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Lecture 1
Lecture 1
Lecture 1
It can be grouped into the Red blood cell indices and the
Platelet indices
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INTRODUCTION
Red blood indices remain the most popular among the
haematological indices
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PLATELET INDICES
Platelet indices are potentially useful markers for the early
diagnosis of thromboembolic diseases
Plateletcrit (PCT)
Platelet distribution width (PDW)
Mean platelet volume (MPV)
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PLATELETCRIT (PCT)
Plateletcrit is an effective screening tool for detecting
platelet quantitative abnormalities
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PLATELETCRIT (PCT)
PCT is also called platelet mass and is the volume
occupied by platelets in the blood as a percentage
PCT = (PLT × MPV)
10,000
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MEAN PLATELET VOLUME (MPV)
MPV is the average size of platelets found in blood and is
typically included in blood tests as part of the FBC
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MEAN PLATELET VOLUME (MPV)
When total platelet count is low and MPV values are high,
it suggest that bone marrow is rapidly producing platelets
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MEAN PLATELET VOLUME (MPV)
A Low MPV means platelets are smaller than the
average
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RBC INDICES
They are used to help diagnose and classify anaemia
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RBC INDICES
The indices include:
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RBC INDICES
The indices suggest how the RBCs appear
microscopically and provide significant information
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MEAN CELL VOLUME
MCV (fl) = Hct (l/l) X 10
RBC (1012/l)
Normocytic : 80-100 fl
Microcytic < 80 fl
Macrocytic >100 fl
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MEAN CELL HAEMOGLOBIN
It is the measurement of the average weight (in picogram) of
haemoglobin in individual erythrocytes. It is calculated by
Alcholism
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MEAN CELL HAEMOGLOBIN
CONCENTRATION
It is the average concentration of haemoglobin in a
deciliter of erythrocytes expressed in g/dl
It is the ratio of haemoglobin mass to volume in which it
is contained
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RULE OF THREE
One should interprets accuracy of RBC count,
haematocrit and haemoglobin value using the quick
formula called the RULE OF THREE
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ASSIGNMENT
The packed cell volume (PCV) is also referred to as
Haematocrit (HCT). However, they are not necessarily the
same.
Briefly explain the difference between PCV and HCT
(your answer should not be more than one(1) page)
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THANK YOU
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