loader device is connected to analyzer PC, go to Start > Computer > right click
> Manage as shown in below screen
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2-15 System Installation
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System Installation 2-16
10. It detects HID – compliant device that means Test Loader is connected with the analyzer PC.
OR
11. Go to Start > click Devices and Printers ; following screen will be displayed;
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2-17 System Installation
12.It detects the HID device, that means Test loader is connected with analyzer PC.
14.Now Keep the System Reagent pack in front of scan side of Test Loaderr device as shown in
below figure.
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System Installation 2-18
15.Go to Status Monitor > Scan Pack > System Pack details > Scan Pack,scanned details will be
displayed on analyzer PC.
Do not disconnect the device while scanning and registering the pack. It
may damage the device .
16.If Test Loader device is unconnected following message will get displayed.
17.Check the connectivity of Test Loader device by following above steps 6-12.
18.If Test loader device is unconnected, device manager can not detect the HID device.
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Part
III
Software Installation 3-2
3 Software Installation
This section guides you through the installation and un-installation procedure of MultiXL software.
You must read the instructions carefully before installing the software.
See the following sections in more details:
Pre-requisites
Software installation procedure
Read the necessary general safety guidelines before installing the software for the first
time. See Safety Instructions for more details.
3.2 Pre-requisites
Make sure that you should have the following pre-requisites before installing the software.
System configuration
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3-3 Software Installation
MONITOR Color Monitor with 1024*768 resolution support, 17” & above
Remove firewall and other security software and / or settings from the analyzer PC.
Do not run any other application on the analyzer PC during batch run on analyzer.
Ensure that the default printer (Laser Jet / DeskJet) is configured and connected to the
analyzer PC.
Delete the “Microsoft XPS Document Writer” from the system. To do this, click Start
button, and click Control Panel. Now, under the Category view, go to Hardware and
Sound > Devices and Printers. Right click on the Microsoft XPS Document Writer,
and choose Remove Device to delete.
Disable screen-savers and power management on analyzer PC before starting the application
software.
Use the following procedure for disabling the screen saver and power management:
1. Open Screen Saver Settings by clicking the Start button, clicking Control Panel, clicking
Appearance and Personalization under Category view, clicking Personalization, and
then clicking Screen Saver.
2. To turn off all screen savers, under Screen Saver, select (None) from the drop-down list,
and then click OK.
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Software Installation 3-4
3. Now click on the link Change power settings (Applicable only if option is available). The
following screen will be displayed.
5. Click on the link Change advanced power settings. The following screen will be
displayed. Set Turn off hard disk after to Never.
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3-5 Software Installation
6. Similarly apply same settings to Power saver option. Repeat the step 3 to 6.
1. Open User Account Control Settings by clicking the Start button, and then clicking
Control Panel. Under Small or Large icons view, click on User Accounts and then,
again click User Accounts. The following window will be displayed.
2. Now click Change User Account Control settings. The following screen will be
displayed.
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Software Installation 3-6
4. You must re-start the analyzer PC to turn on the user account control.
Ensure that the following regional and language settings are appropriate. Note that these are the
critical settings for the communication with the analyzer.
Use the following procedure for setting the regional and language options:
1. Click on Start and open Control Panel. Under Category view, click on Clock, Language
and Region. The following Region and Language screen will be displayed. Following
should be the settings for Formats tab.
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3-7 Software Installation
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Software Installation 3-8
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3-9 Software Installation
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Software Installation 3-10
Remove all memory resident software including anti-virus software from the Analyzer PC if
installed. Use the following procedure:
Click Start button, and click Control Panel. Now, under the Category view, go to
Programs > Programs and Features. Select the desired anti-virus software from the list,
and click Uninstall.
Remove firewall, automatic update, other security software and from the Analyzer PC.
Click Start button, and click Control Panel. Now, under the Category view, go to System
and Security > Windows Firewall, and click on the link Turn off Windows Firewall on
or off. Now select the option Turn off Windows Firewall (not recommended), and then click
OK button.
To turn off automatic updates, under Control Panel, go to System and Security >
Windows Update, click on the link Change settings, and select the Never check for
updates (not recommended) from the drop down list, and click OK.
Do not run any other application on the Analyzer PC during batch run on Analyzer.
Ensure that a default printer (Laser Jet / Desk Jet) is configured and connected to Analyzer
PC. Set appropriate printer as default printer.
Delete the “Microsoft Office Document Image Writer” and “Microsoft XPS Document
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3-11 Software Installation
Click Start button, and click Control Panel. Now, under the Category view, go to
Hardware and Sound > Devices and Printers. Right click on the Microsoft Office
Document Image Writer, and choose Remove Device to delete. Similarly, delete
“Microsoft XPS Document Writer”.
Windows Login User requires Administrative privileges to Install and Run the Application.
Disable Screen-savers and Power Management on Analyzer PC before starting the Application
Software.
Use the following procedure for disabling the screen saver and power management:
1. Open Screen Saver Settings by clicking on Control Panel > Appearance and
Personalization under Category view, click Personalization, and then click Screen
Saver.
2. To turn off all screen savers, under Screen Saver, select (None) from the drop-down list, and
then click OK.
3. Now click on the link Change Power Settings / Power Options (Applicable only if option is
available). The following screen will be displayed
4. Click on Balanced radio-button and then the corresponding Change plan settings button as
shown above.
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Software Installation 3-12
5. Click on the link Change advanced power settings. The following screen will be displayed.
Set Turn off hard disk after to Never as shown below;
6. Similarly, apply same settings to Power saver option. Repeat the step 3 to 6.
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3-13 Software Installation
1. Select Control Panel. Now, under the Category view, go to System and Security >
Security and Maintenance . Move Pointer to Never Notify and click OK. The
following screen will be displayed.
2. Now, click on Change User Account Control Settings option as shown above. The
following screen appears;
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Software Installation 3-14
4. You must re-start the analyzer PC to turn on the user account control
Ensure that the following regional and language settings are appropriate.
Note that these are critical settings for the communication with the analyzer.
Go to Control Panel > Clock, Language, and Region options > Change the date, time and
number format.
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3-15 Software Installation
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Software Installation 3-16
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3-17 Software Installation
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Software Installation 3-18
Test Loader device scans the details of System Pack Reagent kits including lot number,
expiry date, pack size etc.
Analyzer performs open/closed-channel tests only after scanning the System Pack Reagent
kits.
Analyzer performs closed channel tests based on pack size (test count) of respective
reagent kit.
Analyzer performs open channel tests not exceeding the total test-count, as read from
System Pack Reagent kits. Open channel tests can also be loaded using special cards
which may be available for purchase from manufacture in special circumstances.
System will intimate user about expiry of open test counts (for cards expiring soon) as read
from the special cards / System Pack Reagent kits.
Once open test-counts are exhausted, it is not allowed to perform further open tests, until
user scans the new System Pack Reagent kits.
System will intimate user during run if open test count reaches 10 & below.
Follow the instructions in this section, in case, you are installing the software for the first time on the
PC i.e. there is no previous installation of the software on the PC. See the following sections in more
details:
Installing MultiXL
Installation of Database
Upgrading MultiXL Software (to upgrade MultiXL from existing version to the new version)
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3-19 Software Installation
1. Insert the installation CD into the CD drive of your computer. On inserting the CD, the MultiXL
Installation screen will be displayed.
OR
OR
2. Click on Explore and double-click on Launcher.bat. The following screen will be displayed.
3. Click on Install MultiXL Application & Database link and follow the on-screen instructions.
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Software Installation 3-20
OR
3. Click on the Browse this CD link. The software installation CD contains the following folders
and files as shown in the figure below:
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3-21 Software Installation
This screen will not be displayed if .NET framework 4.0 is already installed on
your computer.
This screen will not be displayed if Crystal Reports for .NET framework 4.0 is
already installed on your computer.
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Software Installation 3-22
This screen will not be displayed if SQL Server 2005 Express Edition is already
installed on the analyzer computer.
8. In some scenarios, following screen may appear while installing MultiXL Application. Please
click on Run Program button to continue with MultiXL Installation.
.
It is not necessary to apply SQL Server 2005 Service Pack 3 (SP3) or later
Service Pack as shown in the above screen shot.
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3-23 Software Installation
Wait until the setup wizard is visible on the screen as shown below.
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Software Installation 3-24
On selecting Configure Database checkbox, the installer will create or upgrade the
database after completing the installation of MultiXL (If Database is found present then the
existing database will be upgraded to the latest version. If Database does not present then
the installer will create a blank Database). If this option is unchecked, the blank database
will not be installed and you have to install it manually.
The installer will install the software in the default location C:\Program Files\MultiXL.
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3-25 Software Installation
12. Ensure that “Everyone” is selected, and click Next. On clicking, the following window will be
displayed. Click Next to confirm the installation.
13. On clicking Next, the installation is started and the status will be displayed, as shown
below.
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Software Installation 3-26
The following screen will be displayed if the Configure Database option is selected.
Once the installation completes, the software icon will be created on the desktop and the
following screen will be displayed.
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3-27 Software Installation
14. Click on Close to close the screen and restart the computer.
Now double click on the MultiXL icon from the desktop or choose Start > All
Programs > MultiXL to start the application.
The Detect Regional Settings screen will be displayed and the application
halts in case, if the language setting in the Formats tab is other than English
(United States).
.
See section Region and Language Settings for more details.
The following observations are noted after installing MultiXL on Windows 7 Embedded operating
system:
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Software Installation 3-28
The windows key (left and right) will be disabled from the keyboard. Logging of MultiXL
start and shutdown events (for internal use).
Full MultiXL database backup and log files are automatically archived in the C
drive under MultiXLLog folder, after every seven days before system shutting
down.
Restricted user account for MultiXL: To install and uninstall any application from the PC, you
must be logged on as (windows) user “Administrator”. To log in to the administrative account,
go to Start > Shutdown > Logoff and then click the Administrator icon and provide the
administrator password. The default administrator password is tbm1234@.
Database installation is required only if the Configure Database option was de-selected during
installation.
In case, Configure Database option is selected (ticked by default) during Software Installation then
the Database will be created / upgraded automatically as part of installation. (Database, when
already exists, will be upgraded to the latest version. When database is not found on PC, then the
installer will create a blank database).
In case, the Configure Database option is not selected, then the database should be installed
manually, as follows.
Refer to the folder Database Utility in the CD, which consists of DatabaseUtility.exe for installing
(restoring) the Database file MultiXL.BKP.
1. Click on Run Database Utility from the MultiXL installation screen as shown below.
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3-29 Software Installation
OR
1. Open the Database Utility folder from the software installation CD, and double-click
DatabaseUtility.exe.
2. Click on CHECK DATABASE. This command will check for the existing database on your
computer. If no database is available, a message is displayed on the following screen.
3. Click on CREATE DATABASE. This will create the database. If archive or Temp Database is
not available then utility will ask for Blank Database location and the following window will be
displayed.
4. Now click OK and select the blank database file MultiXL.BKP from the software CD, and then
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Software Installation 3-30
click Open.
5. After some time, the database will be created successfully and the following screen will be
displayed.
6. Once the database is created, click CHECK DATABASE to ensure the proper creation of the
database. The following screen will be displayed.
The above screen indicates that the database is created successfully. Click Close to exit from
the utility screen. Now you can access the MultiXL application. (Refer section Accessing MultiXL
Software for more details).
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3-31 Software Installation
To check the installed software versions, go to Service Check screen, right click
on the Misc Commands button, and choose EMB Software Version option.
Upgrade Software
Upgrade Database
Take a database backup through Utility > Backup, before proceeding with
software upgrade.
Un-installing Software
1. Click on the Uninstall MultiXL Application from the MultiXL Installation screen as shown
below.
OR
.
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Software Installation 3-32
2. Select the MultiXL, and then click Uninstall. On clicking, the software will be removed
from the computer.
Database can be upgraded to match the newer software version without deleting the database of the
existing version.
Upgrading Database
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3-33 Software Installation
1. Click on the Run Database Utility link from MultiXL Installation screen as shown below.
OR
1. Open the Database Utility folder from the software installation CD. Double-click on
DatabaseUtility.exe.
2. Click UPGRADE DB. A window will appears to select the upgrade script file, see the
following screen.
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Software Installation 3-34
3. Select the upgrade script file from the software CD, and then click Open.
This will start the upgrade process. If archive database is not available then the utility will
prompt to select the path for blank database and the following screen will be displayed.
4. Click OK and select the blank database file MultiXL.BKP from the software CD, and then
click Open.
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3-35 Software Installation
5. After some time, the database will be upgraded successfully and the following screen will
be displayed.
After successful database upgradation, you can access the MultiXL application. Refer
section Accessing MultiXL Software for more details.
After installing the new software version, if the database is not upgraded
using the upgrade script file provided in the Software CD then the following
screen will be displayed on starting the application software. This screen
indicates the software and database version mismatch.
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Software Installation 3-36
In case, the Software and Database version mismatch screen is displayed; upgrade the
database using the script file, provided in the software CD. Refer section Upgrading
Database for more detail.
If the problem is not resolved, then call service engineer for help.
Database backup
Change database
OR
1. Open Database Utility folder from the software installation CD, and double-click
DatabaseUtility.exe.
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3-37 Software Installation
4. Select the path to store the backup file, and then click Save. On successful completion of
database backup, following screen is displayed.
If archive database is present then backup will be stored with “ARH” extension with the same
file name.
For example: In this case Archive Backup will be stored on the same path with File Name
“MultiXL2522011.ARH”. The default file name contains “MultiXL” (the application name),
followed by date, month and year.
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Software Installation 3-38
Before installation, you should take the backup of the database before deleting
or changing the database.
1. Click on the Run Database Utility from the MultiXL Installation screen.
OR
1. Open the Database Utility folder from the software installation CD, and double-click
DatabaseUtility.exe.
3. Click on DELETE DATABASE to delete the existing database. The following screen will be
displayed.
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3-39 Software Installation
4. Click on Yes to continue with database deletion. On clicking, the warning message will be
displayed to re-confirm the deletion.
5. Click Yes to continue. On clicking, a message will be displayed to take the database
backup before deletion.
6. Click Yes to take the backup. The following window will be displayed. Select the
appropriate location for saving the backup database.
On clicking No, the Live and Archive data will be deleted without saving the database.
On clicking, a copy of database will be saved in the desired location. The following screen
will be displayed after successful deletion of the database.
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Software Installation 3-40
OR
1. Open Database Utility folder from the software installation CD. Double-click
DatabaseUtility.exe.
3. In the DATABASE RESTORE UTILITY window, click on the BROWSE FILE. Select the
location where the backup database file is saved.
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3-41 Software Installation
4. Select the appropriate database file and then click Open. The following screen will be
displayed.
5. Click on CREATE DATABASE to create the database. The database create the database
following screen will be displayed.
If the Archive is not available then utility will ask for blank database
location.
6. Click OK and select the blank database file MultiXL.BKP from the application CD.
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Software Installation 3-42
Now you can access the MultiXL application. (Refer section Accessing MultiXL Software for more
details)
1. Click on the Run Database Utility from the MultiXL Installation screen.
OR
1. Open the Database Utility folder from the software installation CD. Double-click
DatabaseUtility.exe.
2. Press F11 key from the keyboard. The following window will be displayed. Navigate to the
appropriate location where the archive database is saved and then click Open.
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3. After archiving the database successfully, the following screen will be displayed.
Team Viewer is used to access analyzer computers, which makes it an ideal solution for Remote
Monitoring and Trouble Shooting purposes.
Team Viewer connectivity depends upon the Internet speed available at the
Lab/Site and load on analyzer PC. Team Viewer uses remote desktop
technology to control a computer from an alternate location. The main cause of
lag when controlling a remote computer is network speed.
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Software Installation 3-44
the gaps in data. Use the Start menu's search box to locate these programs.
Viruses also impact performance. Update your virus definitions and complete a
full system scan.
Installation Procedure:
1. On insertion of CD on Auto-play, MultiXL Installation screen will be displayed with the option to
install Team Viewer.
OR
1. Go to Windows Explorer and Right Click on CD/DVD ROM-Drive and Click on Auto-play.
2. Click on Install Team Viewer. On selection of this option, following pop-up appears;
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3-45 Software Installation
3. Team Viewer installation is carried out at default installation location C:\Program Files\
TeamViewer.
4. After Team Viewer is installed successfully, above screen will be closed automatically and user
will be redirected to the Launcher Screen.
Open Team Viewer 10 Host from Windows Start menu. Following screen appears;
Team Viewer ID (Your ID marked in Red in above image) is unique for every device. This ID of the
Analyzer PC is required for connecting another Remote PC through TeamViewer. Password is
“tbm1234@”, by default.
Analyzer user / operator has to share Your ID (Team Viewer ID marked in RED) to the support
team for Remote Support (Remote control session on Analyzer PC).
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Software Installation 3-46
Do not change the default password for the seamless remote support.
On successful installation, the MultiXL software application will be launched automatically at every
PC startup.
When the MultiXL application is running, all windows shortcut keys (e.g. left and right window keys,
etc) available on the keyboard is not accessible.
When starting MultiXL first time, the product login screen as shown below will be displayed.
Enter the appropriate details in the PRODUCT LOGIN, PASSWORD and LOCATION. Then, click
OK. On clicking, the login screen as shown below will be displayed.
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Enter the following details, and then click OK. You may use this Login details for the first time and
create the other login IDs with appropriate user access rights. See section User Rights for more
details.
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Software Installation 3-48
When you start the MultiXL application first time without connecting the
analyzer, the application title bar will displays “CS” after MultiXL version
number on top which indicates Closed System.
MultiXL version number with "TLS" indicates Test Loader System.
Whether the system installed is Closed System or Open System or Test Loader
System will be automatically detected when analyzer is connected and
switched ON.
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Part
IV
Safety Information 4-2
4 Safety Information
Before operating the analyzer, it is necessary that you read and understand the safety instructions,
safety precautions and warning labels listed below.
Safety Symbols
Warning Labels
Safety Precautions
DO NOT TOUCH
BIOLOGICAL HAZARD
DANGER OF BURNS
BIOLOGICAL RISKS
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4-3 Safety Information
Labels Location
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Safety Information 4-4
Only qualified and trained personnel should use the analyzer and perform the procedures
described in this document.
General safety:
Pay attention not to exceed the time and volume necessary for diagnosis.
Keep monitoring the behavior of the whole system in order to detect any
malfunction.
Turn off the power after every operation so that control is restored to its
previous state as directed.
Do not remove the line cord plugs from receptacles by pulling the cords so
that no undue stress is developed in the cords.
If the auto maintenance at shutdown is not performed, wipe the probe tips of
SRPT several times with cloth or by rubbing alcohol before the analyzer is
used. At this time, do not forget to put medical rubber glove. Pay attention to
prevent bare skins of hands or arms from being touched by or pricked with
the probe tip.
Keep the analyzer out of the rain and any other water splash.
Avoid areas adjacent to the storage room of chemicals or areas that are
likely to generate gasses. Avoid areas that are likely to be subject to
inclination, vibration and shock.
Organize and store parts and cords associated with the analyzer after
they have been cleaned.
Keep the analyzer clean not to cause any inconvenience to the next
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4-5 Safety Information
use.
Electrical safety:
The access to the conductive parts within the analyzer may cause serious
electric shock. When removing parts, make sure to shut off the main power
supply from the socket. Leave any maintenance and repair of electrical parts
inside the equipment to qualified service personnel.
Always replace the halogen lamp with the new lamp only after been kept off
for 30 minutes, to avoid the danger of burns. Keep hands away from the
glass part of the new halogen lamp. Make sure that there is no crack or
breakage in the glass part.
Biological safety:
Never touch patients' samples, SRPT probe, Rotor’s reaction cells, and used
pipette tips with bare hands to prevent operator from possible infection. Wear
disposable medical rubber gloves to keep skin from direct contact with
patients' samples.
The direct contact with bio-wastes and used Rotor may cause infection.
Handle them with gloved hands without exception. Follow the national or
local laws and rules when they are thrown out. There are two kinds of liquid
wastes drained from this analyzer, i.e. high- and low-concentrated wastes.
Treat the drain water as infectious waste. Collect the drain water in reserve
can and allow it to be disposed of by expert distributors.
Wipe the nozzle tips of SRPT several times with cloth or by rubbing alcohol
before the analyzer is used. At this time, do not forget to put medical rubber
gloves. Pay attention to prevent bare skins of hands or arms from being
touched by or pricked with the nozzle tip.
Treat the drain water as infectious waste. Collect the drain water in reserve
can and allow it to be disposed of by expert distributors.
Sample handling:
Do not touch the samples, mixtures and waste liquids with bare hands. Give
special consideration to keep skin and mucous membrane from contact with
reagents to prevent operator from possible infection. Always wear disposable
medical rubber gloves, goggles, etc. to keep skin and mucous membrane
from contact with reagents.
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Safety Information 4-6
In case any samples come in contact with your skin, thoroughly rinse the
area that came in contact with the sample and consult a physician.
Reagent handling:
After unpacking the reagents, be sure not to allow dust, dirt or bacteria to
come in touch with the reagent.
Take care not to spill the reagent. If it spills, wipe it off immediately using a
wet cloth.
If a reagent comes in contact with your eye, wash it off immediately using
plenty of water, and take medical treatment at once.
If you swallow it inadvertently, call for a doctor immediately and drink plenty
of water.
Some reagents are strong acids or alkalis. Exercise great care so that your
hands and clothing do not come into contact with reagents. If your hands or
clothing come into contact with either reagent, immediately wash them off
with soap and water. If a reagent comes into contact with your eye(s),
immediately rinse with water for at least 15 minutes..
Sample probe
DI water pump
Halogen lamp
Refer section Replacement schedule for spares and consumable for more
details.
Ensure that the analyzer operates normally and correctly, when it is reused
after being unused for some time.
XL-180
4-7 Safety Information
XL-180
Part
V
5-2 Technical Specifications
5 Technical Specifications
This section describes the technical specification. See the following:
General Specification
Installation Conditions
Sampling Unit
Reagent Unit
Reaction Unit
Data Processing
Control Unit
Item Description
System type Discrete, open, automated, random access, patient prioritized, 1/2
Reagent system
Sample Serum
Urine
Whole Blood
Others (CSF, Plasma, etc.)
XL-180
Technical Specifications 5-3
25 positions fixed
15 flexible
2 additional positions at room temp.
Programmable Unlimited
parameters
Reaction temperature 37 °C
Temperature stability: ± 0.5 °C
Reaction time Depends on the designated cycle time and number of reagents used
For 1 step assay (using R1)
612 seconds (10.2 min)
For 2 step assay (using R1 and R2)
1st reaction 306 seconds (5.1 minutes) + 2nd reaction 306
seconds (5.1 minutes)
Test selection Setting of tests one by one or with profile key for each sample
Group order entry is possible
Setting from host computer via interface having ASTM protocol
compliance (optional)
Setting according to bar-code data on sample container (Optional
fixed bar code reader)
Barcode identification Sample tube barcode ID (NW7, code 39, code 128, 2 of 5 interleaved,
2 of 5 standard, ISBT-code 128) – 6 to 18 digits Reagent barcode ID,
XL-180
5-4 Technical Specifications
Display PC Monitor
Item Description
STAT samples STAT samples are measured preferentially (To be placed in any of the
25 sample positions on the outer rim)
Calibrators may be placed at any of these 25 positions
Interrupt permitted even during analysis
XL-180
Technical Specifications 5-5
Dead Volume
Item Description
Reagent dispensing Pipetting system with Sapphire Pump, driven by stepping motor
Single preheated probe Micro-pipette with level sensor ( Same probe as for sampling)
for dispensing Samples Washing solution
and Reagents Outside: DI water
Inside: DI water passed through preheated probe.
Equipped with vertical obstruction detection facility to prevent probe
crash
XL-180
5-6 Technical Specifications
Reagent protection Reagent tray cover protection from evaporation, dust, and direct light
Carry over actions Reagent, Detergent or System Wash given for Carry Over Pairs
Item Description
Mixers Mixing by stirrer with 3 speed levels - Low, Medium & High
Item Description
Wavelength 8 wavelengths
340, 405, 505, 546, 578, 600, 660, and 700 nm
OD range OD 0 – 3
Light path calculated as 10 mm
Resolution 0.0001 OD
XL-180
Technical Specifications 5-7
Item Description
Calibration curve K-Factor, Linear (one point, two point and point to point), 4P Logit-log,
5P Logit-log, Cubic Spline, Polynomial, Exponential
Multipoint curves up to 10 points
One point correction to multi-point calibration line is provided (Selective
Calibration)
Automatic dilution line created
Quality control Within day as well as day-to-day X-Mean and R control diagram (L-J
Graphs)
Mean, SD, %CV, R are calculated for each chemistry
Report Report generation: Patient wise, Test Wise, Date wise, Sample wise,
Doctor name wise, Test wise, Location wise, Abnormal result wise,
Graphical Format.
Lists: Abnormal values list, Re-calculated results list, Repeat run list.
A log of number of tests performed covering samples, blanks,
calibrators & controls and reagent consumption will be provided.
XL-180
5-8 Technical Specifications
Alarms and notices Notices: Defined Erroneous operation, mechanical position error for
arm, trays, data processor hardware error, defined erroneous test
results and dome opening.
Alarm level: Notice, temporary halt of analysis, suspension of analysis,
system stop
Audio Alarms: Beep for rotor change, DI water can empty & waste can
full.
Item Description
Item Description
XL-180
Technical Specifications 5-9
Item Description
XL-180
Part
VI
User Interface 6-2
6 User Interface
You can control the day-to-day operation of the instrument through the MultiX L s oftware. This section
describes the main features of the user interface and how to move between the various screens.
Screens
1 Main menu
Click on any menu item to display the corresponding screens.
2 Navigation button
Click to navigate first, previous, next and last records.
3 Command buttons
Click to print, save, clear, edit and delete.
4 Text box
To enter the data for that field.
5 Drop-down list
Allows the to choose one value from a list.
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6-3 User Interface
6 Dotted button
Click to select and enter data for that field.
7 Check box
When selected, that a particular feature has been enabled.
8 Indication box
Provides help or warning messages.
9 Tests
Click to select the test.
1 Radio button
To choose only one of a predefined set of options.
2 Crossed button
To clear the text for that field.
3 Calender button
To select the date.
XL-180
User Interface 6-4
F8 This s c reen is us ed for s earc hing pat ient res ult s , c alibrat ion/
c ont rol res ult s , pat ient s , c ons umables or t es t det ails .
F9 This s c reen is us ed for viewing pat ient report s , c alc ulat ing
s t at is t ic al dat a us ing Tes t S t at is t ic s s c reen, viewing res ult s
on Res ult Reprint s c reen, V iew t he c alibrat ion of a t es t over a
period of t ime on Calibrat ion Trac e, V iew t he c urrent
c alibrat ion on Calibrat ion Monit or, Log of all t he errors on
E rror Log s c reen, reac t ion c urve of t he res ult s obt ained on
Reac t ion Curve s c reen and Reagent c ons umpt ion on Ot her
s c reen.
XL-180
6-5 User Interface
6.3 Screens
This section describes the following sections in more details:
Patient Entry
Test Parameters
Profiles/Calc
QC/Calibration
Consumables
Status Monitor
Search
Reports
Master
Utility
Service Check
Maintenance
Settings
Shutdown
Patient Entry is used to enter the patient details like name, address, doctor referring patient, analyst,
age, gender etc can be entered using this screen. Also, the routine tests, calculation items, profiles
to be performed on the patient sample can be requested using this screen. These patient
demographics are used to generate the patient report after analysis of the sample.
One for defining information related to Sample definition and other for Patient demographics entry.
Commands buttons available for clearing the patient schedule, checking work list, mask tests and
copy tests.
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User Interface 6-6
Clear Schedule
Work List
Copy Tests
Mask Tests
Parameters Description
Sample ID This field is used for assigning an alphanumeric identification number of up to
18 characters to each patient. Entry in this field is compulsory and cannot be
skipped. If the Sample ID is already entered, then the user can view the
Sample ID by clicking on the dotted button placed next to the Sample ID field.
Position In case the sample is not bar-coded, the user should specify the sample
position in this text box. An assigned sample position cannot be used for some
other sample. Any sample Positions on the sample tray can be entered. If
there are more than maximum no of Sample Positions, then a different Group
No. needs to be selected.
For bar-coded samples the sample position is automatically assigned as per
the group number selected after the sample bar-code scan.
For the emergency sample, any position that is vacant can be used for any
group during Patient Run.
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6-7 User Interface
Group No This field is used to assign group numbers for various samples processed
during the day. If there are more than maximum sample positions, then the
user needs to select Group No 2 and so on. The user can assign the Group
Numbers from 1 to 99.
Emergency Whether the given sample is an emergency sample or not is specified using
this tick option. To designate a sample as an emergency sample, tick in this
field and assign one of the free positions for the sample. Emergency samples
are given priority over routine samples in a run.
Barcoded The user can select whether to use sample bar-code facility or not. If the bar-
code option is set to ON in the Settings > System Parameters screen, then
the sample position fed by the user is ignored. The user has to select/deselect
the checkbox for whether the sample for the particular patient is bar-coded or
not. The barcoded option can be selected to only the outer two rings of sample
positions.
During Run, changing status from non barcoded to barcoded is ignored (not
saved) for a Sample ID in progress.
Sample Type Select the sample type from the drop down list. The default options available
are: Serum, Urine, CSF, Plasma, Whole Blood and Other
Sample Select the sample volume type using the drop down list. The available options
Volume Type are Normal, Increase and Decrease. The default value is Normal. User may
select Increase or Decrease, in case the sample concentration is roughly
known. If the sample has low concentration then the user can select an
increase volume. If the sample is high concentration sample, then the user can
select decrease volume.
Container Select the sample container type from the pull down option. There are various
Type options available and one can select the Container Type by selecting the drop
down list.
Registration This field is used to enter the date at which the patient was registered in the
Date hospital.
Collection
This field is used to enter the date at which the sample was drawn.
Date
Sample Remarks about sample can be fed here using up to 50 alphanumeric
Remarks characters. Previously fed remarks can be selected by pull-down options. The
remark is printed in the patient report.
Area This is used to select the area / location from where the sample is collected.
One can select the area list by clicking on the dotted button. On clicking the
dotted button, area help screen is displayed. From the list displayed on screen,
user can select the desired area by double clicking on the particular name.
This area will be printed in Patient Report as Location. User may define area /
location from Master -> Area screen.
Ref Doctor
This is used to select the name of the referral doctor. Alternatively, if the admin
needs to enter the doctors’ details, then he/she can enter from master screen.
One can select the doctor’s list by clicking on the dotted button. On clicking
the dotted button, following screen is displayed. From the list displayed on
screen, user can select the doctor’s name by double clicking on the particular
name for the respective patient.
XL-180
User Interface 6-8
Analyst This is used to enter the name of the analyst. Alternatively, if the admin needs
to enter the analysts’ details, then he/she can enter from master screen. One
can select the analyst’s list by clicking on the dotted button. On clicking the
dotted button, following screen is displayed. From the list displayed on screen,
user can select the analyst’s name by double clicking on the particular name
for the respective patient.
Parameters Description
Patient Name Enter patient name in the field using the keyboard. A maximum of 30
characters can be fed in this field. Alternatively, patient can be selected
using the dotted button placed next to the Patient Name. Also, if the user
desires to use the same patient with different sample ID, then he/she can
double click on the dotted button and select the patient name for a
different Sample ID. Hence one Patient can have multiple Sample IDs.
Category This field is used to identify the sex of the patient. Select as Male /
Female / Child / Other.
XL-180
6-9 User Interface
Age Enter the numerical age of the patient (in three digits maximum). Choose
age in Days/Months/Years using the pull down option. The patient age is
used to issue H and L flag for the corresponding age range as mentioned
in the Test Parameters (see section 7.2 Test Parameters). If age of a
patient is not fed, default normal values are used to issue H and L flags.
Address 50 alphanumeric characters are allowed in this field where one can enter
the address of the patient.
Patient Tel No This field is used to enter the contact number of the patient.
Patient Remarks Remarks about patient can be fed here using up to 50 alphanumeric
characters. Previously fed remarks can be selected by pull-down options.
These remarks are printed in the patient report
Height This field is used to enter the height of the patient (in meters).
Weight This field is used to enter the weight of the patient (in kilograms).
Body Mass Index (BMI) for the patient is calculated automatically that is
used for Creatinine Clearance calculation. BMI is calculated by the
following formula:
BMI = (Weight)/(Height)2
Urine vol(ml/24 hrs) Use this field to define the volume of urine collected from a patient in 24-
hour duration. This is an optional parameter and is used in the calculation
item of Creatinine Clearance. This field can be ignored if user does not
want to use Creatinine Clearance calculation item.
If user wants to use Creatinine Clearance calculation item, entry in this
field is necessary and the user should feed the urine volume (in ml)
collected in 24 hours in this field
Clear Schedule is used to clear the patient samples scheduled on the SRGT tray or from the work
list.
There are two options to get this, Clear Schedule and Positions or Delete Sample. Using
these options, the user can either clear the entire patient schedule programmed along with the
XL-180
User Interface 6-10
positions or delete the patients using the From Position and To Position option.
Clear Schedules and Positions: The program deletes the test requests scheduled for analysis
and the positions for the Sample IDs on selected positions on clicking OK button. The samples
and patients are not deleted.
Delete Sample: The program deletes the samples on the selected positions along with
demographics and the test requests scheduled. Option to recalculate test results is not available
for deleted patient samples.
The Work List button available on the Patient Entry screen displays the list of requested test for a
particular group number.
The work list for any group can be viewed by selecting the following options All, Patients,
Calibrations or Controls.
On selecting ‘Patients’ option, only patient samples are displayed in the work list. On selecting
‘Calibration’, work list will display Blank, Standards and Calibrators programmed.
On selecting ‘Controls’, work list will display controls programmed in the respective group. The
test from the Work List screen can be masked using Mask Test(s) option.
Use this option to copy the same tests and calculated items across patient samples.
Enter the patient and sample details and schedule the tests/calculated items. Then click on the
Copy Test(s) button. Upon clicking this button, enter From and To sample positions, to which
XL-180
6-11 User Interface
you desire to copy test schedule. The entire range of sample positions would be assigned the
same tests and calculation items.
When the option Generate Sample ID is checked, an incremental sequential series of unique
Sample IDs will be generated for the range of selected positions.
While copying ISE tests from Serum Sample to Urine sample, Lithium test will be excluded; as
Lithium is not performed for Urine Samples. Following screen illustrates an example to copy
test(s) of source Sample ID (selected in Patient Entry screen) to Sample positions 2 to 6 of Group
1, along with generation of Sample ID (unique sequential series).
Upon scheduling the tests, the user can click on the Mask Tests button to mask the tests
temporarily which should not be run immediately but can be run in the middle of the run. The
selected tests for the selected Sample ID will be masked.
To mask the Test(s) for the (multiple) Samples. Tick the Mask Tests check box in the Patient
Entry > Work List screen and select the required test(s). This feature is useful if the reagent for
the tests are not available but would be made available during the middle of the run. In these
cases, the user can mask the tests and keep them on hold.
Once the reagents are available, then the user can unmask the selected tests from Status
Monitor > Work List screen.
XL-180
User Interface 6-12
To mask the Test(s) for the entire multiple samples, select the option Mask Test(s) in the Patient
Entry > Work List screen.
On selecting, the following pop up message will be displayed on the screen. Select the required
tests and click OK.
XL-180
6-13 User Interface
This button is displayed on the Patient Entry screen only when the Host
Connection check-box is selected in Settings > System Parameters screen.
The Download Sample button is used to download the sample details (like patient name, age,
gender, sample type, etc) along with the test details; from the LIS for the selected samples;
irrespective of whether they are barcoded or non-barcoded samples, that are placed on analyzer’s
Sample Tray.
Before downloading the sample details from the LIS, make sure that you should have the following
necessary pre-requisites:
The option Host Connection in Settings > System Parameters screen should be selected.
The Host Setting screen is always enabled to view the settings.
1. Place the barcoded or non barcoded sample on the analyzer’s sample tray.
2. Go to Patient Entry screen, and define required details for the added samples.
It will display a window containing all registered sample IDs with check-box option to select.
XL-180
User Interface 6-14
4. Now, select the required sample IDs details to be downloaded from the LIS and click
Download.
On clicking, the sample details will be downloaded from the LIS to barcoded samples and the details
are displayed in the Patient Entry screen.
If the communication between Host and LIS is not established then it should pop
up message to check connection in Host Settings screen.
6.3.1.8 CEC
This section tell you how to schedule, clear schedule and edit CEC for a patient.
CEC option is available in the calculation item list. When you click on this, following screen is
displayed.
XL-180
6-15 User Interface
When Patient Name is selected then sample Id’s will be displayed in the list for that patient only, and
if the patient name is not selected, then the entire list of sample Id’s will be displayed in the list
irrespective of the patient name. (Patient Name selection is optional). Patient ID is automatically
displayed on selecting the patient name.
Schedule CEC
Edit
For CEC (default calculation item), user can choose any of the photometric test
whose name start with CRE. (e,g. CRE, CREA, CREAT, CRENZ)
2. Click on Show Sample ID button to view and select the sample id from the list.
3. Select the Sample ID – Serum / Plasma from the list of sample id with sample type as
serum / plasma for the patient selected or all sample id’s.
4. Select the Sample ID – Urine from the list of sample id with sample type as urine for the
patient selected or all sample id’s.
XL-180
User Interface 6-16
On clicking, the Height, Weight and Urine Volume will be updated for both the Sample ID
and the message will be displayed indicating that CEC is schedule successfully.
This section tell you how to clear CEC schedule for a patient.
2. Click on Show Sample ID button to view and select the sample id from the list.
3. Select the Sample ID – Serum / Plasma from the list of sample id with sample type as
serum / plasma for the patient selected or all sample id’s.
4. Sample ID – Urine will automatically be displayed according to the Serum / Plasma Sample
Id selection.
7. Urine Volume (ml/24 hrs) will be displayed according to the Patient Name / Sample Id
selection.
8. Click on Delete button. Message will be displayed indicating that CEC schedule is cleared
successfully.
6.3.1.8.3 Edit
2. Click on Show Sample ID button to view and select the sample id from the list.
3. Select the Sample ID – Serum / Plasma from the list of sample id with sample type as
serum / plasma for the patient selected or all sample id’s.
4. Sample ID – Urine will automatically be displayed according to the Serum / Plasma Sample
Id selection.
5. Height will be displayed according to the Patient Name / Sample Id selection. The height
displayed can be changed.
6. Weight will be displayed according to the Patient Name / Sample Id selection. The weight
displayed can be changed.
7. Urine Volume (ml/24 hrs) will be displayed according to the Patient Name / Sample Id
selection. The Urine Volume displayed can be changed.
XL-180
6-17 User Interface
8. Click on SAVE button. Message will be displayed indicating that CEC schedule is cleared
successfully.
Every default tests will displays a revision number on top right of the screen
for identification. Using this, user can match the revision number with the
one printed on the kit insert provided in reagent pack to ensure correct
parameters are used with the pack of measurement.
Test Details
Reference Range
Test Volumes
Copy Test
Initialize tests
XL-180
User Interface 6-18
Parameters Description
Test Enter a short name for the Test, maximum up to 5 characters. This test name is
used to select / display test(s) on all screens. A unique name is required for each
test as this is the identity. Enter the name along with appropriate parameters and
click on SAVE. The test name will appear at the end of the Test panel in the
bottom of the screen.
Report Enter the full name (50 characters maximum) of the test (assay) that will appear
Name in the patient report. For example, one feeds Aspartate Transaminase in this text
box, while AST is entered in Test text box.
Host Name Enter test name, up to 5 characters, assigned in the LIS. This name could be
same or different to the Test Name. This text box will be available only if the Host
Connection is activated from Settings > System Parameters screen.
Special Select this option if any of the tests selected requires special diluent. Special
Diluent diluent must be defined in the consumables and position should be assigned
through Utility screen, if at least one test is selected as special diluent required,
otherwise batch run will not start.
Total Select the total number of reagents used for the test. The drop-down list gives a
Reagents selection of 1 or 2 Reagents for single and dual reagent assays respectively.
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6-19 User Interface
Reagent R1 Upon selecting the Total number of Reagents, the reagent name needs to be
and Reagent selected. This is different from Test Name and the Reagent Name is defined in
R2 Consumables > Reagents screen. The user can select the Reagent Name for that
test. This is the name that appears in the Utility > Reagent Position screen while
viewing / defining the positions of the Reagents placed on SRGT Tray.
More than one test can share the same Reagent Name.
One test can have any number of multiple positions for R1 and R2
respectively
Assay Type
Use this pull-down option to select the assay type among 1POINT, 2POINT,
RATE-A and RATE-B. It is recommended to use:
1 POINT:
The method is used for normal end-point assays using one or two reagents where
the final absorbance is used for concentration calculation. Mean of the
absorbance’s recorded between M2Start and M2End points are taken and this is
used for the calculation of the sample results.
2 POINT:
This method is used for end-point analysis when a sample or reagent blank is
necessary. In this assay type, the initial absorbance (usually measured after
addition of the first reagent) is recorded and subtracted from the final absorbance
(which is usually measured after addition of the second reagent). Necessary
correction factors to correct the difference in mixture volume are taken into
account while subtracting the initial absorbance. The initial absorbance recorded
is the mean of the absorbance’s recorded between M1Start and M1End and this
absorbance is subtracted from the final absorbance, which is the mean of the
absorbance’s recorded between M2Start and M2End. This differential absorbance
is then used for calculation of sample concentration.
XL-180
User Interface 6-20
RATE-A:
This method is used for kinetic/rate assays where the change in absorbance per
minute is used for result calculation. The slope (absorbance change per minute)
is obtained from the absorbance’s recorded between M2Start and M2End using
the least square linear regression method as per the following formula:
.
Where, Ti is the time in minute and Ai is the absorbance, n is the number of
points.
RATE-B:
This method is used for kinetic/rate assays where differential rate is useful. The
initial rate of change in absorbance per minute (usually obtained after addition of
the first reagent) is subtracted from the final rate of change of absorbance per
minute (usually obtained after addition of the second reagent). Necessary
correction factors to correct the difference in mixture volume are taken into
XL-180
6-21 User Interface
account while subtracting the initial rate of change in absorbance per minute. The
initial rate of absorbance change per minute is recorded between M1Start and
M1End using the least square regression method and is subtracted from the rate
of change in absorbance per minute recorded between M2Start and M2End using
the least square regression method explained in the section on RATE-A assay
type.
M1 Start and These assay points are used to select the time points for measurement of initial
M1 End absorbance for 2POINT and RATE-B assay types. This absorbance serves as
reagent or sample blank. This initial absorbance (or absorbance change per
minute) in these assays is subtracted from the final absorbance (or absorbance
change per minute) that is measured between M2Start and M2End points.
M1Start and M1End can have values from 1 to 34 for 2POINT and RATE-B
assays.
For 2POINT and RATE-B chemistries, M2Start has to be more than or equal to
M1End.
Wavelength- This is used to select appropriate primary and secondary wavelengths for
Primary absorbance measurement. The measurement wavelengths are selected from 8
fixed values provided. In case of bi-chromatic measurement, the final absorbance
is obtained by subtracting the absorbance at the secondary wavelength from that
at the primary wavelength.
The analyzer offers a choice of 8 wavelengths with a narrow bandwidth (<8 nm) for
programming the wavelength. The choices are 340 nm, 405 nm, 505 nm, 546 nm,
578 nm, 600nm, 660 nm, and 700 nm.
Secondary When the methodology specifies bi-chromatic measurement for an assay, user
Wavelength can select a secondary wavelength at which the absorbance to be measured. The
selection is made with the pull-down option provided. The following secondary
wavelengths are available in the analyzer: 340 nm, 405 nm, 505 nm, 546 nm, 578
nm, 600nm, 660 nm, and 700 nm.
If bi-chromatic measurement is not desired, keep the choice as SELECT for the
value of the secondary wavelength.
Control The Control Interval parameter enables the user to define number of samples after
Intervals which the control serum will run automatically. This interval can be selected
between 0 and 1000. For example: Control Interval = 30 means that control serum
will be run after every 30th sample analyzed for that chemistry
Sample Enter the value between 1 to 30 stating the number of repeated sample
XL-180
User Interface 6-22
User can define or can create any number of units in Master >
Unit screen.
Decimal Enter the number of digits to be displayed and print; after the decimal point of the
Places test results (photometric / ISE tests) .
Enter the number of digits between 0 and 5.The rounded-off result value will be
used to apply Reference Range Flag to Patient samples & SD Flag, as applicable
Prozone Specify the minimum limit for the absorbance at the end of an
Limit % immunoturbidimetric reaction as a percentage of the maximum absorbance
observed during the course of a reaction. Prozone limit should be between 0 to
100%. If the percent ratio of the final absorbance (at M2E) with the maximum
absorbance in the time course (up to the point M2E) violated the prozone limit, a
flag P* is issued and result will be declared as NA. If the option Auto Rerun is
selected, the sample is automatically sent for a Decreased volume rerun. If you
want to make sure that the absorbance is increasing monotonically in the time
course, feed a value of 100(%). Enter “0” in this text box, in case the check is not
desired.
Prozone This displays whether the entered value is an upper limit or lower limit. For
Check increasing reaction direction chemistries, it is displayed as “Lower” and for
decreasing reaction direction chemistries; it is displayed as “Upper”.
Technical Define the Linearity Limit of the reagents in terms of concentration.
XL-180
6-23 User Interface
Minimum
For the 1 POINT, 2 POINT, Rate-A and Rate-B chemistries, feed the minimum
and maximum concentrations in the Technical Minimum and Maximum Technical
Limit text boxes respectively.
If Tech Limit Min is violated (Final Result < Technical Limit Minimum value), a flag
“TEC-L” is issued and result will be declared as NA. If the option Auto Rerun is
selected, the sample is automatically sent for an increased volume rerun.
Similarly, if Tech Limit Max is violated, a flag “TEC-H” is issued and result will be
declared as NA. If the option Auto Rerun is selected, the sample is automatically
sent for a decreased volume rerun.
Technical Define the Linearity Limit of the reagents in terms of concentration.
Maximum
Enter a value ranging from -99999.99 to 99999.99 indicative of the maximum
technical limit or linearity limit of the reagent. For end-point chemistries and rate
chemistries, feed the maximum concentration. The concentration entered for Rate
Chemistry will automatically be converted into rate after calibration of that test.
This value will be used for comparing with the slope obtained during patient run.
Samples that violate the programmed technical limit maximum are sent for
Decreased volume rerun. If you do not wish to use technical limit maximum, feed
a zero value.
Curve Type This pull down list is used for defining the calibration curve type for that test.
Reaction This parameter defines the direction of the absorbance change with time for the
Direction reaction mixture. Specify whether the absorbance of the reaction mixture
increases or decreases with time.
React. Abs. Define the absorbance limit of reaction mixture for Serum/Urine samples. Enter
Limit an absorbance limit for reaction mixture, depending on the reaction direction
(Reaction (increasing or decreasing). For rate chemistries, the absorbance limit is that
Absorbance absorbance at which the substrate depletion is detected. The absorbance limit
Limit) entered would be in direct absorbance and not in terms of delta absorbance per
minute. For increasing direction chemistries, enter the maximum allowed final
absorbance before substrate depletion takes place. For decreasing direction
chemistries, enter the minimum allowed final absorbance before substrate
depletion takes place.
If Technical Limits are not entered and if the Reaction Absorbance Limit is
exceeded during the course of reaction then the last point of the measurement
XL-180
User Interface 6-24
interval (i.e. M2E) is automatically shifted to the point where this limit has been
exceeded to avoid sample rerun phenomenon. This new point is automatically
used for calculation of sample concentration.
.
Also, in the Reaction Curve Screen, the new point would be shown using a dotted
line, stated as Extd. M2E indicating that the extension logic has been applied to
calculate the result.
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6-25 User Interface
Correction factor a, should have values between -999.9 and 9999.9 while
correction factor b should have values between -99999.99 and 99999.99.
Reagent Abs Enter the minimum and maximum absorbance values of the reagent.
Min and
Reagent Abs This check is applied for flagging only if RgtAbsMin > 0 for decreasing direction or
Max RgtAbsMax > 0 for increasing direction in Test Parameter.
Compare the ABS received after adding reagent, say A1 (for 1 Reagent
chemistry, ABS after adding R1 & for 2 Reagent chemistry, ABS after adding R2)
with the Rgt ABS value entered in Test Parameter.
Tick this check box to set the auto-rerun for a test with appropriate dilution of sample.
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Use SET AUTO RERUN button to set the auto rerun for multiple tests.
Click on the desired option to choose Selective test or All test(s) for auto rerun.
If Selective is selected then user can select test(s) from the list below for setting auto-rerun by
clicking on the boxes in the front of tests. Then click on OK button.
If All test(s) is selected then automatically all the tests in the list below will be selected for auto
rerun. Click on OK button to save and apply settings. Click on CLEAR button will close the window
without saving changes.
Before selecting the tests for auto rerun, specify the increase and decrease sample volumes for the
test in Test Volumes screen. See Test Volumes for more details.
When auto rerun for test is selected, patient sample will automatically re-run (performed again) on
occurrence of specific flags to the result.
You can set the flags for rerun in Rerun Flags screen, as per your requirement.
Auto Rerun is also selected from PRE-RUN options in Status Monitor screen
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This button is used to copy the test parameters from one test to another.
To copy, select the required test from the Test panel, and click COPY TEST. Enter a new test name
and click OK. The new test name will be displayed in the Test panel.
Newly copied test will be displayed in Setting > Test Sequence > TEST PROCESS SEQUENCE
based on Open / Closed reagent type.
On copying the test, if the source test is having the Cal* flag, then the copied
test will also have Cal* flag till it is calibrated.
Upload Test
Using UPLOAD TEST button, the parameters of the selected test gets uploaded.
Default tests parameters are updated through ENC file format only.
Before uploading parameters for a Default test, make sure that respective test is available in the
tests panel. In case, if test is not available or deleted, it will automatically add the respective
parameter after user confirmation. See the following figure:
Whenever the parameters of the default test are updated using UPLOAD TEST, the revision
number will also get updated.
While updating default Test Parameter from Upload Test Option, if Curve Type changes from
Linear to Non-Linear or vice versa, then Application will ask for user confirmation.
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Upload Test for default parameters, overwrites the weak parameters (user editable parameters)
and Reference Ranges only after user’s confirmation.
After uploading the test parameters, make sure that correct parameters got
updated by verifying version number in the test parameter (which should
match with the version number of kit insert).
The UPLOAD TEST option will be disabled for the ISE tests
Download Test
Using DOWNLOAD TEST button, the parameters of the selected test are stored in a xml file and
saved in the C:\MultiXLLOG\DOWNLOAD PARAMETERS. A reagent distributor/manufacturer
may enter a new test from test parameter screen, download parameters and send the xml file to
distribute parameters to their customers.
The DOWNLOAD TEST option will be disabled for the ISE tests.
This button is used to initialize the test parameters from existing ones to default settings. The tests
with similar test names are replaced from default ones and the newly added tests are retained as it
is. To initialize test parameters, click on INITIALIZE TEST(S) button, select the test(s) to be
initialized and confirm by clicking on OK button.
For ISE tests, on selecting any one of the tests from Na / K/ Cl / Li will select all the tests (Na / K /
Cl / Li).
Some test chemistries requires special diluents for example HbA1c. Select this option, if any of the
selected tests requires special diluent.
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Special diluent is defined through the Consumables screen and its position assigned through Utility >
Reagent Positions screen.
When Special Diluent/Reagent is not available on-board, user can either stop run or mask test and
proceed run.
Follow the step to use Test-specific Special Diluent for an Open / Closed Channel Photometric Test:
4) Define different test-specific diluents to be used during run and click Save.
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8) Also by using Special Diluent >Click ,user can edit special diluent for test as shown in
below screen.
9) Select the test and Click EDIT. Select the Special Diluent Name from drop down list as show
below
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If Special Diluent is selected in Test Parameter >Test Details for the particular
test, and test specific special diluent is not defined (**Any** is selected) then any
consumable available under special diluent category will be utilized during
RUN.
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It displays the sample and reagent volumes for a test along with the sample type. It also includes an
option of copying the sample volumes if the SERUM, URINE, CSF, WHOLE BLOOD, PLASMA and
OTHER sample types share the same volumes as Serum sample type.
For performing auto rerun for a sample, first you need to specify the required increase and decrease
sample volumes along with dilution ratio.
Parameters Description
Normal Specify normal (or default) sample volumes depending on the selection of sample
type.
Increase Specify sample volume (higher than normal) to carry out an automatic rerun of the
sample in case of a hyperactive sample or when the Sample is requested as
increase in the Patient Entry screen.
Decrease Specify sample volume (lower than normal) to carry out an automatic rerun of the
sample in case of a low reactive sample or when the Sample is requested as
decrease in the Patient Entry screen.
Standard
Specify volume to be used for calibration that is Blank, Standard and Calibrators.
Volume
Dilution
Specify the dilution ratio for normal, increase and decrease sample volume.
Ratio
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Parameters Description
RGT-1 Volume Specify volume of reagent to be aspirated for Reagent 1.
RGT-2 Volume Specify volume of reagent to be aspirated for Reagent 2.
R1 Stirrer Speed The mixture of reagent and sample are mixed by stirrer at three fixed speed
that is Low, Medium and High, as appropriate.
R2 Stirrer Speed The mixture of reagent and sample are mixed by stirrer at three fixed speed
that is Low, Medium and High, as appropriate.
Note: This parameter will not be displayed for single reagent test.
Copy Volume button is used to copy the volumes from current sample type to other sample type(s)
of the selected test.
View Volume button is used to view the volumes programmed as per the different sample types.
Use HIDE VOLUMES button to go to previous screen.
Tick this option, if you want to pre-dilute standard/calibrators using normal dilution ratio of Sample. It
is available for photometric tests only.
It is also used to copy the reference ranges of one sample type to different sample types for the
selected test.
Depending on the reference range selected the Normal Ranges for Male, Female, Child, or Other
would be used accordingly to generate the H and L flags.
You can define reference range through Master menu. See section To add reference range for more
details.
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Parameter Description
s
It displays the test as selected from the Tests panel.
Test
It displays the sample type as selected from the list of available Sample Types.
Sample
Type
This drop down list contains different age groups, in addition to DEFAULT. Select
Reference
appropriate age group to define the normal range and panic limits. To add a new age
Range
group, see section To add reference range for more details.
This drop-down list is used to select the category (gender). The available options are:
Category
Default, Male, Female, Child, and Other.
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Define the expected values or normal range for Serum/Urine/Other samples being
Normal
assayed. These limits are used to issue H or L flag, which indicate a higher
(Lower
concentration than normal or lower concentration than normal respectively.
Limit and
Normal Normal range values for both Male and Female subjects can be specified for two
Upper different age groups. Additionally, default normal range values can also be defined for
Limit) Male, Female, Child and Other subjects.
The default normal range is used if the age of the patient is not known.
Use this to enter the expected values range for different sample types for different
assays.
Panic Define the minimum and maximum concentration limits for results which are unusual
(Lower and enough, requiring special review by the technician. These values are the upper and
Upper lower panic value limits for specified tests.
Limits)
When the sample result violates the Panic Limit Minimum or Maximum, a flag PANH
or PANL is issued with the result respectively. It is recommended to recheck such
result by repeating the test before reporting.
An automatic rerun of the patient sample, to repeat the test due to Panic Limit
violation, will be performed if:
Auto rerun option is selected for the respective test in Test Details screen
Rerun flag is selected for PANH and PANL in Rerun Flags screen
Auto rerun option is selected from PRE-RUN Options in Status Monitor screen
When PANH or PANL flag is issued to a result of patient sample, the "same" (re)run
will be performed. A same rerun means using the sample volume same as it was
programmed in the first determination.
For example, if the sample was programmed for a normal volume run then the rerun
too will be performed using normal sample volume.Similarly, if the sample was
programmed for Decreased or Increased volume run, then the rerun will be performed
using a Decreased or Increased volumes respectively. The rerun result is flagged “#” to
indicate a rerun.
This button is used to copy the reference ranges from current sample type to other sample
types. Multiple sample types can also be selected.
This button is used to view the reference ranges programmed as per the different sample types.
Use HIDE VOLUMES button to go to previous screen.
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6.3.3 Profiles/Calc
Profiles/Calc is used to perform the following operations:
To create profile
6.3.3.1 Profiles
Profiles screen is used to create test profile. Profile is a predefined group of tests.
Once created, they are used for selection through a single click, during the patient entry details in
the Patient Entry. One or more profiles can be selected for a patient at the same time.
If these calculation items are selected in the Patient Entry screen, then the test(s) required to
calculate the value are selected (scheduled) automatically. The calculated items are printed along
with the test result in the Patient Report printout.
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Parameters Description
Calculated Define the name of the calculated item, up to 5 characters. This name will be shown
Item in a separate grid in Patient Entry screen.
Report Enter the full name of the calculated item (i.e., A/G ratio). This name is printed on the
Name patient report.
Formula The user can select the desired calculation formula from the drop down list. If new
formula is required, you can create your own formula using Calculation Formula
screen.
Unit Select the unit to be printed along with the calculation Item.
Host Name Enter the name of the calculated item, as defined in LIS (for host communication).
This text box is visible only if Host connection is activated from System Parameters
screen.
Decimal
Enter the number of decimal places for the calculated item.
Places
Once, the formula is selected, the user can select the tests associated with the
calculation item. Additionally, the user can also use another calculation item (nested
calculation items) for defining a new calculation item.
The user can select the normal ranges or panic limits (if desired) for the calculation
item depending on the sample type selected. Normal Range options are available for
Male, Female, Child or Other types.
CEC Calculation item is present by default. For this calculation item, only the Report
Name, Unit, Decimal Places and Normal Ranges can be modified. Test A can also be
selected and Test B will be displayed same as Test A.
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If CRE is deleted from the test parameters screen, then CEC is not visible in
calculated items.
When CRE is again initialized through the test parameter screen then a
Activate CEC button is displayed on the Calculated items screen. On clicking,
CEC is again visible in the Calculated Items.
6.3.4 QC/Calibration
QC/Calibration is used to perform the following operations:
Scheduling consumables
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Scheduling Standard
Scheduling Calibrator
Scheduling Blank
Scheduling Control
1. Select the group number on which the calibration and QC run needs to be performed using
Group drop-down list.
2. Select a desired position from the Position drop-down list. This drop-down will also display
the last scheduled consumable name at respective position. This consumable name is
retained for a position till a patient sample is defined on that position.
3. Select appropriate container from the Container Type drop down list.
4. Select consumable type as 'Standards' from the Consumable Type drop down list.
6. Select the required Lot No. of the selected consumable. The last defined lot number appears
as selected, by default.
On selecting the lot number, a grid with the list of tests for the selected consumable appears
on the right side of the screen, where in option of auto dilution and dilution ratio can be
selected for non-linear chemistries.
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Depending on the concentration and the DilRatio (dilution ratio) selected for the test, the
number of serial dilutions possible will be displayed in another grid as shown in the following
figure.
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User Interface 6-42
If the dilution ratio is not selected then default dilution ratio will be applied
to the test. The default dilution ratio is 2.
8. Click OK.
On clicking, the details will be added in the required position as shown in the following figure.
.
Auto-dilution is possible for non-linear curves.
Auto-dilution is not possible for the curve types K-factor and Linear. The
gray background color in the column AutoDil indicates that auto-dilution is
not possible for the respective test.
If Auto dilution is scheduled for a test then Normal Dilution Ratio cannot be
applied for that test. In this case, you have to clear the auto dilution
schedule.
The MultiXL will prompt a message if the required Blank and Standards /
Calibrators are not scheduled.
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While performing the Blank, Standards, Calibrators and Controls that are scheduled, the
sample and reagent volumes defined (in Test Parameter > Test Volume) for Sample Type
Serum is used. This is indicated by Serum in the column Sample Type.
To clear the schedule CLEAR POSITIONS button can be clicked. On clicking, following
screen is displayed to either clear selected positions or all the positions.
Clear position button does not clear the sample positions. Only scheduled Blank,
Standards, Calibrators and Controls will be cleared.
1. Select the group number on which the calibration and QC run needs to be performed using
Group drop-down list.
2. Select a desired position from the Position drop-down list. This drop-down will also display
the last scheduled consumable name at respective position. This consumable name is
retained for a position till a patient sample is defined on that position.
3. Select appropriate container from the Container Type drop down list.
4. Select appropriate consumable type, Calibrator, from the Consumable Type drop down list.
6. Select the required Lot No of the selected consumable name. The last defined lot number
appears as selected, by default.
7. On selecting the lot number, a grid with the list of tests for the selected consumable appears
on the right side of the screen, where in option of auto dilution and dilution ratio can be
selected for non-linear chemistries. See figure below.
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8. Select the required test (tick manually against each required test or click on Profile to select
multiple tests under the profile), Select auto dilution and dilution ratio, as applicable and then
click OK.
You can create your own profile through Profiles /Calc > Profiles.
Following figure shows that tests are selected through available profile ‘LIPID’.
9. On clicking OK, the tests will be added in the selected positions as shown in the following
figure.
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6-45 User Interface
10.Click on SCHEDULE.
The MultiXL will prompt a message if the required Blank and Standards/
Calibrators are not scheduled.
1. Select the group number on which the calibration and QC run needs to be performed using
Group drop-down list.
2. Select a desired position. User can view the occupied sample positions in the grid placed on
the lower half of the screen.
3. Select the appropriate container type from the Container Type drop-down list.
6. Select the required Lot No of the selected consumable name. The last defined lot number
appears as selected, by default.
On selecting the lot number, grid on the right side of the screen displays the available tests
for the selected consumable for running the QC and test Profiles grid with available profiles.
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Tests
Selective
Curve Type
Selective: Tick this check-box to schedule Selective Calibration (perform only blank to
derive the calibration curve) for the test.
The check-box with Gray color in the Selective column indicates that the
test may not be Calibrated or Already Scheduled or Unsuccessfully
Calibrated. In such case, selective calibration option is not available.
7. Select the required test (tick manually against each required test or click on Profile to select
multiple tests under the profile), click on OK.
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On clicking, the test(s) will be added in the selected positions as shown in the following
figure.
Test(s) scheduled with Selective Calibration are marked with Asterisk (*)
symbol under column Pos.
The MultiXL will prompt a message if the required Blank and Standards/
Calibrators are not scheduled.
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1. Select the group number on which the calibration and QC run needs to be performed using
Group drop-down list.
2. Select a desired position. If the position is occupied, then the user can view it in the grid
placed on the bottom side of the screen. This drop-down will also display the last scheduled
consumable name at respective position. This consumable name is retained for a position till a
patient sample is defined on that position.
3. Select appropriate container type from the Container Type drop-down list.
6. Select the required Lot No of the selected consumable name. The last defined lot number
appears as selected, by default.
On selecting the lot number, grid on the right side of the screen displays the available tests
for the selected consumable for running the QC and test Profiles grid with available profiles.
Sample type (Serum/Urine) will get displayed accordingly in sample type with respect to
selected control for the test See figure below See figure below.
7. Select the required test (tick manually against each required test or click on Profile to select
multiple tests under the profile), and then click on the OK.
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On clicking, the details will be added in the required positions as shown in the following
figure.
8. Click on SCHEDULE.
If a position was used during earlier calibration run, then consumable name
is also displayed along with the position number in ‘Position’ drop down list,
till the new patient sample is defined on that position. See figure as shown
below.
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6.3.4.2 Calibration
Calibration screen allows to view calibration curve and to perform curve related operations. Lot
number and concentration for that test are defined in the Consumables screen.
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Test Revision (if available) will be displayed on the screen in red color as seen in
the above image.
This Revision shall be printed on the Calibration Report as well, as shown below;
After the calibration run is completed, absorbance values obtained by the analyzer are updated in
the Calibration screen along with the K-Factor. The date and time of calibration is also updated.
One of the last five calibration curves can also be selected for use in result calculations.
For using the calibration on the screen, use Set Latest Calibration button. In order to view the
calibration details for a test in use, the user needs to select the test from the grid.
For any 2-Point chemistry, if the concentration obtained by the calibration curve
is negative (below zero), then the output test result will be in multiple of 0.1 (or
zero), based on decimal places set for the test.
To print the calibration table along with the calibration graph, click on PRINT button.
If there has been some error during calibration (like reagent absent or
calibrator absent), the calibration data for which reagent, blank and calibrator
was present is updated. However, Unsuccessful Calibration message will be
displayed.
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Parameters Description
Test It displays the test name.
Last
Calibration It displays the date on which the calibration of the test was performed lastly.
Date
Curve Type It shows the curve type selected for the test in Test Parameters > Test Details
screen.
Calib Expiry It allows the user to enter the Calibration Expiry Limit for that test in days. This limit
Limit is a decremented counter that commences after calibration for that test is done. The
Test, for which the calibration is expired, is highlighted with Pink color in the Patient
Entry screen.
Acceptable Use this text box to enter the acceptable limit allowable between 2 calibrations. The
Limit % user can feed any value between 1% to 10% and is expressed in terms of
percentage.
When the value is set to 0 (zero), the comparison of the factors is not done. The
comparison is made on basis of the factor obtained. The new factor obtained is
compared with the old one and based on the acceptance limit entered; the new
calibration details are updated. If the value falls outside the acceptable limits, then
the old calibration details are kept and the new details are updated with message
Factor out of Range. This text box is applicable only for Linear curve types.
Calibration It displays the date on which the calibration, currently displayed on screen, for that
Date test was performed. The display changes if previous calibration is selected.
K-Factor This parameter will be displayed only when the curve type for the test is selected as
K-factor in Test Parameter > Test Details. It is used to enter the known factor for the
required test. The value should be non-zero number between -99999.99 to 99999.99.
R1/R2 Lot No It displays the Reagent Lot Number used for calibrating that test. If the test has only
one reagent, then only R1 Lot No will be displayed.
Parameters Description
Pos It displays the Calibrator, Standard or Blank position; till the position is not utilized
for scheduling any other sample
Consumable It displays the consumable name (Blank, Standard, or Calibrator) used for
calibrating that test
Conc It displays the concentration of the blank or the calibrator used
Abs This column indicates the absorbance values that are automatically obtained by the
analyzer after the calibration is carried out.
Lot No. It displays the Lot Number of the consumable used for Calibration of that test.
Factor It displays the Calibration Factor obtained for the selected test
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Set Latest Calibration: Use Prev and Next buttons on the screen to view the previous or next
calibration record, and then select any one calibration which should be used for patient result
calculation. Click on Set Latest Calibration button to set the selected calibration and use the same
for calculating results.
Copy Calibration: This button is used to manually copy the calibration details across test(s) with
same assay type and specific curve type (either both liner either both linear or both non-linear
requiring same number of calibrators); sharing the same Reagents.
Selective Calibration: Selective calibration, also known as One point to Multipoint Calibration or
Normalization of Calibration Curve is used when a user wants to use only a reagent blank for
calibration. It is applicable for all curves except K-factor. The user can schedule and perform this type
of calibration for individual chemistries.
On clicking this button, two options are available under Calibration Type for the selected test:
Full: This option is the default selection through which you can schedules the entire
calibration set again.
Selective: This option is used to select blank available and then it uses the slope
method to correct the other factors.
Repeat Calibrators: This button is displayed for the non-linear test on which the last calibration is
performed within last 24 hours. Using this button, errors of point in a non-linear calibration graph, can
be corrected by repeating the single/multiple calibrators, instead of repeating the entire calibration.
For example, see the following figure.
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User Interface 6-54
On clicking this button, list of calibrators processed during calibration will be displayed.
Select the appropriate calibrator(s) to be repeated by ticking the check-box at the respective row and
click SCHEDULE button. One or multiple calibrator(s) used to derive the curve can be selected to
repeat.
Schedule of such calibrators will be displayed with Asterisk (*) symbol next to test in QC/Calibration
> Schedule QC/Calibration screen. Asterisk (*) symbol indicates selective calibration with Blank/
Repeat calibrator.
This button is not available for the test whose curve type is linear or k-factor and
for non linear test more than 24 hours old.
Repeat Calibrators: This button is displayed for the non-linear test on which the last calibration is
performed within last 24 hours. Using this button, errors of point in a non-linear calibration graph, can
be corrected by repeating the single/multiple calibrators, instead of repeating the entire calibration.
For example, see the following figure.
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This button is not available for the test whose curve type is linear or k-factor and
for non linear test more than 24 hours old.
6.3.4.3 QC Data
The QC (Quality Control) screen is used for day-to-day monitoring of the performance of the analyzer.
Accuracy of the analysis (i.e. whether the values obtained are correct)
Precision (i.e. the reproducibility – whether the same values are obtained when the sample is
analyzed repeatedly)
The QC Data is useful for viewing the QC Results in Graphical format. QC Rules implementation has
been on QC Results in the QC Data and is marked with a respective color to indicate which rule has
been violated for that test.
Enter remarks
The user should either rerun the controls again or recalibrate the test and run the controls.
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To open the screen, go to QC/Calibration > QC Data screen. The following screen is displayed as
shown below:
1. Select Date From and Date To. The user can select the same date for viewing the daily QC or
select a range for viewing the Monthly QC.
2. To select the test, click on dotted button near the Test text-box, a small window will open up
through which the test can be selected.
3. Select the control level using dotted button near Control text-box and hence control name for
which results and graph should be displayed. If the selected Date From and Date To are
same, all the control results can be seen. But if the user has selected Date From and Date To
different, then only one control results can be seen at a time.
4. Lot number for a control can be selected from the Lot No. drop-down list.
5. Once the above selection is done, click on DATA button to view the results for the selection in
the result grids.
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6. Batch No. will be displayed for selection, if the date range selected is same. See the following
figure.
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User Interface 6-58
If the date range selected is from “x” period to “y” period (see Figure A), then,
If a single date is selected (see Figure B ), then the X-bar Calculation grid signifies the
following:
Level: Displays the test control levels.
N: Number of replicates the control is run during that day.
Avg: Average of the test result values on that day.
SD: Standard Deviation for that day
%CV: Coefficient of Variation calculated from Mean and SD.
R: Difference between maximum and minimum result (if replicates are done)
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In the QC results, Result column will be highlighted in different colors, if any of the default
QC rules stated below is violated. See the following figure for example.
The above six rules are given different colors to highlight the result or the point on the graph when the
corresponding rule is violated. To see the QC rules, just place the pointer over any of the item, a pop
message will be displayed with description.
The user needs to check the control result after the control run is completed and hence take
corrective action whether to continue with patient samples or not. Or else perform calibration again
and re-run the controls to check if the results are proper.
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Click on the remark icon to enter user remarks, such as, reasons or corrective action taken for
outlier QC results (if required). See the figure as shown below.
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Excluding QC points permanently and view proposed graph with lab mean
QC points can be excluded by using Exclude QC Results and Exclude and Apply Lab Mean, as
per user requirement.
To do this, select the required QC points to be excluded, and click on the button, as appropriate.
: This button is used to view the data after excluding the selected
QC results. After confirmation it will exclude user selected QC points permanently.
: This button is used to see the preview of graph with new proposed
lab mean excluding user selected QC points.
In the graph, small rounded circles indicate excluded QC points. See the following
example.
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User Interface 6-62
Once lab mean is calculated for the selected control results, it can not
be recalculated. Those results are disabled and indicated with gray
background.
When the lab mean is applied, the new lab mean will be displayed on top right of the
screen with date on which it is applied. See the following figure.
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Use GRAPH button to view graph with new lab mean or manufacturer mean, as
appropriate.
EXPORT: User can click on EXPORT button to export the data to an excel sheet.
For Twin Plot, two levels of control samples with different lot numbers are required. Period (date
range) and Test name needs to be selected before viewing the twin plot.
2. Select Date From and Date To: The user can select the same date for viewing the daily
graph or select a range for viewing the monthly graph.
3. To select test, click on dotted button near the Test text box, a small window will open up
through which the test can be selected.
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4. Select Control for X and also for Y and then click on Show Lot.
5. Select Lot No. for that Control X and also for Y from the list displayed.
e. Mean – Mean of Daily averages if date range is selected Or Mean of all the replicates for
the single date selected.
h. Range - Range of Daily averages if date range is selected Or Range of all the replicates for
the single date selected.
7. Once the above selection is done, click on DATA button to view the results for both the
controls selected.
8. Click on GRAPH to view the graph for both the controls selected. The daily averages for
Control Y are plotted (on the Y-axis) against the daily averages for Control X (on the X-axis).
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9. Uncheck the Show Date check box, if you do not want to display the date on the marked
points.
6.3.4.5 QC Graph
This screen is used to view control data and graph for two different controls. To view the control data,
select the required date range and other details, and then click DATA.
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6.3.5 Consumables
Consumables screen is used to define various consumables such as Reagents, Blank, Calibrators,
Controls, Diluent and Wash, including their name along with their respective lot numbers,
reconstituted dates, concentration and on-board stability of the test are defined in the same screen.
Also, it is used to upload and download consumables. See section Upload and Download for more
details.
Defining Reagents
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4. Enter the appropriate Reagent name, Reagent Code, and Reagent Type.
In the closed system, user is allowed to define or add reagent code only in
the permitted range, otherwise system will prompt a message.
On saving the details, the reagent will be added in the list of reagents as shown in the
following figure.
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6. Double click on the Reagent name from the list of reagents. The selected reagent will be
displayed. See the following figure:
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9. Now enter the manufacturer name from the manufacturer drop-down list. See section
Manufacturer for adding manufacturer name in the list.
11.Enter the expiry date of the reagent in the Expiry Date list.
12.Enter the on-board stability and unit in Onboard Stability text-box and Unit drop down list.
13.Select the Reagent Type check-boxes to be used, as required. The Reagent Type check-
boxes will be pre-selected, if it is already defined while entering the details for new reagent.
14.Once the above details are entered, click on SAVE to save these details.
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4. Click EDIT.
6. After editing the details and click SAVE. The details will be saved.
7. Following table gives a brief explanation on the different fields in the grid.
Stock Over Check this Stock Over box when the stock of the consumable lot is
completely utilized.
Lots marked as Stock Over will not appear in the Lot Selection List -
While defining Reagent Positions in the Utility > Reagent
Position screen
While scheduling Calibration and Controls from QC/
Calibration > Schedule QC / Calibration screen.
Note: In case, Stock Over is not ticked for a Lot; then the Lot will be
excluded from the selection list after its expiry date.
This check-box is available only in Edit mode and not while adding a
Lot.
Lot No Enter the lot number of the reagent.
Lot Status Lot status as Active or Inactive is displayed based on the Expiry Date
defined for the Lot. Expired Lot is displayed as Inactive.
Expiry Date Select the expiry date of the Reagent lot.
On-board Stability Enter the On-board shelf life of the reagent.
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Reagent Type It is used for selecting whether the Lot No selected is common for
R1, R2, and R3. If R2 and R3 are having different lot number, then the
user should save the details for R1 and add new details for R2 and
R3.
Lot details can be edited directly by double-clicking on the required lot from the
main Consumable Screen.
Defining Blank
2. Click on the dotted button next to Consumable name. This will open a new window
"Consumable".
3. Enter new name in the Blank text box and select the tests associated with the blank, and then
click on SAVE.
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Once saved, the user can double click on the blank name for which he wants to add lot
details. This will close the window "Consumable" and take to "Consumable" main screen.
One can also leave the screen by clicking on "X" when one do not want to add lot and go
back to Consumable screen.
4. Click ADD from the main screen, the following screen will be displayed.
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5. Select the Manufacturer name. See section Add Manufacturer for more details.
8. On clicking, the blank will be saved and displayed on the Consumable screen, when the
Blank is selected.
Defining Standard
2. Click on the dotted button next to Consumable name. This will open a new window
"Consumable".
3. Enter new name in the Standard text box and select the tests associated with the standard,
and then click on SAVE.
Once saved, the user can double click on the standard name for which he wants to add lot
details. This will close the window "Consumable" and take to Consumable screen. One can
also leave the screen by clicking on "X" when one do not want to add lot and go back to
"Consumable" main screen
4. Click ADD from the main screen, the following screen will be displayed.
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5. Select the Manufacturer name. See section Add Manufacturer for more details.
10.On clicking, the blank will be saved and displayed on the Consumable screen, when the
Standard is selected.
Defining Calibrators
2. Click on the dotted button next to Consumable name. This will open a new window
"Consumable".
3. Enter new name in the Calibrator text box and select the tests associated with that calibrator,
and then click on SAVE.
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Once saved, the user can double click on the calibrator name for which he wants to add lot
details. This will close the window "Consumable" and take to Consumable screen. One can
also leave the screen by clicking on "X" when one do not want to add lot and go back to
"Consumable" main screen.
4. Click ADD from the main screen, the following screen will be displayed.
5. Select the Manufacturer name. See section Add Manufacturer for more details.
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10.On clicking, the calibrator will be saved and displayed on the Consumable screen, when
Calibrator is selecetd.
Defining Controls
2. Click on the dotted button next to Consumable name. This will open a new window
"Consumable".
3. Enter new name in the Control text box, and select the control type from Type drop down list
and select the Level from the available options (Low, Normal, High, and Very High).
4. Select the tests associated with the control, and then click on SAVE.
Once saved, the user can double click on the control name for which he wants to add lot
details. This will close the window "Consumable" and take to Consumable screen. One can
also leave the screen by clicking on "X" when one do not want to add lot and go back to
"Consumable" main screen
4. Click ADD from the main screen, the following screen will be displayed.
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5. Select the Manufacturer name. See section Add Manufacturer for more details.
8. Enter the mean value for the selected tests in the Mean column.
CV will be automatically calculated, if the Mean and SD are entered for the test. Similarly, SD
will be calculated if Mean and CV are entered.
For example: To calculate CV, select option SD and enter the mean and standard deviation
value for the test in the Mean (manufacturer mean) and SD column. On saving the Control, the
CV is calculated and displayed in the CV column.
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On clicking, the control will be saved and displayed on the Consumable screen, when
Control is selected.
Defining Diluent
1. In the Consumable screen, select the required diluent from the Consumable Type.
2. Click on dotted button and enter the diluent name in Diluent text box in Consumable window.
3. Click SAVE.
Once saved, double click on the diluent name for which he wants to add lot number. This will
close the window "Consumable" and take to Consumable screen.
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5. Select the Manufacturer name. See section Add Manufacturer for more details.
Two separate positions are provided on the instrument for placing the
diluents. Also, diluents and wash can be placed on any position of the
Reagent Tray.
Defining Wash
1. In the Consumable screen, select the required wash from the Consumable Type.
2. Click on dotted button and enter the wash name in Wash Solution text box in Consumable
window.
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3. Click SAVE.
Once saved, double click on the wash name for which he wants to add lot number. This will
close the window "Consumable" and take to Consumable screen.
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5. Select the Manufacturer name. See section Add Manufacturer for more details.
User is not allowed to define system solutions (wash, diluents, etc.) for
reserved reagent codes.
The distributor will generate the files containing consumable details (like Calibrator and Control lot
information along with concentration, target values etc) using DOWNLOAD.
The distributor will send this generated file to the customers along with consumables. The customers
will then upload the given consumable file using UPLOAD.
Downloading Consumables
3. Click DOWNLOAD.
4. On clicking, the Download Consumables window will be displayed which contains the list of
information about all the active (non-expired) lot(s) of consumables as shown in the following
figure.
By default, all consumables will be selected for download. You can select the required
consumables by un-checking the checkbox and then selecting it again as per your
requirement.
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.
At least one consumable lot should be selected to download.
The will generate a XML file containing the consumable information with their respective lot
details (only for active lot). This file is automatically saved in the appropriate location on your
computer. The file name and the location will be displayed on the Indication text box as
shown below:
Uploading Consumable
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2. Now select the required consumable file from the appropriate location, and then click Open.
On clicking, the system will read and verify the data before uploading the file. The consumable
information will be uploaded only if the lot number is not found. This means, if the system
detects that the consumable lot with all or some test(s) already present in the database
(uploaded earlier or defined manually), then it will skip those test(s) without comparing and
changing its respective information (such as Expiry date and Target value(s), and It will upload
only those test(s) along with their respective details that are not available in the database.
.
In case, any error occurs during verification or upload, the error message will be displayed and
data from the file will not get uploaded to database.
Incorrect xml file is selected (other than the one generated using Download option) for
upload, then the following error message will be displayed and upload will not proceed.
The XML file (generated using Download option and received) format is altered, then the
following error message will be displayed “Error in Uploading Consumables” in the
Indication text box, as a result the upload data will be terminated.
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Once the consumables are uploaded, you should verify each of the consumables lot.
From the Consumable screen, select the appropriate consumable (Blank, Standards,
Calibrators or Controls) from the Consumable Type dropdown list, and verify the uploaded
consumables.
The Status Monitor screen has four main options, each of which shows the state of a particular part
of the system.
Sample Tray
Reagent Tray
Reaction Curve
Barcode Scan
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Pre-Run Options
Run-Options
Work List
ISE Pack
Refresh Position
Scan Pack
During Maintenance activity this screen is disabled and can be accessed by the
user only upon its completion.
When starting the batch RUN, if dome is open, then pre run activities will not be
started and error message with alarm beep will be displayed in error display
grid.
There are two levels of dome opening, at Level 1 opening there will be warning
message and alarm whereas at Level 2 opening sampling will be stopped
immediately.
During pre-run activities, if user is on some other screen (e.g. doing patient entry)
then at the completion of pre-run activities, screen may get switched to 'Monitor'
screen for some time to get user's attention but it will automatically come back to
earlier screen so that user can complete remaining activities.
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The Sample Tray screen gives a graphical representation of the occupied samples positions on the
SRGT tray. The tube positions are color-coded so that you can easily check the status of the
samples when they are scheduled for batch run.
When the batch run is started, each samples will go through number of states will be represented in
the following color codes:
Sample tray also shows the current RCT and RGT temperature in the top right position on the
screen. If the RCT and RGT temperature is within range as specified System Parameters, the
temperature is displayed in black color. When the temperature falls out of the range, then it is
displayed in red color.
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After the reagent volume scan the status will be represented in the following color codes:
Color
Status Description
Code
If the level in the reagent bottle is normal, then it is indicated with BLUE
Normal
COLOR
If the level in the reagent bottle is below 20% of the bottle capacity, then
Low
it is indicated with LIGHT YELLOW COLOR
Empty If the reagent bottle is empty, then it is indicated with WHITE COLOR
If the reagent position is free (reagent not defined), then it is indicated
Vacant
with GRAY COLOR
If the samples are allotted in the Flexible Positions, then it is indicated
Allotted
LIGHT RED COLOR
If the reagent position is discarded, then it is indicated with
Discarded
DARK ORANGE COLOR.
If the reagent at a particular position has crossed expiry date,
Expired
then it is indicated with RED COLOR.
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If the diluent is assigned at a position on the reagent tray, then the it is indicated with
GREEN COLOR
If wash solution is assigned at a position on the reagent tray, then it is indicated with
BLUE COLOR
If reagent is assigned at a position on the reagent tray, then it is indicated with
BROWN COLOR
In closed system, volume scan will not be performed for discarded bottles.
Volume Scan button will scan all the reagent bottles present on the SRGT tray and the status will
be displayed graphically on the Reagent Tray screen. After reagent scan, reagent volume details will
be updated in Reagent Position screen.
To do this, click Reaction Curve button and double click on a required test in the Cycle Map grid in
the right-most corner of the screen. On clicking, the Reaction Curve (till “x” cycles) will be displayed.
The pink arrow indicates the measurement points used for calculating the result.
When the run is completed, the final tests result will be displayed in the result grid that is located on
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the right bottom corner of the screen. The final reaction curve will be generated and can be viewed in
Reports > Reaction Curve screen. To view the curve number for the particular test, double click on
the result. On clicking, a small test details box will be displayed, which contains all the information
about the test with curve number.
This option is disabled in closed system as sample tubes and reagent bottles
are always scanned for Barcode.
During this process, all barcoded samples and reagents will be scanned. After scan is over, the
sample details and reagent details will be updated and displayed in the following screens:
Patient Entry
After the scan, the available reagents on the selected tray number will be scanned and the barcode
id will be displayed on the screen. Reagent bottles which are not registered by Scan Pack , then
respective reagent bottle position will be displayed with barcode number along with unknown pack
details as shown in below screen.
On completing sample barcode scan, the tests scheduled on the LIS will be automatically
downloaded and applied to the appropriate samples if the communication between analyzer and
Host.
Barcode scan of the samples will be performed prior to start of the run, if the option Barcode Scan
is selected from the Pre-run Options.
The Barcode Scan button will be disabled if the option Barcode Reader option
is unchecked from the System Parameters screen.
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Auto Rerun
For a particular test of a patient to be sent for rerun, following are the steps to be followed:
Auto Rerun option for that test should be selected in Test Parameters screen.
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Prozone Limits, Technical Limits, Panic Limits and Reaction Absorbance Limit should be
checked in Test Parameters screen for the respective test.
Flags can be selected from Rerun Flags for which rerun schedule has to be sent.
Barcode Scan
On checking this option, the entire Sample and Reagents will be scan for barcode. After the scan
is over, reagent barcode details will get updated in Barcode Scan screen, Reagent Tray screen in
Status Monitor and also in Reagent Positions screen.
Re Scan
On checking this option, the system application will prompt user for a re-scan of unidentified /
unread barcodes at empty positions on the reagent tray after the default barcode scan is
completed. User can choose to re-scan barcode or he may skip and continue further activities.
The options under Reagent Level Scan option are used for scanning the volume of the reagent
present inside the reagent bottles before starting the run.
Reagent Level Scan option will be disabled when Barcode Scan check box
is selected.
If the option is checked before the run, and when the run started, all the reagents positions will be
scanned for reagent volume and the status will displayed on Reagent Tray screen and Reagent
Position screen.
All
Selective
All: This option is used to scan all the reagents defined in the Reagent Position screen.
Selective: This option is used for scanning the Reagent volume for only those reagents, which
are defined and required by the samples in current batch.
When you click on button, the following screen will be displayed.
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In the Selective Reagent Level Scan screen, by default, the reagents for the scheduled tests in
that batch run will be displayed as selected. See figure above. If user modified the selection, then
those selections will be memorized and displayed for next time.
If you do not want to scan the reagent level, uncheck all the tests selections.
In this case, MultiXL will only scan volume at positions where Wash
solutions, Serum Diluents and Urine ISE Diluents are defined.
After the scan is over, reagent volume details will get memorized and displayed in Reagent Tray
and Reagent Position screen.
If Reagent Absent, VOD or Liquid Level found different, errors are displayed
during pre-run activities then the corresponding reagent position is added to
the Refresh Positions screen. In this case user is advised to observe bottle
physically and take required corrective actions and then refresh the
positions manually to use that particular reagent bottle.
Run Options is available on the Status Monitor. Make sure that respective run options are selected
before start of the run.
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During run, when the pre-run operation is completed, the Work List screen may be displayed if:
If the tests are scheduled for the run and the reagent for the tests are not
defined, in this case the test will be masked and displayed in the Pending and
Masked Schedules (Patients) grid.
Similarly, If the tests are scheduled for a run and the gain for that particular
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wavelength is not within range, then the test will be masked and a pop-up
appears as shown below;
This section will displays the information about Sample Position, Sample ID with Container
type, Sample Volume Required, Sample Type, Test, Sample Volume, R1 Volume Defined, R2
Volume Defined (optional), Number of Reagents, R1 Position Available, R1 Volume Available,
R2 Position (optional) Available, R2 Volume Available (optional).
Test(s) in work list will be highlighted in red background, in case parameters (such as Sample
Volume, R1/R2 reagent positions, Reagent Volume defined etc) are not defined completely. In
such case, a message “Incomplete Test Details” will be displayed above the grid.
This section will display the information about reagent volume. Information such as RGT Type,
RGT Position, RGT Volume Available, Possible Test(s), Scheduled Test(s), RGT Volume
required.
If reagent volume available in the bottles is less than the reagent volume required for the total
number of possible tests then the column RGT Volume Available and RGT Volume Required is
highlighted with yellow background and a message “Reagent Volume Insufficient” will be
displayed above the volume grid.
Also, it will display the total number of possible tests (approximate) with the available reagent
volume.
Open count
Analyzer performs open channel tests, not exceeding total permitted Test-count & reduces test
count based on test(s) performed on the analyzer.
It will also intimate user during run if Open Count reaches 10 & below.
PROCEED
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If the tests details for all the tests are proper i.e. without any tests having background as red,
when this button is clicked, run will be started else run will not start.
CANCEL
Use this button to abort the run. However, clicking CANCEL during run will only close the screen.
Test(s) on Hold
Using this button, you can keep the specific test(s) on hold by masking them in work-list. User-
selected test(s) will be masked in the existing work-list as well as the new test order received
later, either through LIS or scheduled manually by user. On clicking, a test selection window
containing all the test(s) will displayed as follows.
User can keep one or multiple tests on hold by selecting the check box, as per your requirement.
Once tests are selected, click on OK button to save the selections.
Pending tests and masked tests are displayed in the grid at left bottom of the screen named as
‘Pending And Masked Schedules (Patients)’. To reschedule the pending tests, the corresponding
tests should be selected and clicked on RE-SCHEDULE button. Alternatively, the tests can be
selected from the Test list, select Pending option and click on RE-SCHEDULE button.
To reschedule the masked tests, the corresponding tests should be selected and clicked on RE-
SCHEDULE button. Alternatively, the tests can be selected from the Test list, select Mask option
and click on RE-SCHEDULE button.
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When the tests are selected during run, further tests will be masked.
But when the tests are selected before starting the run, then all scheduled
tests will be masked.
User can re-schedule the masked test(s) for all or selected samples, from
Status Monitor > Work List, even if the test(s) selected are on Hold.
Re-scheduling the Test(s) from the Work List will not automatically remove
the On-Hold status of the Tests.
The Work List screen can also be viewed by clicking on the Work List button
present on the Status Monitor screen.
The Work List screen displays the schedule for the group selected (from the
drop-down list below the buttons to Start and Stop run in Status Monitor
screen.
If the user wants to add a new bar-coded Sample or Reagent (Continuous Sample Loading), the
following procedure should be used:
On clicking, a message is displayed “Please wait, Tests are in progress…” The sampling
will be paused after completing the sampling of current in process test.
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3. Now user can open the dome and place new samples / reagents bottles at the appropriate
position on the tray.
4. Once the user is done with adding samples / reagents, ensure to close the dome and click on
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Added button.
5. After clicking Added, the sample barcode scan will be started and the message displayed
“Please wait barcode scan in process” on the screen. On completion of the scan, positions of
new samples will be updated in the Patient Entry and reagent will be updated in Reagent
Position screen. Please note that If dome is open, barcode scan will not be performed.
6. The user can see the scanned data by clicking Barcode Scan button on the same screen.
7. After barcode scan process, a message will be displayed “Please wait, Tests are in progress”.
Once the results of the ongoing tests are completed and declared, then run will continue.
Run will not continue until all the results for the dispensed tests are declared.
Manual Pause
During Run if user Click on (pause), Message Please Wait Sampling Is Being Paused is
displayed. Sampling will be paused after completing the current test in process. Following
message will be appeared to open dome.
Now user can add samples / reagent > Close dome > Click on Resume to continue RUN.
This button is visible only when the option ISE Module is checked in System
Parameters.
These details are viewable only before starting the run as this option is disabled during the run.
On clicking this button, the ISE reagent pack information will be displayed which contains.
Lot Number, Installation Date and Expiry Date of current ISE Reagent Pack
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Remaining ISE Reagent Volume Indicator (approximate remaining volume of Calibrant A and
Calibrant B; whichever is lesser).
The system detects New / Change in ISE Reagent Pack only on interacting with
ISE module (by clicking ISE ON from the Maintenance screen or on starting the
ISE run) or during Auto Maintenance operations. Hence, if the user clicks ISE
Details button just after (physically) installing the New ISE Reagent Pack,
system will displays the ISE Details of the earlier Reagent Pack.
1. Hence, if the user wants to use that position, then pause sampling first, and open Reagent
tray cover. After that put the new reagent bottle at reagent absent position, and then close
RGT cover. Then click on Refresh Positions button either from Reagent Position screen or
Status Monitor screen.
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3. This screen would display only those positions which have an empty bottle placed at that
position. If there are no empty bottles on the reagent tray then “Refresh Positions” button
would be disabled.
4. In the above screen, select the position which needs to be refreshed and click on OK to
refresh the position.
5. Select Auto Reschedule all possible tests (only for Reagent positions) option to reschedule
the pending tests. Click OK once the required reagent positions are selected.
6. Click on All to select all positions at once and click on None to deselect.
Scan pack option is used to scan the details of System Pack Reagent kits for Closed channel
reagents.
On selecting this option reagent pack details will be displayed which contains Reagent name, Lot
number, Expiry date, Manufacturing date and number of reagent bottles with volume.
Click Status Monitor > Scan Pack > System Pack Details > Scan pack > following details will
get displayed.
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Click Register, system pack will get registered and messages will be displayed as "XL System
pack registered successfully" as shown below
When user scans the system pack from Scan Pack and if scanned Reagent code is not defined in
Consumables then following message will be displayed as " RGT Code Unknown " that means that
system pack is not registered by system.
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To scan the Special Card, Click Status Monitor > Scan Pack > System Pack Details > Scan
pack > following details will get displayed;
Click Register, card details will get registered and messages will be displayed as "XL System pack
registered successfully" as shown below
Open channel tests can also be loaded using special cards which may be
available for purchase from manufacture in special circumstances.
6.3.7 Search
Consumable is used to search the patient information, sample information, patient results,
consumables, test parameters, calibration results and control results.
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Patient/Sample
Patient Results
Calib/Control Results
Consumables
Tests
6.3.7.1 Patient/Samples
Patient/Samples screen is used to search the patient and sample information.
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Parameters Description
Patient Name Enter the patient name.
Patient ID Enter the patient ID.
Doctor Select the patient's doctor name.
Sample ID Enter the sample ID.
Sample Type Select the sample type from the list.
Collection Date Enter the date range on which the sample is collected.
Reg. Date Enter the date range on which the registration is done.
Use two or more combination from above parameters to make advance search.
After providing necessary inputs, press Search button. The search results will be displayed in the
grid. In the search result, you can able to see the name of the operator and the modified date in
Operator ID and Modified On column.
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Parameters Description
Patient Name Enter the patient name.
Patient ID Enter the patient ID.
Doctor Select the patient's doctor name.
Flag Select the required flag from the list.
Test Select the required test from the list.
Sample Type Select the sample type from the list.
Sample ID Enter the sample ID.
Result Date Enter the date range.
Use two or more combination from above parameters to make advance search.
After providing necessary inputs, press Search button. The search results will be displayed in the
grid. Result Date column will displays results date along with time.
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Select the required consumable type and then enter any one or more parameters to search
the required output:
Parameters Description
Lot No. Enter the consumable lot number.
Test Select the name of test from the list.
Flag Select the name of flag from the list.
Enter the date range.
Result Date From
During run, the date difference to view the records should
be 30 day.
Result Date To
There is a choice of searching the entire consumables or selecting one consumable at a time.
After providing necessary inputs, press Search button. The search results will be displayed in the
grid. Result Date column will displays results date along with time.
6.3.7.4 Consumables
Consumable screen is used to search the consumable information.
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Select the required consumable type and then enter any one or more parameters to search
the required output:
Parameters Description
Manufacturer Select the list of manufacturer from the list.
Enter the expiry date range.
6.3.7.5 Tests
Test screen is used to search the tests parameter details according to the specified inputs.
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Parameters Description
Primary Wavelength Select the required primary wavelength.
Secondary Wavelength Select the required secondary wavelength.
Assay Type Select the assay type
Curve Type Select the curve type.
Reaction Direction Select the appropriate reaction direction from the available options.
6.3.8 Reports
Reports is used to view the patient reports, error log details, reaction curve, reagent consumption,
ISE calibration, sample information, patient results, consumables, test parameters, calibration
results and control results etc.
Patient Reports
Result Reprint
Test Statistics
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Calibration Trace
Calibration Monitor
Error Log
Reaction Curve
Other
Sample ID wise
Test wise
Doctor wise
Patient ID wise
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Parameters Description
From and To This option is used to select the date range.
If the user selects Location, then Patient Reports related to that Location
Location can be viewed depending on the From and To date selected. Click on
SHOW to display the selected reports.
It is possible to search the patient results batch wise. Patient Records are
Batch displayed depending on the batch number selected. Click on SHOW to
display the selected reports.
Select the sample ID by entering initial characters of the sample ID, and
then click on SHOW to display the selected report. This will displays the
Sample ID
patient report related to that sample ID, depending on the From and To date
selected.
Select the patient ID by entering initial characters of the patient ID, and
then click on SHOW to display the selected report. This will displays the
Patient ID
patient report related to that patient ID, depending on the From and To date
selected.
Select the doctor from the list. Click on SHOW to display the report. This
Doctor Name will displays the patient reports related to that Doctor, depending on the
From and To date selected.
Photometric Tests: If the user selects this option, then only photometric test results are
displayed. By default, this option is selected.
Calculated Items: If the user selects this option, then only calculation item results are
displayed.
Offline Results: If the user selects this option, then only Offline Entry results are displayed.
ISE Results: If the user selects this option, then only ISE Results are displayed.
Rerun Results: If the user selects this option, and then only Rerun results are displayed.
Recalculated Results: If the user selects this option, then only Recalculated Results are
displayed.
All: If the user selects this option, then all results (Photometric Test, Offline Results, ISE
Results, Rerun Results) are displayed.
Select the Report Options to display the following information on printed reports
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The report options will be memorized once the patient report is printed.
Online Patient Report printing will also use these memorized options.
Using the reports options, you can customize the generated report outputs.
Print Lab Details: This option is used when the user needs to print the Lab details. Refer
section System Parameters for entering the lab details.
If the user has clicked on the Print Lab Details check box, then the Laboratory details are also
printed in reports.
Hide flags: This option is used when the user wants to print the Reports without printing the
associated flags. If this option is selected, the column Flag will not be displayed in the printed
patient report.
In the printed report, the up and down arrow will be displayed if H and L
flag is attached with sample result.
The up and down arrow with H and L flag will be displayed even if the
option Hide Flags is selected in the Report Options in Reports > Patient
Report screen.
Show Location: This option is used when the user wants to print the Reports with or without
.printing the Location details.
Show Analyst: This option is used when the user wants to print the Reports with or without
printing Analyst details.
Show Sample Remarks: This option is used when the user wants to print the Reports with or
without printing the Sample Remarks.
Show Patient Remarks: This option is used when the user wants to print the Reports with or
without printing the Patient Remarks.
The labels Location, Analyst, Sample and Patient Remarks are not printed on
the report if the user de-selects them in Patient Reports.
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Normal
This is a basic report format. The order of printing results of photometric tests, calculated
items and ISE can be set from the Test Sequence screen using PRINT SEQUENCE FOR
PATIENT REPORTS option.
Multi Column
This format facilitates to print patient results in two-columnar format, like newspaper. See
figure below.
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Profile
If the user has selected profiles for scheduling tests from Patient Entry screen, then the user
can print Patient Reports as per the various Profiles selected.
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Graphical
Patient results and defined reference ranges are graphically represented in this format. Refer to
following figure for example.
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After selecting the required parameters, click SHOW to display the results.
Parameters Description
Last Batch Select this option to display the results of the latest batch.
Select this option to display results for a specific date or range of dates.
Date wise
Then select the From and To dates from the calendar drop-down list.
Parameters Description
Select appropriate option to view the details.
Patient or
Controls or During run, maximum 7 days data will be displayed for
Calibrations patients and maximum 30 days data will be displayed for
controls and calibration.
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Select this option to display results for a specific date or range of dates.
Date wise
Then select the From and To dates from the drop-down calendar.
Patient Name Select the patient name by entering initial characters of the patient name.
Patient ID Select the patient ID by entering initial characters of the patient ID.
Sample ID Select the sample ID by entering initial characters of the sample ID.
On selecting this checkbox, the patient records of all the dates present in
Any Date
the database are displayed.
Parameters Description
If you want to print the lab details on the printed patient report, check this
Print Lab Details
option and then click on Print button.
On checking this option, the additional column Patient ID and Patient Name
Print Pat ID,
column will be displayed on the print report in the landscape orientation. If
Name
this option is not selected, the report will be generated in portrait orientation.
Command buttons
Parameters Description
This button is visible only if the Host Connection in System Parameter
screen is checked. This button is used for sending the results to the LIS (if
they were not transmitted during run).
Send to Host
For any test containing "µ" in unit, "µ" gets transmitted as
"u" to LIS. User should avoid using uni-code characters like
"µ" in other fields, transferable to LIS.
Print This button is used for printing the Results on printer or PDF writer.
Export This button is used for export the Results on an excel sheet.
Use this button to invert the selection that is made. Clicking on this button
Inv. Selection
will select the unselected items and vice verse.
Select All Use this button to select all the results displayed on screen.
Parameters Description
Test Displays results as per selected test from list.
Sample ID Displays results as per selected sample ID from list.
Batch Displays results as per batch number selected from list.
Total Tests: This field displays the total number of tests performed for the selected criteria
Total Tests count will be refreshed only on click of SHOW button and not on
click of check box of every row in the grid showing data.
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To view the reaction curve, double-click on the Reaction Curve number in the
column “Curve #”. A new window with the curve and reading points displayed.
Click on “Close” button to close this window and go back to the Result
Reprint screen.
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Parameters Description
Date From Enter the beginning date for the results to be analyzed.
Date To Enter the ending date for the results to be analyzed.
Use this option to view the results batch wise. Batch number will be
Batch
displayed only when date is same.
Select the test name to view its statistics. Results of the selected test
Test which is performed on the analyzer is displayed according to Patients,
Controls or Calibration selection.
Select this option if test statistics for a particular age group is required.
Age
Enter age range and press Filter button to get the result.
Select this option if test statistics for a particular test value is required.
Result
Enter age range and press Filter button to get the result.
In case, the user requires the laboratory details to appear as header on the
Print Lab Details
Test Statistics report, then select this option.
Use this option to view result statistics of specific rows displayed on the
S#
screen. Then enter the range of rows in the Start From and End To.
Use this option to specify patient name/consumable for which you want to
Patient Name obtain the statistics. Then enter first few characters of the patient or
consumable name.
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Statistical Details
Normal Range: Displays the total number of results that were within the normal range defined in
the Reference Ranges screen.
Above Normal Range: Displays the total number of results that were above the normal range
defined in Reference Ranges screen.
Below Normal Range: Displays the total number of results that were below the normal range
defined in the Reference Ranges screen.
Not defined: Displays the total number of results whose reference ranges were not defined in the
Reference Ranges screen.
N: Displays the total number of tests used for calculating the Mean, SD and %CV for a test.
Mean: Displays the average of the result/absorbance that has been selected (checked).
SD: Displays the Standard Deviation of the result/absorbance that has been selected.
%CV: Displays the %CV (coefficient of variation) of the result/absorbance that have been selected
(tick-marked)
Range: Displays the Range of the results that fall within the selected criteria. It shows the
difference between the minimum and maximum range for the same.
Sr#: Use this button to select the range of results/absorbance’s for which you want to obtain the
statistics. Enter the range in Start From and End To textbox. Once the range is entered, click on
Calc button to obtain the statistics.
Command Buttons
Select All: This button is used to select all the sample records for a test.
Print: This button is used for printing the Test Statistics for the selected Test in Report format.
Export: This button is used to export the Test Statistic details into the excel sheet and saved in
location C:\MultiXLLOG\TestStatistics.
Calc: This button is used to recalculate the statistics in the other grid at the left-bottom corner of
the screen; as per the result data displayed in screen (based on the sub-filters, such as Sr#,
applied to the result data).
Reset: This button reset the values entered in the Start From and End To textbox.
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Parameters Description
It is used for selecting the desired test whose calibration history needs to be
Test Name
viewed.
It is used for selecting the month and the year for the test whose calibration
history needs to be viewed. Once the test and the month selection are done,
the grid displays the different calibration dates and time along with the
Month and Year
absorbance’s for blanks and standards. Also, a graphical representation of the
Blanks and Standards can be viewed.]
Blank: It is used to change the range of blank absorbance.
Standard/Calibrator Use Reset button to reset the range for blank, standard and calibrator
absorbance to range according to the minimum and maximum absorbance of
the blanks, standards and calibrators.
Use Export button to export the data and graph displayed on screen to an excel sheet.
Use Print button to print the data and graph displayed on screen.
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Column Description
Test Test name
Curve Type Type of Curve assigned for that chemistry
Type Either Blank or Standard S1,S2…etc
Consumable Name of the consumable
Lot# Lot no. of consumable used
Conc. Concentration of the consumable
Abs. Absorbance of the Blank/Standard
Factor Factor value of the standards
Calib. Exp Calibration Expiry Limit (in Days)
Acceptable Limit Acceptable Limit for New Factor
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2. Select the operation (All, Run, Service, Maintenance, or Host operations) during which the
errors occurred.
4. Use Error Code drop down list is used to filter the records as per requirement.
Error Code – Displays the error code to identify the type of error occurred.
The column “Action” represents the severity of the error, which is as follows:
Pause-P states that the sampling will be paused on occurrence of such errors
during run. User may take corrective action and resume sampling by clicking on
the Resume button from Status Monitor.
Pause-R states that the sampling will be paused on occurrence of such errors
during run. On occurrence of such errors, resume sampling in same batch is not
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possible. Once the results of all the tests in progress are declared, the batch run
will stop. When the batch run is completed, user should take corrective action and
then start the run again.
STOP states that the analyzer will stop the batch run immediately on occurrence
of such errors.
6. To print the details of the error log, user can click on Print button.
7. Use EXPORT button to save the records in the excel sheet. On clicking, the details will be
automatically copied in the excel sheet and the file is saved in the particular location. The
location will be displayed in the Indication text box.
The reaction curve can be viewed test wise and sample ID wise for patient results or Test wise and
Consumables wise for Blank, Standard/Calibrator and Control Results.
Click on the dotted button near the test text box to select the requiredtest. Click on the dotted button
near the Sample ID text box or consumable text box to select Sample ID or Consumable
respectively.
Use crossed button to clear the respective selection criteria in the adjoining text box, as required.
See the following figure.
Alternatively, one can also search a specific curve number by ticking Search By Reaction Curve
No. check box and then entering the reaction curve number in Curve No. text box (It allows to enter
up to 9 digits). The user has to click on SHOW to view the reaction curve as per selection.
Reaction curve number is a unique serial number assigned by the program during analysis. The
reaction curve number can be obtained from the Result Reprint screen. The absorbance values for
the selected time course are displayed in a tabular format as well as graphically.
M1S, M1E, M2S, M2E and Extended M2E and also Ap, As, Ap-As for a particular chemistry are
shown on the time course. These points can be identified by legends placed below the time course.
The time course display also contains the following details regarding that reaction curve.
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Primary Wavelength: It displays the primary wavelength to be used for measurement of that test,
as set in the Test Parameter > Test Details screen.
Secondary Wavelength: It displays the secondary wavelength to be used for measurement of that
test, as set in the Test Parameter > Test Details screen.
Assay Type: It displays the Assay Type for that test, as set in the Test Parameter > Test Details
screen.
Average O.D./Delta Abs/min: It displays the Average O.D. for End Point Assays or Delta Abs/min
value for Rate Assays; calculated within the specified time intervals for that test. .
Format: It allows selecting either to display in the graph only Ap (Absorbance at Primary
Wavelength) or only As (Absorbance at Secondary Wavelength) or both Ap and As or Ap-As or All.
Click on to zoom in / zoom out the Y axis (Absorbance) scale to enlarge the graph within the
minimum and maximum absorbance for that curve. Click twice on the Reaction Curve graph to obtain
a zoomed view. Double-click again to zoom out.
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Use navigation buttons to view the previous or next reaction curve number details.
PRINT: Click on this button to print the reaction curve details along with the graph.
EXPORT: Click on this button to export the selected reaction curve details along with the graph to
the specific location. After exporting the data successfully, the file name along with the path is
displayed as a message as well as in Indication text box in the bottom of the screen.
CLEAR: Click on this button to remove the details of the selected reaction curve number.
6.3.8.8 Other
Reagent Consumption screen in used to display the following information:
Use SHOW to view the data over the selected date range.
Use EXPORT to export data in excel sheet. Excel sheet is saved in the location C:\MultiXLLOG\ in
the *.XLS format.
Reagent Consumption
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Reagent Consumption option is used to view the total number of times the each test are
performed for Patient, Calibrator (including Blank and Standards) and Control on the analyzer.
You can obtained the required data by selecting Reagent Consumption radio button and
entering date range. After selecting date, press SHOW to display the data.
ISE Calibration
Select ISE Calibration radio option. This will displays the calibration details on the screen.
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Using this option, you can view list of discarded / Non Discarded / ALL reagent bottles. The data
can be obtained by selecting date range in the From and To drop-down list.
To view the Discarded / Non-Discarded / ALL bottles, go to Reports > Others and select Reagent
Bottle History option, select required date range,select option Discarded / Non-Discarded / ALL
from drop down list as shown in below figure.
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In Bottle no. column, the first three digits denote the Lot no. whereas the next
four digits denote the Bottle no. of the reagent bottle.
Pack Details
This option is used to give details of System Pack Reagent kits. User can view list of details as
Pack no, Reagent name, Register date, Lot no, Mfg date, Expiry date, Open count no, Volume
scanned from pack up to 2 decimal, Bottle type, Bottle no, Discard status and date. The data can
be obtained by selecting date range in the From and To drop-down list.
To view the Pack details, go to Reports > Others > Pack Details option,select required date
range and then click on SHOW. The following screen with data will be displayed.
This option provides details of open test count after registry of system packs and special cards.
User can view the list of details as Pack no, Reagent name (for special card it shows as CARD),
Registration date, Expiry date, Validity, Open Counts, Open Counts Balance and expiry of card.
The sorted data can be obtained by selecting ALL / Expired / Balance from drop-down list.
To view the Open Test Counts, select Reports > Others > Open Test Count Details, select
required options from ALL / Expired / Balance and click SHOW. The respective details will be
displayed.
Validity (days) If available on reagent pack / card, then it will be stored for expiry of days counts
loaded from the respective pack.In case, validity of Open-counts is not available from reagent
Packs / cards then it consider as no-expiry for those Open counts.
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Open test counts will get incremented after registered of reagent packs or special cards.
System will consume the Open Test Counts in the order of their Expiry. Thus, open test counts
without Expiry (from existing packs) will be consumed at the end. It will not use Open counts after
respective Expiry (validity) & before its scan-date.
Open-channel tests will be allowed only till open counts is available
6.3.9 Master
Master menu is used to enter the master details such as area, doctor, analyst, laboratory,
manufacturer, reference range, unit, calculation formula and instrument.
Area
Doctor
Analyst
Laboratory
Mfg
Reference Range
Unit
Calculation Formula
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Instrument
Unit Conversion
6.3.9.1 Area
Area screen is used to enter the area (Location) from which the samples are collected. This list of
area is available in Patient Entry screen and hence for each patient a particular area can be
selected. This selected area (location) is printed in Patient Report.
6.3.9.2 Doctor
Doctor screen is used to enter the name and demographics of referring doctor. This list of doctor is
available in Patient Entry screen and hence for each patient a particular doctor can be selected.
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6.3.9.3 Analyst
Analyst screen is used to enter the name and demographics of analyst. This list of analyst is
available in Patient Entry screen and hence for each patient a particular analyst can be selected.
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6.3.9.4 Laboratory
Laboratory screen is used to enter new or edit the existing laboratory name with their details. These
details will be printed as a header in the patient reports.
There is always a default row with laboratory name as My Laboratory marked with ** sign. This row
cannot be deleted but it can be edited. The name and address of this row is printed as header in the
patient reports.
This list of laboratory is available in Utility > Offline Results screen and hence for each patient a
particular laboratory can be selected.
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6.3.9.5 Mfg
Mfg screen is used to enter new or edit the existing manufacturer name. This list of manufacturer is
available in Consumables screen and hence for each consumable a particular manufacturer can be
selected.
There is always a default manufacturer present marked with ** sign. This row can’t be deleted but it
can be edited that is the name can be changed.
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There is always a default row present marked with ** sign. This row can’t be deleted, it can only be
selected.
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6.3.9.7 Unit
Unit screen is used to enter the unit. This list of units will be displayed in Test Details and
Calculated Item screen and hence for each test a particular unit can be selected.
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Commonly (or frequently) used calculation formula are provided as default list. New formula can be
added to list, as required.
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6.3.9.9 Instrument
Instrument screen is used to enter instrument details. This list of instrument will be displayed in
Offline Results screen and hence for each offline result a particular instrument can be selected on
which result was measured.
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1. Select the Unit conversion > from Master > there are radio buttons >Test and Calculated Item
and Check box for General > select TEST tab.
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2. Select the test from the drop down list. From unit is mandatory and non editable, To unit > Select
the unit from the drop down list, Enter the appropriate factor for conversion.
3. Select Save > Test grid displays the test for which unit to be converted.
4. To convert unit for Calculated Item > Select the Calculated Item tab > from drop down list, select
the the calculated item, From unit is mandatory and non editable, To unit > to convert the unit
from the drop down list, Enter the appropriate factor to conversion.
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.
5. Select Save > Calculated Item grid displays the test for which unit to be converted.
6. Tick the check box General for unit applicable to all tests and calculated items.
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7. Select From Unit from drop down list > Select To Unit from drop down list
8. Click Save> General grid displays the unit to be converted which is applicable to all tests and
calculated items.
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6.3.10 Utility
Utility allows user to perform the following operations:
Reagent Positions
Backup
Offline Results
Recalculate
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If the reagent bottles are bar-coded, then they do not need to define positions as they are
automatically updated and displayed after the Reagent Barcode Scan. Reagent volume will be
updated automatically when the Volume Scan is performed through Status Monitor.
Also, using this screen you can also edit or clear the defined reagent positions.
Clear position :Clear Position used to clear the defined reagent positions on the reagent tray. There
are two sub options:
Edit Position :Use this option to add or alter the reagent definition at a specific position.
Refresh Positions :This is used to notify the availability of reagent in the reagent bottle(s) on the
reagent tray. During the run, when a reagent bottle is detected as empty bottle (no volume) then such
reagent position is de-activated and not used for further aspiration of reagent. Replace the empty
reagent bottle on the reagent tray with the filled reagent bottle. Then use this option to notify the
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Scan pack: This option is used to scan the details of System Pack Reagent kits for Closed channel
reagents. Refer section Scan Pack for more details.
Transfer To Tube: This option is used to utilize tube by transferring reagent from scanned barcoded
reagent bottle to tube. For details refer section Transfer To Tube
Keys – Empty Bottle and Expired Lot: These keys indicate the meaning of the white and red
background color used for the rows of the positions grid displayed in the screen.
Empty Bottle: When a row is highlighted with white background color, it indicates that the
reagent volume at that position has become zero during run.
Expired Lot: An expired reagent lot on the reagent tray is highlighted with red background
color. The expired reagent is not aspirated during run. However, volume scan will be performed
for the position(s) having expired lot.
Expiry date of reagent bottle is compared with batch run start date, to decide
whether or not to aspirate the reagent during run.
Parameters Description
Position Reagent positions on Reagent Tray.
Reagent Reagent name.
Type Reagent type (R1/R2).
Bottle Type Bottle type of the reagent (Large / Small / Tube).
Rgt Vol (ml) Reagent volume scanned (ml).
Lot No. Lot number of the selected reagent
Expiry Date Expiry date of reagent as defined in consumables / read from barcode
Barcode Barcode label read on Reagent Barcode Scan.
“-“in this column indicates manual definition of reagents.
Stability Onboard stability period as defined in consumables.
Unit Unit of the stability period, hours/days as defined in Consumables.
1. Scan barcoded reagent bottle from which you want to use reagent in the tube.Analyzer will get
details of reagent bottle on scan.
Barcode scan of each reagent bottle is required ONLY ONCE.
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Ensure, the reagent pack from which you removed the bottle, is already scanned with
Test Loader Device.
2. Once barcode is scanned, fill the reagent into tube from scanned barcoded bottle only.
3. Place this tube at the place of same bottle position.
4. Click Utility > Reagent Position > Transfer To Tube.
5. Select the scanned reagent bottle position from which reagent to be transferred to tube
6. Click Transfer To tube. Reagent position box appears.
10.Click OK. Click Reagent position, reagent which is transferred to tube now appears in bottle
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type as Tube.
11.Ensure sufficient reagent in tube to complete the run.If reagent is not sufficient then fill the tube
from same reagent bottle (scanned in step 1).
In case scanned reagent bottle is over, scan another bottle from same system pack, follow the
procedure for Transfer To Tube to continue run.
In case all bottles of same system pack is consumed, scan new system pack (Refer section
Scan Pack for more details) and then follow the procedure for Transfer To Tube to continue run.
12.Start the RUN, analyzer will use reagent from tube to complete the run.
13.Before starting the next batch RUN, check if reagent in tube is sufficient to complete the run
otherwise fill the reagent from earlier scanned bottle into tube and start run.
If user wants to deselect this position then use either Clear Position option or
can keep any barcoded bottle on that position so that respective tube position
will be replaced by barcoded bottle after barcode scan.
After Reagent Barcode Scan, Reagent Position marked with Transfer to Tube will be retained
across the batch till user either manually modifies the position or scans bar-coded Reagent bottle
on that position.
During Volume Scan, like bottle; when Reagent Absent, VOD or Liquid Level found different etc. is
reported then add respective tube Position to Refresh List; such that Tube is not used till user
refreshes the position (after taking appropriate action like fill tube from respective scanned bottle,
remove froth/bubble etc).
System will track reagent volume used in tube for new as well as used reagent bottles.
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Tube is not allowed for discarded reagent bottle, until next barcoded bottle is scanned.
6.3.10.3 Backup
Backup screen is used to take the backup of the patient database and to copy data to external
storage device.
Backup Operations
Backup Mode: The display changes according to the selection and provides necessary guidance to
perform the operation.
Two options are available. Full Backup and Selective Backup. Only full backup is re-storable.
Selective backup is used to extract partial data for reference and cannot be restored back.
Backup Format: This drop down list is used to select the Mode of Backup. Available options are
Text, XML, XLS, and CSV. These options are available if the Selective Backup option is selected.
XML: This mode of backup stores the Backup Parameters in XML format
Text: This mode of backup stores the Backup Parameters in Text format
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XLS: This mode of backup stores the Backup Parameters in Excel format
CSV: This mode of backup stores the Backup Parameters in Excel format.
The option Database will be displayed if Full Backup option is selected. Using this option, a backup
file of complete database is created in .BKP format along with .ARH file (.ARH file is a full backup of
Archived data).
Backup Path: Click on the Browse button to select the path or directory where the Parameters will
be backed up. It is not recommended to take the backup on the desktop.
Database: This mode of backup copies the entire database and stores it on the hard disk at the path
selected by user using Browse button.
Backup Option: A list of parameters is available for Backup if the user selects the Selective Backup
mode. The user can either check all the parameters using Backup Option/All checkbox or make a
selection individually using the checkbox placed against each parameter.
After the above operations have been done, click on Backup button to take a backup of selected
parameters.
Full MultiXL Database Backup and Log files are automatically archived in the C
drive under MultiXLLog folder, after every seven days before system shutting
down.
The option is provided to copy database backup, log files and exported report files on USB storage
device.
On Windows Embedded 7 as Operating System, the USB storage device is blocked by default. To
copy data to USB storage device, log in as Administrator (windows user login) and run MultiXL.
1. Login as Administrator on the analyzer PC and start MultiXL software. (This step is only for
Windows Embedded 7 as Operating System on PC. It is not required for Windows XP and
Windows 7 Professional).
4. Following options are available to copy data on USB storage device. Select any one, as
appropriate:
Only Database: Database full backup, .bkp file will be copied to USB.
Only Log Files: Copy log files from the location C:\MultiXLLOG into USB device.
Both Log Files and Database: Both, Log files as well as Database as per specified
date, will be copied to the USB device. Following options are visible on selection.
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Full
Folder To External Drive: The folder (along with its contents) selected from the
analyzer PC, termed as Source Location, will be copied to the USB device.
Exported Reports: System will copy all exported reports (present in designated folder
on hard disk drive) like Result Reprint, Test Statistics etc. to USB device.
Exported Reports: System will copy all exported reports like Result Reprint, Test
Statistics etc. to USB device.
5. User can select any one of the above options and select the Destination Location i.e. the
USB device.
6. Click the Copy Analysis Data button to copy data based on user selection.
7. On completion of data copy, message will be displayed as “Analysis data copied to the
destination location successfully” in the indication panel.
6.3.10.3.3 System Backup Restore
System Backup Restore option is provided to take backup of setting files and database on any other
D / E drive (auto drive selected by system) except from the C drive.
System Backup will be taken on MultiXL Shut Down. After taking weekly backup, old database
backup will be removed from c:\MultiXLLOG_Backup
User can also take system backup manually by following steps;
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5. To Restore the files user needs administrative rights otherwise Restore button will remain
6. Run Database Utility to restore the backup of database. Refer section Database Utility Options
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In case, if the result is entered for the test(s) that is available in test parameter then the result will be
saved with decimal places as defined in test parameter for the respective test. When the result is
entered for a new test i.e. for test that is not in test parameter; then the result will be saved with
decimal places as entered.
Item Description
Select the date for the patient result. It will always display the current date
Date
by default.
By clicking on the dotted button, select the name of the Laboratory from
Laboratory
the available list. Use Master > Laboratory screen to add a new laboratory.
By clicking on the dotted button, select the name of the Instrument (from
Instrument the available list) on which the test is conducted. Add a new instrument
name from Master > Instrument screen.
By clicking on the dotted button, select the Sample ID, if already defined
Sample ID
from Patient Entry screen or directly enter the sample id in this textbox.
Sample Type The user can select the Sample Type from drop down list.
Enter the name of the patient. The name of the patient will be displayed
Patient Name
automatically if the Sample ID is selected from the dotted button.
Age It displays the patient’s age..
Category This list displays the Category (Gender) of the patient.
Select the required test name from drop down list or enter a new test name
Test
up to 5 characters.
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Report Name Enter the Report Name of the selected test, for printing in Patient Report
Unit Select / enter the Unit of measurement for the test.
Normal Lower Limit Enter the Lower Limit of the Normal Reference Range for the Test. By
default, the reference range will be displayed when the test available in
Test Parameter is selected from the list of Tests.
Normal Upper Limit Enter the Upper Limit of the Normal Reference Range for the Test. By
default, the reference range will be displayed when the test available in
Test Parameter is selected from the list of Tests.
Result Enter the result for the Test.
Flag Enter the Flag associated with the Result.
6.3.10.5 Recalculate
Recalculate screen is useful in recalculating results if any changes are made in the test parameters
or calibration data after analysis. This is particularly useful because one does not have to rerun a
sample if a mistake was made in test parameters or the calibration table.
Results of the test(s) having flags for Sample/Reagent absent cannot be re-
calculated.
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Sample ID textbox will be disabled if option Calibration or Control radio button is selected.
4. Select the result(s) for which re-calculation is required. Click on the Recalculate button. The
re-calculated result and flag (revised as per re-calculated value) are displayed along with the
original result and flag.
5. Recalculated test results can be sent to Host by selecting the results and clicking on the
Send To Host button.
.
Send To Host button will be available if:
Patient or Control option is selected for showing results.
Host Connection option is activated in System Parameters screen.
During run, the Send to Host button is not available in the Re-calculated screen
and Result Reprint screen.
The option ‘Ignore Limits to Re-calculate Results’, allows user to display the
recalculated result with ignoring limit flags.
If this option is not selected, NA will be displayed in the Result column.
The options in the Service Check are not accessible if any maintenance/batch
run operation is running through the maintenance/status monitor screen. In this
case, the status message will be displayed to the user.
When starting the Service Check activity, if dome is open (Level 1 and Level 2 )
then following warning message with alarm beep will be displayed and error
message will be reported in error display grid.
Service Check screen is used to perform the perform service related activities.
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Arm/Stirrer Alignment
This option Arm and Stirrer is used for checking the alignment of the arm probe or stirrer
assembly. Upon selecting the Arm or Stirrer option, the service personnel can check the
alignment of the respective assembly in trough, in sample tray (outer, middle and inner positions),
in reagent tray (outer positions and inner positions), in cuvette & in dilution cuvette. The operator
can check stirrer motor rotation speed at three different options.
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Initialize
This will initialize the arm assembly as per the available options selected from the list.
Dummy Run
On clicking this button, user can define the Sample, Diluent and reagent position. After defining
the respective positions, on clicking START button, Dummy run is initiated. On clicking STOP
button, Dummy run can be stopped when required.
Execute
This will move the respective assembly in the selected path. This is used to check the motion of
an arm assembly in a particular path. Also for checking the opto conditions.
Sample/Reagent Tray
Initialize
This will initialize the SRGT tray and bring it to its home position.
Pulse
This will move the SRGT tray in one micro steps, each time the button is clicked.
Barcode Scan
This will scan all the inner and outmost positions of SRGT tray and will display the scanned
barcode details. After scanning, a barcode image will be displayed below the Barcode Scan
button. On clicking, it will display the list of scanned barcode details with position numbers.
This option is also used to check the barcode scanner alignment and also for checking barcode
labels.
Rotate to Position
This is used to bring a specific Reagent or Sample container below the sample/reagent probe
pickup position. The required position can be selected from the available drop down list.
Rotor Tray
Initialize
This will initialize the Rotor tray and bring it to its home position.
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Pulse
This will move the Rotor tray in one micro steps, each time the button is clicked.
Rotate to
This is used to bring a specific well in front of photometer so as to check the centering of beam or
intensity of light falling from lamp. The required position can be selected from the available drop
down list.
Lamp
Syringe
Initialize
This is used to initialize the selected syringe assembly.
Aspirate
You can check the ASPIRATE steps by entering the desired volume in the field provided. The
maximum volume that can be entered for ASPIRATION movement is 375ul.
Dispense
You can check the DISPENSE steps by entering the desired volume in the field provided. The
maximum volume that can be entered for DISPENSE movement is 375ul.
These buttons are used to check the flow of water from the respective troughs and internal tubing.
The following options are available:
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Waste Pump
ARM Probe Clean Valve: Turns ON or OFF the arm probe clean valve.
READ: This button starts reading operation and given Temperature Display till Stopped.
STOP: This button should be clicked before moving out of next screen.
L- Loose (This error will occur when there is any grounding problem of sensors)
Calibration
This section is used to calibrate arm centering at various applicable positions. Pre-requisite for
this operation is to bring the arm to required position using the ARM options.
Accept: Saves the Course / FINE adjusted value of ARM in to local memory. Values are not
saved in Analyzer until “Save Calib.” Button is clicked.
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Cancel: Cancels the locally Accepted Value(s) of Course / FINE adjustment(s) of ARM.
Default: Cancels and reloads the default position of ARM at respective position of calibration.
Save Calib: This option is mandatory after calibrating the ARM. The locally Accepted values are
Saved in the Analyzer Non-volatile memory and are used by Analyzer henceforth.
Calibration Menu
Read Default Calibration: This option will transfer the new default data (if any) from the ESW
(CPU) to PC.
Read Current Calibration: This option will transfer the current data from the analyzer (i.e.
EEPROM of CPU) to PC.
Load Default Calibration: This option is to load the default values from the PC to analyzer (i.e.
EEPROM of CPU).
Show Current Calibration: This option will displays the current calibration values in the
analyzer.
Current Calib Backup: This option will take the backup of current calibration which is saved in
the EEPROM to PC.
Restore Current Calib Backup: This option will load the backup file onto the EEPROM of the
CPU.
Communication
This option is used for checking the communication between PC and the analyzer. The service
personnel select the COM port and then click on the Check button.
Misc Commands
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This option helps to view the version numbers of MuliXL Software and Embedded Software
versions (Analyzer, Micro Blaze, FPGA). Click on this button, and then select “EMB Software
Version” which appears as shown below;
The software's and their corresponding version numbers will be displayed as shown below;
Emergency Stop
When the instrument is executing any service related functionality, at this point, if any malfunction
of assembly or sudden hazard is encountered, the user can take the following actions to
immediately put the instrument at halt.
The user can click on Emergency Stop button. This will stop or halt the functionality currently
being executed and displayed the respective error occurred on the screen.
The instrument will remain halt at the same condition where emergency stop had occurred. This is
to help the user to see the condition of instrument and verify the cause of the error. After
Emergency Stop command, the instrument will initialize all the assemblies. This initialization
ensures that all the assemblies are at their Home positions so as to begin the next command.
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In case the malfunction occurred is fatal and the instrument is not able to come to its stable state
then the user needs to switch OFF the Mains Switch provided on the right side of the instrument.
This will turn OFF the instrument and will not allow further hazard. The user can turn ON the
instrument again so as to restart the functionality.
6.3.12 Maintenance
During Maintenance activity when dome is open ( Level 1 and Level 2 ), then
following warning message with alarm beep will be displayed and error
message will be reported in error display grid.
Maintenance
Cell Blank
Maintenance Log
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During Run, the Maintenance screen is disabled. User can access this screen only
after completion of the ongoing Batch Run.
6.3.12.1 Maintenance
Maintenance is used to perform the routine maintenance of the analyzer.
Wash
ISE Unit
Auto Maintenance
Auto Span : This option is useful to view and adjust the photometer gains at different wavelengths.
The analyzer adjusts the photometer gains automatically if you select Auto Span option and click on
START button.
The gain should be in range 350 –900. If the gain obtained for any wavelength is not within the range,
it is highlighted with red background else if within range then with green background.
The photometer gains can also be adjusted manually, however it is not recommended.
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Manual Span: This option is useful to view the absorbance and voltages at different wavelengths. It
is also used to view the photometer stability at different wavelengths.
Before starting the Manual Span set, it is necessary to do one Auto Span set so
that a cuvette filled with DI water stands between the lamp and the
photometer.
1. Select the required wavelength using which the absorbance and voltage needs to be checked.
2. Select the appropriate cuvette number from the Cuvette No. drop down list.
4. The continuous online update of voltage and absorbance takes place and is displayed on the
screen.
6. User can select another wavelength to check the voltage and the absorbance at the other
wavelength. Again user needs to click on Start to start the reading and Stop to stop the
reading.
NOTE:
6.3.12.1.2 Wash
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Rotor Check
Select this option to perform a rotor check operation for a rotor by clicking on the Start button.
When it is started, it will perform auto span operation. During auto span, it will check the gains for
all wavelengths. If the gains are not in range, then rotor check operation will be aborted, and the
rotor status will be displayed as “Gains not in range”. If the gains are in range, then it will check
absorbance for all 120 wells.
At the end of rotor check, software shows whether the rotor has passed the test or not. The cell
blanks are updated automatically and can be seen by clicking on the Cell Blank screen under
Maintenance menu. If the rotor checked is declared as fail, user can see cell blanks for each well
why the rotor has been shown as “Fail”. See section Cell Blank for more details.
Probe Wash
1. This option enables the operator to wash the Probe with Auto Wash AC (Acid) or Auto Wash
AL (Alkali) cleaning solution at the end of a day’s work or at beginning of the day. This
operation can be performed any time using this option.
2. Fill 10 ml cleaning solution in a reagent bottle and place it on position 1 in the SRGT tray. And
place empty 2 ml cups in position 4 and 6.
4. On clicking, the following message box will be displayed indicating the user for placing cleaning
solution.
5. Click OK.
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Use Auto Wash AC (Acid) or Auto Wash AL (Alkali) cleaning solution for
sample probe wash.
Prime Wash
This option is used at the beginning of the day, if user wants to have priming again. The syringe
valve of the Probe is kept ON and the Syringe pump is moved to extreme down position to remove
the air trapped inside the tubing’s and syringe pump.
1. Machine Initializes.
4. Syringe valve is made ON/OFF several times to create turbulence for probe cleaning &
trapped air removal.
5. After approximately 2 minutes, Syringe pump is initialized for its home position & valve
made OFF.
This option is a default factory set value. User cannot define and input these parameters.
This screen used to calibrate the Dead Volume for Sample Containers and Reagent Bottles. This
procedure should be carried out at time of software installation (application or analyzer embedded).
Use the following procedure to carry out the dead volume calibration:
The following steps should be done to carry out the reagent bottle calibration:
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1. Select the type of reagent bottle from the container type list.
2. Fill the exact volume in reagent bottle as specified for selected bottle type.
3. Keep the reagent bottle according to the position specified for selected bottle type.
5. If the reagent volume present in the specified reagent bottle is not approximately equal to the
volume with which it is to be calibrated, then message “Calibrated Value Out of Range of
Specified Value” is displayed.
6. If the calibration is within the range, a message “Dead volume calibration successful” is
displayed and automatically saved.
The following steps should be done to carry out the sample tube calibration:
1. Select the type of sample tube from the container type list.
2. Keep the sample tube according to position specified for selected bottle type.
3. Fill the exact amount of volume in the sample container as specified for dead volume.
5. Once the calibration process is completed then a message “Dead volume calibration
successful” is displayed and automatically saved.
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The following steps should be done to reset the dead volume calibration to default:
2. Select the container type from the list for which the dead volume calibration needs to be reset.
These options are used to perform the routine maintenance, purging, cleaning and calibration on the
ISE unit. This option is available only when ISE (Ion Selective Electrode) unit is installed on the
analyzer.
Purge A
This is used to purge Calibrant A solution through the tubing from the reagent module to the ISE
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Module. The ISE Module pumps Calibrant A from the reagent module through the ISE Module to
wash out the flow path.
On successful PURGE A cycle, it is indicated by green colored box, if it is failed, then red colored
box will be displayed on the right side of the ISE maintenance screen.
Purge B
This is used to purge Calibrant B solution through the tubing from the reagent module to the ISE
Module. The ISE Module pumps Calibrant B through the ISE Module to wash out the flow path.
On successful PURGE B cycle, it is indicated by green colored box, if it is failed, then red colored
box will be displayed on the right side of the ISE maintenance screen.
Calibration
This cycle is used to calibrate the electrodes (Na, K, Cl, and Li) of ISE Module. The ISE
calibration range is as follows:
Na : 52-64
K : 52-64
Cl : 40-55
Li : 47-64
On successful calibration cycle, if the values are in range, it is indicated by green colored box. If it
is not in range, then coral (deep pink) colored box will be displayed.
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On clicking SHOW REPORT, it will display the last 30 calibration values. See figure as shown
below.
Clean
This command is used to remove protein build-up from the ISE Module electrodes. The Clean
command should be performed once per 24-hour period.
On successful operation, it is indicated by green colored box, if it is failed, then Coral (deep pink)
colored box will be displayed.
Pump Calibration
This cycle is used to calibrate the peristaltic pumps of the ISE Module. On successful operation,
it is indicated by green colored box, if it is failed, then Coral (deep pink) colored box will be
displayed.
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Bubble Calibration
The bubble calibration command is used to allow the module to reestablish a baseline for
detecting air-liquid interfaces. It can also be used as a diagnostic tool to see if the bubble detector
is functioning properly.
On successful operation, it is indicated by green colored box, if it is failed, then Coral (deep pink)
colored box will be displayed.
Maintenance
This is used to clear fluid from the flow path of the ISE Module, and to pause the Sip Cycle.
The Sip Cycle is used to refresh the Calibrant A in front of the electrodes. Every 30 minutes after
the last sample is run, the ISE Module will automatically run a Sip Cycle. No command is
required from the host analyzer to initiate a Sip Cycle. The ISE Module automatically clears the
flow path, next the ISE Module dispenses 36 µL of Calibrant B into the Sample Entry Port, and it
pulls it past the electrodes using the waste pump. The ISE Module then dispenses 95 µL of
Calibrant A into the sample entry port, and positions it in front of the electrodes.
On successful operation, it is indicated by green colored box, if it is failed, then coral (deep pink)
colored box will be displayed.
Prime A
This command is used to prime Calibrant A solution from the reagent pack. It is performed after
installing the new ISE Reagent Pack.
Prime B
This command is used to prime Calibrant B solution from the reagent pack. It is performed after
installing the new ISE Reagent Pack.
This command is used to display last calibration values for the Na, K, Cl, and Li.
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ISE ON
When this button is pressed, the system will check for the (calculated) volume of Calibrant A and
Calibrant B.
In case, if the remaining (calculated) volume of any Calibrant is less than 10% of the total Volume
then the message “ISE Reagent Pack Volume Low (Less than 10% of Total Volume)” will be
displayed in error grid and logged in the database. This message is only for the user information.
In case, if the remaining (calculated) volume of any Calibrant is below the respective threshold
level, then the alert message “ISE Reagent Pack Volume Very Low (Less than 3 Days Sip)” will
be displayed with red background in error grid.
Once the check is completed, the ISE reagent pack Lot Number and Expiry date will be
displayed. After this, you system is ready for processing the batch run and other maintenance
activities.
ISE OFF
By default, the auto maintenance start-up actions are performed automatically at the beginning of the
day when the application is started first time. This is an automatic service action that does not
require manual intervention.
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When starting the Auto Maintenance activity, if dome is open ( Level 1 and
Level 2 ) then following warning message with alarm beep will be displayed
and error message will be reported in error display grid.
During Auto Maintenance when dome is open ( Level 2 ), ARM movement will
be stopped immediately when activity requiring ARM movement is still
pending and error will be reported in error display grid.
This operation can be initiated any time from the Auto Maintenance from the Maintenance screen:
See the following procedure to perform auto maintenance and shutdown operation manually:
1. Select Start-Up.
2. Click Start.
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These operation is initiated automatically when the analyzer and computer are
turned on for the first time each day.
1. Select Shutdown.
2. Click Start.
3. Put the required amount of cleaning solution on the mentioned reagent and sample
position, and then click OK. On clicking, the probe will check the level of wash solution. If
not enough wash solution found, it will abandon the operation.
2. Probe wash externally and internally with wash solution (automatic step).
3. ISE clean
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This screen displays the cuvette blank for the requested wavelength. Wavelength can be selected by
the pull-down option provided on the left side of the screen. The navigation buttons to view the cuvette
blanks for the next and previous wavelength. There is also a GRAPH button available, through which
the cell blank reading for particular wavelength can be viewed in a graphical format.
Present Absorbance: It is the absorbance of the cuvettes with air measured after the last run or
Rotor check.
Previous Absorbance: It is the absorbance of the cuvettes with air measured after the second last
run or previous rotor check.
All dirty cuvettes will be skipped and no sampling will be done in dirty
cuvette.
Graph: On clicking this button, the user can view a graphical format of present absorbance obtained
at different wavelengths and also can view the graph for previous absorbance. A comparison of both
graphs can be done using ALL option.
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The maximum and minimum acceptable value of the cuvette blank absorbance can be set in the
Settings > System Parameter menu. If the absorbance of the cuvette blank exceeds the set
maximum blank absorbance, then that particular cuvette absorbance is indicated by Red font color.
On the other hand, if the absorbance of the cuvette blank is below the minimum acceptable
absorbance, then it is indicated by Blue font color.
The values on the cuvette blank value table display should be between minimum and maximum cell
blank range.
This screen shows the list of maintenance activities performed during the selected period with details
such as its status and source from which the activity was initiated.
The system records details like which activity is performed on what date, what was its source, and
what was the status.
Maintenance logs are extremely useful for troubleshooting purpose, as they provide a record of all
activity performed on the system and may shed light on hard-to-spot symptoms.
System keeps records of maintenance performed on the analyzer. To view the list, select date range
From and To.
List can be further filtered out according to Source, Activity and Status.
Source indicates the domain from where the maintenance activity is initiated. Sources can be
Maintenance screen, Shutdown screen, Application Start (start of application).
Activity indicates the type of maintenance operation performed.
Status indicates the status of activity, such as successful, unsuccessful, and performed.
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6.3.13 Settings
Settings menu allows you to perform the following operations:
System Parameters
Carryover Pairs
Test Sequence
Re-run Flags
User Rights
Host Settings
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Parameters Description
Displays the default laboratory name which will appear as header in the printed
Laboratory Name patient reports. The default laboratory name can be edited through Master
menu. See section Add Laboratory for more details.
It is used to change the software user interface language. Default language of
Default Language
the software is English. See section Setting UI language for more details.
This drop-down list is used for selecting the clearing of the input screens such
as Patient Entry, upon Save operation. The available options are Yes, No, and
User Confirmation.
On selecting option Yes, the screen will be cleared upon Save.
Clear Screen
upon Save On selecting option No, the screen will not be cleared upon Save and will
display the saved data. Click on CLEAR button in the respective screen to
add new data.
On selecting option User Confirmation; every time upon Save, user will be
prompted to choose the option to clear the screen.
Tick this check box to if you want to displays the alert message which will be
Confirmation
displayed on performing any critical operation such as SAVE or DELETE.
Message
Default is checked.
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This drop-down list is used to select setting for test parameters. Three options
are available Open, Semi Closed and Closed.
If Open option is selected, all the inputs on the test parameter screen are
editable and also new tests can be added.
If Semi-Closed option is selected, only some of the inputs on the test
Open Channel
parameter screen are editable for the pre-defined tests. A new test can be
Test
added.
If Closed option is selected, the inputs on the test parameter screen are
non-editable. A new test cannot be added.
This option may be used to secure the Test Parameter screen and shall be
disabled in closed system.
RCT Temperature This field displays the RCT Temperature in C. This value is 37 C.
It is used to set the allowable fluctuation in RCT Temperature. Enter the range
between 0 and 0.5.
RCT Temperature During batch run, when the RCT temperature fluctuation is outside the specified
Range range, warning message “Temperature out of Range” is displayed on Status
Monitor, logged in Error Log. All the results (except ISE) in process will be
declared with @TMP flag.
RGT
This field displays the RGT Temperature in C. This value is 8 C.
Temperature
RGT Temperature It is used to set the allowable fluctuation in RGT Temperature. Default value is 4
Range C. Enter the range between 0 and 4.
This option is used to select the availability of SRGT Barcode. Default is ticked
(available).
When the barcode identification is not desired, un-tick this option & SAVE. In
Barcode Reader such case, in Patient Entry screen, the Barcoded option will be disabled and
entry of sample position is mandatory.
Also, Barcode Scan button in Status Monitor > Barcode Scan is not available.
Reagents should be defined manually from Utility > Reagent Position screen.
This option is used to select the availability of ISE.
ISE Module
When un-ticked, ISE options are not available for scheduling & for batch run.
Using this option Lithium (Li) test can be disabled or enabled. If this option is
Li in ISE ticked then Lithium is activated and Lithium results will be displayed when ISE is
performed.
Machine SR. NO. Enter the serial number of machine (analyzer).
Enter the Minimum Cell Blank Absorbance from -0.12 to 0.05. If the absorbance
Minimum Cell of the cell blank falls below this limit, then the color of the cuvette Absorbance
Blank value in the Maintenance > Cell Blank screen will change to Blue. Default
value is -0.12.
Enter the Minimum Cell Blank Absorbance from 0.1 to 0.35. If the absorbance of
Maximum Cell the cell blank falls above this limit, then the color of the cuvette Absorbance
Blank value in the Maintenance > Cell Blank screen will change to Red. Default
value is 0.35.
Specify the desired percentage to extrapolate the calibration graph to a
Extrapolation particular percentage. Value between 0 to 20% can be entered. If the value is 0,
the graph is not extrapolated. Extrapolation value is set to zero by default.
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Min QC Results Set the minimum QC points required for lab mean. Enter value between 1 to
For Lab Mean 999. Default value will be 20.
Using this screen, you can define the forbidden pair for a particular chemistry.
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Parameters Description
Contaminant Select the first contaminant chemistry.
(1st)Test
Contaminate Select the second chemistry that could get contaminated.
d (2nd) Test
System Select this check box to perform system wash. The user can select this option for a
Wash forbidden pair.
During system wash, the arm will be washed with internal DI water after picking up
contaminant test reagent and before picking contaminated test reagent.
When this check box is selected then remaining options Wash, Wash Cycles and
Wash Volume will be disabled.
Wash Select Reagent Wash or Detergent Wash, as appropriate.
Wash The default number of wash cycle is 1. This field is not editable.
Cycles
Wash Define the wash volume as specified.
Volume
1. Use “Test Sequence” option to define Test Processing Sequence. This sequence
will be followed during run while performing the tests of each Sample. This will
reduce the carryover effect.
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5. If you want to perform probe wash before and after performing a particular test,
then use
In the following screen, serial number 4, Reagent wash will be performed before
performing the test ASO.
In the following screen, serial number 4, Reagent wash will be performed after
performing the test ASO.
In the following screen, serial number 4 and 5, Reagent wash will be performed
before and after performing the test ASO.
Processing the sequence of the test(s) can also be set from this screen.
Tests can be arranged in sequence using the following four available options:
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This option is used to set the sequence of tests. Once the test display sequence is set, the test(s)
will appear in the specified sequence in the following screens:
Patient Entry
Reports
Search
The sequence of test can be displayed in alphabetical order (ascending and descending). Use
difference modes to set the order as per requirement.
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It also provides a drag-and-drop mechanism to let you directly rearrange the test in a sequence within
the grid.
This option is used to set the process sequence of photometric tests, before or during the run.
It is useful in avoiding contamination by forbidden pairs that may come together during the run.
In order to avoid the carry over between patients, use forbidden pairs program.
To set the test process sequence to dynamic process sequence, select option TEST PROCESS
SEQUENCE, tick on the adjoining checkbox USE DYNAMIC PROCESS SEQUENCE and then click
SAVE.
In Closed System, two options will be visible on selecting the TEST PROCESS
SEQUENCE option.
The closed channels tests and open channels tests are displayed in separate
sections.
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On selecting any of the option, tests assigned for each sample will be
processed according to the test sequence as defined in the Closed Channels
Tests grid and Open Channel Tests grid. See the following figure for more
details.
Copied test with Closed reagent in Test Parameter is non editable in the list of Test Process
Sequence of closed channel test.
Copied test with Open reagent in Test Parameter is editable in the list of Test Process Sequence
of open channel test.
For Particular Test if Open/Closed reagent is changed from Test Parameter >Test Details, then this
test will be displayed in Test Process Sequence list in respective section of open / closed channel
test based on the changed reagent type.
This option is used to set the sequence of test and calculated items to be printed on the patient
reports.
This option is used to set the sequence of profile to be printed on the patient reports in Profile format.
If a particular flag is de-selected, then auto-rerun will not be performed when the flag is issued along
with the result for that test, even though auto-rerun is selected for the test from Test Parameter
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screen.
Guest is the default user name with all user rights. See the following figure.
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Depending on your network type (Peer-to-peer or LAN), choose the appropriate communication mode
from the screen. They are:
RS 232C
TCP/IP
Select RS 232C, if the analyzer and PC is connected in peer-to-peer (through serial port).
Select TCP/IP, if the analyzer and PC is connected in LAN (Local Area Network).
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Checksum
Check Connection
CHECK CONNECTION: This button is used to check the communication between Host and analyzer
PC.
CLEAR RESULT QUEUE: On clicking this, button, the ongoing result data to LIS will be stopped.
HELP: This button displays the ASTM HOST help file in more details.
When this option is selected, the patient results, which are generated during the batch run will be
automatically sent to LIS.
When this option is selected, the control results, which are generated during the batch run will be
automatically sent to LIS.
When this option is selected, system will accept redo test action received from LIS and re-do the
tests for that sample.
When this option is selected, patient results sent to LIS will be displayed with associated sample
position number and group number.
During run, when the sample barcode is performed, MultiXL will query LIS for downloading test details
for the scanned samples. MultiXL will query either 1 sample or 5 samples at a time depending on the
is selected. Choose the appropriate option, after consultation with LIS vendor:
Single
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Multiple(Max 5 Samples)
6.3.13.6.6 Checksum
This option allows user to select the character encoding set for all checksum calculations. In order to
support data transmission in Russian and any Cyrillic language the checksum calculation needs to
be in UTF-8 encoding.
CHECK CONNECTION button will displays the current communication status with LIS.
CLEAR RESULT QUEUE button is used to stop the ongoing result data to LIS.
Shutdown MultiXL
Maintenance operation is a fixed set of automatic service actions which can also be performed
through Maintenance. See section Auto Maintenance for more details.
When this button is pressed, MultiXL is minimized and maintenance operation is started. Once the
auto maintenance operation is completed, MultiXL will be automatically turned off.
Make sure that the required amount of cleaning solution are placed at tray
position 4 and 6.
Before system shutdown, a progress bar may be displayed on the screen which
indicates that the archive operation is in progress.
In this operation, backup of MultiXL database and Log files (XLComLog,
STATUSMSG, ASTMComLog and all xls files) are automatically archived in the C:
XL-180
6-193 User Interface
1. Go to Monitor > Select Scan Pack > System Pack Details screen will get displayed. Refer
Scan Pack for details.
2. Keep the master calibration card in front of Test loader device and press Scan Pack > following
details will get displayed on the screen:
5. For invalid reagent code, calibration can not be loaded for that code and accordingly message will
get pooped up.
6. User can also load master calibration from Utility > Scan pack
7. After registered the master calibration, go to main screen QC/Calibration > Calibration>
8. Select the test form the test panel for which master calibration is loaded form the card.
9. Master calibration for that test will get displayed with the consumable details on the screen as
XL-180
User Interface 6-194
shown below;
10.Go to main screen> Patients> Master calibration- test will get displayed in test panel grid.
11. Go to Report > Calibration Monitor > Master calibration test will get displayed in the report.
XL-180
6-195 User Interface
6.3.16 Archive
The archive data is the process of moving patient results to separate data storage for long-term use.
Data archives consist of older patient data which can be used for future reference, if required. Data
archiving improves the performance of (Live) database with the following key benefits.
For archiving and restoring patient data, the Archive option will appear on the main menu as shown in
the following figure.
Initially, when the software is installed, this option is not visible. It appears only when the patient
results reaches to a specific limit. In this case, at specific time interval, software automatically
prompts the user to archive the data when it is necessary. Thereafter, this option will be always
visible.
It is mandatory to archive the data before starting the batch run when the patient
result reaches a specific limit (software shows alert message, as required).
Only Patient results will be archived. The Calibration, Control and Consumables
data will always remain in the (Live) Database. While archiving the patient
results, the required additional information such as Area, Location, Doctor,
Reference Range etc are copied to the separate data storage (Archive Database)
and available while reviewing archived results.
Archiving Data
Observations
XL-180
User Interface 6-196
On clicking, the archive process started and the status will be displayed on the status bar.
XL-180
6-197 User Interface
4. After completing the archive process, a message “Archived data successfully” will be
displayed on the screen.
XL-180
User Interface 6-198
2. Select the Archived List to View Reports, and then select the desired archive to connect to
archive database to view the reports.
3. Click OK
On clicking, a message will be displayed “Connection successful. You may view the Patient
Reports”.
During this time, only Reports, Search and Shut down menus are
available. Rest of the menus will not be accessible.
XL-180
6-199 User Interface
4. After connecting to achieve database, you will be able to connect to Live database again by
selecting Live record from the list and click on OK button.
6.3.16.3 Observations
When the archive database is connected, the patient data can be viewed only in the following screen:
Other main menu screens are not accessible for the user except the following screens:
Search
Reports
Archive
Shutdown
XL-180
Part
VII
7-2 Operation
7 Operation
This section gives you a detailed description of daily workflows and step-by-step information about
common procedures that you need to perform as part of your daily workflow.
Daily start-up
Daily routine
Also, this section tells you the basic sequence of operations during the sample analysis. See the
following sections for more details:
Sequence of operations
When the batch run is started, the entire operation can be divided into the following sequence.
2. Reagent 1 addition
These measurement points are referred to as M1Start, M1End, M2Start and M2End and can be given
a value between 1 and 34. See section Test Details for more details.
The absorbance readings can be obtained from the Utility > Reaction Curve screen.
XL-180
Operation 7-3
XL-180
7-4 Operation
This section tells you the daily start-up procedures which prepare your analyzer for the day.
Confirm that:
The DI water Can is filled with pure DI water and the pH of the water should be maintained at
7.0.
Rotor Placement
XL-180
Operation 7-5
2. Wipe the rotors light path area with soft tissue paper. Ensure that there are no stains or
remains of paper within light path area.
4. Index the rotor to match the locating holders and pin in the rotor mount. Place the rotor.
5. Ensure that rotor has entered rested completely on the rotor mount.
Ensure that the following checks are performed before ISE measurement:
Before performing measurement with the ISE unit, confirm that Electrode unit (Na, K, Cl, Li and
Reference electrodes) whose term of validity is not expired is installed.
The Reagent Pack is filled with sufficient Calibrant-A and Calibrant-B solution.
Cleaning was carried out at the end of the last ISE measurement.
The Calibrant-A is flowing from the side of sample port by executing of ISE purge.
In the following cases, ISE purge should be carried out 5 times or more:
Just after turning on the analyzer, 3-4 times of ISE purge should be carried out. All electrodes
should be fitted to the ISE module, otherwise the liquid of Calibrant-A is flooded into the inside of
analyzer. It may cause serious problem.
The external tanks of the system DI water & diluted waste are to be placed near the left-hand side
or rear side of the analyzer and to be connected to the analyzer with the corresponding tubes
which includes float sensors.
Just before measurement, the DI water can need to be filled with the DI water and the can for
diluted waste have to be empty.
The DI water should have a resistivity of more than 1 Mega Ohm-cm (or conductivity less than
1µS/cm). Also the pH of the DI Water should be maintained to 7.0.
XL-180
7-6 Operation
2. Once the verification is done, turn on the main power supply switch.
Before starting the main supply, make sure that the ON/OFF switches
available on the rear and right side of the instrument should be in OFF
state.
3. Turn on the primary switch that is provided on the back side of the analyzer.
4. Turn on the secondary switch provided on the right side of the analyzer. After turning on the
switch, all the assemblies initialize to its home position.
When the analyzer is already ON, the system goes through a series of automatic service
maintenance actions. Typically, these actions are performed before the work day begins,
so that the instrument is ready to use when you start work. No user action is required in
this process. See section Auto Maintenance for more details.
If required, maintenance actions can be performed any time through Maintenance screen.
The MultiXL software will start automatically and the login screen is displayed.
You now have access to the system, depending on your user access level.
XL-180
Operation 7-7
Make sure that the sample (tubes or cups) and reagent containers are not filled
with patient samples up to the top of the container. Filling the sample container
up to the top most rim can cause spillage of sample within the instrument. This
care has to be taken by the operator.
Defining samples
The SRGT tray can accommodate 5ml, 7 ml tubes or 2 ml cups on 10 fixed sample positions.
Also, maximum 15 flexible positions available on the outer ring of the tray which can be used to
place small reagent containers (20 ml) or can be programmed as sample positions.
See section Sample and Reagent Barcode Reader for applying barcode label on sample tube.
1. Place the sample tube on the appropriate position on the SRGT tray.
2. Open Patient Entry screen, and enter the following necessary details:
XL-180
7-8 Operation
For emergency samples, select Emergency option and follow the same steps given
under b.
Sample Type
Sample Vol Type
Area
Ref Doctor
Sample Remark
Container Type
Collection Date
Reg. Date
Analyst
Patient Name
Age
Category
Patient ID
Address (of Patient)
Telephone
Patient and Sample Remarks
Select required tests, calculated items and profiles from Tests grid.
5. Click on SAVE.
This will save the programmed patient details and presents a new screen for programming the
next patient where the sample ID and sample positions are automatically incremented if
option Barcode is unchecked.
Defining reagents
Necessary reagents, diluents and wash solutions for analysis are placed on
the SRGT tray. Always use clean and dry rotor for sample run.
Before doing the analysis, place the necessary reagent and wash solution on the reagent tray.
Stick the barcode labels on the flat side of the reagent bottles and perform barcode scan
operation through Status Monitor. See section Barcode Scan for more details.
The analyzer will scan the reagent bottles and automatically detects and save the details (like
Reagent position number, lot number, Expiry date etc) related to the reagents placed in the
reagent bottles. Those details are saved and can be viewable on appropriate screen.
If the reagents are not having the lot details, it can be defined through the Consumable screen.
XL-180
Operation 7-9
Condensation can take place on the walls of the SRGT tray, near the reagent
bottle neck or on the barcode label due to the reagent cooling mechanism. If
condensation is present, then remove it using a dry tissue/paper.
If the reagent bottles are barcoded, then the analyzer identifies the reagents bottles
automatically and updates the positions of the barcoded reagent bottles placed on the SRGT
tray when the reagent barcode scan is performed.
3. Select the appropriate group number from the Group drop-down list.
On clicking, the available reagents will be scanned and the barcode id will be displayed on
the Reagent Barcode grid.
Column Reagent Barcode generally shows the barcode number read from bottle.
In some cases, instead of barcode number, following content may be displayed in this
column.
XL-180
7-10 Operation
“Checksum Mismatch”: When the checksum digit does not match the calculated
checksum of the bar-code digits.
“Unknown-barcode”: When the digits read are not as per required format or less than
18 digits are read.
“RGT Code Unknown“: When the Reagent Code is not found in the list of Reagents
in Consumables screen.
“-“: Reagent position is manually defined through Utility > Reagent Position screen.
Reagent(s), their position, Lot number and Expiry date is registered in the system for
the barcoded bottles.
This updated information is available in the Utility > Reagent Position screen.
The Barcode Scan button on the Status Monitor > Barcode Scan screen and
Barcode Scan option under Pre-run Options will not be available in case, the
options Barcode Reader are de-selected (un-ticked) from the Settings > System
Parameters screen.
Reagent Barcode Scan is mandatory in closed system, however, if the Reagent
Barcode option is de-selected (unticked) from the Settings > System
Parameters screen, then user can proceed with earlier scanned barcoded
reagent bottles.
5. Alternatively, a batch run can be started with Barcode Scan as a predecessor as follows.
6. Select (tick) Barcode Scan option from the Pre-run Options (at the top right hand corner)
in Status Monitor > Sample Tray screen. Click on start (batch) run button. Reagent tray
and Sample tray will be (barcode) scanned first and barcode information is updated
automatically in the system, before starting the batch run.
7. Batch run will start only if the reagent positions are available / known for all the test(s)
scheduled in the selected group.
Non barcoded reagent bottles have to be defined manually through Reagent Position screen
in Utility.
XL-180
Operation 7-11
3. Select the required position to be defined, from the Position list or select the required
position from the screen.
6. Select the appropriate bottle type from the Bottle Type list.
7. Select the reagent available lot number from the Lot No. list (Optional).
XL-180
7-12 Operation
9. Reagent details will be added for the selected position and displayed in the grid on the
screen. See figure as shown in the following page.
XL-180
Operation 7-13
The Rgt Vol(ml) column will show 0.00 ml at the time of definition, and it will
be updated after Reagent Volume Scan or at the first aspiration during run.
Starting analysis
Rotor change
Cuvette tracking
2. Select the appropriate group no. and cuvette number, and then click on button.
In closed system, batch run will not be started, if user defined open channels
are more than the permitted limit
When click on button, a card expiry warning message will get displayed
with expiry details of open test counts if card is expiring soon. Click to close
the warning message.
XL-180
7-14 Operation
Make sure that the starting cuvette number in the Status Monitor
should be equal to or less than 118. You are not allowed to select the
starting cuvette greater than the specified.
Make sure that Rotor is present on the RCT tray. If the rotor is not
present, a warning message will be displayed and the batch run will
not start.
When starting the batch RUN ,if dome is open ( Level 1 and Level 2 ) then pre
run activities will not be started and error message with alarm beep will be
displayed in error display grid.
During pre RUN activities, if dome is open ( Level 2 ) then all activities which
required ARM movement will be stopped immediately and error will be
reported in error display grid. Also further sampling will be paused.
3. Before starting the run, it is recommended to close all the running applications from the
computer as it may effect the execution of the programmed tests. The following warning
message will be displayed along with the list of applications, if any other application is running
in background.
XL-180
Operation 7-15
4. On start of the run, a confirmation message will be displayed asking about the rotor change or
not.
If you click "Yes", the "Rotor warming up" window will be displayed and the cuvette number
will be restored to number 1.
If selected "No", then run will start from the selected cuvette number. In this case, the warm-
up window will not be displayed, only if user has not manually changed the cuvette number
from cuvette drop down list. Refer section Rotor Change in more details.
If current selected run requires more number of cuvettes than available on the rotor, the
following message will be displayed on the screen.
XL-180
7-16 Operation
5. Once the confirmation of rotor change is received, “Rotor warming up” window will be
displayed. During this warm up, pre-run sequence of operation like Barcode Scan (if selected),
Reagent level scan (if selected), and Syringe priming and ISE calibration operations will be
performed.
During ISE calibration, the calibration values for each electrode (Na, K, Cl, Li) are checked. If
the values are in range, the run will proceed. ISE Calibration fails if the values are not in
range. In such case, system performs further action, as defined by user in System Parameter
Screen.
6. As soon as the pre-run operation is completed, the work list screen may be displayed if:
7. If all reagents are present with sufficient volume and the rotor warm up is over, run will proceed
for Auto Span. The message for Auto Span started will appear on the Status Monitor.
In the auto span, the gain value for a single cuvette for all the wavelengths is checked. If the
difference of gain is within the acceptable limit, then the gain values will be saved and the run
starts.
In case, if the gain is not within the range, the auto span operation is again performed to re-
validate the gain for the next available cuvette (to avoid dirty cuvette and incorrect cell blank
values). Again if the gain values received are not within the range, then the run will be aborted
and the error message will be displayed in the error grid.
8. Once the auto span is completed, instrument will initialize itself and batch run will start.
Once the run starts RCT and RGT temperature are displayed. If the RCT / RGT temperature
is within range specified in Settings > System Parameters option, the temperature is
XL-180
Operation 7-17
displayed in black color. When the temperature rises / falls out of the range, then it is
displayed in Red color.
Indication of RCT and RGT temperature will be displayed on the Status Monitor > SAMPLE
TRAY.
9. Start time of the run is displayed at top left corner of the screen.
During run, the progress of the measurement is displayed at the right hand side of the
screen. Just below the grid, a Detail button is available, which is used to see the detail cycle
map of the current/latest batch run.
The Details button is disabled at the start of MultiXL application. It is enabled only when the
cycle map data is recorded during the current run and available throughout the current
session of MultiXL application.
10.Results are displayed in the result grid and errors if any are displayed in Error grid at the
bottom of the screen.
When all the results are declared, the message will be popped up with beep sound indicating that the
Rotor needs to be changed. See figure as shown below.
To continue with the run,Open the dome > change the Rotor > Close the dome > and click on Yes
button. On clicking No, the run will be stopped.
XL-180
7-18 Operation
During run, the sample processing can be interrupted and resumed manually, if required. Following
button are provided on the Status Monitor > Sample Tray screen:
Use button to stop the run immediately. On clicking, all the assemblies initialize.
Use button to pause the sampling. If it is clicked, the processed result will be given out
and displayed on the result grid.
During run, the user can monitor the online reaction curve for the test. See section Reaction Curve
for more details.
During run, pending tests / mask tests can be re-schedule by clicking on the free space near the
sample positions. On clicking, the WorkList screen is again displayed, using which the tests can
be selected and then RE-SCHEDULE button can be clicked. (Pending / Mask tests can be
XL-180
Operation 7-19
scheduled only if the reagent and test details are available). See section Work List for more
details.
During run, emergency patients can be added from the Patient Entry screen by selecting the
option of ‘Emergency’ for that particular patient, entering the sample details and patient details.
During run, normal patients can be added from the Patient Entry screen, entering the sample
details and patient details.
During run, non-barcode reagents can be added from Reagent Position screen on empty reagent
positions. See section Defining non barcoded reagent bottles for more details.
After the end of the batch run, probe will be automatically washed by wash
In case, if wash solution is not defined or not found on the tray, then the probe will be washed by
the DI water indicating user by a warning message at the start of the run “Wash solution is not
found on the system. Probe wash shall be performed using DI water at the completion of the
RUN”.
During run, if error code 44 is encountered, then the batch run is stopped.
During run, the reagent will be aspirated from the reagent (bottle) position having
the nearest expiry date.
In case of multiple reagent bottles having the same expiry date, the reagent will be
aspirated in the order of position.
After the completion of the first batch run, the position of the last sensed in used
reagent bottle will be memorized. On starting the next batch, the previously sensed
reagent bottle position will be used for aspiration.
In case of multiple reagent positions, when volume of the first reagent reaches to dead
volume, then that test will be moved to pending list and the reagent aspiration starts from
next available reagent bottle.
In case of last available reagent bottle, if sampling continues till the reagent is absent, then
the remaining schedule of the test will be added in the pending list. In this case, user needs
to add new reagent bottles through Add Sample/Reagent button.
In closed system, during run, reagent bottle will get discarded after
consuming factory filled reagent volume.
XL-180
7-20 Operation
When froth is sensed while first reagent aspiration, then that test will move to pending list.
If froth is sensed in three consecutive reagent aspirations, then that reagent bottle position will be
deactivated and the associated test will move to pending list.
During run, when the froth is sensed in sample tube, following action can be performed:
When froth is sensed while first sample aspiration, then that particular test from the sample will
move to pending list.
If froth is sensed, for three consecutive sample aspirations, then all the tests associated with that
sample will move to pending list.
Schedules
If control interval is defined, control schedules will be sent between patient samples
according to the control interval defined in Test Parameters screen.
After the run, for a test if control interval is defined, control schedule for that test will not be
cleared off.
The number of cuvettes that have been used will be saved on the disc at the end of run or at the
completion of run.
Next time when you start the run, starting cuvette will be automatically set to next to the last used
cuvette.
On start of run, the software will display a message asking whether you have changed the rotor on
the instrument or not. If user clicks Yes then the used cuvettes should be reset to 0 and run will be
started from cuvette number 1, else run starts from the next available cuvette after the last used
cuvette number.
XL-180
Operation 7-21
If the run completes normally, it should reclaim the cuvettes passed during wait time till the result
declaration i.e. if there are 5 tests scheduled and run was started from cuvette 1 then on completion
of run, next run should start from cuvette no 7(5(for Tests) +1(Auto span) + 1 =7).
Dirty cuvette (cell blank) should be declared based on min/max limits in System Parameter screen.
Cell blank declaration is based on air blank reading of the cuvette before putting reagent.
3. Choose the appropriate option from the shutdown screen. See section Shutdown for more
details.
XL-180
Part
VIII
Error Handling 8-2
8 Error Handling
All the mechanical movements are controlled and monitored by the computer. When a problem
arises, the computer becomes aware of it and generates the visual error message to call the
operator's attention.
In the event of the problem that may affect the performance of the analyzer, the sampling stop or
emergency stop will be executed. In the case of sampling stop mode, the analyzer carries on and
completes the processing of the sample that is not affected by the problem. In the case of problem
that may affect the entire measurements of sample, the emergency stop will be executed.
Error recovery is an ability of software or equipment in which the errors will be automatically
recovered without affecting the sample run. During run, when the error is encountered, system will
first identify whether the current error falls under error recovery category or not. If yes, then the
system will initiate the recovery for that particular error, without stopping the run. The test affected
due to this error shall be moved to pending when processing moves to the next sample. In case, if
error is not recovered, then the run will be stopped. Each error that can be recovered shall be
attempted two times in that batch run. Third occurrence of the same error will not be recovered and
lead to final action designed for that error. Possible errors which come under auto error recovery
category and their remedial actions for all error conditions are listed in section List of errors.
Error Log screen will displays all the errors occurred on the analyzer during the test run or service
check operation. This data is generally useful for servicing/diagnostic purposes.
Problem may arise, which is not monitored by the computer. Any alarm message may not be
indicated on the display for such a problem. Such a problem includes abrasion of parts, leakage in
the sampling system, etc. When this type of problem occurs, decide whether the processing of
sample is carried on or the measurement is terminated, considering that such problem may result in
damage to the analyzer or erroneous outcome of measurements.
Flag list
List of errors
XL-180
8-3 Error Handling
XL-180
Error Handling 8-4
XL-180
8-5 Error Handling
Arm 15 @R1 Arm Down Arm VOD Switch OFF and Yes
error - opto & arm then switch ON the
Reagent 1 opto instrument. Check if
position Interface the error comes
card and its again
connector Remove the cover
Probe goes of the sample arm
down but and check and
doesn’t find clean obstacle opto
LLS signal Check the Arm
due to assembly
problem in If still it is giving
LLS card or error, call Service
its connector Engineer
Probe
assembly
XL-180
Error Handling 8-6
XL-180
8-7 Error Handling
Arm 19 @R1 Arm Down Arm VOD Switch OFF and Yes
error - opto & arm then switch ON the
Trough position, arm instrument. Check if
during up/down and the error comes
reagent 1 rotation opto again
operation Interface Remove the cover
card and its of the sample arm
connector and check and
Probe clean obstacle opto
assembly. Check the Arm
Up/down assembly
and rotation If still it is giving
stepper error, call Service
motor and its Engineer
connections
Arm 1A !R1 Arm VOD VOD Opto Check the arm If same
error – Sensor alignment in reagent is
Reagent VOD [Service Check]. If it present in
Pos. connectors is hitting at the next
edge, then align the available
Arm position probe using the position,
in Reagent calibrate facility. then that
tray at R1 particular
position Remove the cover
of the arm and test will be
check and clean moved to
VOD opto pending list
and
Go to Service sampling
Check: Arm Menu. continues
Click on <Initialize> from the
button. Push the next
probe gently to cut available
the VOD opto so reagent
that VOD Error will position.
be generated and
Arm initializes. In case, if
reagent is
If the initialization or not present
VOD generation or absent,
fails, call the all
Service Engineer. associated
tests will
moved to
pending
list. Use
Work List
button in
Status
Monitor
screen to
reschedule
the pending
tests.
XL-180
Error Handling 8-8
XL-180
8-9 Error Handling
Go to Service
Check: Arm Menu.
Click on <Initialize>
button. Push the
probe gently to cut
the VOD opto so
that VOD Error will
be generated and
Arm initializes.
If the initialization or
VOD generation
fails, call the
Service Engineer
Arm 1C !R1! Arm VOD VOD Opto Check the arm Yes
error - Sensor alignment in
Trough The [Service Check]. If it
during connectors is hitting at the
Reagent 1 edge, then align the
operation probe using the
calibrate facility.
Remove the cover
of the arm and
check and clean
VOD opto
Go to Service
Check: Arm Menu.
Click on <Initialize>
button. Push the
probe gently to cut
the VOD opto so
that VOD Error will
be generated and
Arm initializes.
If the initialization or
VOD generation
fails, call the
Service Engineer
XL-180
Error Handling 8-10
problem reagent is
not present
or absent,
all
associated
tests will
moved to
pending
list. Use
Work List
button in
Status
Monitor
screen to
reschedule
the pending
tests.
XL-180
8-11 Error Handling
XL-180
Error Handling 8-12
Service Engineer
XL-180
8-13 Error Handling
XL-180
Error Handling 8-14
Arm 25 @R2 Arm Down Arm VOD Switch OFF and Yes
error - opto & arm then switch ON the
Reagent 2 optos instrument. Check if
position Interface the error comes
card and its again
connector Remove the cover
Probe goes of the sample arm
down but and check and
doesn’t find clean obstacle opto
LLS signal Check the Arm
due to assembly
problem in If still it is giving
LLS card or error, call Service
its connector Engineer
Probe
assembly
XL-180
8-15 Error Handling
XL-180
Error Handling 8-16
Arm 29 @R2 Arm Down Arm VOD Switch OFF and Yes
error - opto & arm then switch ON the
Trough optos instrument. Check if
during Interface the error comes
Reagent 2 card and its again
operation connector Remove the cover
Probe goes of the sample arm
down but and check and
doesn’t find clean obstacle opto
LLS signal Check the Arm
due to assembly
problem in If still it is giving
LLS card or error, call Service
its connector Engineer
Probe
assembly
XL-180
8-17 Error Handling
XL-180
Error Handling 8-18
XL-180
8-19 Error Handling
XL-180
Error Handling 8-20
Arm 2A !R2 Arm VOD VOD Opto Check the arm If same
error – Sensor alignment in reagent is
Reagent The [Service Check]. If it present in
Pos. connectors is hitting at the next
edge, then align the available
Sample arm probe using the position,
position in calibrate facility. then that
Reagent tray particular
at R2 Remove the cover
of the arm and that will be
position moved to
check and clean
VOD opto pending list
and
Go to Service sampling
Check: Arm Menu. continues
Click on <Initialize> from the
button. Push the next
probe gently to cut available
the VOD opto so reagent
that VOD Error will position.
be generated and
Arm initializes. In case, if
reagent is
If the initialization or not present
VOD generation or absent,
fails, call the all
Service Engineer associated
tests will
moved to
pending
list. Use
Work List
button in
Status
Monitor
screen to
XL-180
8-21 Error Handling
reschedule
the pending
tests.
Arm 2C !R2! Arm VOD VOD Opto Check the arm Yes
error - Sensor alignment in
Trough The [Service Check]. If it
during connectors is hitting at the
Reagent 2 edge, then align the
operation Sample arm probe using the
position in calibrate facility.
Trough
during Remove the cover
Reagent 2 of the arm and
operation check and clean
VOD opto
Go to Service
Check: Arm Menu.
Click on <Initialize>
button. Push the
probe gently to cut
the VOD opto so
that VOD Error will
be generated and
Arm initializes.
If the initialization or
VOD generation
fails, call the
Service Engineer
XL-180
Error Handling 8-22
XL-180
8-23 Error Handling
tests.
XL-180
Error Handling 8-24
XL-180
8-25 Error Handling
Service Engineer
XL-180
Error Handling 8-26
XL-180
8-27 Error Handling
XL-180
Error Handling 8-28
XL-180
8-29 Error Handling
XL-180
Error Handling 8-30
XL-180
8-31 Error Handling
XL-180
Error Handling 8-32
XL-180
8-33 Error Handling
XL-180
Error Handling 8-34
Arm 352 @S Arm Down Arm VOD Switch OFF and Yes
Error - opto & arm then switch ON the
Dilution optos instrument. Check if
Cuvette Interface the error comes
card and its again
connector Remove the cover
Probe goes of the sample arm
down but and check and
doesn’t find clean obstacle opto
LLS signal Check the Arm
due to assembly
problem in Go to [Service
LLS card or Check: Arm] menu;
its connector Give <Initialize> and
Probe <Arm Up> Execute
assembly <Arm trough to R2
Cuvette> Execute
<Arm Down>
Execute commands
If still it is giving
error, call Service
Engineer
XL-180
8-35 Error Handling
Arm 353 @S Arm Down Arm VOD Switch OFF and Yes
Error - opto & arm then switch ON the
Dilution optos instrument. Check if
Cuvette Interface the error comes
card and its again
connector Remove the cover
Probe goes of the sample arm
down but and check and
doesn’t find clean obstacle opto
LLS signal Check the Arm
due to assembly
problem in Go to [Service
LLS card or Check: Arm] menu;
its connector Give <Initialize> and
Probe <Arm Up> Execute
assembly <Arm trough to R2
Cuvette> Execute
<Arm Down>
Execute commands
If still it is giving
error, call Service
Engineer
Arm 356 @S Arm Down Arm VOD Switch OFF and Yes
Error - opto & arm then switch ON the
Dilution optos instrument. Check if
Cuvette Interface the error comes
card and its again
connector Remove the cover
Probe goes of the sample arm
down but and check and
doesn’t find clean obstacle opto
LLS signal Check the Arm
due to assembly
problem in Go to [Service
LLS card or Check: Arm] menu;
its connector Give <Initialize> and
Probe <Arm Up> Execute
assembly <Arm trough to R2
Cuvette> Execute
<Arm Down>
Execute commands
If still it is giving
error, call Service
Engineer
XL-180
Error Handling 8-36
Arm 357 @S Arm Down Arm VOD Switch OFF and Yes
Error - opto and then switch ON the
Dilution arm optos instrument. Check if
Cuvette Interface the error comes
card and its again
connector Remove the cover
Probe goes of the sample arm
down but and check and
doesn’t find clean obstacle opto
LLS signal Check the Arm
due to assembly
problem in Go to [Service
LLS card or Check: Arm] menu;
its connector Give <Initialize> and
Probe <Arm Up> Execute
assembly <Arm trough to R2
Cuvette> Execute
<Arm Down>
Execute commands
If still it is giving
error, call Service
Engineer
XL-180
8-37 Error Handling
XL-180
Error Handling 8-38
XL-180
8-39 Error Handling
Arm 3A !S Arm VOD VOD Opto Check whether the When this
error - Sensor selected option is error
Sample The tube and instead of occurs, all
Pos. connectors tube a cup is placed the tests
Check the Arm associated
Sample arm with that
position in alignment in
Sample tray [Service Check]. If it sample will
is hitting at the moved to
edge, then align the pending
probe using the list. Use
calibrate facility. Work List
button in
Remove the cover Status
of the sample arm Monitor
and check and screen to
clean VOD opto reschedule.
Go to Service
Check: Arm Menu.
Click on <Initialize>
button. Push the
Probe gently to cut
the VOD opto so
that VOD Error will
be generated and
Arm initializes.
If the initialization or
VOD generation
fails, call the
XL-180
Error Handling 8-40
Service Engineer
Arm 3A2 !DILN Arm VOD VOD Opto Check whether the No
Error - Sensor selected option is
Dilution The tube and instead of
Cuvette connectors tube a cup is placed
Arm 3A3 !DILN Arm VOD VOD Opto Check whether the No
Error - Sensor selected option is
Dilution The tube and instead of
Cuvette connectors tube a cup is placed
XL-180
8-41 Error Handling
Arm 3A6 !DILN Arm VOD VOD Opto Check whether the No
Error - Sensor selected option is
Dilution The tube and instead of
Cuvette connectors tube a cup is placed
Arm 3A7 !DILN Arm VOD VOD Opto Check whether the No
Error - Sensor selected option is
Dilution The tube and instead of
Cuvette connectors tube a cup is placed
XL-180
Error Handling 8-42
XL-180
8-43 Error Handling
Arm 3B2 DILN! Arm VOD VOD Opto Check the arm No
Error - Sensor alignment in
Cuvette The [Service Check]. If it
connectors is hitting at the edge
, then align the
Sample arm probe using the
position in calibrate facility.
Dispense
cuvette Remove the cover
XL-180
Error Handling 8-44
Arm 3B3 DILN! Arm VOD VOD Opto Check the arm No
Error - Sensor alignment in
Cuvette The [Service Check]. If it
connectors is hitting at the edge
, then align the
Sample arm probe using the
position in calibrate facility.
Dispense
cuvette Remove the cover
of the arm and
check and clean
VOD opto
Go to Service
Check: Arm Menu.
Click on <Initialize>
button. Push the
probe gently to cut
the VOD opto so
that VOD Error will
be generated and
Arm initializes.
If the initialization or
VOD generation
fails, call the
Service Engineer
XL-180
8-45 Error Handling
Arm 3B6 DILN! Arm VOD VOD Opto Check the arm No
Error - Sensor alignment in
Cuvette The [Service Check]. If it
connectors is hitting at the
edge, then align the
Sample arm probe using the
position in calibrate facility.
Dispense
cuvette Remove the cover
of the arm and
check and clean
VOD opto
Go to Service
Check: Arm Menu.
Click on <Initialize>
button. Push the
probe gently to cut
the VOD opto so
that VOD Error will
be generated and
Arm initializes.
If the initialization or
VOD generation
fails, call the
Service Engineer
XL-180
Error Handling 8-46
Arm 3B7 DILN! Arm VOD VOD Opto Check the arm No
Error - Sensor alignment in
Cuvette The [Service Check]. If it
connectors is hitting at the
edge, then align the
Sample arm probe using the
position in calibrate facility.
Dispense
cuvette Remove the cover
of the arm and
check and clean
VOD opto
Go to Service
Check: Arm Menu.
Click on <Initialize>
button. Push the
probe gently to cut
the VOD opto so
that VOD Error will
be generated and
Arm initializes.
If the initialization or
VOD generation
fails, call the
Service Engineer
Arm 3C !S! Arm VOD VOD Opto Check the arm Yes
error - Sensor alignment in
Trough The [Service Check]. If it
during connectors is hitting at the
Sample edge, then align the
operation Sample arm probe using the
position in calibrate facility.
Trough
during Remove the cover
sample of the arm and
operation check and clean
VOD opto
Go to Service
Check: Arm Menu.
Click on <Initialize>
button. Push the
probe gently to cut
the VOD opto so
that VOD Error will
be generated and
Arm initializes.
If the initialization or
VOD generation
fails, call the
Service Engineer
XL-180
8-47 Error Handling
XL-180
Error Handling 8-48
XL-180
8-49 Error Handling
XL-180
Error Handling 8-50
aspirate/dispense
movement fails, call
Service Engineer
SRGT tray 71 @SRGT SRGT Position opto Switch OFF the Yes
Initialize assembly of analyzer; Rotate
Rotational RGT tray RGT by hand and
error Stepper make sure that
motor and its nothing is
connections obstructing the
rotation
Interface
card and its Then, switch ON the
connector instrument; Go to
[Service Check:
Reagent Tray]; Give
<Initialize>
command.
If initialization fails,
call Service
Engineer
SRGT tray 72 @SRGT SRGT Position opto Switch OFF the Yes
Rotational assembly of analyzer; Rotate
error RGT tray RGT by hand and
Stepper make sure that
motor and its nothing is
connections obstructing the
rotation
Interface
card and its Then, switch ON the
connector instrument; Go to
[Service Check:
Reagent Tray]; Give
<Initialize>
command.
If initialization fails,
call Service
XL-180
8-51 Error Handling
Engineer
SRGT tray 75 @SRGT SRGT Position opto Switch OFF the Yes
Rotational assembly of analyzer; Rotate
error during RGT tray RGT by hand and
R2 Stepper make sure that
operation motor and its nothing is
connections obstructing the
rotation
Interface
card and its Then, switch ON the
connector instrument; Go to
[Service Check:
Reagent Tray]; Give
<Initialize>
command.
If initialization fails,
call Service
Engineer
SRGT tray 76 @SRGT SRGT Position opto Switch OFF the Yes
Rotational assembly of analyzer; Rotate
error during RGT tray RGT by hand and
Sample Stepper make sure that
operation motor and its nothing is
connections obstructing the
rotation
Interface
card and its Then, switch ON the
connector instrument; Go to
[Service Check:
Reagent Tray]; Give
<Initialize>
command.
If initialization fails,
call Service
Engineer
XL-180
Error Handling 8-52
SRGT tray 78 @SRGT SRGT ARM assembly Make sure that arm No
rotational UP opto & assembly is not
error- Due Direction opto. down in RGT tray
to arm down during service
in Tray check for reagent i.e
during R2 service command
aspiration RGT initialize
RGT tray rotates
to “X” position. If
arm assembly
is not down then
check up opto &
direction opto
signal.
Check opto
connectors are
connected properly
or not.
SRGT tray 7A @SRGT SRGT Tray ARM Make sure that arm No
rotational assembly assembly is not
error- Due UP opto & down in RGT tray
to arm down Direction during service
in Tray opto. check for reagent i.e
during service command
Sample RGT initialize
aspiration
RGT tray rotates
to “X” position. If
arm assembly
is not down then
check up opto &
direction opto
signal.
Check opto
connectors are
connected properly
or not.
XL-180
8-53 Error Handling
SRGT tray 85 @SRGT SRGT ARM assembly After completing the Yes
Interlock UP opto run, Emergency stop is
Error - Due automatically executed
to Arm up and all assemblies
Error at R2 initializes.
position
SRGT tray 8F @SRGT SRGT ARM assembly Make sure that arm No
Interlock UP opto assembly is not
Error down in RGT tray
during service
check for reagent i.e
service command
RGT initialize
RGT tray rotates
to “X” position. If
arm assembly
is not down then
check up opto &
direction opto
signal.
Check opto
connectors are
connected properly
or not.
XL-180
Error Handling 8-54
XL-180
8-55 Error Handling
SRGT tray 86 @SRGT SRGT ARM assembly After completing the Yes
Interlock UP opto run, Emergency stop is
Error - Due automatically executed
to Arm up and all assemblies
Error at R1 initializes.
position
SRGT tray 87 @SRGT SRGT ARM assembly After completing the Yes
Interlock UP opto run, Emergency stop is
Error - Due automatically executed
to Arm up and all assemblies
Error at initializes.
Sample
position
XL-180
Error Handling 8-56
XL-180
8-57 Error Handling
signal.
Check opto
connectors are
connected properly
or not.
XL-180
Error Handling 8-58
<Arm trough to R2
Cuvette> Execute
<R2 Cuvette to
Trough> Execute
commands
If the initialization or
rotation fails, call
Service Engineer
XL-180
8-59 Error Handling
XL-180
Error Handling 8-60
XL-180
8-61 Error Handling
XL-180
Error Handling 8-62
XL-180
8-63 Error Handling
XL-180
Error Handling 8-64
Stirrer C7 @STR1 Stirrer Down Position opto Switch OFF the Yes
error - assembly of analyzer; Rotate
Cuvette stirrer stirrer by hand and
during Interface make sure that
Sample card and its nothing is
Stirring connector obstructing the
rotation.
Stepper
motor Then switch ON the
instrument; Go to
[Service Check:
Stirrer]; Give
<Initialize> and
<Trough to stirring
cuvette> Execute
<Stirrer Down> and
Execute <Stirrer
Up> then Execute
<Initialize>
If the initialization or
rotation fails, call
Service Engineer
XL-180
8-65 Error Handling
Check
Spartan
board
connections
Step loss in
Stepper
motor
Check
Spartan
board
connections
Step loss in
Stepper
motor
XL-180
Error Handling 8-66
XL-180
8-67 Error Handling
XL-180
Part
IX
9-2 Configuration
9 Configuration
This section describes step-by-step procedures for some common configuration tasks. You must
have the required user access level to perform these tasks.
Setting UI language
Access control
Create profile
For more information on setting the user access see section User Rights.
1. In the login screen, enter Guest in the Login ID textbox and click on the link “Click Here” as
shown in figure below.
On clicking, a text file is created which contains password details of the user and sends to
the location C:\MultiXLLOG. The following screen will be displayed.
2. Go to folder C:\MultiXLLOG, and send the generated text file, for example
‘ForgotPWD20110305.Txt’ to the service engineer. See figure as shown below.
XL-180
Configuration 9-3
3. Click OK to close.
List of Languages supported: English, Chinese, Italian, Spanish, Portuguese, Russian, French,
German, Polish and Czech.
2. Go to System Parameters screen, and click on the three dotted button available on the
Default Language parameter.
4. Select the desired language from the Set Language drop down list.
5. Click OK. The captions on the screen will appear in the selected language. Alternatively,
language can also be changed using F10 key from the keyboard.
Patient Entry
XL-180
9-4 Configuration
Reports
Search
Once the test display sequence is set, the tests will appear in the specified sequence.
4. Rearrange the tests as required using the buttons provided for sorting.
3. Click on the CLEAR button, and then enter the user name in the User Name field.
4. Now enter the type of user using User Type drop down list. Four options are available:
Super-User
User
Analyst
Doctor
XL-180
Configuration 9-5
A user defined with User Type as Analyst or Doctor will also appear in the list of
Analyst and Doctor respectively from Patient Entry screen.
On Panel
Address
City
State
Country
Zip Code
Telephone
Email ID
Login ID
New Password
Confirm Password
User must enter the details for the parameters that are marked with red asterisk.
6. Once all the data are entered, click on the SAVE button. This will create the user ID.
3. Click on the search button. On clicking, the HELP window will be displayed containing
the list of existing user IDs.
4. Now, select the required user name by double click and click EDIT button.
XL-180
9-6 Configuration
5. Check or uncheck the check boxes under column Full Access as per requirement, and click
SAVE to confirm. The settings will be saved for that user id.
User must replace the old password with the new password before saving the
settings.
XL-180
Configuration 9-7
3. Click on the search button. On clicking, the HELP window will be displayed containing
the list of existing user IDs.
4. Now, select the name of the user by double click and click EDIT button.
5. Now enter the old password, new password, and confirm password and then click SAVE to
confirm the settings.
6. If the user has forgotten the password, click on EDIT, select the FORGOT PASSWORD
check box and then enter the New Password and Confirm Password.
XL-180
9-8 Configuration
3. Click EDIT.
Port No.
Baud Rate
Parity
Data Length
Stop Bits
Make sure that baud rate, parity, data length and start bit settings entered in
the host computer should match with analyzer's PC.
On successful connection, connection between the LIS and host will be established, and
data will be saved.
XL-180
Configuration 9-9
IP Address
Port No.
Make sure that the port number entered in the host computer should match
with analyzer's PC.
On successful connection, connection between the LIS and host will be established, and
data will be saved.
XL-180
9-10 Configuration
Name of analyst
Name of laboratory
Name of manufacturer
Types of unit
Calculation formula
Instrument
4. Click on SAVE.
5. This will add the area name and displayed in the grid.
4. Click on EDIT.
6. Click on SAVE.
XL-180
Configuration 9-11
7. This will update the area name and displayed in the grid.
4. Click DELETE.
4. Click on SAVE.
5. This will add the doctor name and displayed in the grid.
4. Click on EDIT.
6. Click SAVE .
7. This will update the doctor's name and displayed in the grid.
4. Click DELETE.
XL-180
9-12 Configuration
4. Click SAVE.
5. This will add the analyst name and displayed in the grid.
4. Click EDIT.
6. Click SAVE .
7. This will update the analyst's name and displayed in the grid.
4. Click DELETE.
4. Click SAVE.
5. This will add the laboratory name and displayed in the grid.
XL-180
Configuration 9-13
4. Click EDIT.
6. Click SAVE .
7. This will update the laboratory's name and displayed in the grid.
4. Click DELETE.
4. Click SAVE.
4. Click EDIT.
6. Click SAVE .
XL-180
9-14 Configuration
7. This will update the manufacturer's name and displayed in the grid.
4. Click DELETE.
4. Click SAVE.
5. Click SAVE .
6. This will update the reference range and displayed in the grid.
4. Click DELETE.
XL-180
Configuration 9-15
To add a unit
4. Click SAVE.
To edit a unit
5. Click SAVE .
To delete a unit
4. Click DELETE.
To add a formula
4. Click SAVE.
5. This will add the calculation formula and displayed in the grid.
XL-180
9-16 Configuration
To edit a formula
5. Click SAVE .
6. This will update the calculation formula and displayed in the grid.
To delete a formula
4. Click DELETE.
4. Click SAVE.
5. This will add the instrument name and displayed in the grid.
4. Click EDIT.
6. Click SAVE .
7. This will update the instrument's name and displayed in the grid.
XL-180
Configuration 9-17
4. Click DELETE.
Data archiving improves the performance of (Live) database with the following key benefits.
For archiving and restoring patient data, the Archive option will appear on the main menu as shown in
the following figure.
Initially when the software is installed, this option is not visible. It appears only when the patient
results reaches to a specific limit. In this case, at specific time interval, software automatically
prompts the user to archive the data when it is necessary. Thereafter, this option will be always
visible.
It is advisable to archive the older patient results to separate data storage.
XL-180
9-18 Configuration
It is mandatory to archive the data before starting the batch run when the
patient result reaches a specific limit (software shows alert message, as
required).
Archiving Data.
Observations
1. Click on the Archive option from the main menu. following screen will be displayed
XL-180
Configuration 9-19
3. Select the Archive Patient Data option, and click OK,the archive process will start and the
status will be displayed as shown below
4. After completing the archive process, a message “Archived data successfully” will be
displayed on the screen.
1. Click on the Archive option from the main menu.Following screen will be displayed
XL-180
9-20 Configuration
3. Select the Archived List to View Reports option then select the desired archive to connect
to archive database to view the reports.
4. On clicking OK a message will be displayed “Connection successful. You may view the
Patient Reports”.
XL-180
Configuration 9-21
During this time, only Reports, Search and Shut down menus are available.
Rest of the menus will not be accessible.
5. After connecting to achieve database, user will able to connect to Live database again by
selecting Live record from the list.
9.7.3 Observations
When the archive database is connected, the patient data can be viewed only in the following screen:
Other main menu screens are not accessible for the user except the following screens:
Search
Reports
XL-180
9-22 Configuration
Archive
Shutdown
Add profile
Delete profile
2. Enter the profile name and profile report name in the respective text box.
3. Add the required tests by clicking on the test name from the Tests grid.
5. Once the profile is saved, the name appears in the Profiles grid.
3. Click Delete.
4. Click Yes.
XL-180
Part
X
10-2 Result Flags
10 Result Flags
Measurement result flags are printed out together with the measurement result. See the section Flag
List in more details.
1 # This flag is issued to indicate that the result obtained is from a rerun. This flag
is issued for all rerun results
3 F This flag is used to indicate that correlation correction has been used to
calculate the final result. That is, this flag is issued if in the equation Y = aX
+ b, a is not equal to 1 or b is not equal to zero.
4 -1SD This flag is issued with control results when the result is below 1SD limit
5 +1SD This flag is issued with control results when the result is above 1SD limit
6 -2SD This flag is issued with control results when the result is below 2SD limit
7 +2SD This flag is issued with control results when the result is above 2SD limit
8 -3SD This flag is issued with control results when the result is below 3SD limit
9 +3SD This flag is issued with control results when the result is above 3SD limit
10 NOCAL This flag is issued with patient or control result and indicates that the
calibration table is not available for result calculation. The calibration table
needs to be checked and corrected to calculate a result (e.g. calibration is
not present or number of standards provided for calibration is less than
required
11 ?SD This flag is issued with control results when the target Mean and SD values
have not been defined for the control in Consumables screen. Therefore, flags
such as “±1SD”, “±2SD”, “±3SD” cannot be given
12 V-D This flag is issued with patient results and indicates a Decreased volume run.
13 V-I This flag is issued with patient results and indicates a Increased volume run.
14 MONO This flag is issued with patient and control results when, for the concerned
test, the absorbance’s of the calibrators are not changing monotonically with
their respective concentration in the calibration table.
15 PD This flag is issued with patient and control results to indicate that the sample
was pre-diluted.
16 P* This flag is issued with patient and control serum results to indicate that
prozone (antigen excess) has occurred.
XL-180
Result Flags 10-3
17 TEC-H Upper technical limit violated. Measured value or absorbance slope is higher
than the set maximum technical limit. (Set Maximum limit to zero to cancel
the check for TEC-H flag.)
18 TEC-L Lower technical limit violated. Measured value or absorbance slope is lower
than the set minimum technical limit. (Set Minimum limit to zero to cancel
the check for TEC-L flag.)
19 RANGH 1. This flag is issued with patient and control results to indicate that the
absorbance of the sample is higher than the absorbance of the highest
concentration calibrator in the calibration table for an increasing reaction
direction test.
2. This flag is also issued with patient and control results if the absorbance of
the sample is lower than the absorbance of the highest concentration
calibrator in the calibration table for a decreasing reaction direction test.
20 RANGL 1. This flag is issued with patient and control results to indicate that the
absorbance of the sample is lower than the absorbance of the blank (or
lowest concentration calibrator) in the calibration table for an increasing
reaction direction test.
2. This flag is also issued with patient and control results if the absorbance of
the sample is higher than the absorbance of the blank (or lowest
concentration calibrator) in the calibration table for a decreasing reaction
direction test.
21 H Measured value is larger than upper limit set for normal value range for the
corresponding age, sample type and category.
22 L Measured value is smaller than lower limit set for normal value range for the
corresponding age, sample type and category.
23 CALC! Calculated Item is not calculated for any of the following reasons.
1. Denominator is 0 (zero) in the process of calculation for compensation.
2. The test to be used for Calculation Item has not been measured yet.
3. Any test to be used for Calculated Item has data/calibration alarms, such
as NOCAL
4. Any test to be used for Calculation Item errors (S*, R1* etc)
24 ABSLIM This flag is issued for End-Point chemistries and Rate chemistries when the
absorbance is beyond the Reaction Absorbance Limit set in Test Parameter.
For Rate-chemistries, this flag will be issued when Technical limit is set. In
this case, Extension Logic will not be applied.
25 PANL Low Panic value alarm. This flag is issued with a sample result to indicate
that the patient result is lower than the Lower Panic Limit programmed in Test
Parameter for the corresponding age, sample type and category.
26 PANH High Panic value alarm. This flag is issued with a sample result to indicate
that the patient result is higher than the Upper Panic Limit programmed in
Test Parameter for the corresponding age, sample type and category.
27 LINxx Linearity abnormal (checked only for Rate A and Rate B assays). When the
reaction during measurement points M2S and M2E is non-linear beyond the
set limit for linearity of reaction this flag is given and the percent linearity of
reaction is indicated by a two digit number xx after “LIN”.
XL-180
10-4 Result Flags
28 Lim0 This flag is applicable for Rate Chemistries, only during the extension logic
(Technical Limit is zero) and when Reaction Absorbance Limit is present
(non-zero). If there is no measurement point available for result calculation,
then this flag is issued and result will be “NA”.
29 Lim1 This flag is applicable for Rate Chemistries, only during the extension logic
(Technical Limit is zero) and when Reaction Absorbance Limit is present
(non-zero). If there is only one measurement point available for result
calculation, then this flag is issued and result will be “NA”.
30 Lim2 This flag is applicable for Rate Chemistries, only during the extension logic
(Technical Limit is zero) and when Reaction Absorbance Limit is present
(non-zero). If there are only 2 measurement points available for result
calculation, then this flag is issued.
31 ??? This flag is issued when the denominator becomes zero during calculation or
an overflow error occurs in logarithmic or exponential calculation.
32 Rgt Abs This flag indicates that the reagent 1 absorbance is lower than the
Min programmed Reagent Absorbance Min
33 Rgt Abs This flag indicates that the reagent 1 absorbance is greater than the
Max programmed Reagent Absorbance Max
34 @TMP This flag is issued for results other than ISE, when the RCT temperature was
out of range while the measurement was in process.
35 TO This flag indicates Time Out while receiving result from the machine.
36 Cal* This flag is issued with the patient and control results to indicate that the
results are being calibrated with previous calibration data.
37 EVH This flag is issued with the patient result when the result is higher than the
concentration of the highest calibrator and is calculated by extra-polating the
calibration curve on higher side.
Extrapolation % (maximum 20%) is set in system parameters.
38 EVL This flag is issued with the patient result when the result is lower than the
concentration of the lowest calibrator and is calculated by extra-polating the
calibration curve, upto zero.
Extrapolation % (maximum 20%) is set in system parameters.
40 S$ This flag is issued when the air bubble is sensed on sample position. On
occurrence of this error, the tests for that particular sample will be stopped
and go into pending list.
41 R1$ This flag is issued when the froth is detected on R1 position. On occurrence
of this error, the tests for that particular R1 position will be stopped and go
into pending list.
42 R2$ This flag is issued when the froth is detected on R2 position. On occurrence
of this error, the tests for that particular R2 position will be stopped and go
into pending list.
XL-180
Result Flags 10-5
43 W* This flag is issued with the result when there is a problem performing wash
(detergent or reagent) during carry over pair process.
44 COMM* This flag is issued with the result if any reading is missed out between the
measurement point (M1 Start and M2 Start) due to communication failure.
45 N! This flag is issued to patient results having a negative value. Negative results
can be sent to host and also for a re-run based on user selection. If "Print
Negative Result" checkbox is unchecked in System Parameters, then in this
condition, negative test result will be printed as zero in Patient Report and N!
Flag will be printed only if “Hide Flags” option is not selected during printing.
46 HV! This flag is issued when, during RUN the measured volume in the reagent
bottle is more than the specific capacity of that particular bottle type (small/
large).
47 LV! This flag is issued when, during RUN the measured volume in the fresh or
used reagent bottle is below the tolerance of last known level.
48 DA This flag is issued when, test affected due to dome opened abruptly (level 2)
and ARM movement is stopped.
49 ABS! This flag is issued when an Absorbance in a Reaction curve is above 3.0,
XL-180
Part
XI
Maintenance 11-2
11 Maintenance
This section provides the necessary and minimal maintenance procedures in order to ensure that the
analyzer operates correctly and provides the accurate measurement results.
The analyzer has been designed to require very little user maintenance compared to the other
analyzers of the same class. Regular cleaning and periodic maintenance as per the schedule keeps
the analyzer in good working condition without any trouble.
Daily Maintenance
Weekly Maintenance
Quarterly Maintenance
Annual Maintenance
Preventative Maintenance
Always use fresh DI water in clean and pre-washed Cans to prevent water from
contamination.
3 Clean the probe tip and stirrer paddle with tissue paper soaked in alcohol.
XL-180
11-3 Maintenance
7 Perform the photometer check and verify that the auto span check has passed
successfully. (Observe after 10 minutes warm-up).
8 Remove any condensation present on the walls of the SRGT tray, near the
reagent bottle necks or on the barcode label using a dry tissue.
9 Verify the reagent tray and reaction tray temperature after 10 minute warm up.
10 In case of ISE unit, ensure that there is enough CAL A and CAL B solution.
1 Remove and discard all Sample, Standard, and Controls cups or tubes from the
sample tray.
4 It is preferred that while shut down, user selects “Auto maintenance & Shut
down” option from the shut down window.
5 Turn off the main switch located on the right hand side of the analyzer (in case ISE
and if reagent cooling required, leave rear side switch and mains switch where
analyzer is connected on).
6 Remove any condensation present on the walls of the SRGT tray or near the
reagent bottle necks using a dry tissue.
Always use fresh DI water in clean and pre-washed Cans to prevent water from
contamination.
2 In case of ISE unit, ensure that there is enough CAL A and CAL B solution.
4 Clean the computer, trolley, monitor, keyboard and printer external surface.
XL-180
Maintenance 11-4
5 Clean the area around the analyzer, and discard any unwanted item. (Maintain
proper room cleanliness).
6 Clean the probe tip and stirrer paddle with tissue paper soaked in alcohol.
9 Perform an auto span check and note down the gain values for all the
wavelengths.
10 Perform a precision check and note down the %CV for an end point and
kinetic test.
11 Clean the barcode reader window in the piece of RGT base unit.
Always use fresh DI water in clean and pre-washed Cans to prevent water from
contamination.
2 Clean and fill the DI water can. Replace the filter in DI water can.
3 In case of ISE unit, ensure that there is enough CAL A and CAL B solution.
5 Clean the area around the analyzer, and discard any unwanted item (maintain
proper room cleanliness).
6 Clean the probe tip and stirrer paddle with tissue paper soaked in alcohol.
XL-180
11-5 Maintenance
12 Perform the auto span check and note down the gain values for all the
wavelengths.
13 Perform a precision check and note down the %CV for an end point and
kinetic test.
16 Perform an auto span check and note down the gain values for all the
wavelengths.
17 Carry out site verification for temperature, line voltage, electrical ground,
ventilation, external interferences, room lighting, and laboratory cleanliness
practice.
18 Make a detailed entry of the maintenance carried out and site verifications
performed in the error log book.
19 Clean PC hard disk for temp file like old communication log files.
Always use fresh DI water in clean and pre-washed Cans to prevent water from
contamination.
3 In case of ISE unit, ensure that there is enough CAL A and CAL B solution
7 Clean the area around the analyzer, and discard any unwanted item (maintain
proper room cleanliness).
9 Clean the probe tip and stirrer paddle with tissue paper soaked in alcohol.
XL-180
Maintenance 11-6
14 Perform the auto span check and note down the gain values for all the
wavelengths.
15 Perform a precision check and note down the %CV for an end point and kinetic
test.
18 Perform an auto span check and note down the gain values for all the
wavelengths.
19 Carry out site verification for temperature, line voltage, electrical ground,
ventilation, external interferences, room lighting, and laboratory cleanliness
practice.
20 Make a detailed entry in the error log book, of the maintenance carried out and
site verifications.
Average life of the Lamp is 1000 hours. Replacement of Lamp depends on its
usage and ON Time.
Average life of water filter is 3 months. Replacement of water filter depends on quality of DI water
used.
DI water pump has average life of around 4000 hrs. Depending on the use of the analyzer, DI water
pump may need periodic replacement.
XL-180
11-7 Maintenance
XL-180
Maintenance 11-8
5. Immerse the rotor in 3% nitric acid or Hydrochloric Acid solution and keep it for 5 minutes (in
case if deproteinization is required).
XL-180
11-9 Maintenance
9. Place the rotor in clean space by resting it on handles provided for lifting & allow drying at
room temperature.
1. Remove the reaction mixture from the rotor wells as per individual laboratory’s bio-hazardous
waste handling processes.
3. Immerse the rotor in a 5% wash solution (Erba XL Wash) for 3 minutes in ultrasonic cleaner.
Set the temperature from 35 °C to 37 °C.
XL-180
Maintenance 11-10
4. Remove the rotor from ultrasonic cleaner and rinse thoroughly with running water.
7.Place the rotor in clean space by resting it on handles provided for lifting & allow drying at room
temperature.
XL-180
11-11 Maintenance
The rotors must be rejected if they are noticeably deteriorated. The optical
status of a rotor can be verified by means of the Reactions rotor verification
utility on the Maintenance screen of MultiXL software.
The useful lifetime of each rotor depends drastically on its use and care.
5 STIRRER PADDLES
XL-180
Maintenance 11-12
2. Switch Off the analyzer, pull out the plug of power supply cable from its receptacle & check
the mains fuse inside the fuse cover.
3. Check that the circuit breaker of the power supply system to which the analyzer is connected
is not cut off
4. The resultant values obtained from measurements of a specific method are high for all
samples.
5. The resultant values obtained from measurements of a specific method are low for all samples.
11.7.3 High Resultant Values from a Specific Method for all Samples
2 Too high inside temperature of RCT Check the temperature shown in the Service
unit. Check > RCT Coils.
Call for service at our customer service
department when the indicated temperature
deviates from the specified value of 37 ±
XL-180
11-13 Maintenance
0.5ºC.
11.7.4 Low Resultant Values from a Specific Method for all Samples
1 Expiration of the term of validity of reagent. See the statement of virtues that comes
together with the reagent kit for its stability.
4 Too low inside temperature of RCT unit. Check the temperature shown in the Service
Check > RCT Coils.
Call for service at our customer service
department when the indicated temperature
deviates from the specified value of 37 ±
0.5ºC.
1 Expiration of the term of validity of See the statement of virtues that comes
reagent. together with the reagent kit for its stability.
4 Too low inside temperature of RCT unit. Check the temperature shown in the Service
Check > RCT Coils.
Call for service at our customer service
department when the indicated temperature
deviates from the specified value of 37 ± 0.5ºC.
XL-180
Maintenance 11-14
1. Preparation of reagent.
a) Was there any change of the reagent?
b) Is the term of validity of the prepared reagent still valid?
c) Was the reagent prepared according to the correct procedures?
d) Was the reagent prepared using fresh, non-bacteria contaminated and DI water or
appropriate diluent?
2. Preparation of QC sample.
a) Was the volume used for preparation correct?
b) Does the sample have been preserved as recommended?
c) Is the term of validity of the sample still valid?
d) Was the sample prepared using a pipette calibrated in terms of volume?
e) Is the term of validity of the sample lot still valid?
f) Was the sample prepared using appropriate diluent?
3. Preparation of calibrator.
a) Was there any change of the lot number?
b) Was the calibrator prepared using volume correctly?
c) Does the calibrator have been preserved as recommended?
d) Is the term of validity of the calibrator still valid?
e) Was the calibrator prepared using a pipette calibrated in terms of volume?
f) Was the calibrator prepared using appropriate diluent?
The further checks are requested to track down the cause referring to the following lists after the
above checks have been completed
XL-180
Part
XII
ISE Measurement (Optional) 12-2
It is placed on extreme left side of the chemistry analyzer. See section Left Side View.
All waste liquid are discharged into the external tank for high concentration waste liquid.
The module is completely self-contained. All the sample and calibrant positioning within the module
is controlled by an integral microprocessor, which assures reliable electrode operation and maximum
lifetime. The electrolyte measurement system’s microprocessor applies proprietary mathematical
algorithms to electrode output voltages, converting them to clinical units of mmol/L.
XL-180
12-3 ISE Measurement (Optional)
XL-180
ISE Measurement (Optional) 12-4
XL-180
12-5 ISE Measurement (Optional)
Technical Specification
Measurement Theory
Shutdown Procedure
ISE Calibration
Maintenance Schedule
Troubleshooting
Error Message
XL-180
ISE Measurement (Optional) 12-6
The flow-through electrodes use selective membrane tubing, specially formulated to be sensitive to
the respective ions. The potential of each electrode is measured relative to a fixed, stable voltage
established by the double junction Silver/Silver-chloride reference electrode. An ion-selective
XL-180
12-7 ISE Measurement (Optional)
electrode develops a voltage that varies with the concentration of the ion to which it responds. The
relationship between the voltage developed and the concentration of the sensed ion is logarithmic, as
expressed by the Nernst equation.
Calibrant A: It is used in both two-point and single-point calibrations for serum sample analysis.
Calibrant A is pumped into the sample entry port by the Calibrant A pump and then positioned in
front of the electrodes by the waste pump. Calibrant A solution is also used for Pump and Bubble
Calibration.
Calibrant B: It is used in two-point and single-point calibrations for urine sample analysis. Calibrant
B is pumped into the sample entry port by the Calibrant B pump and then positioned in front of the
electrodes by the waste pump.
Cleaning Solution: It is used once a day to prevent protein buildup on the electrodes and fluid path.
It must be used more frequently if the ISE Module performs greater than 50 sample measurements
per day. 100 µl of cleaning solution must be aspirated by the host analyzer from a sample cup on the
host analyzer and dispensed into the sample entry port. The sample cup must be covered to
eliminate evaporation.
Urine Diluent: It is required for the urine samples. Urine samples are diluted on-board by 10 times (1
part sample to 9 parts urine diluent) to perform urine measurement. The operator must keep the urine
diluent on the Reagent Tray
The ISE Urine sample is performed with 10X dilution during its first run. During ISE-rerun, the 3X and
15X dilutions may be performed, depending upon the flag attached to the result (based on increased
or decreased sample volume).
On receiving the result, the test will go for rerun on the following conditions
1. If the sample result is attached with PANH flag, then sample will go for rerun with normal dilution
that is 1:9 (10X). If the sample result is attached with RANGH flag, then the sample will go for
rerun with decreased sample volume that is 1:14 (15X) dilution.
2. After receiving the result for the sample replicates, if both the replicates are attached with different
flag that is RANGH (requiring decrease rerun) and RANGL (requiring increase rerun). But the
priority of RANGH is higher so this sample will go for a Re-run with decrease sample volume. The
XL-180
ISE Measurement (Optional) 12-8
number of replicates sent to Rerun will be the same as number of replicates sent during the 1st
(original) determination.
The software will display re-run result (after applying the volume
correction) for only those tests having flags that required re-run. The
Attach Rerun Flag (“#”) and Volume Increase/ Volume Decrease Flag (“V-
I”/ “V-D”) will be displayed after correcting the results. Flags H, L, PANH,
PANL , RANGH and RANGL will be applicable to ISE results.
2. Don't preserve the reagents such as or cleaning solution once they are dispensed to sample
cup.
4. When opening new bottle for a solution, don't mix remaining solution from the previous bottle
When the power to the analyzer needs to be turned off for a reason such as maintenance, follow the
procedure below to purge Calibrant-A solution in the path. Also refer to the procedure when turning
off the power for more than several hours, as it requires storage of the electrodes
1. If the laboratory plans to store the ISE module for a period greater than one week, during
which the analyzer will not be connected to power, the following steps should be
performed.
2. Before removing the electrodes, they should be cleaned using the cleaning solution and
then running 3 Purge A cycles from the Maintenance > ISE.
1. Depress the compression plate and remove all electrodes, including the reference electrode
from the ISE Module.
2. Place the Na+ and Cl- electrodes into individual sealed bags.
3. Reinsert the Reference Electrode flow path line with yellow flag, if available, and then put
into individual sealed bags.
XL-180
12-9 ISE Measurement (Optional)
1. Aspirate a small volume of Calibrant A from the top port of the reagent pack into a syringe
fitted with a blunt needle.
2. Inject sufficient Calibrant A into the lumen of the K+ and Li+ electrodes until fluid fills the
lumen.
3. Cover both ends of the lumen (both sides of the K+ and Li+ electrodes) with tape to hold
the Calibrant A in place.
Reagent Pack
1. Remove the Reagent pack from the analyzer and discard it.
Analyzer Tubing
1. Remove all the fluidic tubing and thoroughly rinse with DI water.
Analyzer Re-activation
If necessary, soak the reference electrode in warm water until the lumen of the electrode
has been cleared of salt build-up.
Calibrate analyzer.
1. Install the reagent pack and connect it to the ISE module. If the reagent pack is already in
place, shake it gently.
2. Pour the cleaning solution into the sample cup and place on the specified position of the
standard sample tray.
3. Go to the Maintenance screen from the main menu and click ISE ON button.
On clicking, the ISE Module pumps Calibrant A from the reagent pack and dispenses it into
the sample entry port to wash out the electrode flow path. Repeat the procedure if required.
XL-180
ISE Measurement (Optional) 12-10
On clicking, the ISE Module pumps Calibrant B from the reagent pack and dispenses it into
the sample entry port to wash out the electrode flow path. Repeat the procedure if required.
On clicking, the ISE Module pumps Calibrant A from the reagent pack and dispenses it into
the sample entry port to wash out the electrode flow path. Repeat the procedure if required.
7. After completion of purge cycles, select CLEAN, and then click START. On clicking, the
analyzer dispenses cleaning solution and Calibrant A in the sample entry port during the
cleaning process.
8. After cleaning cycle is over, perform 6 to 8 PURGE A cycles. Now the system is ready for
calibration.
This command is used to calibrate the electrodes of the ISE Module. The ISE Module then
cycles Calibrant B and Calibrant A solutions in front of the electrodes and measures the
millivolt output of the electrodes for each of the respective solutions.
These millivolt readings are then used to set up a relationship between sample concentration
and electrode millivolt output. The change in millivolts per change in concentration is the
slope of the electrode. The slope of the electrodes is reported in mv/dec (millivolts per
decade change in concentration), and should be within the following limits:
K+ 52-64 mV/dec
After the calibration process is completed, electrode calibration slopes are displayed on the
right side of screen. If any error occurs during the calibration process, the error code is also
displayed in the error message grid. If the slopes are within range then a box with green
color is displayed. If slopes are out of range then a box with coral (deep pink) color is
displayed. The previous calibration details with date and time along with the slope values can
be viewed. To view them select CALIBRATION, and then click SHOW REPORT.
If the electrode calibration slopes are in the acceptable range, the electrolyte measurement
system is ready for the sample analysis.
For Serum samples 70 µl and for Urine 140 µl (10 times diluted with urine diluent) of sample
is required for the electrolyte measurement.The slope is defined as:
XL-180
12-11 ISE Measurement (Optional)
10.To perform pump calibration, select PUMP CALIBRATION and click on START.
Once the process is completed successfully, values for all the 3 pumps CAL A, CAL B and
Waste are displayed. If the values are between proper range, then calibration is displayed
OK with green colored box else it is displayed NOK with red colored box.
11.To perform bubble calibration, select the option BUBBLE CALIBRATION and click on START
button. Calibrant A solution is dispensed in the sample port. Bubble calibration allows the
module to reestablish a baseline for detecting air-liquid interface. It can be used as a
diagnostic tool to see if the bubble detector is functioning properly. If the process is
successful without any error it s displayed OK with green colored box else it is displayed NOK
with red colored box.
The only daily maintenance required is to run the Cleaning Solution after the last sample of the day.
All other parts and expendables are replacement items (see schedule below).
12.10 Troubleshooting
XL-180
ISE Measurement (Optional) 12-12
XL-180
12-13 ISE Measurement (Optional)
bubbles.
Air in Sample 1. Cal B and Cal A are segmented with a) Electrodes are not properly seated
and Cal A air or compressed. Check compression
plate, spring and seal. Remove and
reassemble electrodes.
2. Fibrin or salt is plugging the electrode a) Use Cleaning procedure for module.
flow path. b) Remove electrode and clean or
replace electrode with plugged flow
path. Reinstall electrodes and
recalibrate.
3. Bubble detector is malfunctioning Replace bubble detector.
4. Waste pump is malfunctioning Replace Waste Pump.
5. Dirty sample cup Clean with cotton swab and DI water.
Air in Cal B 1. Cal B and Cal A are segmented with a) Electrodes are properly seated.
and Air in Cal air Check compression plate, spring and
A seal.
b) Ensure that all electrodes and o-
rings are properly installed.
c) Ensure tubing between reagent pack
and sample entry port is connected
properly.
d) Replace tubing between reagent
pack and sample entry port.
e) Reagent low or out.
f) Use Cleaning procedure for module.
2. Fibrin or salt is plugging the electrode a) Use Cleaning procedure for module.
flow path. b) Remove electrodes and clean or
replace electrode with plugged flow
path. Reinstall electrodes and
recalibrate.
XL-180
ISE Measurement (Optional) 12-14
2. Click on ISE ON button in the Maintenance screen. The software will detect the new pack
and perform priming (Prime A and Prime B) operation automatically till ISE module sends
OK status (air removed), maximum up to 10 times.
During this operation, the following error message may be displayed on the
error grid:
3. This will help the user in detection of bended or closed tubing. In this case, correct the closed
or bent tubings and again perform the Prime A and Prime B commands manually through
the ISE Maintenance Commands.
4. Once the auto priming operation performed correctly, the lot number and expiry date of the
new reagent pack will be displayed on the Lot No. and Expiry Date along with the following
information
Lot Number
Expiry Date
Distributor code (This information is stored in the reagent pack’s dallas chip and not
visible to user)
The above information can also be checked through ISE Pack button available on the Status
Monitor screen. Perform calibration with the new reagent pack and check the values.
XL-180
12-15 ISE Measurement (Optional)
Volume)
ISE IT ISE Pack - Time Out Dallas chip 1. Check ISE module
Occurred absent connection
2. Ensure reagent
connector properly
connected on Dallas chip
XL-180
ISE Measurement (Optional) 12-16
3. Motor
problem
XL-180
Contact Us
We welcome your feedback about the product. You can reach us at the following;
Address: Erba Diagnostics Mannheim Gmbh, Mallaustrasse 69 - 73, 68219 Mannheim, Germany
Phone: 49-621-8799770
Fax: 49-621-8799688
Website: www.erbamannheim.com
Email: sales@erbamannheim.com