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10 - Treatment Modalities Lec 10
10 - Treatment Modalities Lec 10
1. The nurse should administer any drug ONLY WITH A written order.
2. Consult the doctor when in doubt
3. All medications given must be charted on the patient's case record sheet.
4. Always address the patient by name and make certain of his identification
5. Do not leave the patient until the drug is swallowed
6. Do not permit the patient to go to the bathroom to take the medication
7. Do not leave the tray within the reach of the patient.
8. Bottles should be tightly closed and labeled
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a. Antipsychotics also known as neuroleptics
The first of the antipsychotics (also known as neuroleptics), chlorpromazine, was introduced in 1951 for
anesthetic premedication and was noted to reduce delusions and hallucinations in schizophrenia.
Classified to ________Classical ________and _________atypical
• Chlorpromazine • Clozapine
• Promazine • Risperidone
• Triflupromazine • Olanzapine
• Thioridazine • Quetiapine
• Stelazine Trifluoperazine • Ziprasidone
• Fluphenazine • Aripiprazole
• Prochlorperazine • Pimozide
• Loxapine • Parliperidone
• Haloperidol • Sertindole
• Droperidol • Zotepine
Indications
1- Organic psychiatric disorders
• Delirium
• Dementia
• Delirium tremens
• Drug-induced psychosis
2- Psychiatric disorders
• Schizophrenia
• Mania
• Major depression with psychotic symptoms
3- Childhood disorders
• Attention-deficit hyperactivity disorder
• Autism
• Conduct disorder
4- Medical disorders
• Tic disorder
Adverse Effects of Antipsychotic Drugs
Extrapyramidal symptoms (EPS)
1. Neuroleptic-induced parkinsonism:
2. Acute dystonia:
3. Akathisia:
4. Tardive dyskinesia:
5. Neuroleptic malignant syndrome
Nurse's Responsibility for a Patient Receiving Antipsychotics
1. Instruct the patient to take sips of water frequently to relieve dryness of mouth.
2. A high-fiber diet, increased fluid intake
3. Advise the patient to get up from the bed or chair very slowly.
4. Observe the patient regularly for abnormal movements.
5. Patient should be warned about driving a car or operating machinery when first treated with
antipsychotics.
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b. Antidepressants
Types
i. Monoamine oxidase MAOI’s e.g. (Phenelzine, Isocarboxazid, tranylcypromine)
ii. Tricyclic Antidepressants TCA’s e.g. (Amitryptiline, Clomipramine, Imipramine
Trimipramine)
iii. Selective serotonin reuptake Antidepressants SSRI’s e.g. (Citalopram and
Escitalopram, Flouxetine, Fluvoxamine, Paroxetine, Sertraline)
iv. Atypical Antidepressants e.g. (Trazadone, Amineptine, Bupropion).
Indications
Depressive Disorders
Childhood psychiatric disorders (Separation anxiety disorder, School phobia, Night terrors)
Anxiety disorders & OCD
Side Effects
1. Autonomic side-effects: Dry mouth, constipation, mydriasis, urinary retention,
orthostatic hypotension, impotence, impaired ejaculation.
2. CNS effects: Sedation, tremor, seizures, precipitation of mania.
4. Allergic side-effects
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d. Anxiolytics
Benzodiazepines:
Chlordiazepoxide
Diazepam
Oxazepam
Chlorazepate
Lorazepam
Halazepam
Alprazolam
Indications
• Anxiety disorders and Obsessive-compulsive disorder (OCD)
• Insomnia
• Depression
• Post-traumatic stress disorder
2- Electroconvulsive Therapy
The lecture in the clinical
3- Psychosurgery
"a surgical intervention, to destroy fibers connecting one part of the brain with another
with the intent of modifying behavior, thought or mood disturbances.