Medical Neuroscience

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Brain Parts

⼀ pocessidg
訂 morion

堞 。
|

Recogmizing
integralion of
Objecrs emorions

Neuronsi primary
processors of signals
neural

0
similar to somaric cells

L, but
diversiry of formslmouphology

i
by diff
)s contribured dendvies
;
.

,
bioelectrica

specializarions fo intercellular communicalion


.


mecieve
signalsfrom othr heurons
*
Dendrires

↑↑ ERs & mitochondria


'


, 0

I
b ,
spines increasesurface

generG⻜努 area
)
aclion porential lelectvicity
a
flow of info
diffev in
length a
wheve 于 ↑
sigmals
← 化 locaes
(, absence of spines
⽜ imhisirs om cells they make commelion

→ release neurotramsuiates
Input & Output

Conducting Zone

.
Efferent :

signals come owt


of central nervous
system
b axon 5 info goes away

Afferent central
signals go
in nervous
system
. :

4 dendrite t
info comes in

σ
统⼀束
七-fferen
Brain

Afferenr

Vascular Endothelium provides forthe


supply of
; blood to brain tissae

( provides
gray
e white matter wl nutrient
Neuroglia :

suppore electrical & chemical funcrions of neurons

1 .

supporr metabolic &


sigmaling funclions

2 , neuvon circur formarion &


synaptic plasviciny
3 , mnke myelin

4 .
blood brainbavrie

5 ,

inflammalory vesponse in
injuved nearal tissne

6 .
formalion of scar tissue

type
1 .

Astrocyte
P

1
in matter
gray


maintain ionic balane


of extiacollularfluids

pocessneurotransmirlers

,

G assisr formnlion of synapse


& civcnl


form blood -brainbarrie


help form scar tissue

2 .

Oligodendroyte

hipgf
huausmrgiaor

brnntaitMij
suismiro

"
G Schwamn cells make
myelin in
body )

myelin
5
help send signals alongaxon !

nas
pin frasifinoninsinfnn
Hsome are
subjeortoimmunological atlacks

of conducling signals
lossinefficiency in
4

axons
D

leakiness

myelin deveasofmombrnne
-
t
"

Nodes of "

Ranvier
ions
efficienly
fpump
Cell
3 .

Microglial
0

1
type of mononudear
phagocyte
③ derive from hematopoieric cell that
migrales
to brain



Ramified form ( dormant form)


Amoeboid Form

3 activated
microglial secrete
signaling
molecules
loytokines)
cetinjury
"

happens . .
modulale local
isflammatory response

sevvesasa
macrophage

in Cos
4 .
Glial stem Cell

immature cells
D
specialized nenroglial Existingneurons
② near rentvicles & blood vessels New heurons

has

properries of somalic stem cells Glial stem Cell
Blood Vessel
aproliferalion
.
self -
renewal

.
can make all cells of a risshe

5 .

Oligodendrocyte Precursr

D
in white mallr

0
mainly give rise to
oligodendrocyte
☆ Blood Brain Barrier
D excludes
large watev soluable

molecules & toxic compounds into COS

③ inhibils some pharmaceuricul ageuts


seal
spaces between
of
overlaping regions
ondithdialall & itscapillary
)
Brain Orientation
precentva
、 的
vus
superiontrontal
lobe

88
-

i
$
" 「
central
" "

bqnd}
……
smioddle
^ "
Medial

Posterior Lateral

I

_

… lCauda)
( Rostral) inferior

suitan
ggrus
vietallobule
lateral

occipitalobkllongerinlefr
fissuv
Xinfeviov
hemi spherelocessinglangaage )

Midsagietal Plane

iniin
i

"
"
…i ^

"
"

pnoai
(
m mn
…考⼀⼚州
$

mmi,'眾感
訂 — → Ceitw的l

A
"
Sulcus

(* I
"
Lonneus parieto
(3
olundary of&the
Parietal lobe occipita) Yobse)

" Lacnritoniteeningrn
-
occipitalsulcus

Cowp

medial surfae of occi lobe
11
,

" osam
( mhite matter}
sprni

" 、 瀆喲

☆ Gyrus =
⼀塊 sulcus :
spale between

gyrus


/200

Dorsal
* : to theback( inferior / candal)

* Ventral : nteriora
"
Finding Central sulcas (check 1 ateral surface了

gnI

branch

"
"

-
" tissue over brain =
Grachnoid
4, cevebral cortex
buffering spae ovev

gyrusis formed by the


growth morphogenesis of
central &
" &
precentral poctcentra gyrus
ateral olfactory Track

9 Ventval surface

rbitalcorx 凍
Λ
tempoval
lobe
0了。
— OpticChiasim


Cevebral nypothalamas
Bzaingtem
Peduncles

( parr of midlbrain) pituitaryaatttach 5o


uypo )
.

☆ connecls Mindbraim
& spinal covd

J whire matter

Corticospinatracr
B Eouhains fibevs of
Medulla
m起Corlex
senad

aaxons olowwn Pyramids
stemfcerebellum
ospinalcord commects braim

“鸞
Blood Supply

InternalCavolid

rmmonicning
Posrenior
ieo —
airery9 3 anteriov circulalion

orieinI
onsiignoanait

Superi√

Cerebellar
" 3 rum s
: lomard midsrain

— wena

Fufeiov ⼀ Posteviovcivculalioon
3


Anterior
SuPPozlS
Arrariesoms
Cereyellar
,
inferin
posreriov arlery
cerebellum

supplies blood
to

poszaiom f infeion sidl

ofbrain
3 bas bran ches than supplies
medulla

闷f
Supplies

nmnimes
— finneiarsminaray
𠃌

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