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Evolution of CES Chapter 19 Bioelectromagnetic and Subtle Energy Medicine
Evolution of CES Chapter 19 Bioelectromagnetic and Subtle Energy Medicine
サETIC
ANDSUBTLE
ENERGYMEDICINE
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1
9 TheE
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CONTENTS
NaluralEl cc t
rici
ty:ThcD iscovcryo faP eculiarP r np!r
ltyo fFish...
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TheMoue r
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CESComest oAmeri ca....
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.1
91
E山 IyE lccl roenじeph alo
gr aphyRc ぉcarchandt heSub叫 quentExp a
ns i
oni n
t othcT reat m
ento fMoodDi sor der s. .. ... ...
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..
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.191
Mechanisms0 1Aじ1
' 10n...
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92 、 今
1
89
1
90 B
ioel
ect
rom
agn
eti
candSu
btleEnergyMedicine
wasthen 叫 t
r odescribem
igraine.whic
:hi
. sderi
vcdfromt h
e tr
an信じれ111旧 Il
yt hr
o u
ghel ectro dcs.Thcb rainfu ncti
o nse lectro-
Greckwordhemikrania(ha
lft h
eh ea
d).A
fterinv
eメtl
galmg chemicall yandi tc anr eadi
l yb emodulatedbyel ec
t r
icali nteI
th
ea nci
enttrca
tmen
to fheadachewithtorp
edofih,Gal
s e
n vent
ion.U n likcp cri
ph eralc le c
tr omedi cine,CESh asb eenl ess
、
.vr
otc frequ
entl yc i
t edinolder.h i
s toriclit er
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ure.Kruegeri sp crh ap討
then rs
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tl he
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Imcmals clιapplicationo felc ctricc ur
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olapsus削 l Iwhena ppl
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ter.7A ld
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ld is
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ss pine.H issen sationsa ft
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Thcmo stp ow erfuls ou配 eo felectric
itycamcfromt he 50-vol
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hugeSout hAmcriconc c
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19ues ;1f cl
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sho ck ぉ0 1u
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r ted
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oa nalgesi a,thes eJ in
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ica ntin tcr
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THEMODERNERA
electrodct ol heforchcadandapo s il
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ee leclrodetot h ehand
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alt ishe ve nll
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-
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ba
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Atth ctumo fthel a
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y
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er ousp a
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tions,a longw itht hcp utali vcme じh a
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explain叫 I chphenomena
乱ppcar、 気o l
TIctimesam il ddiz zi n ~日 oc curs , a
ndad ru、
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cd cgrec1)
1
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ctrici
lyh 出 his t
or
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ti cally physio
l(lgi c
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si naぃ山 n陀 l axt
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so fl hehndy ,c ra
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日 pys '
ti
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on.uS Lla l
lyo nh i討 s itlc
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ationbecome d
沿 ccpc'l
orCES.i sa行p e
citict ermdenot inge1e ctrica
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l : th
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alh cals
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icesthatd eliverc l
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TheEvol
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ani
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tro
the
rap
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imu
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ion 1
91
l
ni t
scOJ 1tempor
ar yform,CESi sade sccndal
lLn tL
" he 【04000h ertz( Hz )andcur renti ntensit
yup1 08mi lli amper es
aforeme
nt旧 ned i nvesti
gations
. l n t he clectr
oconvulsi
ve (mA),wh ilemor er ec
e nld evic e
su til
iz ef requenciesa sl ow
ぉhockparadigm,1 20v ol
tsal60Hzand500mAwasa pp
licd as0 .
5Hzandc urrentl、
it ensilya slowa s1 00m icroa、np erc s
in 0.
2sbu rsts
. From t h
ise l
ectroan出 thc
ぉia was dcri
ved. (μAJ円 0' 1c our叫 a llI he措 v ariahl出Ille al
】l tha
tt her e sults
whichu scdar educedc ur
rc n
tl ev
clo f2v olt
sa t700Hzand from diffcmmCESd cvicesv a ri
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30mAg ivcnf orthedurati 1o
ol fJn,o
り rsurg
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llya vailablct oday
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leepw出 p r
oduc edb y700Hza t1v ol
tand Thee vollli
1 ono fe lectrodep lac emcJ1sw
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ular ly
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ic凶 t ypica
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ngefrom notable
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l heU .S.f r omEurope,
0.
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to r1
.5v oltAAo rAAAba llc
ry devicesメu cha st hcE Icctroぉo neuぉeds alineぉa turatedga uzc
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esp l
ac edo vere achc 10sed
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n cedo vert he1 1剖 l
1 oids.At
thet imei twast h oug
h tt hatt heeyωweret h
eb e
st,i fn ot
CESCOMESTOAMERICA
theonl y
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tenedbycli
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ata ppe
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be gant op lacet hef rontale lectrodesj l
ls la bovee ache y c-
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1 "
、 inSl
ant browwhi l
et hcr carelectrUllcsr cmaillcdo verthema叫 o i d気
s
leep"achievcdI hroughte.
chno-wizardryprompt edin depelト Suhs eq
llcntly,thef r
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d
cntc on
su l
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dp ro cessesjustbeh in d
k
etadcvi ceh en amcdt heElcctroぉone50,a sAmcr ica'sifl叫 ca c
hc ar.s ot hatt h
cc urrcntwcntl a
tcralya crosst hehcad
p
ortah
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edc ranioelect
ricalsleepg ene r
ator inslcadofa nterio r-po日criorly.Thi sc ausedv e
rtigo:the refore,
aro
uml1 973.17 Pri
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ce'sd ebut‘lwanovskyp llb
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it clcctrodcp la ccm cntu同 dl ouaycmpl oysc nrc lipc leclrod cs
o
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Accord ingt op rom o
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e r
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n ta crosst het cmples.15
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1
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Iv eryweak,p uls
ating
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ctricalc urr~nt produc e
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sinstrumcnt EARLYELECTROENCEPHALOGRAPHYRESEARCH
passe
st hro ught hep a t
ient'
sb r
ainbymc.::ans0'1foure1ec ANDTHESUBSEQUENTEXPANSIONINTO
lro
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出 woa rcp lacedonl hec10seueyclid
sandi ntheb ack01
THETREATMENTOFM O O DDISORDERS
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eekandcompactE lcc
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logic
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lizc
dinI hcUSA,p sychoph出 ma cventst hato ccu rrcd wh c nc urrcntwasa ppli
eda crosst hc
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Studieswer ec o
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Diastim,E lectrodorn,E lectr
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lo ft h
ep alic n
ts.Mostp atientsa lsoshowcdi ncreased
others円 quulityandq uantityo ftheEEGa lphar hythmwit hi ncreas
ed
Thec 1inic
alintentwast h
ate l
ectro
sle e
pt reatments hould am plitudeint hco ccipita
l- par i
e tallcads.21
induccs lccpi mmediatelywhenl hec urrcntwasappl i e
dt o Wci日 c ondllc t
edane arlyEEGs ludyi nas l
ecpl abora
thep川 I e
nt'shead,andt h a
tt hepati
ents hou ldremaina slecp tory,inwh ichp aticnlswhoha dbeend i agnosedw ithinsom-
natur
ally.onceI hcs l
eepwasi n
duced.Thald idnoto c
c ur, niawcrca llow edt oslecpi nt h
c i
ru su alwayi 1lheu ni
v c
rsity
however ,eVClt houg hmanyoft hecarliestd inica
ls t u
dics labora t
orywh ileh av i
ngt h e
irEEGm onitor ed
.F ivepa ti
ents
inthcUSAf ocuscdond iscov
eringthewave 'ormt
l ha
twould wereg ivens l
lbs enぉorye lectr oslecpt reat m
e nt
s30mind aiJy
successfulyi nduces leepYR es
earchersu sedav a
riel
yo ff r
e- for1 0d a
ys.andt ivewcreg ivenshaml reatmcnts.S ub
sc quent
qUCll
CIC 人c ur
rcntlevcI人 andwaveform ぉaswcl凶 c lectrodc mo nitoringo ft heirEEG討 Jcc pr 叫t ern見 showedt hatpa t
ients
configurat
ions. Unf or
tun a
tely,notallr e
p receiv i
nga ctualt reatmcnt、 .
v e
n t10s le
e pf asle
r,メ p
entr no
l 志
ti mei ns la
gclVs leepd urin gt hcn ight,hadf ew e
rn o
ctur
naJa 削 kening s,wenthac kt os leeps oonc rwhcnt heyd id
1
92 日i
oel
ect
rom
agn
eticandS
ubt
leEne
rgyMedicine
、IJ山.;r
ala hcommented0 1
1ps ych ial
ry'sf uture.p r edi cting forb
山 b jec
e
t a-endo
thada21
rphilJ was 50% from ba;
9lkI ncr ease. J
5Thc 日 d
予
at
el
.s
int
h
!a
ou l
lt
hou
dbevi
ghont
ewed
!
de ct rica ls l im u lm iona Hc ctedt hcq uan tity01 'q ua lityofne ll- showedt ha
tCESr cac hcda l
1c ortic alandS 1b
l cOfli cala r
c as
rotran~‘mitter r ele ase日 Neul'Ot ransm i
t tersa res torc
tli nv 臥ト oft hcb rain.p roducingc h ange討 s imila rt ot hos ei nt luc
edby
cleλP‘ Ic klS,,1
e ι hcm i calst hatu pons timu lali ona rer el ea sed anxiolyt i
cm ed ic
a tions羽 .6 Man ys ymptomss ee ni np s
y chi-
inl Os yn a p
ti cs pa ce1 0e xcn ana ctio n.S igi smund' 討さ r ou p atricc o n
dition人 s Ic
l h辻s mx , lety,1I1SOml1lユ. anda t
lc nLIon
f o un dt hatel ect r
i じa l叫 i l
111l
l ation0 1t
' hcb ra int cndedt of Olじe detkitd i
sordersa ret hough tl obee xace rb川e db ye x cessC OI
t hep rl!ぉy
- na pli cv e sic
le只 p reSCl1t(Q r ekasct heI1 じo n tcl刊誌 t
i calact iv
alion,4
7AsAnfMRIs t udyi na na nxi 目 yp op ulation
inlOt he showedt hatCESc al1sc討じ o rticalb rainu e activa t
i oni nt he
mi dlinef rontalandp arietalr eg iols0 '1theb rail】 af t
erjllS t
on c20mintreatmen t.~~ An othc rfMRIs tudywasc onduc t
ed
asp arto f"randomlycon tr o
llcdd oub lc-blindl rial( RCT)
inap ai npopulationt hatr evcale dg r e
a terd ecr ease si na ver-
a gepai nl evds(p=0 . 023)t h ant hos elIS】ngashamd eviじem
re C
CIV11lgu おualc arew ith outCES.4 り Thca ctiveCESd e v
i じe
D
eJt
a(1
.0-3
.
5Hz
) A
lph
a18
.0-1
2.
0Hz
) B
eta(
12.
5-2
5.0H
z)
.~、
• •• ,
0
.00 0
.03 0.
06 0
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.06 。 0
.03 0
.06 0
.00 0
.03 0
.0
6
B
eta1(
12.
0-1
5.
0Hz
) B
eta2(
15.
0-1
7.5H
z) B
eta3(
18
.0-2
5.0H
z)
。 。 。
。。
.。
.
0
.00 0
.03 0
.06 。
。 0
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.0
0 0
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3 0
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0 0
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.0
6
mc じhanisl
1lsk nowl t obec onsistcmw i
tl 】 thef u nctionso f rel
atedc ompl山 n tsandd is order
s.CESma yh el
p1 0p rcv
ent.
varIousphy siolog icalf unctio日sundt hee f feCLぉ 0'
1d rugst h川 lesscn
.o rale viateI hesei nane xt
remcl y泊 fe出 ldv eryco蕊l
AI
pha
-S
tim¥lA
IDw
ave
for
m 3000p at i
ents凶 却 [n川 o thersurveyo f152S erviceMembers
300
undv eleranscon duct
e dforFDAi n201 Jt heoutcomes.wh il
e
三2∞ t川 町 gn
s it
icam,、、r
札 cn olquileasr obusta sp r
iorsurvcys0'1
刷
v ci
vilians.幻 However ,at hir
ds U'v
I e
yc on ductedin2013 o f
邑1
00 2861S er vic
eMembers.v eteran
s,andc i
vilianswasc10scr10
E
。 theorigi na
ls urvcyo rcivili
al刊 T hisconl innsthco bsc
rva-
』
出 tio
nt hatS erviceMembersandv cteran
swhou seCESmost
E
S-1
00 li
kelys uffe
r from more e .
xtrcm et rauma, and.t her
efo陀,
H
E cxpenencc討l i
ghtly]essc fli
cacyt hanac ivil
ian-onl
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5-
200 Never
t heless.ther e
sl
tlts問n1aJn日邑 n incant(, 50%)a
;
0 ndthey
u
.
tF
∞
shouldb econsidcredasc l
in
icallyr el
evan igurc19.3p r
o 叩
2 3 4 5 6 7 8 9 1
0
vi
clcsad cta1
ied日 lmmaryo fallt hrcco ft hcpOSImarket -
T
ime
(s) ingsu rveysc o
n ductedforFDAt ota
lingne ar
ly6000S er
vice
Members, v
eteran,andc ivil
ianse l
f.re
porl当
FIGURE 1
9.2 ThcA
lph
a-S
tim w
avc
for
msh
owno
vcra 1
0s
p口io
d
仁H
MODERNRESEAR
AsCESh a
sbecnc e肝 edb
l ytheFDAf o
rl helr
catmentof
wascon sisl cn
tw itht hes t:lndar dso ft hed a y.b l
ltf a
llwc1 l
bcl 、
ovmo dc rnst a
nd ards.Dcpcndi ngont hed e v l ce.thcq u al・
a
m
n
a
X
r
Jc
.
il
t,lnsOmnta‘ andd
y
yforthesci ndica
ti
c
p
o
r
n
s
c回 l0nS
.Aぉ ar
l
ll
e
s
じc1
llJ
78,i
9
r,ther
li
su
ear
s
cdp rト
enumer-
it
yo ft hcr es
(ふ1C
1
" l
1p rotoco l,i nclu dingt hcb 1
in d ingmethod,
ouss u
pport
ives t
ud iesandpubliじat
iol
lSb u
to nlyrc
ccntone見
int hos ee arlys tudiese xhib itcdI11 ix~ù 問slllts. ! ~ Whilet h erc
th
atcomplyw itht hemorer i
gidcurr c
nls ta
ndar
usw il
lbc
arcc op icso fthcNcu roton ewa 、
.
reforms oldu n d crt hcb ran d
describe
dinthis日 C 1
10
11.
namcso fCES U llraandH ea lthP ax,s cvcralo lh
crp riv atc
Jabe le
uv e日i on
so ft heset h ata rcs t
illont hemarke t山 宮 p ro
dl1ccdh y只m allcomp anicsw ith1 10r esearchs t udic
s1 0山 l ト
ANXIETYDISORDERS
portt he i
rじl aims
Mo 叫 r c ccn
tCESs tudie su sc山 l ia
hlcandv alido ut
,(O J
llじ Anxi etyd isor dersar~ cha r
a ct 即 日 以1byami じi pat
i onofaf u tu
re
I
11ca sur emc nts c
all沿 T
! het n.日orityo ft h
e s
eh av cbccnC OJ1- thr
ea t,c xce州 i vcf ca
r,andr cla
tcdh eha vior ald istu rban ces
du cledw it ht heAlpha-SlimCESd evice,whichh川 b ecn Fcari s削 討 ociat euwit ht he山 町 お r espons c,o r日 lrgc討 ofsym.
pr o
grcs siv clyr c
f i
nedo vcrt hep a s
tt hreed cc a d es.Itl l
SC日 a pathetica rou salS CCI1inngh lo rO ight問 符 p ons es‘t hou ghts
comp lexi lndp atcntcdb ip olar出 ymmetricwavcf ormc on - ofimmcd iarcd ang er,andc s capeh ehaviors .Anx icty日 a l
so
si
s '
li
ngo Fm ultiplef re ql
le nciesa ta5 0cad l lt y ιycleh aving oncna ssoじi ateJ¥-¥' hi
叶 ncre as edmus dct c
n sionIln
. uv igi l an
ce
av aria ラJ
l cp uls
ew id thwi thamaximumd ur ati ollo f0.5Hz inpr eparationf orf utur
ed a ηg eralon gw ithc au
ti 1s
ol ora v oid
(2ゆ p rovi dedo vcra1 0st imef r am ew it
hr and oll
lf actorst o antb eha
v io
r s.A n xietyp a ticntst ypical l
yo vere s
ti matet he
av o
i dh abit uati
onbyt hen er vouss ystcm.ThemaxImumcu r - dang crins Itu atIonst hcyfe aro ravoid.A n xic tyIsabou tt,、Vl
ce
rcntl evelo fthcd cvicci s600microampereぉ Thcimpe d an cc asp revalcnti 、
nνome nロ
ra nιew it hinwh icht hewavcformp ar山n etersr cmaInv alidi s Thck eyf eatureso fgC l1c nda nxietyd isordero rGADa re
fro1
111 00Q t o1 0KQ.Thcwavcformi sb ala nc ed10a chic vc pcrぉistcntande xccssivci l nxiet
yundw o rry.whichi mp airs
ol1etcurrentincitherdircctionasshownioFigure19.2 worko rs cho olp erform an cct h川 t hei ndividua lf indsd if
-
Randomly c o n
tro lledd ouble- blindt rials0 1 CES c
' a n tic
ultt oc ont roLI na ddition,a ffectedp alicntメ e xpcnence
bca じC O!II
T ヲlish
cdt o dayi l
lt hcぉamem‘iOl1C rl 1s cd10c v alu一 phys icalsymptoms,i ncludingr cslc州 n e州 o rf e e
l i
n gkcycd
川ep ha rmac eUlicals.Asd o sag ecanbep ortr a y edasc urr ent Upo roned 呂e ,b einge asil
yf atigued.d i
H h.:ul
Lycon cent ra ti
ng
inuirect l
yp ro
portiona lt ot ime,d ouhle -h
l ind in gi s以 ;hie ved ormindg oin gb l ank,irritability,1lU
1 気じlet ensi
o n.a nds le
ep
hyr edl1c川 gt h
ec urr c1lt
1 oas ubs ensory1 00m icroamp crc s distur banccs史
whl iei 即 日 制l n日 theu ぉual20mint reatme1 1lt imcl oaf u1l An xietyd isord erぉuffect40m illionAmericuna d ult
sa ged
ho ur.Thef ollowingi sasummaryo ft hiぉl110d ernl e
velo f 18a ndo ldcr,o rab out1 8
.1 %o ft hepopuJ alion
.A nxi ctyd is
RCT山 l d
ie s.opcnc linicalt r
ials,a nds ci
cntiiica l lyc o n
d uct ed ordersf r eq
u entl yC O-Qじc u
rw ithd cprcssi v!d
l
. isor d
e rso rs ub-
sur vey日 叫a nc ea bl
1scandmos tp eo plcwhoa red iagnose t
lwi thone
typeo fanxi etyd i sordcrof tend evelopo t hcr sY
Ta blc1 9
.1l itぉ n
s inerandomi泊三dcOl lt
roJledt rias(RCT),
l
SUMMARYOFTHREESURVEYS(
N=5917)
cighto fwhicha red ouble- blindHIH .01
l lCt hati品 川v estlg ato
r-
P
eer-re
vicw
edoutcomescondu
ctedOntheAlpha-
Stimbrand blindw it hs 1m
l mari出 o ft her csearchOlltcome 市b asc d011t hc
o
fCESf orFDAfrom2500p at
icn
lsurv
cysp u
bli
shcdin2001 measurements c 川e su scd.T ablc1 9.2showsf ouroJlc n- lab
cl
c
orre
late
dwellwith47p hy
sic
ian
s'repor
tぉo n500pal
icl
lts studiesandf ouru問 rs urv cys1I1V出 tiga tingt hee f
f i
c a
c y01
T
hi長 da
tareve
aledthata日 gn
ifl
can
teffcctofatle
ast25% t
r e
ati nga nxi etyw ithCES.T able1 9.3以lmmanze ぉt he且nd -
tm
provem
clltwaぉ r
cport
cdbyn i
ncout0'1tc
ninagroupo f ingso ftwom C la-a nal
y ぉeso fCESs tud ieso fa n
x i
c l
y .The
9&
1 Bi
oelect
romagnet
icandSubll
e EnergyMedici
ne
S
elfr
epo
rtso
fimprov
ementfromAlpha-5tImu
ser
s
compar
ing20
01.20
11.and2013s u刊 e
ys
S
igni向c
ant注
( 25%)
。% 20% 40
% 60
% 80
% 100怖 I
mprovement
2日01C 25.
79も 6
7.0% 1 92., N=679
7%
Ao剖 et
y 2
0115MV 2
0.2% 46.6% 66.
7, N=11
% 4
20135MVI亡 23.4% 59
.5% 82.
9崎, N=714
2001C 28.8% 6
5.明色 93.8%,N=163
Insomni
a 20115MV
20135MV/仁
20
.
20
4
.
4
%
%
4
4.8
%
57.
5拍 .
- 65
77
.2%,N=88
‘6%,N=230
200
1C 21併も
36
.0拍
o
'l
も 3 54
9%,N=31
87.
.0%,N=89
8
Depr
ess
ion 20115MV 1
8.0
9も
201l5MV/C 20.
0'
lも 5
9.7目 79.
79" N=4
令 66
200
1仁 3
2.0'
lも 6
1.1抽 93.0% ,
N=1,
949
P
ain 20115MV 1
5.1% 30明る 45.
1帖I ,
N:73
201l5MV/C 2
3.2怖 57.
7
'る 80.9, N=730
軸
He
adache 20115MV 1
8.5% 前ゐ 58.
5, N=70
%
201
15MV 2
3.9% 38.6% 62.
5, N=88
%
PT5D 20135MV 26.0怖 63.
7拍 3 89.
7, N=146
%
TotaIN=S,
917
ロImproved25-49明 白Improv
ed2
:50%
C=C i
vi
1ian
SMV=ServiceMembersandVet
erans
5MV/C=5e刊に eMembers,Ve
担r asandC
n iv
ili
ans
F
lGURE19.
3 S山 lTn:lr
yoft
hret:山 r
vey fcr
ani
ale
lect。
泊
rotherapystimul
ati
unu
ser討 (
0=5
917
)
TABLE19.
1
仁ranialEl mulation(
ectrotherapySti 仁 ES)RandomizedControlledStudy(RCT)Anxi
etyStudies
P
rincipal
I
nvestig
ator T
olaln Su
bjec
ts 5tud
yTy
pe M四 s
urementSca
les
/Oul
come
s
sarday 11
5 An且 i
elvP
ali
cl
l!s RCT
.DB Hami l
tonAnx i
ctyR; u
in gSc al c(HAM-A):l nt hcact
ivl
!tr!a
l tmcnfgru l1 p、 R .\ Ç~ h~u a
Cla.q
l Jc crc出co r;
?:
5(
),,i
k
1 ns corcsf rornh ast
:l
. in
ctl)cnJpoi
ntonI hcHAMι A(p<O1 .川1).
Thcrcwa sa羽目l il
icantu ifre r,巴nじ巴 b~lw~en groups(p<0. 001.l=(
t )り
- 1 -)f r o m
has ei
1nctocnJ[lointu f叫 UU)ιT hc1¥
),コmd
( ccrc出じ いnt h
cHAM- Ai nt h ct n ::a unenl
grnltpof32 .
H':
.
r(1 9.1
:1
9t u1 3..' ¥7)山I Smn 回 t h
ant h
rel
!(月)t im
cst heme andC erea!
-
.c
り 1l1
1cHAM- Af o rthc" h川 1 g rul
1p¥)1'
り.1f
1t
.(21.98to19.9削 frollh
1 a:. c
1ine1 0
cnupoi n
roft hc刈 utly
.
Lc
c‘叫 o
可 Pr
じop
cra
tiv
eP江
Ilc
nt百 RCT L
ike
ltAnxi
etyS t
ak:CESgro
uph、l
.sig nilie~ntly l
l o¥Vc
rS(
'o
・ resf romhas
cli
ncnn
しikcr
lanxid
y,-:C
llk
.th
att
hcc
ont
rolgroup,whichg o
tl h
cl l.~ua l c
are(
jJ=0.01
6)
Thcr
ewa 且 砧l
sor
cJu
cti
oni
nwit
hdr
awals
cor
csf
orpmkntsuu
rin
gin
jed
ion
s
(
/1=OJJ4t
))
.
K
irnc
ta..
l. 60 Pr
Cl
I!X九百 l
iv
じ, Pa
ticn
Ls R(
T.旧 UkcnAnx
ictySC<
lk:
'CESgrn
uphadsi
gnii
lcam
lylo¥
¥'
crs;u
t r
cs"‘'
romh a
叫 l
in
con
L
ikcI
1an
xict
y:-
.
ca1cth
anc
onl
rolg
mllpatendpoi
nt0'
1swdy(1'<( )
.05.d=- [ U~S).
Strèntzsch ~7 )
H C
hro
nic
alyMcnta!
l lyI
I
I RC
T.、DB S
I、ie
lherg erS t
atcTnutAnxi
ctyTnv
enlo
ry(STAI :CESgr
) ouphads
ign
itk
:an
tly
Pa
ti
cnts lowcr出 仁 川 c
sfron
lh a
scl
inc005AI(in
Jic机 t
ingl
csss
t:
¥t
c:ln
xic
tyJth
an!'
hamgroup
.
l
telllJ
p ointnfMU uy(p=OJ 日.d=一り斗1).
Che
nct:
lL旬
. {
心 C
h il
J刊 nwithMixcJ RCT.1
s ZungAnxict
yS~~lc (
5 A5):T h~ ANQVA' !hnweJtha
to nSA5、t helUa i
nc ll
'el
t
.
^nxicl ln
Y< dDcpr
c同 i
vc hctwc
cnCESgmup祖 n ds ham comp:.i
fat
orgroupw出 s ign
ilic
ant( F=8 3.21
Dis
(l
J'Je
r( MAD) '<
1 0.01)Changc
咽 si
nEEG0 1O .
: c
ipi
ta
咽 lLnhcsviahrainelec
tricalaClivi
l)
'mappi n
g
(BEAM):o nl
c't:
1 mdrightα1r CVCl
i!
cdlhcma i
ncffcc¥orgro u
pwass i g
nilica
nt
(F=5.98.
]1<0 .
05;F=6 .3り.f
I<0 .0
5):Ol
llef
t~nd r
it
:h la2 thema incf可fcctof
gro
upW l
lSals
us i
gnii
lcant([0=7 54.JI<O. o
!:F=6 .72‘p<( ).
05).
Cor
kcla
.!
l 1 74 Fi
hfl
lmy
algi
aPa
tIcn
ts RCT.Ds Pn巾 k0' 1Mo odSta
lcs(POMS)f oranxic
ly:CESg rouphadsign
il
icanll
yll
lWCI
OL ~corcs fro
mh a.
.
cli
nc011POMSf i
ndil
'
atingt
essanxIct
y)thanshamg r
oupatend
j
lOilt
l01'stu
uy(1<O
( J)1
).Opcnl u
bclCE5g ro
tlphaJ:-.i
gn
il
ican
tl
yluwcrscor
cson
POMSa tposトt
c叫 f
r口mh a
:世 l
inc叫 or
c:
-
.(p<0 .
(旧1).
TheEvol
utionofCranialElectrotherapySt
imul
ati
on 197
TABlE19.
1 (continued)
lectrotherapy Stimulation(
CranialE 仁 ES)RandomizedControlledStudy(RCT)AnxietyStudies
P
rinci
pal
I
nvest
igat
or T
ota
ln Subje
cts SludyType MeasuremenlS日 l
es/
Oulcome
s
L
il'
ll
tb
rl
lU
O'
,
i' 。
() F
ihr
omy
alg
iaPa
tic
nb lH
RCT.L P
rofilc¥)
fMooJS tal出 入 n x
ictySuhs 山IcI POMS- AJ :CESg roUJ lh ad幻 g nitic
anlly
OL lowC
'rSCOl山 0 1
1POMS-A( in di山 川 区 lcs~ l In xi c ly )f f( ‘
)m haeJ il l ct han.~ha m gr
ollp
Tc
a ndpυ1111川 山 l dy( p=;; 0
. 02. d= ベ)印).T hc悶 Wぷ 1 11 ~igni Ji canl d
( iff
c印 n cc10
0作: 11Lah e1じr o州 刑' c
rgr 山 p' 1 romp r Clcslt op o s t- t e stonPOMS-A( 1
'>0 . 0
5)
、
,
yjnkk' リ n D
enl
alP
ali
enl
s RCT
.DB V
istla
lAn al o gS calc(VA針 。I n verseL ik crtS c a lc CESg
ふ 山 lIPl l
<1d i
ち gn
ilk:a nll
y
I
mv crscúrc~ fromh asd inc.i n JicatingI c
附 anxh ::ty .OnI hcVAS(p<0. 02,
d=-0 .(1)a n dhighe rs core話。 nL ik crtS c a l e.i n Jk a li ngl essanxktyI p<υ ()1)
t
ha nshumg r P‘
山 ' t
lcnu似) inl olぉt t
ldy
V
ori負 制 1
05 Pおう!
chi
at
ricPa
tIc
ntsw
ith RC
T.口B S
tatc^ nxi
c tyI nv
c ntory( S AJ
):CESgr ol1phaJ討i g n i l ka ntly[ o wc r叫 O 叫 ミ ( 川dicat
ing
Anxiel
y 1
<怜i l
nxI
elY )O l
lSA(I hant hes ha1l
l< 1
IlUc o n t ro [g r o u p 沿 a
tcndp o i ulnfぽ u Jy
(p=o 叫)() I. d~ ー l 副}). C[ Sg r
oupha J.~ i g: nili l';H1 l l y hig hcrl i n g c
rt ernp:印刷出
ど荷 刷出{Jl=0 α)1.f/=0 .5t
l).1I1d討i gnilit a
n t l yl u w c rEMG叫 o r引 ( 1'=0似川 l
d=-1 .0お).i n
diピ臼 l
ingl c蛸 a n xi cl
)
' .Ih:
.
1 1、 h: H nCE .f)a ndc u n
lrl lg代川 p ミ
1
B:i
nvc
:
-.
lig
ulol
'hli
nd:Ds:
Jou
blcb
lid:01
n .:opc
nla
ょ:
t
l
. 11=51
>5f
: ora
nxi
ctyRCi SwJics
TABLE19.2
CESOpenLabelandSurveyAnxietyStudies
P
rin
c i
pal
l
nvestig
ato
r T
ota
Jn S
uhj
ect
s StudyType MeasuremenlScales/Outcomcs
Pr Íl'c~ 1 1
46 Servi
'cMcmb
l
. !
¥l
'
、 S
ur¥
'cy 7-p¥lin
lL i k
c rt礼: alc.Ofthet ot
alg fl叩 63.rkr
l cpl1r1c Jf e
W ¥!f1寸 SDs ymplom 持 a
nddini c
al
andVet
era
n馬,¥
、 '
i
th 11] '0'
1
1 、 elllcnto f ;日0ψ(l 1n、
町
p : C11
1C11l{ )
fs uh stanl ia
ld i nicali111 ~xl rt anc l! cat
eg nry
.Dworkin
PTSD " 川 町 wh ilc2 6
. 01fl陀戸川叫 c lini,,"
a linljl
nlVCm 山 1 1 0 1I
' 可 S口叩lIl]lt Oll1S hcl wccn2円 < 1nd
49時(Im pro vcl l
l cnto f1l10ucm l
cd i nk ali mp ortan c c ).[ 1
1t hc1 0
t: I
1g rotl p .89. 71
h:叶
陀 ~ pom 1c nl s rc似 川c dき2 5 t
kf ewerJYrSD~y mp tom ぉ川 dd iniα\1 i m p rtl¥'C mCn lwi thI he
州日~or il y o fI hc~c rC~ 戸川 dcnt ミ "'P(市川 19 2: 50 切 impmVC IIlC11 1 i nPT SD
P
rI'e
l l
!
. 714 Ci'
¥i
lian
!九5
Memhc円 <
ピ円i
¥n
u
c
e Stlrv~y 7-似)
刊 l
il
p
1l
ro¥
L
'
iJ
c
.
.
m
crt討cal
c川 o
c
.0'
f250 ;
t
1I
を(
heI
imp
・
{talg
l山t
r
roUJ
cm心n
.5
l
lnfs
9.SIi
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:r
li
e
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l
u
ia
r te J1
lI,."
li
剖語 a
nica
n
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x.i !
Xl
l ya
rl
:
n
Jm :
ddi
cC:l
ni
l
e
c
g
a
l
ory
Vetera
nswiL
h Dw υ『 k川
比 in
,じ叫E泊川1 州).wh 、lie23ι
l
己 モr
℃ ピp
陀 ο
叫a
口1 e
dC叶
え汁i
[
;,
川'
"仁a li ,
川叫
En pr ov e c
引'"児 n10'
川 1
,
I
I1X1Ct
y a u"49 ~t ο"(川川
nn戸pm v C
引I
llC
引11
10叶f n
川B叫l
α 忙c問 t edi 川IKαal川河川 rtan~c). I nl hcl olulg rolp.H2
l , lJtk0'1
t
訓
山
川E
"
叫“
刈
叫 引、
町宅 旬 凶
目
"に
山叫
_
.
‘
仁辺
‘
r目 p ond ent 品 問p orted225係 kssa l1.x ic
t ,
山
y dじl in in ¥!l mp ro vcl11c 川 wi t hth巴 mj
‘
to rityof
thc scr c sp川 d cn tsr cport i
n g:?SO鴨 川 1 pro
、
刊 川町 "
日r
acl
'ia
nnω 2 V
ct¥!
ran
swi
th 01
. 口a i
l ySym刊の m Sci cril)
lR< lling:-.- Tre a
tn lCnlLog( ()-1 (
))d CCI山 町 dfmmab ascl inc
PTSD me: mu f61 0(l post-tcstmふ1Il0' 12(p<0 .05.d=[ . 6
1 ).PT SDSymptomS 仁川cI n lcr
view
(PSS- I)wI Sr cdu ccJr r om 34
- 10 [
:
1anJ29t o 10 川 t h cr e 叩 C'
: I W p au c nt只a nd
‘
日- e.
xpel 'i
e ncingde crc出 c df r um71 02an d1}t o2 . 八 、叩i da lKCJιreas edf rom 1 5t o7ιmd
ゆt n,5
,: ln dI nc氏、よ、cda 代、u 只alJc c r
C
i l.
'、cdf rom1 21 l>4 11 nd1 1( 0可
By~( ri l ~ ky f> 1 1
2 G
c nc
ralAnxie
ty OL Ha r
n ilt
ll lR atingS cu!cr orA nxi ety( HAM-A).F u u rDim e川 i on alA nx i e tya 1dD
! cpr 白羽o n
Disor
dcrPal
icn
ls Sca le(FDADS):A nxi c
t y,;c
l or山 d e c
r e山 cu~ig l1 jli む antly onHA M- Af rom ba~e Jî ne t
o
Cn d[lOi n lοfs tu d
y( p=0 .01,11=--1 .52 ).AnれClys c or c対 wcrcs i
g n i l
i cn nlyl o w
cr( 11
l主)ADSaJ山1 11p oinl0 1叫 I IJ
yr romh a岨Iill じ( p<0 . 0 39. d=- O. 7 5 )
Lue
lal
.M 32 ChilJ
renwilh OL Zung^nxiet ySca le( SAS ):Fromh a 、
)e l
inco f5!UO土 1 1.5010j>¥減 I -
IC叫 4 5.9 1土 1 0.36
Emntional (">0. 01);1 3ピ祖先Cぉ h ad則 gni f
icantcl .i
'dt4 1%) .1 7ca柑ぉ hJdcff
cct153~話), andthc
Disurucs erfetw‘ 悼 川 V
c ‘
li
ld川 【",1)l'a同ぉ {61i
f
-) :th
cl('
I¥n
lc ffccli
vera
te¥V山り4ち も_Ski ntemperatu
re
(Anxiιl
yl ' 叫 I
0 p<ll.Ol) 叩叫 u li
chl oodpr cおお ur
cdropped川 dI hcpulcl
s o
w ιJdownaf !crthe
‘
t r
CJtmcn.
t:1ndI hcJin'c1引にι swcr es igni
ficJ f
1
I(1'<0 .05).2
6c 剖 C只follo wcdtP(
l 81%)
(1fwhich24C <l世話 hJtllon g1山 t
ing dlicaι)
'wi lhftょli
evc
dorel i
mi na
t ed詩ymptom句、 and
2c ns山 had悶 l apscof討ymptomwhcrct l
ru.
g sv.'
cren ccdc
d1り 仁ont
rol thc
i r尽ymptoms
口
、ic
n:a
shl
'
‘ 1
97 A
nxietyDis
nrJ
er OL (ト](附 N u
meric;1 1R ati
ngS c alc(NRS ):SutJjec
l沿f:1lingofanxic
lyW3 Ss ig
n i
il.
cant
lyl e
ss
P‘t
Ii
cnlぉ f rom1川 崎linct I
J1削 I-L t(p<(
cs ).05).S uhj
e c¥
ピp hy si
nlo
gica
lmca .
"u
r 出 υ fanxicty-
EMG、EDRa nt
lTC1llト-changcds ignitic
antlyfmmb ase
lin
c1 lo
0! st-testindi
catingIc
ss
a n
xicly(p<0 .0 5)
{
('(
llI l
inu
ed)
198 Bi
oel
ect
romagne
ticandSubtleEnergyMedi
cine
TABLE19.2 (continued)
CESOpenlabelandSurveyAnxietyStudies
P
rinc
ipal
I
nvest
iga
tor T
o 11
l< n S
ubj
ecl
s S
tud
yType M旧 suremenlScal
es/Ol
l
t印 mes
K
irM.
:h 202 ScrvI(
'!
¥MC 1 11bt!四 Sur
吋 y 7
- po
inlL ikert~ a k : An' ¥i
cty( 1=1 1.
.1).Of th巳 t otalg rou[l.4 6弓 安 問 戸 川 e dleおお a n x ie ly and
clal叫 jm
; JVch.:m l1~ ¥¥11
th dinic礼,imp 仰向Illc IIIOf注50 1
ffwhi k:: W.2 ;
rfJ 'c pO 1c
r Jd in iじ,1川 l p rov
cmc ntl l
fa n xicl)'
an x;
ctyl in du d出 hetwe en25 (,毛山叫~l)~争 ln 1 heI ma!g roup.6 fi .7をi
'刊 誌p o.叫 e nt
sr じp o口od之2 5%
pηTS口 川
口mp即 vcm c
泌 n
附川1川in
decre
ふa
剖i
均c
凶 d品川'"制I:l
l
.
' y‘山
l1dc
I i
1niじu川1 1
l
川llp
r代
叩υ、1
《】
凶 (
'11
1ピ引川
n1
η
tοf注5 0
ι A
.w
ル hi!c1 5.
4
宅,f r cportcdιl i ni c
al
improvcm c nl( ¥
rill足i
l cl
yI x: tw cen25 弘 a nd49Q.l nt hct otalgr ou p.66.7号 同 叩 印l
月 dcnl 倍
rcpo
r lcd;'
:25 め'
rh nprnvcl1lcn ti na n.
xi cty.I nt h cCESo n[ ygr oup( nomcdkati on ,s1
57.
7各 r cportc dd叫 r ca同 d川 l :
:i
l
¥ dya nddi nic alimpr o町 me nlnr2:5 OCkwh ile1 5.4%
rcport cddi n k.llimp ro町 制 c n to fa n則 c tvhClw ccn2宅待 a nl49r kf orat 刷、lIof7 J.IS 手o f
'0叩o nd enl swt lor eporlc lk !> sanx i clyandcl i
nkali mpr o
v cm..
:nl: ?:
25守 1 1Ih cCES
日ndmcukationsgmup.4~ . 2ιk o fre .
>
:pon dじI H'r
!c p叫 【 山 1uu:r c
u:>.cdanx icty礼n ddinkal
川 lprovernl!nt<:
!5()ψwhi e2.
l 16役 目 pOr l
eudc cr ..
:used川 XI <:ly2 5保 49C jri mpr o v 印刷"
te
)rHt oti
llo f6 4.Xr
/o
" fI'csp on u叩 tswho山 p川 I ..:
ddc c rca scdanxi ct
ylil叫 dini c al
impr ov cmc nt.<
:1 jtI
r,
PT5D( 1
1=忠 則 orI h
..
:t olalg r oup.J8.6ti ;r C[l()r!c dl e問 ‘mXIじt y・ mddini じuli m
p r o vclIll:m
of2:5ut kwhl ic2 -
'.9句 r cp orlc dclini ca llm rro v cm cll I( )
fnnxi clyhclwccn2 5~ル nnd 49弘
10Ihc1 011
01g ro up.62.りをr
5 espom lenl s陀 p or lc d. <
:2 5/完 I np rovc r
n entina nλicty
.1 0I hc
CESo nlyg r ou]l(noI lC
l d[
('aIIon叫 5 0. 0毎 日 p orl..:dd c c陀 a日 da n',
.ピt
j yan dc i
1ni c al
impro vcll
l cllIo f:
?50'
-:twh
- il
c2 2
.2<.
1:r cportc d¥ '.linI'a
L limprovcmel ll01山 政 i e
lyh c tw el!n
U~c r :
JI
lJU
":
:ly 出lXiel)
'an dcli nk: lIimp rnvc mc nt0 '
12'50筑 a tteru ~i ll g Al pha-Sl im.whi l
e1 2.66ちゅ
Surve
v. rClo
J nc dlt:
:
日・t 川 i ctya ll
di lllprovcl l
lcl lh叫 w ce n25 鴨 川 d 49写会ミ t ot
alo r1 :
N.8'
"% o f
1995- theseT山 ponclen ls同 por led<:!15~f. i mp ro
¥'em.
.:nti na n x it !t
y
199日刊 '
,¥
n.xidy(Wi lhu lh crt:ondit I
o¥, n=J
l
) 70 .0'1lhi
..
.gr lJujl,68. 1 1 'ii日戸川 ~J 1cぬ品 n xiclyall d
clin
icalimp ro vclTlcnl()fo:50( ka ftcrlIs i
ngA lph !
¥-S I
II l
l,w hile2.2. 97'hr
" el
川 円 以1 I
css
川 目ictyandi 川 p rnvcmCl I1belwc~n 1 5q‘ md-49t k.At Ql
alof91 .0忠弘 o f1 1山 C
r!.
l-:
pondcntsr c pufl cd:
?2 弓係 1 I11r
] o官
、mC1 li
1 1J
l n'
<ic
. ty . An xic t
y( wil hu cprc州 市 川 n=弓 お
Of th附 group. 62. 07匂 rcp orl coI c~s a n
xiely‘II1dCI川 ' C川 I mpr n、C
円 J
llClllof主計 )'ka f
lcr
山 川g /
¥lpha-SlItn,wh l
ic32 .767 .
.r c刊 岡 山1 .Icssi ln
x i
cl y~lO ù i
mp r ov cmcnllx 'lwccn25 ~是
anl-49与 を Al o tal of9
"'. 83t
;{,oft hesc町 、[l(.ndcnl.
.n: po r
tcd;
;日間 I Inprov 創n cnl
lll
anx;cly
.5 1陀 同 N=1 2 ~. O fl hisg rullp.7 0.73% r c po r tl!dlc出 anx iclylIndc li
nic:¥
1
imp rovcmen t0 1詮弓O俳 誌r tcr1刈 ng八I p
ha・Stil1.w
l h
i l e2 4 .39切 r epol1eJl ,.sun刈 etya!ld
c
imp rovemen th ct wccn2 50 ,
iω d斗 9C ,Al
f. utal01 円 12%o rthc同 r cs pond c
nlぉ r!p
l l
l山 d
;
>
:150;
:i m proVt!menli na nxict y
OL:ll
penlat
x
.
'l:PTSD:pll~Hrallm ;I(i l" ~tre日 dì sord c r: PSS-
I:PTSDメymptom刈 .
l
lcI
1
It
t"V陀 W、 n=1
'
l 984f
(l
rli
lX.i
clyn
pCI
Ilahe
Jω叫 メ u
rvc
ys l([ d i c~ 百1.1
0
n=257りti
xa lCESa
J nxi
ctvはu dic s
t
Olalnumberofsubjccts(
n)f
oral
1anxiety刈udicswas4819 ThcJ
'c have bcen lwo s
urvcys and onc open l
ahelcasc
wilh595fromRC丁
、 S
じnc沿t
oevaluatetheer
rcct
soft
reatingpos
ttraumaticsl
rcs
s
TherearenineRCTsshowingt
hatCESha
sprov
ent
obea d;
sordcr(PTSD)wilhCES.Thecases
eri
es1
山 l
edfor4weeks
sar
candc
ffc
cti
vct
rca
ltn
Cntf
oranxiclywithe
ffc
cts
ize呉 rang- 川 l
dpro
vidcdaver
ylar
gec
ffe
c ze(d;1
lsi .61)Ni
lh叫at
ist
ica
l 、
i d=
ng from medium ( ー0.41) 10 very large (d;一1.60)日 附 pく 0.05)日 Twop
signitkance ( ati
entぉ rcported ぬ 38 %and
Thr
eeoft
hest
udiesl
ookcda
tacuteanxi
ety
.suchasprcoper
- 34% reduct
ion. r
espcctivel
y.;
1
1I SD Sympl
hc PT Om Sc"le
a
tiv
canxi
e pく 0.
ty( 05
.d=
=-0.88).includinganxietypriort
o I
nter
vic¥V.Thecas
l!ser
iesr
t
:!s s
ul
t.werefurtherslIpportcdby
dcn
tal procedure民 (
1'; 0.02.1';-0.61
)
. Anothcrl
halmoni- the sur
vcy datat
hat誌howed64% and 39% ofr
espondents
toredchang
esi
nEEGmappingfcvcaledsigni
f
lcan
tchanges reponingc
1inicalimprovcmcnl0'
1~5 09;-' .fol When lookinga
t
ductoCESont hckftandr
ights
idcofthebr
aini
nthcal provcmcn.
clinkalim t lhe highcstcalegory i
s ‘日 t
bst
anl
ial
and0
:2rC立1
011品 川 知 子J c
lini iじhi
calimportancc" wh inedas~50IÆ.I 削
sdet
TheE
vol
uti
ono
fCr
ania
lEl
ect
rot
her
apySt
imu
lat
ion 1
99
TABlE19.
3
ルlet
a-A
nalys
eso
f仁E
SSl
udi
eso
fAnxiety
p
rin
cip
al
In vesti~ator T
ot
aln Subje cts S
ludyType F
indi ngs
K i r~t' h 山 ld 2
04リ 41s lud陀~ I.'xa1
1lI
nc d MCla
- Thc川 川 l ysis01r
' cm Jcrcdd 川:
.tunIh 'd
l
. kcl ofCESo n羽n .x
ict yyÎdd~J 泊 n dkus iz
c
Gi l llla<~' t
hcd f
c('to fCES a
nal
y川 lf
( r =0 .
57:ab rgcc fkct~ilC i
s副 知 W八 n alvs
is川 l hc~ lU dicぉ Ih :11 1l叫d onlya
U
l
la nxle!y uOtlbl c
-bindmcl h山 Ipro JL
にc dand r
...c
lI Ct
叫 u
rCESU la
I nxi ctyりr r =0 .53
.S l
u uI
!s
t
that u~cd cx
trancou st nc
an reso
,
> f:1l
t x
iCl
yw e印 陀 刊ov cd3 1叫 o nly叫l ldi出 fo rsta
tc01
tr
aita n
xictylha
lU 日 d Ih
(
'S pic
l h
cr:
g crSt
ate バn d
tInvcllt!町w c n
::川 a !y7.l'
u.T hじ
cffccl 川 C ES
υns tal
c札口 x
iClyw asr =0引}川l .
!Intit
:l1x
I ictyw r 悩 =O .6
H. W hcnt he
ほお ultお o
fu n‘t
[、
y刈w品 c orrcclc
df nrt h
cl111 mDcrur州 l、I
j
CL't
si nc a.
.:hs ludy.s ta
tc
l
11tlcty、川凶 r=0 .5 9a nulr
ait<ln
xicty、va
. sr =0.60.T hcc O'cじt SIZ
C.
< 巳f l
lrt h
c~ [
ぉw di出 i nthi
sm cta -a
n aly
.
¥isr a
ngeuf r
omh igh.)伽 tol ow6 恥
Kl
a鴨川 n..¥
.
y 2
41 日R CT .DB. CES MCla Thepi凶 [ eur c
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lf orl hccigh ts
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talizedpa ti
entsexpe-
c!1c cts ize (J~ 0 .54.p~ 0 .02)."訓 Thct hi
rd RCT d idn ot n叩 cedp aininthelastdayso fthc
irilveswith50%ー75%of
r cp ortc ffects izcsb utd ids ees igni.
i
f cantimprovementu tday pati
cntsdyingofc a
ncc rreponingmoderatet o時 v erepは)n
.74
1( 1
'~ 0 .04)andday4( I=0
f .03)d uringr hes t
u dy.Thes tu dy Tabl e1 9.
9i ncfudess evend ou b1e- b
1i n
dRCT s
.oncopen-
d e signc a ll
e df or5c o nsecutivcday so fCESt r eatmen tinun labcl,and t wo u scrs ur
vc y話 inve stigatingl hce fticac
y of
a t temp ttoimprov es lee pamonga ctived utyServi ccMembers treatingc hron icpa i
nw ithCES.Thct ota!nfromt hispain
A f ter5day日 o ftre atm e
nt,t hes u
b jectお intheacti v
egroup以 IW rcseare his1 7 1
2w ith366fromd oub1 e-blindRCTs
an品 、: r
agc0' 143morcm inut山 0 1s
' leeppe rnightcomparcdt o ThcRCTsi ncludcdp川 Icntss u
f fcringwi l
hf ibror
nyalgi
a.
19mi n1esss leepoverr hosc5da yぉ int hes hamt re川e dg roup .1
J Par kinぉon's,ands pinalcor dinjuri出 A 11reportcde rFectsiz
es
Thel hrees eparateus crsUfve ysr ea chedsub 叫a lHialclini- weremeasureda sl a
r gew ithp- val uesra n
g ingf romp=0 .03
ca limportancci n65%,58%.and45%o finsomniap aticl1ts rop<0 .001. Mosto fr h
ed oublc-b 1inds tudiesaddcda nopen-
Thc1 0wcr叫 : or eo f45%i sfroma刊 r v
eygi vent oS erviじC label arma tt h
ecndoft hed o ublc -
bl indp ortionins ham
Membersandv etera ns
.wh icha ret ypical
lyamo r
eu i
fficult treated叩 b jec ts$0t hatallp arti c
i panrshadano pp
or tu
nity
p o pul ationt ot re
a .T
1 hcm cta-a nal ysisgroup ed t her e民u1tぉ tor cceivct re atm
ent.l neach仁a s e, 州防 e ctsi ntheopen- Iab
el
from20insomnias tudi出 .e ncompassing 1 087p叫 l ent吋 anct plta児 alぉoa c hieveds ign
ificantp ainr elief( s
eeT ablc1 9
.9)
repor tcdalarg~ c ffe cts iz
c0'1O .64.('
t
l Ther e
sultsf rorntwod ifferen
ts ur v
eysi nc
ludeds u
bstanti
al
A RCTf oc ll
singon t hes leepin gh abit
soff ibromyal gia clinic
alimportance( ミ 50%i mprov山 1 1Cn
t)i npaticntswithpain
p at lcntぉ showcd s igni
tiじa ntc linical improv ementd uri ng (30%).headaeheち ( 4
0 %).rcf
le xs ympa rheticd ysrrophy( 5
3係),
ther igiddouble -blindp ortiono ft hes t
udy.l henevenheHe f Hbr or
ny al
g ia(54~), andm igrainch叫 da ehes( 5
7%).'‘Asw ith
202 Bioelectromagnet
icandSubt
leEner
gyM edi
cine
TABlE19.
6
CranialElectrotherapyStimulalion(
仁 ES)InsomniaStudies
P
rinc
ipal
I
nve
stig
ator n Su
bje
cts St
udyTypc MeasurementS臼 l
es/
Outcomcs
Pr
I:e
l
. /
1
, 130 S
Ci vi li a l\ ~.c
r ¥
'ke Su
rve
y 7
- p
o;1I1Lik !r
l ts c"l
e.Ofl ht!1()lal.
g roup. 57
.5後 陀 pim eJI 出 品 川 岬 mn 凶 anucli
nic al
M ctllbc:: r~ and 川lpro v巴 menl(Jfミ50野 ( I
Inp r ov'm叩 1
t
. orsubslani
l川仁 lini:
.a
¥imp u刊 誌nccc:
lIcgo可
VI
!l
. C ranSwi th Dwor bnd礼 !“) .whi l
c20. 4tkr cpOlt cJc l
inka limprov cm じn
l0' 1Insomniahe twccn
l
ns omnw 2刊 : lnd4 917
0( impr o ¥'cmcnlo fm ode r ateclini山 1i
mpl.
.lrW恥 :
c).IIt heIOta
lg roup.
77H .{
/
r )f山)<, pomkntsn :
:por teJ2: 25c
kl c出 川 崎 mniaa ndc l
iniealimpruv cm叩 tw i
thth
e
maj
or it :5
yofth csc 同 .~ po ndè nts 問 porlÎ ng :
2 (
Yki mpro¥
' cmentini n
s omn
ia
Lundea
仁i
ragn
a
u
n
d
i
η
57
I
n同 I
I
DUl
I
nt!
:
yS
c
A ~ l i v\!
McmbcrswI
t
r
h
vI
ce RCT.Ds P
i
ト
(
;
u沿b
4
lep
u
3min
rg1 r1 ~ ú l1l ni ;l Ra
)f
.Thcui
t
r utl
o" c
、
lhaci
陀
I l I:
.
ln
Cb
t
ingSca
ct
el
ha
we
nt
lc
:Th
h
ent
cs
eact
hamCE
hea、
ct
i'
、
ivcCESg
!g
eCESa
'山 I
n
r
oupha
pwhoa
dSh
‘
v
da1
!r
amCESg
a
g
0ng
e1
r
crt
9mi
oup品a
ota
ltimc沿J
nk阿 t
円lr
ot
oil¥:h
e
pt
alt
eu
irn
c
-
;igni t
i
ca n c e(p三('-079) .A. gcnu口 dit
Tc陀 I
1"C¥
l ¥
';附 o(
)lc
d.Mc nwhocompl c
tcdi l'
¥c
‘cs点目。nおり rCESh "dおign ilkan
ti mprovcmen ti ntolll
< tim
es kpぺarterIh 、
e針rICES
tr
catmcn t(p=0. 0 4
)a nJ01da y4
-(1'=0.U3) .Mc ninthc;H
.
:tiv
eCESg rnup可1 刊日 n
,
avct:
.lge(1f5~ O1i nmo rct 山 11times
leptaftctthei lrs
tCESt r
eatmenta ndn n川 口 a ge
61minmurct叫 ult il
ll
.'SkPl山 】 day4COOl川、r
I c dlOt hcshamCES: gr
oLip.The rcwcrc
nos igniti c a ntc h an gc鈴 i
nt ota
lt im
c寸e ptam lln.
gt hcfcmaksi n山 es tudy
Ta
yJo
rct品[
.
'1 46 ドihmll
y:
l.
igi
a 民CT.D
tl Gen er
alSle巴PD 、
itu
rhanピf'Scal
e(GSDS):CEミg rlU
( pha u訓 gniti
cant
lylo
wc l刈 I
) r
cson
P:
ni
cnls GSDS( i
ndkatiogIいおお kc pJi
泊urha町 c)t
h川 ぉhamfrom ha seli
ncatcnJpoinl(lf
‘tudy(p=O. O
OI( 1=-0. 30)a
可 ndcomplelc
Jtheぉt
udyw ilh!oc
' nre
shelowthcr'
,mg.
.
::of
1
1lS0nmJa
Lidl
lhr
oUI
1 (
バ) Fihrumya
lgi
a RCT.D日、 0-10Nu m
..
::r
ic
alRlti
ngおじ:.ll ,
c(NRS) :CESgmuphaJ"
Sig
nil
ica
ntlyh
igh
cf語以 '刊 誌 川 1t
h:
.
c
taL'ト Pai
tcnls OL qual
ityofsle
cpontc
:om
. emè a~叩 re t
hant
hl
!s
. h
arna
ndじ制1Imlgroup
satcndpoil1tof
当tuu
y(p=O. r2,d=0.
J 54
)
K
irs
dlc
t川 " 98 Scr vi
c t 'Me mbcrs Sur
vcv Lik
7 ~po î nl .
.:
:rtsc:.
¥l
c:~)f l 1
lcl o
lalg mu .4
p 4.8ck閃 portcJl e揺ら m叩 mn iaa ndd inica l
Jn
: dVcl er a
nswith improv e ll1c ntI)f~5 0' 令 whi le 20. 4f
Ar cportl
!dd inω
:..
1i rnp 、
roemen to fi l詩o
1 mr la
In~引 l tlln li\ 以::t
we .n2Sf
: 万lin J49( j.1
f ¥I
1 hcl ol algruup.6弓2 i
1砂川 町 甲 山u l
eJll 品目 似J r
ted2 :
2 ミ句
unp rn\'e m..:川川川 ~o lll l\ i a . InthcCESon lyg r oup(1
¥0Illcdi cat ion吋 .62( 手 r
j ep 1
0l cd
decre:
<脳c di nswnni 品 川 Jc li nI
.:a
li mpmv cmcnllfお O係 whi k23. 8寝 間 p urtcdC I山 山1
il
l1provcmc l
ll¥lfi1s
l omni abdwccll2 弓鴨 川 d4 )'
1 kforat ota lo fg5日係 υr",只 p on JCl
l
ts
whor c po川 c Jlc州 m詩O sl ni aan dc link alImpnweme l2
l
¥ :25%.I nI heCES) ;nd
mcdicatinm, gmup、- HJ.JC ふu frc)p
,
< ondcntsr Clo
[ rlcddecrc a叫 di n討o mniaa ndcl i
nIl
.:
al
rm pro刊 m創刊 当日9 ('wh ile1 9汚c;r CJ
10rt
ピdd 叩 ,.出 edi n込o mnia25弘 -4 9(,
Yoil
l1provemen
t
forat ul alof5 Y.8c
A : υrr cぉpu nuen tswhnn :
:purtcJuc c
r c
山 c Ji n ~olll n ia :
lndιilni cal
imp rl
lVC mC lI
J ~25 (;砕
A
1ph仕 Slil
l
l 1
63 I
nsomni
aPat
;cnl
S Sur
ve)
' -poimL
4 ikcl1S C:l
le: oft h
時 grollJ
l. 65. 0.
Vk日 p(lr
' leJI c l
l
ls “
offima山 ddi nkal
U叫 rSurn:y
. imrrovemcnto f 之 50~f , whi1
c' 28民 .¥tifrcpor
tcdI c 山 川sOl
llnIaa ndImpro何c
、 l
ll
cnl
199汚-1998 hCl¥v
ee
-n2 5 ~f :
tnd4 ~リ%八 l ot alo r 9 3.H7得。 ft he討e r山仰 ndenls r
epurl
cu詮2 5ck
nnpro山 mc n tin1附 O !
ll
lll
<J
RCT
'ra
nd(
)IlI
l z
edc
ont
rolc
us h1
wuy:DB:dυu ch
lind OL
:opc
nIL
‘ h
cl
:n=6句4f~)r ali
守 川 t
川lIli
ast
udi
c誌
TABlE19.7
Meta-AnalysisofCESStudiesofInsomnia
P
rincip
allnvest
ig a
tor n Subjects StudyTyp
e Mea
surcmentS
cal
es/
Fin
din
gs
;附 cha
K nJGilul
a仙 1
087 20Stu
dばお lhatexaminc
d Mcta~anal y 叫 is Twcl l
ty( 20)は u di
cs.whi chIncJudcJ1 08 7pati
ent兵 wc陀 an
alY 7eJ10
t
hceffe
ctofCESon dc t
enni nct hee fιc
l
f tofCE! 'o
i ninso
llmI aprouκ
ue danclTe
ct語版 eo f
msのmm a r=0. 64J eli n eda.
sal :
ugcc ITcl
.'
1siz
c( p.11計 約 N叫 己 ^mc ta
‘lIla
ly川 byHuc do-Mc uina:U
l dω l
Ie a
,
-t
'1I
CS(2012)川 theelfc.
.
:t01
100- 淀 川z
1 n di a zcpinehypn 州 国 t h
atindu le
t
. d円 吋 ud叫 invll
C ving
-1 17 民 ~ u hjc c! s pro
du ccdn“誌i gnil
ica
nt. hut忌malltomcdium
d;町ι陀 nc c
'.0 11s ub
jc!
':l
ivc討lccpl a
tency( -0.33)and
poly
somnn
grap
hicぉ1
ccp1at
ClC
YclTc
ctt
-0.
3刷 i
nfa
Vl
l"
ioft
hc
Ir
catm
entve目ust
hecOl
1tr
oJgwup
TheEvol
uti
ono
fCrani
a
lEl
ect
rol
herapyS
tim
ula
tion 203
TABlE19.
8
CES5tudyofInsomniai
nHorses
P
rin口 p
aJl
nve
sti
gat
or n Su
hje
cts S
ludyT
ypc Measureme nlS caJes /Outcome s
C e.
lilf.
l t;
: ¥
1
.7; 持 ( )Hor..e~. 1Mω2 OL Thじ p Hl p Ol1ioll0 '
11ime~penl s lalHl ing! tu zin glhr ough oUIth ef o urtr
Iu l p
h出 じ 討
:
.
l
I1d5Gddi
n;:
見 W: I
メI lJ
I I
Fc d .11r h山 e th陀c.v a lu c ぉa 'e
l h i
g h
c '0
l 'c
1 l)
凶<11t
ut hc柄。 lucsin酬 は同
町l e
.AP 山町t.l lI
- oln unp aringI hem: c anV Jl u
ピS duin
r gI h
e 心 p
、 h a
seso n
e. md
【hrcc~ ug gω I s l hedi I
Tcre nc
ci i
気持 gni li
<:anl( t=- 2ふ. J.p<O .
U 町 I np h国 efo ur
Ihe刊 met r
el 叫1 おお ccnw ithc achh 刊 誌C 、 刊l u
eh igher( n=o)01 'cqu i
l
l( n
::
:2 )
1ll
!
, h,11i np h出 co ne.Ap a
ircdt - l è ~1 ι onlirm~ lhじ見 i g
niliじa 1ι
l eu fl
hi>
!t.li
lTe
renじC
(
1=-1 .29. 1<0 .0訂
Thcp r o p o ri
t山l ofli mcぉp cnl河川以l ingd 山lIlg 配 r o日 t hep h 山出 w asa l
sof ou nd
10h :
:Wept)~i tî vc c orrcla Io
l nw itht rialp ha 同 (rニ n .
220 .p=り山.1) .t i
llc只pcnt
wi t
hl te 附 rlirr c l
a xeJ( r:0 .62 0 、ρ< 0,(則1).l im cS pClltwi 山 l o weril p
q u
ivcr i n g(1'= 0.48 4
.P<(J.(川 1 ). I hcI Imc. :pc
nt witht h eIc
f.e
l tr
; had .
れ =0 .2 6ミ ρ=f U)0 2) Imc見
1 pt:n lwi thI Ic
l ri
ghle arh ack(1'= 0 .26呂、ρ:::O.
(Jf日).
an dh c a d、',o hhli ngI士r0 ..
15 3.'<り(x)1
1 .)Timじ ~rcnl ~land i ll g l
to/ingaじrosお
thel ri
alp ha丸山町l~ a hof ounJt oh ~1 吋 a n e.
galivec orr el山川 w ithtirnesp目立
は andi l1 g 川 ~rl (
1'= -0.94汚 ρ<0 . 0 01)、¥IJn c話pcnle 山 n gb cd di ng1 "=
1 ーイ 1
.205 、
p:0 .
( 5 ).a ndt i mcメp CJll叫 li
ngf or agl!(r= --0.3 31.1 1<r u則1 )
ECES+Med
c
王
〈子
TG
0
%
2
0.2
%
21
.6崎
2
0Qも
4
6
4
3
40 ~ 。
.
.
5
%
2
%
6加も
,
~肌,
6
6.%川 =7
7 6
8
0帖
N=5
7
1
00怖
C
E5 1
5.4
% I 5
7.7
% I73
.1
軸, N=
19
7
•
2
3.9% 3
8.1
6
拍 • 6
2仇 N=55
T
G
2
4.3
% 3
5.7% 60
.0%
,N=4
2
ロ
巴
ロ
司 CES+Med
C
E5 2
2.略│
2 5
0.0
'
l色 I72.2%,N=13
T
2
0.4
% 4
4.8
% • 6
5.2
%,N=臼
E
C
c
EEES+MTed
例
帆 G 1
9.5
% .
4O3 d台 .59.8
%,N=4
6
仁E
5 2
3.8
% 6
2.0
叫 I85.
8帖.
N=1
8
1
8.0
% 3
6.0% 5
4.0
%,Nニ 4
8
E
ω
v
C
E
口、
L C
ES+
MTe
G
d 1
7.
1% 3
5.5% -
526%
,NZ4
40
仁E
5 2
3.0% 3
7.8
% I60.8%,N=8
口I
mpr
ove
d25-
49% 口I
mpr
ove
d之5
01も
T
G=T
ota
lgr
oup,C
ES+Me
d=仁日 n
ial
ele
ctr
othe
rap
yst
imu
lat
ionpl
usmedi
ca
tlo
n
lGURE1
F 9.4 S目
erv
川1ω
じ oM山I
己m
口 h
由児
、C
町r
aωn
dVe
叫 剖I
c
町ra
n沿以川I
I
r
円v心yc
omp
a山1
川ng出
1
hcm、
Co
心 fC
f
江r
山u
刷i
川
l a
1c
I叫 Je
clr
o
叫【h
cra
py誌~吋‘刊t i mu l ation (
CES)"川お t
:
;~、山、
me
出1
1
】1tοCESwi
th川nc
"児dicat
io nぉ
204 Bioelectromagneti(and Subtle EnergyMedi口 ne
TABLE1
9.9
CranialElectrotherapyStimulation(
仁 ES)RandomizedControlledStudy (RCT) ,
SurveysandO pen-LabelStudiesofPain
P
rin
cip
all
nves
tigal
or n Sub
jec
ts Design Mcasurement$cal
cs/Ou
tcomes
Tayl
orC
I<ll.~吋 4" Fihwmyalgia RCT
.日8 0-¥0N¥{S
:Thoぽ in
Jivi
ou;
¥lぉusingthca
Cli
veCESc kviceh:ld,
¥signi
fi
can
t
Pati
c!
l{s JCC
fca
scin山 cr
agcp川 1(p=O JJ23
)whcncumpared1 0th出 ci nd
ivio
uals
Uおi
ngthcshamdc、i
ccorthosじ r
cco、
:J
. 1
1
lgu討u;11car
calonc(Jvcrtim
c
。持fthcBP1
Ta1
lc¥~p同 1
05 かl
il
C
on
i
t
l
l
a
n
r
y,S
j
ur
p
y
in
al
。
Rι:T.D日
L
唱 {ー1
ト
a
0NRS:P
ainJ
n
山 町 CESg
te
nsi
tvan
dPa
i
.r
nJ
o
n
u
te
r
pr
f
cn
:
cp
:l
o
比:
r
cSuhsc:
t ,
吋 ai
dc
gni
tica
n t
lyg r
calc川 町 四 euccr
四日 m
:The
p
;:1l1l
p rc1 0po 式t daliyt
r:a
l lmcn!ぉ Ih
ant h
es h¥
'
:1
T1gr J(P<(
ou[ ).0
5).Thea c
ti¥'
eCES
g r oupぉh叫 cdl arg
erp r
e -10po仲 l日 山llcntd町出品山 i npainin
terlCrcm:e
thant h 、c hamg roupd id(JI<0.0
1.d=0. 59)
.Thじ;ぽtivcCESgwuph ada
~ igniti t: ant m cal
1p川 11J¥t
叫 訓 yJccr
ea:-eo f0.
601川 i
ntsunthc
:(ト1 0おじ a
le
(1'<0 . 0 01.d= =0.7
3 )
R
inl川,
¥ct泊 1" 1
3 VCI
C 日 n!
'
. RCT.DB 0
-11
1NRS:SubjCCbr
ecc
ivin
gcti
w CESh
od,on 川 ('ra~ょc. a1
l 泊 .
14戸
、Jl1
!
Pi
¥rkin且0"冶 dじ じ 問 削C川 p
a¥Oκom1旧 日 dwi
lhaO
.23
-pいi
ntdc..:rCil ~e f
ort
hos
c向 山 lvmg
Di ~eal気C 気hamCES(p= =0.(28)
Ta
l
lcla.
l'
" 38 Mili
lar
y.Spin
al RCT.DB u.
.JONRS:A ctIvcCESgmuph山 1s igni恥 川t l
ylc同 pmnt rll
Cnslly,pn
.'( Upo叫
CurdJnj
uη OL CES刈 判 l on.comp a 陀 d10sh all
lg ro up(JI=0.03.d=0. 76)
.At :1仇'cCES
吾川町、 r cpol
1cds i
g n
if i
cantl
ydcc印 刷c dpninintc
rfcr'
llt:じむ1=0α旧、
d=Oミ0 ).prev er
.;u謁 postinl cr
vcntinn.w hi
le1 h
erew出 anon誌i gnitic
alll
dcc日 出ei np a
ini ntcrfcrcn
cl"i
. nth巴 対 hamCESg roup、旬r cvc r見Uお pO~I
l
I1t
c円 enlIon
.OpenL abclg!'(lUphad討 i gn
llh
:antl
yl e品 pam1 n【 叩 叫y片山n
ha叫 l
inc1 υcndpointo fs tuuy(p=0 .(3)
Cork い 74 ドi
hrn
rnva
l1
!ia RCT.DB. 0
寸 NRS:A cti 刊 C ESg rυuphad気i gnit
ica
nllylc持活 p
.1I1Hll
I c
l川 tycomp 川
-cd
Pat
ien
ls OL 0~ha m gr
1 oupa le n
upninl0'1stl
1dy(p<0 .(
1).NRS,0-1 0:Activ eCES
grouph出 l owerlc l叫crp Oln
l叫 O刊誌 compJfcd1 0品 川 1group(p=0 .0
1)
McGil:No詩i
l g
nitic
antu iff
crenceinpaInぉCO'
lCSh e
tw(!cl
1A C
li v
eCES剖1<1
Shamgrnup~. ( ト5NRS:Op '
.
lnLa hc
lg rouphad訓忌 n i
liピ
D.l1
11
yd t,(!出 l
SCjl
.l
l
rl
f'
ll
ll
l
lh:lsc
lin c10emlp llin
tIlf),Ud
l y(p<0 .
1川 11.M正G ill
:O pcllL油 dg rouJ
l
h川 叫g.llIf
ll
'i1川 1'
)dlXre山 cdPilinrr
mnb a
珂 li
neltI帥dい> 1
1
11u f剖 m ly
(
1'< り0 (1)
Li c hfhrou n :~ “ Fihmmya l
gia マ DIl.ト lUNRS:-
R( nl
cU C【iv
cCESgr uuph ad...i
gn
ili
c川 Ilyl o¥V:rp
t
: ain" co刊 お
Pat
icn
tぉ OLρ ~ O.(X】2.d = ベ16訂 l uwc r I cndcrpoi川 町 山' ¥'
S(p= =0 .01.tl=0. 36】 hi ghcr
qualilyor符kcp真cur e
s(p=0 .01.1=り 4町 h igh crr cel川g
...orwcll - bcing
則。町語 I p=n同) 5,d=0 .7 31
.h i
g hcr吋uali
ly川 i lfc封 印 rい ρ{: .{). 0
3
d=0 .97),lowcrf3ligu
c討c orcst p=0 .0
3.d=. .
..
0.72)andl tl
wernng clぽ 何 引
('=0
1 .04.d=- {
).60)Ihant hes hama nuco n
lrυ!日 山 円 The0 戸 nl ah c
1
gr oupha Jsign
ificantga川、 o nt nt
c 1c
rpo in
ls corcs( 1'<0 .0(1)‘l1lUdc cn
.::as
cu
pa i
n(jl<O .n(5)fromb as dine1 0eni
Lpoill
lofsHlu y.Tht:l<cl
ivl
'CESg r o
up
anu叶 淀 川 clini
calCESg ro ph叫 a1
u 7('
/
t:n::d
lh
.:1
ill1i
l n世 lf-ra
lct
lp ai
n当仁川出
mula2 8Li
ふd e口四時 i nl ent
1erpo intsco
n :ぉ
Alpha-S
limU同 rSur
vcy
. 67
X RSD.Fihrom yal
gia SU' !y
lVl
. 5
- poin tL ikcnScalc:RビJlc xS ympath clicDy‘ Iwphy(RSDJ ,n=5 5
19
95.
..
.1J9
1 .
l
!1
完 川 dMi
!!
.l'.lIn
c Rωpnndemsreponedi mprvじmcnlofpain出「叫 I
o mv, .
;日 7Yk町 poncd
.
pa
tie
nts painr cilc'Jor2 :S{)
Ck.29.09切 r e
p ortcdp ainr c1icfhclwccn2弓 <rund49<:LA
.
!
lot
alu fRI .R2%( )
fr cぉponuentぉi'ep刷 .te
dp aillr clicfa ~ ;
::
:2
5切 刊わr omyalg i
‘l
(alon c).1=1 41.Rc ぉp o
mlc
nl:
->r cpo rlcdi mpr o v山 ncn
t llfp ail
l:.f
1
:
- ol [nw : -.
5~.52% ' le port cdιl
pi 11rei
lcfnf;:::50~. 37.nl 'hr epor
t edp :l
inr dicfh et wecn
25;
ti .i1n J4¥1偽^1 0la1(
11明)匁 5
' I
J.01 陀s
' pO ndc llbrcponcdpa i
nr d i cfa s
ミ25' 1十F i br omy alg川 ( w
ilhulhe r山 ndl ijoll
).11=' .63
.RC' -
:I
附 ""聞い陀(1 I
)r
l吋
lmprov~m叩 t 0 'pa in出 f olo¥
¥' 5 、4.S2'k叫抽l1e dpai nr c
licf01 J
、
1 '2: 弓却
O ~'Í'
TABlE19.9 (
εon
tin
ued
)
CranialE
lec
tro
therapyStimu
lat
ion(
CES
)Randomized仁o
ntr
oll
edS
t ,
udy(RCT)
SurveysandOpen-labelS
tud
ieso
fPain
pr
inc
ipa
lI n v e
slI
gat
or n S
ubj
ect
s De
sig
n M四 s
ure
men
tSc
ale
s/O
utc
ome
s
Ki
rsc
hcta l. ~ 1 1
43 P
ainPalkn
ls S
urw
)' 7
- p nInlL ikcl1町 . .I
c:P ain( 0=.1 ¥:
: J3 0'
1 ,uf t
hc1 01<11 gruupr cp oI1 '
l
,
.dd cじ 陀ι、 ¥
!d
Scrv
iccMI.!川札!
r
s p alll川 叫 c lin kali mp ro¥! emcn tof~日 OfÆ wh l
ie円 I <krep ot
r edd i nli'
al
andVl己r
¥
! an
沿 i m pl'¥J¥!cm elt
! hct柄、¥ !n25( 'ka nd4 9
('',
.
4 ¥l
; ot
alo f 45,J Ko
t ft otal gro up
I
X 11
l h': lpa
ntsu 山n .
gCESn .:p on¥ !
d2 :2 5
'kc l inic3.1 i l
l1pro、ωl1cn.tJ nl h
¥!CES
i Jl1l
yg roup( nom cdi cati ons)的1 .6
('A
.u fr cp
持 on de n tsr epo rl
edd 叫 陀 出c Jp a i
n
a n J< :1川 出l li m刊n vcml !n
.t2 : 25係 (46. 2"'
/(~50~;'t> . 1 5A~{ h
' ctれ川cen2 5 t
;ユn
,
十 d
4 9 匂 i lllpr
o¥'C 1
1lenf)w hil
c4 1.
7 (
4u ft hcC~雪 and Illed i catíon ~ g roupr e p
or t
ed
J e 口 同 誌c p削 1 a ndd i nka li mpro v
¥!llIcnt三2 SCi
ル( 26.74 '
#.:
;5 0り I
長 Ykh cl刊、c c
n
2 5%i1n J4 9;rfi mp l"u¥!erne
nt .Hl !ad ache( n=7 0) :4 0%o f lhel 01 al group
刊似)rtc dd c
n.
. :
:出 c up ain川 ddi n ka lI1
l1p rovcr nc nl or;:
:50 1
h:w hi1 cl H.6~
r
e 側、r l cJc1ini<:
alimpm 刊 m cnl h et WCCI12 5'
(fa
, n d4 -9c.0
k 1I
' hc1 0 la
lg roup
58 .6 '(
4-o fparti口 p antsr Cp ¥
lJ'lc
J2 :2 ベ%じIin ic礼1 im 、
p r o1じm cu1.InI hcCESo nly
gm u p( 10Illl!d
1 il!u
. tinns),](附 ' ko f陀 s p川 l dentr
見 cp o円c dd ccrclI!位以1 p
: In‘
1 lnd
にl in
i山l 川¥1'山町 n tc nt~25% ( 64,7 %2 :50' k.35司 7rh etwec n2 5 弘a nd4 }C
l イ
lll l
pr、Ci
1 Clll
cnt)w hilじ 45.Jf'A0 1I
' h cCESa n dm c di catinn詩 gmupr ¥
![ Il
> r
tcd
"Cピ' e 出ピ p ain3.n ddi nicali mp ro vemc nt主 ユ5 係 ( 32 .1 K:
' ;5 0%p a i
nr clief3.nd
1.¥'.2 'k陀p ort c
dTcl w山 n1 月 '*a n dt.9 俗 l lnpro 問問。l¥
H
lll
ub
!¥
じ 7 2
号 弓 P
ainP
‘山 じn
lS OL 1-1 0NRS弓2 弓(;0肉付¢じ UtlV じP 山 n pa l
lc川 s inap a inma na gcm cnld i niじw c r
c
a d m in iぉI crl
'd2 0m in0 1C
' ESt 問 a t me川 O rt ho~ピ 261 wcr eg iv enas ccorul
tr cat m c n
talt hci
rn c刻 、 isti,1 6
0¥ vcrcg i同 nt hrl 'Ctrl'ut
m cnt人莞 7I VC陀 g w cn
f ou rt reatmen ts.a n d2 6w c rc別、l entiv et rcatm e nt s.T he7 9,81~託、、 ho
rcs po n dcd¥1 1thct ir
sttr ca l mcntI!x pcricl1(,:edι 14 2.4 0%r c d
u ctiul 1in
持じl f -r aleJp ain.w i thラ 1 4%of th ep a tk n bd ecl a ri ngIh己yw cr cp ailf re
e
C u m ul a tivcr cs
ult 弘、刊刊 日' (1:Im
. ongIhúsc 持 uh~、cqucmly m' al cJ. T hcn!w a
:.
a7 0,il叫後 r edu ctIu
lli np 川n a
ftcr 、
it.'
cI 同 al I1lCJlI.~. includ
i ng1 弓3 " 告。 f thc
n ! mUlI1l sgp 陀aln lsr epol111gm lr ωn
H
ctk
rn、聞 齢す 3
0 C
hronicPa
il
l RCT
,DB 5
-p '
川 HL ik cr
tP a i
nS calc: Th..
::a c[ivcA II、 ha -
Sl i mCESg r ou
話ph r
ainwa vc
Patk
:n
t可 p al ¥cr nじh an gedf ["
(lm;
' mu n ¥
! ve
n .j aw- to othp al l crnc Ol
ls
i剣山t lw i[ hp ain[ 0a
、州u (
)lh: -.
pe
c l
r 川p a H l
!1
"lc
I o n州諸[I!nlw ithap ain!- h:cp al
tr:r
. n,T h ca じh、'cCES
g rol1p h.d
3 吋g l11片い川 t l
yI 日p
c :
l
ln,凶1I1C u
出 reL
Ih yt hc、1Cp
i oi1¥1 .i
l kcrtp ぬ"
'
~\,"Hlc t hanth cL issCES n砧 u(,;onlrol JじV¥じじ g ro u p s(p<0 .
011
[C
ミ T:
ran
L
Iomi
zc
dco
n[
ro
lt
ri
al;
DB:d
ouh
kh1m
i . OL
守
i :l)
凹 nl
ahc
l:N
RS:n
Ull1c
ri
ea
lra
tI
ngぉc
al
c:n'=3
66'
}
¥
I rRCT
s:1'= 1
341OLa
nd叩 r
叩 yお[
ud
i山 l
ol
al
n= 1
712f
ora
l
lCESp
:li
l対 u
dic 話
whilea lsoallowing甲 山 I O
U S‘CESd eviccs
"t h
utn ev
crrcgi
s- Overt hepωt d~(;ade . thaeh asbeenI n cre削 cdI ntl2r e s l
tere
dwi lhFDAt o1四 日oldo penlythroughmagazinea dsund ul
Idl l umcrou
s以 lv‘tn
ce si nt heu seo fthisa pp ro:
.c
J h,n o
tonly
webs
i tes.Co nvcr
sely,FDAa ppli
esa dvers
ee v
cnls.however with陀 s pe
ctt orTMSb uta ls ov agalnc rv
est irnlll ation , xo - ~B
mill
o r,cquallytoallCESd ev
icesthatじomplyw iththcFDA Pl
Ilsed日 g nalt hcrapy( PS T).w i dclyusedf ort hct rc叫 mcnt
def
init Io
n‘ and lim
its whut de vi
cem anufactur
e r
s andd i
s ofo st
c oart
hrit
isi nEurope.hasa lsobeenf o un dt ob ee f fe c-
lr
iburOI"smay泊 ya bollteffec
lsfromt h
cirIeg
allymarkcted li
ve,a nd.a lth
ougha v
ai l
a blei n20o therc ountr ies.l iiso n l y
devices,evenwhens Ic
l hs tatcme
nts山 ea ccur
uteandt rut
h- approvcdi ntheUSAf o
rv eterinaryu 日 制
fu
lr at herthanmis leadin
g.Theseando therproblemswith At t h
e V ctcrans A dm inist ration Medical C en teri n
the Centcr "orDevi
1 じC ぉa ndR adiologi
calHeaHh (CDRH) Clevel and,OH,USA,r h c 1I問 o fAlpha-Slim t c chno l o g y
approvalp rocessIsdiscussedi nChaptcr49. toIrea ttinnI
tuswase val uatedi natwoa ft1l expcr i
m e n t a l
叫u dy.!5Th
l et i
rstarmc o nsiste dofs cv en mulesandt hr e e
femalc~、 from 23t o69 y e ar
so ld(meano f43 y c ars)hav
lAlAPPL
OTHER POTENT lCAT
lONS [ngt tnn[t
l日 inat otalof1 8c ars.O to
l ogica1anda udiol og i -
('
a1e val u
atio
nsr evcaleda lls ubjeclse xceptonehadv ar yi ng
TI
NNITUS
d!
.grceso fscnsoryh eari ngl oss, Betweenoncand 1 7t r ea t -
Aぉ indica
tedinth!
.
!f ir
ste di
tiono fB iοel
eClrom a
gnelIc mcntsof50μAAlpha-Stimぉt im u
l a
tioJ1 W出 g ive na t1 3s it e s
Mιl i
cin
e.v a
rio
us formぉ 01
'crania
le le
ctri
cal ぉtimula
tio
r】 uroundI hecaff or24st o2m in.Thet inni
t uswasmatchcd
havebeenuscdtot
rca
tt i
nnit
us1'
0"o
1 ¥'c
r200y ea
rs.7<
J aflcrc acht reat
ment、、lit
hs imul 込tcdsoundsfromaNorwe討t
206 Bioelectromagnet
icandSub
tleEnergyMedi口 ne
SG- IT innil usS yn lhesi尻 町 l lsingana sc cndi ngp roc e du re.Six As igni白c antnumbero fs u
bje ctsreponedimprovemen ti n
01l h et en叩 b j e
ct sr epor teda tl eas ta60% improv emcnti n he a
ringa ctivi
tyh utI h
i前 couldn otbev er
ifiedb yob jective
山g hl0" 1t he1 8e ars‘心 011!"
irmedbyt innitusmat ching.Thrce cvalualioJ1.Thea u th
orsc oncludc dt h叫 t he82%s ucce日 r ate
addi tionals ub jectsw e n!u nd ecid edw het h c r improvement inimprovementi ntinni
tusi mpli es込 f easi
blet re
atmentp ro
hado c curre d.Thcpcrm川 e nじeo fi mp rovcl l
lcn tl as lcuf roITI cc d
u rci nl h
iぉo ftendevaslutin
gd isorde rthatc anp re
d ispos e
Xht o2 .mon l hs(Iastconl Hc Lwil ht hee xper im enl cr) tos ci
UJ dality
I nl hese cond山 111.20s u~j ec ts W口I'Cd ivide dI lltotwog roups , Ina n others malp ilots tu
dyo fi
fv epat ientst r
ealed、 .
vith
lna
i
. ctiveandac ontrolg roup.i nas ingleb J indp ro to coJ
.Al I Alpha- StilTIinau niversi
ty-basc dn e urotherapyc lin
iじ tlllnI-
川 bj ectsw e r cmah :
:,wi lhc ithernormalh ClIr
. ingo rs ensor y lusha nd ica pandt innit
uss~\'eri 旬、 as well‘ IS EEGp rcand
hcar in 呂Jos s‘1l10stha vingi di opathico rn o
is eexpo ぉu rctmllI- postm cas ures,were Llscd forb aseline and t re
atmento ut-
tus.Eachs ubje c
tr eceive dab aselinea u d
iol og ica le v al ua
t ion comcs .Ther ese
archersr e
po r
tedt hat40%oft hep art
i ci
p ants
utili z
i n
gs la ndardequipmc nlr efcr cncc dtoANSIs tan dard s (lhoscw ilhu nil
aleralt i
nnItusRuc t u
at ingini nt
ensi
t y)e vi-
01山 rc ond ucti oll,s p eechr ec eption thre~、 hold , 11l0 stCOIn- dencedapp陀 ci a
bleimpr ovemen ts川 t hcirtinnitussymptom誌
fortabl eI Olld nessl evel.s pee chd is cri min
a lion(W -
22word andt hatr eぉpOnSlVCI
1C同 tot r
ea t me
n ti nthiss ubgr oupmay
i
l叫 札 a ndwheni ndicn ted,bonecondu ion,i
ct n】peda nc cb at oc curase ar
lya ぉt h
et i
rsttr
catmcn ts eお1
お 0
11終偽
tery
.andt on ede c a
y .Thet re atmen tw出 i de nti calt ot heitrst A coじh learim planllh川 c anbe山 : l iv
atedwi t
hl owr
れ ate
annc xccpl lh ccu rren lwasa t50o r100μA.andt hes t imuluメ clcctri
cs timul川 io
n"was a tt!.! m
pted and appeared t o bc
Jura ti o
nwase ilher1 2o r24sa tt he1 3s I
les.A rt cre ‘.
H.
::
ht 陀 はt- ve ryc1 Tcctivcf orJe辻fp atientsw ithl in
n i
tu討 buti sp res-
ment .t hct innituお W出 a gaina naly zc dlIsingt h esamep r
o to- cntlycon traindi
catedi nothclぉ bccauseofaぉs ocialedn e r
v e
co.lThecon trolgrouphnd[ h eide nticalp ro ce durer epeate d daamm
aag
ge灯
lwic c ,thcn rs tti mcwi thoutト; timul atiol,r ollowcdbya ctllal
叫川1ll!a tiOI1. Of1 7e a rst reatedi nt heexper ime n
t alg roup .
仁
A、KE
r R
onlyones ubj ecl( bO lh出げの wcrep erceiv c da snOl h avin g
unpr 、
cvcdbys limul川 iOI1. Thus .n inco rt cn日 I hje cls( 90%) Thc ra hion icn onin vas ivc1 0¥V c nergye miss iont he rapy
corr eぉp ond in g1 01 5o f1 7即 日 ( 8R' i
b)r epor t edimprovement (LEET). a no therf orrno fc ra n
i ale lectrother apys ti mula
int h cirt i
n nitus .Thcdcc rca~也 in t innitusf r eq uenc y[ ort he t
10n、h asbc enf ou nd1 0bct hemoste ffectivet rcalmentf or
subj cctivcimprovcmentr angedfrom48%i nones uh jectt o hep atoccl lularc arc Inorn aはn dhasおhownpromi別 ngr es uぉ
t
1
cOl1lpleteremi s
sion( none)i nI hc別 xe a r
scombi nedf orf oul 川 c crti.l
JnI T
I elastatK m川 i i ‘
gnunc it
:s.There a re noa d v crse
subje clS.One s uhjcctd idn ot1 児 rc目v ea 1 9% dt .!c rcasca s sidcc ffecl s.andt hcd ailyt hree Ihs c持おionsc an bes el
t
hcin .
gs igni rican .
t111t hecon trolgroupo r15c ars.i no nlyone ad mi nist ereJa thOl Icwh
T ilct hcp atic
nli src a
d in go rwal ch-
eard idas ub jec tbelit!vet hcrchadbeena nychange , andmea ingt cl!
.
!vis ion附 句1
叫 r c mcnl長 i nd ic"le d"1 3係 d ecr eas einf r
e q ue nじy.Thcr a nge Nnvocur et UITI
ort ant ingf iel
ds(TTF)hasbCc !na
. pp r oved
01c
' hungef ort he1 5e arswasfrom+1 6‘(lf tcrs hams l Im
u la- byt heFDAf ortreatingg li ob
l aslOmam ultifo rmcandc ¥i n i
cal
tion,f requ enc ywasmcusured川 h ig h
e r)1 0-2 20AI
.Oncer he tri
a l白山じ i np rogres s1 0c x tcn dthiぉ tol ungじan じerandmeta
cOlllrol gro uphada じl ualsti l
l1
l1lation.S O f
C:,n
. :pO rl以 jI mpro ve- staticb rai nles ions
. '
1
2TTFt he rapyi sdeliveredu則 ngnonl1lv a
me nli na ll e‘目tonec 山 Th emcnsurcdde cr cas ei nt innitus 引v c,i ns ulatcdt rans duce ra rraysp l
accdd ircctlyonrh~ s kin
l印刷 c ncyr an gedfrom28% 1 0compl eler en 川 s i
on( none )i n arc as urr oundi ngt hctumori namannc rr h
ata llow ぉp alJentぉ
fOUI日I bjeはお tomai ntai nt heirnormuldai lya crivit
ieswh ilct reatingth~ir
Bccau話cb o thg ro up sint hcs ec onJarmha da ct uals tim u- di同 制c .WhilcI lh a sht ;cl
l日 f c
rr ed10山 “ 24 /7 CES, "TTF
lation.I hed ataw出 p oole d.O vcr a
l limprovementw川 82%川 the ra pydoc sn otd e livera n yel ec t
ricc urr
e nt1 0l hetiS Sll
C.
repo rtedby20s ubjecls( 2
7o f3 3e ars). Inte nc asc只. t herewas sti mulatt!n
. erv es.o rhea ttISS1IC
.R ather,i
tc reate sa na ltcr n
at-
じomp lc
ter e ingc lec
:t
. ricl ieldthmi nterr cn:ぉ wi thmitosiぉ andc cld iv ision
wi lhint het l1mo .Theon
r lys idee ff
cctsa r
eocca sionalぉk in
irritatiol
¥a tthet rans du ce rar rays ites
WhC1I 】crFDAc 1e arc dCESd cviceち mayhav ca n
tit uJnOl
effe ctsisn otyetknown.ai thoughan~cdota l r eport品,山 cha s
onep ubli shedi nth~ formo fabookbyMargar ctWa ddin gton.
MD.は r etiredn euro logi s
lw ithI ymphati じl eukemia‘s ug gcst
lhiお p ossibility.Hero ncol ogislg aveh eramaximum2 - ycm
pr ogno stぉi fs here fu日 dc hel l
lo lher込py.Ast hisbookg o e sto
prin li l
l川、 b eenove r20yea r ssinc cDr.Wadding tolr cf usud
ch emol he rap yandr eliedonel ect ri
call her
apyf o rhe ra pop-
tos ist reat mcnl.Y cts hei s叫 illa bll210liveal oneandcon ti nuc
hav ingap roductiv elif~ w h iler unn inga! Oラa c r
cmaplet ree
f ar mi 1Vennont同
P,官l im in礼r ystl1uie討 a1 sos upp ortt heu s
eo fCESi nca n
:c
r
. rp atien ts1 0r e
d uc eI h cs c quel aeo fradiationt herap yf or
TheE
vol
uti
ono
fCrani
a
lEl
ect
rot
her
apyS
tim
ula
tio
n 207
canc er
.l no nes tu
dy.t hea u t
hOiぉ c onclude dIhatI h
ec lini ca l inc a
c hi ndi
vi d
ua.
lA ftert h
ei n
iti
alt ri
al,pati en
t scanb epre-
tmpa同 i o
na tM.D.A nd erso llCancerC enteri sthatAlpha scribedaCESd evicet ousea thomeg i
vingthemi llcre
ased
Sti mt herapyiss i
milart oh y p
e rba ricoxygena ndb ot ho f controlo vcrt hcmanagemento ft hetrs ymp to ms.I na ddi-
Ihcsemoda J
ities制 定 achi evingad e greeo ftissuerep aira n d t io
nt o:1r egul山 20-60mint rea t
me ntdaily0 1e veryol h町
rcv山 山l ia
rizati
o nofthei rr込di atedn el
d.Al t
houghi li ss lIlI day,p at
i e
ntsc a
11addt reatm entsa sn eede
d .Somt !c1i nic
ians
undcarw hat日 s pec
ilicallyo ccur ringp hysiologic
allya ndh i s- tin
di tusefult Oscl upaCES l oungewhcrcp atientscan
tological
ly,thci rr
adiat
e dぉo fttissu eち appeartobecomcr ev. 山 comei nf o
ru n
attended1 0、
;vc ostt reatment 呉 whcnc vert hey
culari四 d.Iti sa p
parel1tt hattl日比 m odalitieぉh aver el ie v ed f ee
ls t
ressed.Thisc onceptwass tu d
ieda 【l heM ich aelE
diぉco m
fort.cnhancedh calingo fi rr adiut
edh arda nds oftt is- DcBakeyV ctcransAffairsM edicalC cnteri nH ousto n,TX,
sue丸 a ndi mprovcdt h
eq u alityo ft h eirraJiate
ds o
ftli おお ue s.<)~ USA.A fterb einglminedt o"s etived i
ffele nll yp
eso fs tre
ss
A 6 1
-year-old mak v etcmn r eceiving 6000 r adso f relievin
gd evicesataw alk -inp ainc li
n , v
iじ c ter an
sp ref e
rred
radia t
iont herapyb yam e gav oltc obalt1in cara cc
e lc rat o r Alph a-StimCES73%o ft het ime.Theb e ne
f i
lso b sclvcd
forT2NIMOs quumousc ellc arcin omHo fther ightt Oll日一 included improv 凶 叫t enda nce: 1ndv eteran s'i 1v
l ol vement
lara reaatt heCl e
velan dVAM cd icalCent crwasgi vcna i ng ro up-basedt he
rapies,r educ【iOl1sinr e portedp a Inand
maximumo f30minofAlpha-Stiml herapyo f50-500μA a nxicty‘i mproveds J
ecp.unda ni ncr
easeds enseo femo-
al0 .5H玄 immedi .
itt
dyf ol lowin ge a chradiationt r
e at me n t tio
n a
lw e ll-
be i
ngi nthep ar
t icipa
n t
s.D ecre a sesont he0-1 0
Thef ollowinga dvers
er eactio n
st or adi川iOI1weree x pe ct e d Num ericalR a t
ingS caleo fp ailli n
t e
nsityd uringt hes tudy
irrcvcrsib
lex crostomiil b
. eca usea llt hcs alivar
yg lan J s pcriodweres tati
stica
lly日 g0 1l
Icanta tpく 0 .001.はn dr e
p r
e-
we re induded i nt h
er acliat
ion l ie
1d.l emporar yd yぉg e u - sentedal ar
gee ff
cctsi尻e0 10
' .93刊
sia
.t hro
atp a in,possi b
lemuじO SltlS andr
司 adiat
i o
ndcrma
tI
tIs
.F ollowingl heCESt r
e alrnent s
.a l
la dvcrscre‘ IctlOns
were r e
du cedd r山c
a ally and x cr oslomia and dy sg cu s i a DURINGPSYCHOTHERAPYSESSIONS
werec liminated.Thcp a tientr e qu irednor egimeno fp a i n CESmaya lsobeuぉe ddllringp sy c
h otherapy括 州 o ns.Using
me dicationb cc a
llscCES r edu ce dt hcI cvclo fp ai ne a c h CESd uringat al
kt hcrapys essiond ecrci
ls
. eぉ un xi
e tyand
dayf ollowingr adia
tion:h eshowednos ign
so fIllu co s
i t i s usuallyi mpr
o vest hep a
tient"sd esireanda b
ilityt os hare
orr a d
iationdc rmat
itisa tanyt i mewhichi sh ighlyl In usu al p ro blems,c o
n cernsandworr ieswi ththet herapist
.a sw ell
a気 持 omcd egre e()
fx er osto miaandr nuco日tisisa nt
i ci pat ed a ぉl or c s
pondl ot het h
crapist'sq ucstionsmo rce ff
e c
tively
.
ina lls uchi rradia
tedp ati cnts.Thea ut
ho raddedt hat日 v - Ane cdotalr epo
rts from p syじhiatr
i s
ts. p討y cho logist
メ a nd
eraIp alicn
tsh avcb ccn日 e na lI heC leve landVAMedical o lherm e n
talh ealthprofessionalsont heus co fCESd uring
Ccl1tcrf o
rAl pha-Stimt reatm entf o
rpos t r
adiationd r y nc州 ,
、v
it he qu
allygoodr esults.
' )
:
;
t
h
h
y
c
p
r
n
a
o
p
t
ye
i
U芯 じons
crelaxeds
i
s
t
t
a
cn
t
t
l
eo
ye n thusias
ti
fmindandbodyt
c. CES i
ha ti
nducesap
scomplemen-
r
c
TI
cr
陀'
ea胞
tce1出
et
じt
二 山
f C
1凶 al じha
肌n 邑
侠es旧n
I
I】t h
eb r
ain.As叫 su eh】,はtc
1 anb cc on CON仁URRENTPHARMACOTHERAPY
引i
s d
cr
凹 c 、
d辻山t】川ndil'陀e仁t自O
印1mu fCES.B I
山ar
i
日nsw a
y 'sp a
叫tel
lle
陪 dDEEP
CESc anbeu sedwithpharmacologicthe
rapywith
outcon-
TMSt 阻echno ωlo g ydl
出
【if
白l
er円Sf
!
‘
'l
J
"附omo
H
(】 therl rans cran ialm agne t ic
じer
na bou
tp otc
ntia
l polyphannacy in
ter
aじt
ion
s.Howcvcr,
sti
mlllationa pp roac hcsb yl lsi
ngs cvcral DeepT防I Sc oils
i
tisimporta
nttoi nf
onl
lt h
ep ι
lti
enttha
tCESmayd ecre
ase
(tcrmedH c oil
s )r a
t h
ert h anas inglef oc
als t imulati on.T his
l
hcn eedfo1
'medica
lion
.Ast hcpatic
nt川 lp
roVC
S,b o
thlhe
i
sd esig nedt os timuluted ee pe
rb r
ainI esionsw ithou ti ncr eas-
cl
inic
ianandp a
tiet山 o
n uIdbeal e
rtforsymptomぉtha
tmay
Ingthee lectricu lH cldi ntcnsityofぉupe r
licialc orticalr egi ons
山 1i
cat
can eedforadosageadjustmcn
t
ore xcc日 iv elys ti mulatingf a
cialncr vcs.T yp ic a
lt rcatl1lent
prolocolじo ns i
s t s0 11
' 5-20s essio
ns,e<lchl astin g1 5-20min,
overac o urseo f3 -4w ee ks.DEEPTMSwasa p prov edb yI he
SElF-DIRECTEDHOMETREATMENT
FDAi n2 013f ort hctr eatm entofm aj o
rd epr essived iso rder
ori np atientswhod i
ct1 10
lr espon
dt oa nti dep ressan td r ugs Mostindivi
dualsarccnp a
bleofdoingscl
f -
dirc
ctc
dCESt her-
Int eEuropcanEconomicArca,i
h talぉoh a只 CEmarkingf or "pyathome.TheUSA山 t heonlycounlryinthew o
rldt ha
t
Al
P
l
a
zh
rki
e
n
i
s
hcUSAa
me
o
r'
n'
r
sd i s eae,a
s
sdisc~目 e , a
ep l a nned
n
u t
ism .b
dPTSD:a
i
pol
p
p
a
r
rd
ov
is
or
,
c
altr
ler.c
r烏omco
hro n
f
i
t
cp
h
c
ai
日 1
n
1
1
r
b
qUJl出 CESd
e
alicens
cdoned
e
dh
ai
l
ca
yd
e
l
t
v
h
u
i
c
r
i
c
a
n
e
r
sl
cp
gt
ob
ra
c
het
es
t
i
i
t
r
s
i
o
l
o
do
n
e
tIt
r
nl
.T
o3o
yb
r
ea
y
t
,0
me
1o
nt
nlheo
smayn
r4weeks,t h
e
r
nt
d
e
e
ro
eut
wot
f
o
o
,
thr
eet i
m出 p e
rwee kd uringamai nte
nancep h
asc.Thei ndi
vid
ualcana ls
ou scCESaぉ o r
tcnasn cc
u cu,a詩thc
rea r
cno
Cl
INICAl仁ONSIDERATIONSANDGUIDE
lINES
si
dee f
fect
sfrome xt
en deduse.This目 白 peci
alyb en
etic
ial
Toint
egr
ateCESi1
1toc
1in
icn
lprac
ticcwerccommendatr
ia
l fo
rl ho
seI nd
ividu
alsd iagnosedwithPTSD川 I do t
herswho
日 r
ic
softrca
tme
ntsInacJi
nIco
rofli
cctoev
alua
tcr山 p
onseぉ expe
riencepanicattac
k討り7
206 B
ioel
ectromagnei
tcandSu
btl
eEnergyMedi口 ne
F
eel
ing
sexpeT
ienceddu
rin
gCES
tr
ear
me n
ts t
age
s
D
osa
geeq
ualst
imei
nver
sel
ypr
opo
rti
ona
ltocur
re
ntle
vel
(
.
ie
.,J
ec
u
日rr
entr
equi
resl
ong
ertr
eat
men
ttimepe
rsess
ion
)
A
le
rt E
ner
get
icn
,o"br
a i
nfo
g",
V山o
niscl
ea
r,a
sifth
e
,
/ p
ati
en
tsle
pta
llnig
ht
,穴
, 、
、
、 Ugh
t
、、
,/
f
e e
l
ing
、、
、
、
、
ー
干ーー
---
He
avy
/gr
oggyo
,reu
pho
ricf
ee
lin
g
(
Nev
ersto
pher
e!
)
S
lee
py
S
ta
rt E
nd
2
0mi
nute
sto
,
o
rmoreho
urs
FIGURE1
9.5 C
rani
alckclro lh ~rapy s
tim
ul叫 i
ond
o叫 r
出 p
ons
ccu
rve
TheE
vol
uti
ono
fC日 n
ialE
lec
tro
the
rap
ySt
imu
lat
ion 209
0'
1p rcgnancyi nthemtandmightc ausesomem isca
rriages t8 03
9.MωaIJP.M山 ,川 印 刷 l 'EiectlU'i
f!
tl Je
v dica le.Pa
ris:1 78 4
espec iallyat 1000Hz,b u
tt hereisnoc vi d
e n
c eof己自totOXI
C
1
0.K al i nowsk yL .E lcじtric-collvulsi
ont hcrapyi nぽ hi70p
. b rc ni a
eff~cts. Thcr clevanccofthcsctindin
gs10humはIlSi sunknown [
..
ll
l1Ci'f19 3り2 :1232
Advcrsee ffec
tso fCESi nhumansoccuri nle山 than1% 11
.Ledl 1c S .La n an仁 川e c 1cc t
rique.Z t
scll rjitrE iectJυt he!
ofc a sesandt heyaremildands el
f-limi
ting.Thesei nclu
dc 1903 ;1 1(1): 37 ι削 403-1 0,
vcrtigo.s kini rri
tatio
na te l
cctrode引 t e
s,and hcadaches 1
2.LeducS,RouxeauA .I nl1uじI1CCd ur ythmee td cl ape r
io d持UI
Headaches and v e
rtigoa re u叫 l
all
ye xp erienced when thc lapn叫 u c
ri O lld c1 ・inh
i hitionp arIcsc oun
: mい】川口 m ittcnt sd e
curr enti ss ett ooh ighf orap art
iculari ndividu . Thesc
al has日 t en
si o n.CRSt'tl llcesSocB io!1 903、55(VIl- X):899-9 0 1
1
3.R oh i n川 '
[
1じh LG. E leclrica
l A l1al鼎~s;a, S leep, 川,,1
~ffccts rcsolv~ whent hccurrentisredllc~d orwuhinminute討
Res us【i t
ali o n.A ncsthes;a.NcwY ork:A pp1 eton;1 914
toh o ursf ollo wi
ngt reatmcnt
.I rr
itat
iona tt hee le
ctrode日 t
c 1
4.G ily arov北 Y VA, L i四 nt 記 vI M‘ ScgalYY 、Kiri1
lo vaZA
canbca voide dbyr n
ovinge lectrode
sarounds ligh
tlyd u
r- Elel'lmsoll: Klu
li:o
J
. -Fiz;%gIch 出 koye /ss ledovl/J1Iy e
11g 1
l rc叫m cnts.Nos cri
ousa dversee ffec
t shavec vc
rbeen (E!ec lr
ICS lcep: A C/i nical-Physiυlogi口If! t
ll
'('Suxati ol/)
re
目
no rtedfromu
〕
s
inf!CES.I
句 Moscow:1 9 58
1
5.K irs ch DL .J 11
t.S ci enceb eh ind Cnmia! Electmrhcm/ ハ
Sri
lll ul
alioJ1. 2ndc d
.E dm onl on:M edi calS copePuhl i sh in g
CONCLUSION
2似た
CESじ辻 nimprovet hes afctyandc ffective
nessoft reatmen t 16
. D川 j gc CH. E lcc
tl'os
l cc
p, c cc
J lroancぉIh出 ia, a nu c l cc-
foran xicty,i nsom
n iil,は ndd epres日iona sw e
lla sc ontribut e tron
eur a
ld iagnosticsa ndt hcrapeuti山 Forei gn 品 IBI lIl
1967ゴ(3) :4ι64
tot h
emanagemento fpa inando thcrd i
sorder
s.Whenp rc -
17
.I wtlnovぉkyA .Dod :
gcCH.E l c
ctroぉI ccpa nde lじct roancs thc民Ja
scribedf o
rhomeu se,p atie
nts山 ' eempowercdt or cgul叫 e
Theory山 l dc1ini
c a
lp rac
tice.F orei gnS iBul
c !1 9
6 8:4(2);1 - 64
thc
ir0¥¥'11moods,1 0overcomet heirsleepproblcmぉ.andman U~. lwanvo skyA .T r
a n
scr an
i a
le Jeじtro therapya nde le cl
ro an出 t he
aget heirownp ain,t huscnhancingoutcom出 Comparedt o si
a;Newa r
.山 I
S0 1b
' io medicalc ngin eering.IEEEC υnvenlwl I
othern euerost i
mul ationt echniquesf orb ra
inr epair,CESi s Virg
inia:C harlotte.
sviUe;April,1 9 71
noninvasi v
e.l e日 e x
p ensive,andcanbel lscdsafel
yi lndcon 19.C ollccredp cr
s o
n alp apcrぉo fA刊 c nT w ano v討ky .Acce ぉs mn
venientlybyp atie
n t
s川 homc.I tisu scf
lllbotha sana djunc t Numher g 4.2
.A r
tifacts
.D a taba 日 Thc 8akkcn Mu日 um
tomcd icationo rp sycho thcrapyora 品 astand-alo
net reatme nt Lihr
ary.M in neapolis,MN,USA.
20.Magora F , Bd 1crA .A la d
j emo ff し Ma goraA c ta l
Whilet hecf 1
icacyofCESi nc ancerando lherseriol
lsd i
s-
Ohservation民 o ne le c
lrica
llyi nd uced 叫e e pi nm an. BrJ
eases¥vi thpoorr espot】sestoc onventionalt reatmen1 i
只 C l
1r-
Anesrh1 CJ65;37:4g0,49J
ren
tly叫 I pportedo nlybya necdotalr eport
s.s uchpatientぉc an 21.McKenzi eRE.R osenthalSH,D r icssnerJ S.Somcp巳y c ho
ccrta
i nlyb enc
t i
tfromi t
sa l
羽1 i
ty【oimprovcmoodands lecp phyぉiologice rf
ectsn fc lcctri
calt ranscra川礼l只t i mLllat inn
出 w e
l la srelicvingp ain. (cl
cctl 叫c ep).AmeriC
、
'l1 (
ll Psychill trù メhsocia fioll 品 it.'IIf~fù
1
3.PozosRS、R
1 ichard叩 1A W ,K apla n H M.Modc0' 1pn 叫llC 50
.S mi thRB .J sm i
c r ocurrcnts timulutionc ffc c tiv ci np 山 nm an
liona nJ1 0じIIぉ o
fa c! i
ul1()fc lc
c troane s thc只iai nd ogs.A llcsrhe .
a gcment? An a dd itionalp c日 pCClivc.AmJ P ail “
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