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Sleep: Cardinal Center Moves To Tinley Park
Sleep: Cardinal Center Moves To Tinley Park
Study Design
Random, population-based sample of adults who were recruited from several Wisconsin state agencies.
Study Group
1,522 adults between the ages of 30 and 60 years
Sleep Assessment
One night of in-lab, 18-channel polysomnography conducted at the University of Wisconsin General
Clinical Research Center
Primary Measurement
Sleep apnea or "sleep-disordered breathing," measured by the apnea-hypopnea index (AHI) – per hour
of sleep, the average number of apneas (breathing pauses of 10 seconds or more) and hypopneas
(breathing reductions with a decrease in blood oxygen saturation of four percent or more).
Severe (AHI 30 or more), Moderate (AHI 15 to 29), Mild (AHI 5 to 14), No sleep apnea (AHI less than 5)
Mortality Follow-Up
Eighteen years, reviewing state and national death records up to March 1, 2008.
Mean follow-up: 13.8 years. Total observation: 20,963 person-years
Deaths
Total: 80 of 1,522 individuals (5.3%). Severe sleep apnea: 12 of 63 (19%).
Moderate: 6 of 82 (7.3%). Mild: 16 of 220 (7.3%). No sleep apnea: 46 of 1,157 (4%).
All-Cause Mortality Hazard Ratios
Severe sleep apnea: 3.2. Moderate sleep apnea: 1.3. Mild sleep apnea: 1.5.
Adjusted for age, sex and body mass index. Hazard ratios were significantly increased with SDB sever-
ity. Adjusted hazard ratios remained high after further adjustments for smoking, alcohol use, general
health status, educational status, neck girth, waist:hip ratio, sleep duration and total cholesterol.
Effect of Continuous Positive Airway Pressure (CPAP) Therapy For more information on this article
When 126 participants who reported regular CPAP use were please contact Community Relations
removed from the statistical analysis, the adjusted hazard ratio for at info@cardinalsleep.com or
all-cause mortality related to severe sleep apnea jumped from 3.2 (815) 773-9090 ext. 300.
to 4.3. The adjusted hazard ratio for cardiovascular mortality related
to severe sleep apnea soared from 2.9 to 5.2. These results In no way are the suggestions in this
suggest that CPAP was protective particularly against newsletter to be taken as medical advice,
please seek proper medical attention
cardiovascular death.
from a medical professional.
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