Approach Blood Gases

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Approach Blood Gases

Venous Blood Gases

1. Check patient ID and date/time of the gas


2. Check the pH – are they acidotic or alkalotic?
3. Check the CO2 – CO2 is acidic
a. Low pH + high CO2 = respiratory acidosis
b. Low pH + low CO2 = metabolic acidosis
c. High pH + high CO2 = metabolic alkalosis + resp compensation
d. High pH + low CO2 = respiratory alkalosis
4. Check the HCO3 – HCO3 is alkalotic
a. If HCO3 follows the pH (both are high) = metabolic alkalosis
b. If HCO3 is opposite to the pH (e.g. low HCO3, high pH) = respiratory process with metabolic
compensation

When approaching an arterial blood gas, check the oxygen levels first

Anion Gap
Anion Gap = Na – (HCO3 + Cl)
Normal range 4-12

Causes of High Anion Gap


 Lactate
Left Total Knee  Toxins – ethanol, methanol, aspirin (salicylates)
Replacement ★  Ketones
 Renal – uraemia, renal tubular acidosis

 Cyanide, carbon monoxide


 Alcoholic ketoacidosis
 Toluene
 Methanol, metformin
 Uraemia
 Diabetic ketoacidosis
CAT MUDPILES
 Phenformin, pyroglutamic acid, paraldehyde, propylene glycol,
paracetamol
 Iron, isoniazid
 Lactate (numerous causes)
 Ethanol, ethylene glycol
 Salicylates (aspirin metabolism)

 Glycols (ethylene glycol and propylene glycol)


 Oxoproline (from panadol metabolism)
 L-Lactate
 D-Lactate
GOAL MARK
 Methanol
 Aspirin
 Renal Failure
 Ketoacidosis

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