Gi Pathogens Profile Sample Report

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Patient: Ima Sample

Pathogens Sample Accession: 00000000-0001


000000000-0003
Collected: 08/02/2022 Received: 08/3/2022
08/03/2022
DOB: 07/11/1981 Completed: 8/17/2022
8/22/2022
Gender: M Ordered by: Diane Farhi, MD
5894 Shiloh Rd, Ste 101 | Alpharetta GA 30005
877.485.5336
DNADN
STAOSO
TLOA
ONLAALNYASLIS
YSBIY
SQBY
UAQNUTAIT
NATT
ITIV
AETIP
VCERPCR

YOUR PERSONALIZED REPORT


YOUR PERSONALIZED REPORT
PATHOGENS
PATHOGENS

The GI-MAP® includes pathogens (bacterial, parasitic and viral) commonly known to cause gastroenteritis. Note that
Theall
not GI-MAP® includes
individuals pathogens
with positive (bacterial,
findings parasitic
will present withand viral) commonly
symptoms. knownincluding
Many factors, to causethe
gastroenteritis.
health of theNote that
individual
not allas
(such individuals with positive
immune health, findings
digestive will present
function, with symptoms.
and microbiome Many
balance), thefactors, including
transient themost
nature of health of the individual
pathogens, and the
(such as immune health, digestive function, and microbiome balance), the transient nature of most pathogens,
presence and expression of virulence factors, all contribute to pathogen virulence and individual symptoms. and the
presence and expression of virulence factors, all contribute to pathogen virulence and individual symptoms.
BACTERIAL PATHOGENS Result Reference
BACTERIAL PATHOGENS Result Reference
Campylobacter
Campylobacter < dl < 1.00e3
< dl < 1.00e3
C. difficile Toxin
C. difficile Toxin A
A 1.21e5
< dl
High ↑
< 1.00e3
< 1.00e3
C. difficile Toxin
C. difficile Toxin B
B 2.27e5
< dl
High ↑
< 1.00e3
< 1.00e3
Enterohemorrhagic
Enterohemorrhagic E. E. coli
coli < dl
< dl < 1.00e3
< 1.00e3
E. coli O157
E. coli O157 < dl
< dl < 1.00e3
< 1.00e3
Enteroinvasive
Enteroinvasive E.
E. coli/Shigella
coli/Shigella < dl
< dl < 1.00e3
< 1.00e2
Enterotoxigenic
Enterotoxigenic E. coli LT/ST
E. coli LT/ST < dl
< dl < 1.00e3
< 1.00e3
Shiga-like
Shiga-like Toxin E. coli stx1
Toxin E. coli stx1 < dl
< dl < 1.00e3
< 1.00e3
Shiga-like
Shiga-like Toxin
Toxin E. coli stx2
E. coli stx2 < dl
< dl < 1.00e3
< 1.00e3
Salmonella
Salmonella < dl
< dl < 1.00e4
< 1.00e4
Vibrio
Vibrio cholerae
cholerae < dl < dl < 1.00e5
< 1.00e5
Yersinia
Yersinia enterocolitica
enterocolitica 4.46e3 < dl < 1.00e5
< 1.00e5
PARASITIC PATHOGENS
PARASITIC PATHOGENS
Cryptosporidium
Cryptosporidium < dl < dl < 1.00e6
< 1.00e6
Entamoeba
Entamoeba histolytica
histolytica < dl < dl < 1.00e4
< 1.00e4
Giardia
Giardia < dl < dl < 5.00e3
< 5.00e3
VIRAL PATHOGENS
VIRAL PATHOGENS
Adenovirus
Adenovirus 40/41
40/41 < dl < dl < 1.00e10
< 1.00e10
Norovirus
Norovirus GI/II
GI/II < dl < dl < 1.00e7
< 1.00e7

KEY: Results are


Results are reported
reported as
as genome
genome equivalents
equivalents per
per gram
gram of
of stool,
stool, which
which is
is a
a standard
standard method
method for
for estimating
estimating the
the number
number of
of
KEY:
microbes measured per gram of stool, based on qPCR analysis of DNA samples.
microbes measured per gram of stool, based on qPCR analysis of DNA samples.
7
Results are
Results are expressed
expressed in
in standard
standard scientific
scientific notation.
notation. For
For example,
example, a
a reported
reported result
result of
of 3.5e7
3.5e7 is
is equivalent
equivalent to
to 3.5
3.5 xx 10
107
microbes
microbes per
per gram,
gram, which
which equals
equals 35,000,000
35,000,000 (35
(35 million)
million) microbes
microbes per
per gram
gram of
of stool.
stool.
<
< dl
dl represents
represents results
results below
below detectable
detectable limit.
limit.

The assays were developed and/or the performance characteristics CLIA# 11D-2097795
determined by Diagnostic Solutions Laboratory. Medical Director - Diane Farhi, MD
1
Patient: Ima Sample
Pathogens Sample Accession: 00000000-0001
000000000-0003
HELICOBACTER PYLORI

H. PYLORI & VIRULENCE FACTORS Result Result Reference


Reference

Helicobacter pylori 2.90e3 High ↑


6.55e2 < 1.00e3
< 1.00e3
Virulence Factor, babA Positive Negative Negative
Negative
Virulence Factor, cagA Positive Negative Negative
Negative
Virulence Factor, dupA Negative Negative Negative
Negative
Virulence Factor, iceA Negative Negative Negative
Negative
Virulence Factor, oipA Negative Negative Negative
Negative
Virulence Factor, vacA Negative Negative Negative
Negative
Virulence Factor, virB Positive Negative Negative
Negative
Virulence Factor, virD Positive Negative Negative
Negative

COMMENSAL/KEYSTONE BACTERIA
COMMENSAL BACTERIA Result Reference

Bacteroides fragilis 8.98e10 1.6e91.6e9


- 2.5e11org/g
- 2.5e11
Patient: Ima Sample Accession: 00000000-0001
Bifidobacterium spp. 1.89e10 > 6.7e7org/g
> 6.7e7
H.
H. PYLORI
PYLORI ANTIBIOTIC
ANTIBIOTIC RESISTANCE
RESISTANCE GENES
GENES
Enterococcus spp. 2.45e7 1.9e51.9e5
- 2.0e8org/g
- 2.0e8
Result Reference Result Reference
Result Reference Result Reference
Amoxicillin spp.
Escherichia 2.14e8 3.7e63.7e6
- 3.8e9org/g
- 3.8e9
Amoxicillin Positive
Negative Negative
Negative Clarithromycin
Clarithromycin Positive
Negative Negative
Negative
Genes associated with amoxicillin resistance Genes associated with clarithromycin resistance
Genes associatedspp.
Lactobacillus with amoxicillin resistance 6.55e6 Genes associated with clarithromycin resistance 8.6e58.6e5
- 6.2e8org/g
- 6.2e8
PBP1A Present Absent
PBP1A S414RS414R Absent A2142C
A2142C Absent
Enterobacter
PBP1A spp. Absent 2.07e6 Absent 1.0e61.0e6
- 5.0e7org/g
- 5.0e7
PBP1A T556ST556S Absent A2142G
A2142G Absent
PBP1A muciniphila Absent
PBP1A N562Y
Akkermansia
N562Y Absent <1.00e2
<dl L A2143G
A2143G
Present
Absent 1.0e11.0e1
- 8.2e6org/g
- 8.2e6

Faecalibacterium prausnitzii 5.66e5 1.0e31.0e3


- 5.0e8org/g
- 5.0e8
Result Reference Result Reference
Result Reference Result Reference
Roseburia spp.
Fluoroquinolones
Fluoroquinolones Negative
Negative
7.91e5
7.91e5
L
Negative
Negative
Tetracycline
Tetracycline
Negative 5.0e75.0e7
Negative
-Negative
2.0e10org/g
- 2.0e10
Negative
Genes associated with fluoroquinolone resistance Genes associated with tetracycline resistance
Genes associated with fluoroquinolone resistance Genes associated with tetracycline resistance
gyrA Absent A926G Absent
gyrA N87K
BACTERIALN87K
PHYLA Absent A926G Absent
gyrA Absent AGA926-928TTC Absent
gyrA D91N
D91G
Bacteroidetes Absent 1.21e12 AGA926-928TTC Absent 8.6e11
8.6e11
- 3.3e12org/g
- 3.3e12
gyrA Absent
gyrA D91G
D91N Absent
Firmicutes 4.70e10
4.70e10
L 5.7e10
5.7e10
- 3.0e11org/g
- 3.0e11
gyrB Absent
gyrB S479N
S479N Absent
Firmicutes:Bacteroidetes
gyrB Ratio
Absent 0.04 < 1.0
gyrB R484K
R484K Absent

The assays were developed and/or the performance characteristics CLIA# 11D-2097795
determined by Diagnostic Solutions Laboratory. Medical Director - Diane Farhi, MD
2

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